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世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 17-17页

作者： Hedera P. Fenichel G.M. Blair M. haines j.l. 郭俊 Department of Neurology Vanderbilt University 6140 MRB III 4 65 21st Ave S Nashville TN 37232-8552 United States Dr.

Background: Mutations in a novel GTPase gene SPG3A cause an autosomal dominant hereditary spastic paraplegia linked to chromosome 14q (SPG3), which accounts f or approximately 10%to 15%of all autosomal dominant hereditary spastic paraple gia cases. The mutational spectrum of the SPG3A gene and the phenotype/genotype correlations have not yet been established. Objective: To describe a kindred wit h an infantile onset of hereditary spastic paraplegia caused by a novel mutation in the SPG3A gene. Patients: Complete neurological examination and genetic anal ysis were performed on 6 affected members of a small African American kindred. l inkage analysis to genetic markers near autosomal dominant hereditary spastic pa raplegia loci on chromosomes 2p and 14q was performed. The coding sequence of th e SPG3A gene was analyzed, and the identified change in the sequence was tested for being a benign polymorphism by sequencing 200 chromosomes from normal contro ls. Results: Every affected individual had signs of uncomplicated spastic parapa resis without additional neurological abnormalities. None of the affected family members had ever walked normally. The history was consistent with an infantile onset, despite the normal acquisition of motor milestones. Genetic analysis sugg ested linkage to the SPG3A locus on chromosome 14q. Analysis of the SPG3A gene r evealed a missense mutation C635T, predicted to result in a threonine to isoleuc ine substitution at codon 156. Analysis of 200 normal chromosomes did not identi fy the same change in healthy subjects. Conclusion: We report a novel muta tion in the SPG3A gene in an African American family with an infantile onset of auto somal dominant hereditary spastic paraplegia.

关键词： SPG3A 痉挛性截瘫遗传学分析突变谱编码序列婴儿期连锁分析遗传标记物健康受试者检查和

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Pregnancies from subzonal insemination of unfertilized oocytes after conventional IVF

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Chinese Medical journal 1997年第6期110卷 81-83页

作者： E.P.l.loong T.T.Y.Chiu C.j.haines Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong

ＰｒｅｇｎａｎｃｉｅｓｆｒｏｍｓｕｂｚｏｎａｌｉｎｓｅｍｉｎａｔｉｏｎｏｆｕｎｆｅｒｔｉｌｉｚｅｄｏｏｃｙｔｅｓａｆｔｅｒｃｏｎｖｅｎｔｉｏｎａｌＩＶＦＥ．Ｐ．Ｌ．Ｌｏｏｎｇ，Ｔ．Ｔ．Ｙ．ＣｈｉｕａｎｄＣ．Ｊ．Ｈａｉ... 详细信息

ＰｒｅｇｎａｎｃｉｅｓｆｒｏｍｓｕｂｚｏｎａｌｉｎｓｅｍｉｎａｔｉｏｎｏｆｕｎｆｅｒｔｉｌｉｚｅｄｏｏｃｙｔｅｓａｆｔｅｒｃｏｎｖｅｎｔｉｏｎａｌＩＶＦＥ．Ｐ．Ｌ．Ｌｏｏｎｇ，Ｔ．Ｔ．Ｙ．ＣｈｉｕａｎｄＣ．Ｊ．ＨａｉｎｅｓｂｊｅｃｔｉｖｅＴｏｅｖａｌ...

关键词： INTRACYTOPlASMIC SPERM INjECTION IN-VITRO FERTIlIZATION INVITRO REINSEMINATION PENETRATION ClEAVAGE SUZI ICSI

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各向异性、横向非均匀介质中的传播不变量、透射和反射

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世界地震译丛 1994年第2期25卷 52-58页

作者： B.l.N.Kennett K.Koketsu A.j.haines 梁慧云国家地震局地球物理勘探大队

对于地震波主要特性随深度变化的准层状介质,可根据两个地震波场的位移和作用力的某种组合建立传播不变量计算公式。这样的不变量与深度无关,对于相同的场则趋于零。它是在空间和波数域中为各向异性和横向变化介质而建立的一种计算方法... 详细信息

对于地震波主要特性随深度变化的准层状介质,可根据两个地震波场的位移和作用力的某种组合建立传播不变量计算公式。这样的不变量与深度无关,对于相同的场则趋于零。它是在空间和波数域中为各向异性和横向变化介质而建立的一种计算方法。这些传播不变量可大大简化横向变化介质中反射和透射过程的综合分析,其中包括了波数间耦合作用的计算。本文通过分析 SH 波在自由表面下的非规则界面上的入射过程,阐明了这种方法的实现过程。其结果与用其他方法得出的极其一致,而且少用20%左右的计算时间。而在更为复杂的计算模型中,这种方法甚至还能更多地提高计算速度。

关键词：地震波非均匀介质传播不变量

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The demands of the extra-time period of soccer:A systematic review

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journal of Sport and Health Science 2022年第3期11卷 403-414页

作者： Adam Field Robert joseph Naughton Matthew haines Steve lui liam David Corr Mark Russell Richard Michael Page liam David Harper School of Human and Health Sciences University of HuddersfieldHuddersfieldHD13DHUK School of Social and Health Sciences Leeds Trinity UniversityBrownberrie LaneHorsforthLeedsLS185HDUK Department of Sport&Physical Activity Edge Hill UniversitySt.Helens RoadOrmskirkLancashireL394QPUK

Background:Soccer match-play is typically contested over 90 min;however,in some cup and tournament scenarios,when matches are tied,they proceed to an additional 30 min,which is termed "extra-time^(ET).This systematic review sought to appraise the literature available on 120-min of soccer-specific exercise,with a view to identifying practical recommendations and future research ***:The review was conducted according to the PRISMA *** researchers performed a systematic search of PubMed,CINAHl,and PsycINFO in May 2019,with the following keywords entered in various combinations:"soccer","football","extra-time","extra time","extratime","120 minutes","120 min","additional 30 minutes",and "additional 30 min".Results:The search yielded an initial 73 *** the screening process,11 articles were accepted for *** were subsequently organized into the following 5 categories:movement demands of ET,performance responses to ET,physiological and neuromuscular response during ET,nutritional interventions,and recovery and *** results highlighted that during competitive match-play,players cover5%-12% less distance relative to match duration(i.e.,meters per minute) during ET compared to the preceding 90 *** in technical performance(i.e.,shot speed,number of passes and dribbles) were also observed during ***,carbohydrate provision may attenuate and improve dribbling performance during ***,objective and subjective measures of recovery may be further compromised following ET when compared to 90 ***:Additional investigations are warranted to further substantiate these findings and identify interventions to improve performance during ET.

关键词： Movement demands Neuromuscular fatigue Nutritional intervention Performance Physiology

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Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATlAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.j. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios l. Adamczyk S.V. Addepalli M.j. Addison j. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras j. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.l. Alberghi j. Albert P. Albicocco G.l. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.j. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke j.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen j.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki j.A. Aparisi Pozo M.A. Aparo l. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.j. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena j-F. Arguin S. Argyropoulos j.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah j. Assahsah K. Assamagan R. Astalos S. Atashi R.j. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.j. Bailey V.R. Bailey j.T. Baines l. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli l.M. Baltes W.K. Balunas j. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal l. Barak M. Barakat E.l. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATlAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATlAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATlAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATlAS jET QUARK GlUON TAGGING

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Developing one-dimensional implosions for inertial confinement fusion science

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High Power laser Science and Engineering 2016年第4期4卷 1-7页

作者： j.l.Kline S.A.Yi A.N.Simakov R.E.Olson D.C.Wilson G.A.Kyrala T.S.Perry S.H.Batha E.l.Dewald j.E.Ralph D.j.Strozzi A.G.MacPhee D.A.Callahan D.Hinkel O.A.Hurricane R.j.l.eper A.B.Zylstra R.R.Peterson B.M.haines l.Yin P.A.Bradley R.C.Shah T.Braun j.Biener B.j.Kozioziemski j.D.Sater M.M.Biener A.V.Hamza A.Nikroo l.F.Berzak Hopkins D.Ho S.lePape N.B.Meezan D.S.Montgomery W.S.Daughton E.C.Merritt T.Cardenas E.S.Dodd los Alamos National laboratory lawrence livermore National laboratory

Experiments on the National Ignition Facility show that multi-dimensional effects currently dominate the implosion performance. low mode implosion symmetry and hydrodynamic instabilities seeded by capsule mounting features appear to be two key limiting factors for implosion performance. One reason these factors have a large impact on the performance of inertial confinement fusion implosions is the high convergence required to achieve high fusion *** tackle these problems, a predictable implosion platform is needed meaning experiments must trade-off high gain for performance. lANl has adopted three main approaches to develop a one-dimensional(1D) implosion platform where 1D means measured yield over the 1D clean calculation. A high adiabat, low convergence platform is being developed using beryllium capsules enabling larger case-to-capsule ratios to improve symmetry. The second approach is liquid fuel layers using wetted foam targets. With liquid fuel layers, the implosion convergence can be controlled via the initial vapor pressure set by the target fielding temperature. The last method is double shell targets. For double shells, the smaller inner shell houses the DT fuel and the convergence of this cavity is relatively small compared to hot spot ignition. However,double shell targets have a different set of trade-off versus advantages. Details for each of these approaches are described.

关键词： beryllium capsules double shells inertial confinement fusion liquid layers

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Involvement of lipid Rafts and Cellular Actin in AcMNPV GP64 Distribution and Virus Budding

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Virologica Sinica 2009年第4期24卷 333-349页

作者： F. j. haines C. M. Griffiths R. D. Possee C. R. Hawes l. A. King School of life Science Oxford Brookes University Veterinary laboratories Agency-Wey-bridge New Haw Addlestone Surrey KT15 3NB UK. NERC Centre for Ecology & Hydrology (Oxford)

GP64 is the major envelope glycoprotein associated with the budded virus (BV) of Autographa californica nucleopolyhedrovirus (AcMNPV) and is essential for attachment and budding of BV particles. Confocal microscopy and flotation assays established the presence of lipid raft domains within the plasma membranes of AcMNPV-infected Sf9 cells and suggested the association of GP64 with lipid rafts during infection. GP64 and filamentous actin (F-actin) were found to co-localise at the cell cortex at 24 and 48 hpi and an additional restructuring of F-actin during infection was visualised, resulting in a strongly polarised distribution of both F-actin and GP64 at the cell cortex. Depletion of F-actin, achieved by treatment of Sf9 cells with latrunculin B (lB), resulted in the redistribution of GP64 with significant cytoplasmic aggregation and reduced presence at the plasma membrane. Treatment with lB also resulted in reduced production of BV in Sf9 cells. Analysis of virus gene transcription confirmed this reduction was not due to decreased trafficking of nucleocapsids to the nucleus or to decreased production of infectious progeny nucleocapsids. Reduced BV production due to a lack of GP64 at the plasma membrane of AcMNPV-infected Sf9 cells treated with lB, suggests a key role for F-actin in the egress of BV.

关键词： Autographa californica nucleopolyhedrovirus (AcMNPV) Actin lipid rafts Egress

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施肥增加火炬松的生长与地面覆盖

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湖南林业科技 1981年第4期 41-43页

作者： l.Wayne haines Sharon G haines 李果明

在美国东南部,大都认为施肥是一项增加木材产量的营林措施。在东南地区,氮(N)磷(P)和钾(K)曾分别或合并施用于200,000公顷以上的火炬松(PinusTaeda l.)和湿地松(*** var elliottii)人工林。不过,要

关键词：火炬松北美刺果松地面覆盖保护地平均树高

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施肥对11年生火炬松人工林菌根数量和林木生长的影响

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贵州林业科技 1983年第S1期 7-13页

作者： j.A.Menge l.F.Grand l.W.haines 管国利

在11年生火炬松(Pinus taeda l.)人工林里进行的施肥研究中、我们发现除施N+P+K肥小区外,所有施N肥小区的菌根根尖数,都少于对照及只施p肥小区的菌根根尖数。由于单独施P肥对菌根根尖数量无影响,所以同时施N肥和P肥时,菌根根尖少,可认为... 详细信息

在11年生火炬松(Pinus taeda l.)人工林里进行的施肥研究中、我们发现除施N+P+K肥小区外,所有施N肥小区的菌根根尖数,都少于对照及只施p肥小区的菌根根尖数。由于单独施P肥对菌根根尖数量无影响,所以同时施N肥和P肥时,菌根根尖少,可认为N肥是其主要原因。

关键词：菌根根尖小区火炬松人工林林木生长

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在甲酸和酶处理的青贮料中增补适量蛋白质对青年牛利用率的影响

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河南科技大学学报（农学版） 1994年第2期18卷 53-58页

作者： j.l.jACOBS M.j.haines A.B.MCAllAN 陈菊娥衡葡萄

用多年生黑麦草制成三种青贮料:不加任何添加剂(u),甲酸作添加剂(F),半细胞和细胞混合酶作添加剂(E)。通过对青贮饲料分析表明:对照组和酶处理组的青贮料中比用甲酸处理的乳酸含量高。酶处理过的青贮料和其它两组相比有较低的酸性纤维(... 详细信息

用多年生黑麦草制成三种青贮料:不加任何添加剂(u),甲酸作添加剂(F),半细胞和细胞混合酶作添加剂(E)。通过对青贮饲料分析表明:对照组和酶处理组的青贮料中比用甲酸处理的乳酸含量高。酶处理过的青贮料和其它两组相比有较低的酸性纤维(ADF)和中性纤维(NDF),但有较高的残余水溶性碳水化合物(WSC)。用这些青贮料并分别添加含N量相同的油菜饼(RSN)(60g/kg)或鱼粉(FM)喂牛,这样可得到六种食物组合(uR,uF,ER,EF,FR,FF),牛对有机物质的吸收利用量是相似的。但经酶处理的青贮料中ADF的吸收量则很低(P<0.001)uR,11631;uF,1160;ER,1104;EF,1035;FR,1216;FF,1213),对NDF的吸收量也具有同样的规律性(P<0.01)(uR,1946;uF,1955;ER,1877;EF,1772;FR,2031;FF,2041)。显而易见,整个消化管对经酶处理过的有机物的消化能力显著提高(P<0.001)(uR,0.644;uF,0.644;ER,0.668;EF,0.678;FR,0.633;FF,0.633)。对牛增重的影响一般是经酶或甲酶处理并添加油菜饼的青贮料远大于鱼粉的,而酶处理和甲酸处理两者差异不显著。

关键词：青贮料酶处理蛋白质添加剂甲酸处理蛋白质补充青年牛多年生黑麦草消化力体重增加水溶性碳水化合物

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