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Effects of Addition of Amino Acids or Soybean Phospholipid in Diet on Slaughter Performance and Meat Quality of Pigs

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Asian Agricultural Research 2023年第4期15卷 40-43页

作者： Sicong LUO Shaobo LI Xiangyun HU Min CHEN Lingxiu GAN Tingju HUANG Wenjie LU Junxiang HUANG haimei deng Jiahuang YANG Cui YANG Xiuliang LI Guangxi Vocational University of Agriculture Nanning 530007China

[Objectives]The study aims to discuss the effects of addition of arginine and glutamic acid or soybean phospholipid,vitamin E and yeast selenium in diet on the slaughter performance and meat quality of long(white)×large(York)binary hybrid pigs.[Methods]27 long×large castrated hybrid boars with the body weight of(54.4±0.15)kg were randomly divided into 3 groups,with 3 replicates per group and 3 pigs per *** A was the control group,in which the pigs were fed basal diet;in group B,0.8%arginine and 0.60%glutamate were added to the basal diet;in group C,75 g of soybean phospholipid,20 g of vitamin E and 8 g of yeast selenium were added to every 100 kg of the basal *** trial period was 60 *** the experiment was ended,one test pig with similar body weight was selected from each replicate for slaughter and meat determination.[Results]The average weight gain and eye muscle area of the pigs in group B were significantly higher than those in group C(P0.05);there was no significant difference between group B or C and group A in the average weight gain and eye muscle area(P>0.05).There was no significant difference in other slaughter performance between the three groups(P>0.05).Besides,there was also no significant difference in the content of various amino acids,total amino acids and total umami amino acids between the three groups(P>0.05).The inosine content in the longissimus dorsi muscle and muscle cooking loss of binary hybrid pigs in group C were significantly better than those in group B(P0.05);there was no significant difference between group B or C and group A in the inosine content and muscle cooking loss of the pigs(P>0.05).In addition,there was no significant difference in other meat traits and chemical composition of the

关键词： Slaughter performance Meat quality Arginine Glutamic acid Soybean phospholipid Long×large binary hybrid pigs

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红龙果引种观察及丰产栽培技术

北京农业（下旬刊） 2008年第7期 23-25页

作者：邓海梅李长安廖爱华广西壮族自治区畜牧研究所广西南宁530001

2003年在广西畜牧研究所对引进的红皮红肉和红皮白肉2个红龙果品系,进行了系统观察和早结丰产栽培技术试验。结果表明,红皮白肉坐果率高达93%以上,易获得丰产,平均单果350g,可溶性固形物14%,可食率83.1%;而红皮红肉在自然授粉情况下,坐... 详细信息

2003年在广西畜牧研究所对引进的红皮红肉和红皮白肉2个红龙果品系,进行了系统观察和早结丰产栽培技术试验。结果表明,红皮白肉坐果率高达93%以上,易获得丰产,平均单果350g,可溶性固形物14%,可食率83.1%;而红皮红肉在自然授粉情况下,坐果率仅12%,产量较低,平均单果180g,可溶性固形物16%,可食率86.3%。在0～3℃持续15d条件下,红皮红肉老熟结果母枝冻死达93%以上,而红皮白肉抗寒性较强,仅有少量嫩梢受冻害。2品系采果期长,病虫害少,耐旱不耐涝。通过合理密植、科学修剪和合理的施肥等栽培技术可获得早结丰产的效果。

关键词：红龙果引种观察早结丰产栽培

甘肃地区581例川崎病患儿流行病学特征分析

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中国全科医学 2021年第35期24卷 4499-4505页

作者：吴谨志邓海梅闵丽王晋牛少敏刘亚红杨轶男董湘玉兰州大学第二医院小儿心血管科甘肃省兰州市730030

背景川崎病(KD)是一种与冠状动脉病变(CAL)相关的系统性血管炎,可导致心肌病、心肌梗死甚至死亡。目前,KD发病率逐年攀升,已成为儿童获得性心脏病最常见的病因,显著影响成年后个体远期心血管疾病的发生。因此了解该病的流行病学特征以... 详细信息

背景川崎病(KD)是一种与冠状动脉病变(CAL)相关的系统性血管炎,可导致心肌病、心肌梗死甚至死亡。目前,KD发病率逐年攀升,已成为儿童获得性心脏病最常见的病因,显著影响成年后个体远期心血管疾病的发生。因此了解该病的流行病学特征以及影响因素对降低疾病发生率有重要意义。目的从人口学特征、时间分布和地域差异三方面探讨KD在甘肃地区的流行病学特征,以期为西部地区KD的管理和预防提供科学依据。方法选取2012—2019年兰州大学第二医院收治的581例KD患儿为研究对象,根据入选患儿1个月内CAL发生情况将其分为KD合并CAL组(CAL组)和无CAL组(NCAL组),根据发病年龄划分为≤1岁、>1~3岁、>3~6岁和>6岁4个年龄段。采用统一的调查表收集一般资料(年龄、性别、民族、发病时间等)、冠状动脉彩超结果。结果(1)人口学特征:581例KD患儿的中位发病年龄为1.9(1.2,3.2)岁,男∶女为1.9∶1,男性患儿在KD人群中的发病比例随年龄的增长呈下降趋势(χ^(2)趋势=5.100,P<0.05)。(2)时间分布:不同年份间KD病例数总体呈上升趋势(χ^(2)趋势=122.348,P<0.001);各季节患儿分布情况比较,差异有统计学意义(χ^(2)=12.418,P=0.006);春季患儿占比与年龄段呈负相关(r_(s)=-1,P<0.001),而秋季患儿占比与年龄段呈正相关(r_(s)=1,P<0.001)。(3)地域差异:结合甘肃地理位置、自然条件和区域经济社会发展现状,将甘肃省划分为河西、陇中、陇东、陇东南、民族五大区域;依据城镇居民日常生活开支、职工平均工资和社会经济发展水平等将甘肃省按发达程度由高到低划分为四类地区。陇中(χ^(2)趋势=86.011,P<0.001)、陇东南(χ^(2)趋势=23.848,P<0.001)和民族区域的KD病例数(χ^(2)趋势=17.463,P<0.001)均逐年增加;一类(χ^(2)趋势=54.551,P<0.001)、二类(χ^(2)趋势=20.586,P<0.001)、三类(χ^(2)趋势=14.844,P<0.001)和四类地区的KD病例数(χ^(2)趋势=36.013,P<0.001)均逐年增加。(4)影响因素:不同年份间合并CAL(χ^(2)趋势=95.041,P<0.001)和NCAL的KD病例数(χ^(2)趋势=38.719,P<0.001)均呈上升趋势,尤以CAL组为著(χ^(2)趋势=9.502,P<0.05);多因素Logistic回归分析结果显示,年龄〔OR=3.011,95%CI(1.313,6.907)〕、性别〔OR=1.634,95%CI(1.137,2.349)〕和四类地区〔OR=1.772,95%CI(1.172,2.679)〕是KD合并CAL的影响因素。结论甘肃地区KD患病人数逐年增加,以CAL组KD患儿的增长为著,疾病负担严重,经济欠发达地区尤为明显,为降低KD及其并发症发生率,需要提高公众对疾病严重性的认识、在夏季对男性婴幼儿适当加大防治力度(尝试对KD高危人群提前干预,如免疫调节)、建立健全KD随访机制、加强基层医生培训、开展多中心研究并持续监测KD的流行病学特征以获取与最佳预防策略、早期诊断、治疗时机和治疗选择相关的重要信息。

关键词：川崎病黏膜皮肤淋巴结综合征流行病学研究冠状动脉疾病疾病特征

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学习迁移理论指导手术室护理教学的应用研究

现代医院 2011年第9期11卷 112-113页

作者：邓海梅姚晓芬文珠仁广东省农垦中心医院广东湛江524002

目的探讨学习迁移理论指导在手术室护理教学中的应用效果,以提高手术室护理教学水平和护生学习能力。方法采用等组实验研究法,将160名护生分为实验组和对照组。对照组运用传统护理教学,实验组采用促进学习迁移的教学内容、过程、方法,... 详细信息

目的探讨学习迁移理论指导在手术室护理教学中的应用效果,以提高手术室护理教学水平和护生学习能力。方法采用等组实验研究法,将160名护生分为实验组和对照组。对照组运用传统护理教学,实验组采用促进学习迁移的教学内容、过程、方法,进行一学年的临床护理教学,对结果用SPSS检验。结果两组护生的平时操行成绩、专科理论成绩、护理操作成绩比较,差异有显著性意义(p<0.01)。结论学习迁移理论指导手术室护理教学,能提高护生的学习效果,培养护生的主动学习和实践能力。

关键词：学习迁移理论指导手术室护理教学护生

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Autophagy-targeting modulation to promote peripheral nerve regeneration

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Neural Regeneration Research 2025年第7期20卷 1864-1882页

作者： Yan Chen Hongxia deng Nannan Zhang Department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityChengduSichuan ProvinceChina Key Laboratory of Birth Defects and Women and Children’s Diseases Ministry of EducationSichuan UniversityChengduSichuan ProvinceChina Laboratory of Reproductive Endocrinology and Reproductive Regulation Sichuan UniversityChengduSichuan ProvinceChina National Center for Birth Defect Monitoring West China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina

Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular *** studies have focused on factors that stimulate axonal outgrowth and myelin ***,recent studies have highlighted the pivotal role of autophagy in peripheral nerve regeneration,particularly in the context of traumatic ***,autophagy-targeting modulation has emerged as a promising therapeutic approach to enhancing peripheral nerve *** current understanding suggests that activating autophagy facilitates the rapid clearance of damaged axons and myelin sheaths,thereby enhancing neuronal survival and mitigating injury-induced oxidative stress and *** actions collectively contribute to creating a favorable microenvironment for structural and functional nerve regeneration.A range of autophagyinducing drugs and interventions have demonstrated beneficial effects in alleviating peripheral neuropathy and promoting nerve regeneration in preclinical models of traumatic peripheral nerve *** review delves into the regulation of autophagy in cell types involved in peripheral nerve regeneration,summarizing the potential drugs and interventions that can be harnessed to promote this *** hope that our review will offer novel insights and perspectives on the exploitation of autophagy pathways in the treatment of peripheral nerve injuries and neuropathies.

关键词： autophagy autophagy related genes Charcot–Marie–Tooth diseases diabetic peripheral neuropathy metformin myelination peripheral nerve injury Schwann cells sciatic nerve Wallerian degeneration

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辨证分型联合针灸治疗原发性高血压

实用中医内科杂志 2015年第5期29卷 75-76页

作者：陈德龙邓海媚段文俊广州中医药大学第三临床医学院 2010级中医骨伤方向广州510405

高血压属"头痛""眩晕"范畴,中医药辨证分型防治具有独特优势:肝阳上亢镇肝熄风汤配针灸,痰瘀阻络半夏白术天麻汤合通窍活血汤配针灸,气血亏虚归脾汤合补中益气汤配针灸,阴阳两虚左归丸或右归丸配针灸,均能获满意疗效。

关键词：原发性高血压辨证分型镇肝熄风汤半夏白术天麻汤通窍活血汤归脾汤补中益气汤左归丸右归丸针灸中医药治疗

前列腺癌中CD147、MMP-2 mRNA表达与临床分期、病理学分级的关系

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分子诊断与治疗杂志 2021年第5期13卷 824-827页

作者：吴狄邓海媚姚睿智陈铭广州中医药大学第一临床医学院泌尿外科广东广州510405 广州中医药大学第一附属医院泌尿外科广东广州510405

目的分析前列腺癌病灶组织中细胞外基质金属蛋白酶诱导因子CD147、基质金属蛋白酶(MMP)-2(MMP-2)mRNA表达与临床分期、病理学分级的关系。方法选取2015年4月至2018年12月本院收治的前列腺癌患者58例及同期行手术治疗的前列腺增生患者50... 详细信息

目的分析前列腺癌病灶组织中细胞外基质金属蛋白酶诱导因子CD147、基质金属蛋白酶(MMP)-2(MMP-2)mRNA表达与临床分期、病理学分级的关系。方法选取2015年4月至2018年12月本院收治的前列腺癌患者58例及同期行手术治疗的前列腺增生患者50例为研究对象,取前列腺癌患者病灶组织、癌旁组织及前列腺增生患者的组织标本,以原位杂交法测定各组织中CD147 mRNA表达水平,采用逆转录-聚合酶链反应(RT-PCR)测定MMP-2 mRNA,并评估CD147 mRNA表达与临床分期、病理学分级等的关系。结果前列腺癌病灶组织中CD147 mRNA阳性率及MMP-2表达水平高于前列腺癌癌旁组织、前列腺增生组织(P<0.05),前列腺癌癌旁组织CD147 mRNA阳性率及MMP-2表达水平也高于前列腺增生组织(P<0.05);前列腺癌患者中,临床分期T3~T4期、病理学分级≥5级、淋巴结转移N1期、远处转移M1期者的CD147 mRNA阳性率、MMP-2 mRNA表达水平高于临床分期T1~T2期、病理学分级2~4级、淋巴结转移N0期、远处转移M0期者,差异有统计学意义(P<0.05)。结论检测CD147、MMP-2 mRNA的表达对评估肿瘤恶性程度与生物学行为、预后有积极意义。

关键词：前列腺癌前列腺增生 CD147 mRNA MMP-2 mRNA

Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury:state of the art and future perspectives

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Neural Regeneration Research 2025年第11期20卷 3151-3171页

作者： Fatima Aldali Chunchu deng Mingbo Nie Hong Chen Department of Rehabilitation Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Orthopedics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

“Peripheral nerve injury”refers to damage or trauma affecting nerves outside the brain and spinal *** nerve injury results in movements or sensation impairments,and represents a serious public health *** severed peripheral nerves have been effectively joined and various therapies have been offered,recovery of sensory or motor functions remains limited,and efficacious therapies for complete repair of a nerve injury remain *** emerging field of mesenchymal stem cells and their exosome-based therapies hold promise for enhancing nerve regeneration and *** stem cells,as large living cells responsive to the environment,secrete various factors and *** latter are nano-sized extracellular vesicles containing bioactive molecules such as proteins,microRNA,and messenger RNA derived from parent mesenchymal stem *** have pivotal roles in cell-to-cell communication and nervous tissue function,offering solutions to changes associated with cell-based *** ongoing investigations,mesenchymal stem cells and mesenchymal stem cell-derived exosome-based therapies are in the exploratory stage.A comprehensive review of the latest preclinical experiments and clinical trials is essential for deep understanding of therapeutic strategies and for facilitating clinical *** review initially explores current investigations of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in peripheral nerve injury,exploring the underlying ***,it provides an overview of the current status of mesenchymal stem cell and exosomebased therapies in clinical trials,followed by a comparative analysis of therapies utilizing mesenchymal stem cells and ***,the review addresses the limitations and challenges associated with use of mesenchymal stem cell-derived exosomes,offering potential solutions and guiding future directions.

关键词： clinical trials exosome extracellular vesicles mesenchymal stem cells nerve regeneration peripheral nerve injury pre-clinical experiments

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崔学教治疗肾精亏损型弱精子症用药规律研究

中国中医药信息杂志 2019年第3期26卷 103-107页

作者：邓海媚姚睿智陈铭崔学教广州中医药大学第一临床医学院广东广州510405 广州中医药大学第一附属医院广东广州510405

目的分析崔学教教授治疗肾精亏损型弱精子症的用药特点,探讨其用药规律。方法收集2017年6月1日-2017年11月30日崔教授于广州中医药大学第一附属医院外科(男科)门诊诊治的肾精亏损型弱精子症病案数据。运用SPSS19.0统计软件,采用频数分... 详细信息

目的分析崔学教教授治疗肾精亏损型弱精子症的用药特点,探讨其用药规律。方法收集2017年6月1日-2017年11月30日崔教授于广州中医药大学第一附属医院外科(男科)门诊诊治的肾精亏损型弱精子症病案数据。运用SPSS19.0统计软件,采用频数分析、因子分析、聚类分析等统计方法进行数据挖掘。结果纳入病例247例、328诊次,剔除未使用中药91诊次,最终纳入处方237首,涉及药物75味,共计3071次。高频药物前5位是菟丝子(236次)、桑葚(236次)、覆盆子(226次)、淫羊藿(208次)、巴戟天(198次)。药物药性以平、温性,甘、苦味为主;主要归肝、肾经;多为补益之品(补阳药、补阴药、补气药)。挖掘得到9个公因子,均呈现出补益肾阳、健脾益气、补益气血等治法特点;聚类分析发现五子衍宗丸这一基础方。结论崔教授治疗肾精亏损型弱精子症用药规律体现了其以益肾为主的治疗原则,根据辨证配合使用收敛药、清热药等,补中有清、阴阳调和、标本兼治。

关键词：弱精子症肾精亏损型崔学教名医经验用药规律数据挖掘