检索结果-南通市图书馆

Sound event localization and detection based on deep learning

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2024年第2期35卷 294-301页

作者： zhao Dada DING Kai QI Xiaogang CHEN Yu FENG hailin School of Mathematics and Statistics Xidian UniversityXi’an 710071China Science and Technology on Near-Surface Detection Laboratory Wuxi 214035China

Acoustic source localization(ASL)and sound event detection(SED)are two widely pursued independent research *** recent years,in order to achieve a more complete spatial and temporal representation of sound field,sound event localization and detection(SELD)has become a very active research *** paper presents a deep learning-based multioverlapping sound event localization and detection algorithm in three-dimensional ***-Mel spectrum and generalized cross-correlation spectrum are joined together in channel dimension as input *** features are classified and regressed in parallel after training by a neural network to obtain sound recognition and localization results *** channel attention mechanism is also introduced in the network to selectively enhance the features containing essential information and suppress the useless ***,a thourough comparison confirms the efficiency and effectiveness of the proposed SELD *** experiments show that the proposed algorithm is robust to reverberation and environment and can achieve higher recognition and localization accuracy compared with the baseline method.

关键词： sound event localization and detection(SELD) deep learning convolutional recursive neural network(CRNN) channel attention mechanism

FAR3d程序对EAST上阿尔芬不稳定性识别过程中的应用

在线全文

学校读者我要写书评

暂无评论

原子能科学技术 2024年第1期58卷 14-22页

作者：王曦辉黄娟赵海林 JVarela 付静孙延旭史唱王书松中国科学院合肥物质科学研究院安徽合肥230031 中国科学技术大学安徽合肥230026 Universidad CarlosⅢde Madrid 28911 LeganesMadridSpain

为更好理解EAST实验中的等离子体不稳定性现象,文章从实验和模拟两个角度,对EAST中高βN放电区间的阿尔芬不稳定性现象进行了分析。在实验上,本文使用高频磁探针和电子回旋辐射诊断对不稳定性的频率、位置、环向模数进行判断。在模拟上... 详细信息

为更好理解EAST实验中的等离子体不稳定性现象,文章从实验和模拟两个角度,对EAST中高βN放电区间的阿尔芬不稳定性现象进行了分析。在实验上,本文使用高频磁探针和电子回旋辐射诊断对不稳定性的频率、位置、环向模数进行判断。在模拟上首次应用了FAR3d程序,识别了在ρ=0.45、频率为87 kHz的主导模式TAE(toroidicity-induced Alfven eigenmode),以及ρ=0.55、频率为62 kHz的次主导模式EPM(energetic particle mode),环向模数均为2,与实验中的测量结果对比在误差范围内基本一致,自洽地识别了不稳定性的类型并且得到了位置与频率信息。在此基础上,对有限拉莫轨道(finite Larmor radius, FLR)效应进行评估。模拟结果显示,在EAST高βN放电区间,FLR效应对识别低环向模数n的不稳定性模式的影响较小。在该放电的模式的识别过程中可关闭FLR以加速计算。FAR3d程序高效的计算能力和精准的模拟结果,可为后续EAST的实验提供指导。

关键词： FAR3d 阿尔芬本征模 EAST 快离子

维普期刊数据库博看期刊

低合金高强度钢焊接热影响区性能研究现状及改善措施

在线全文

学校读者我要写书评

暂无评论

焊管 2024年第6期47卷 7-16页

作者：甘正红赵海林李学达孙宪进张坤鹏江苏德创制管有限公司江苏兴化225700 南通振华重型装备制造有限公司江苏南通226000 中国石油大学(华东)材料科学与工程学院山东青岛266580 江阴兴澄特种钢铁有限公司江苏江阴214429 番禺珠江钢管(连云港)有限公司江苏连云港222006

低合金高强度钢焊接热影响区各区域因经历了不同的焊接热循环过程,组织发生显著改变,从而引起性能恶化,导致焊接热影响区成为焊接接头最薄弱的区域。针对低合金高强钢焊接热影响区性能的硬化、脆化和软化以及冷裂纹敏感性差异较大等问题... 详细信息

低合金高强度钢焊接热影响区各区域因经历了不同的焊接热循环过程,组织发生显著改变,从而引起性能恶化,导致焊接热影响区成为焊接接头最薄弱的区域。针对低合金高强钢焊接热影响区性能的硬化、脆化和软化以及冷裂纹敏感性差异较大等问题,分析总结了影响热影响区性能变化的关键因素,包括焊接热循环、焊接工艺条件、母材的化学成分和原始组织状态等,提出采用焊接热模拟技术、合理的母材成分设计、原始组织状态、焊接工艺参数优化等措施,以改善和提高焊接热影响区综合性能。

关键词：低合金高强钢热影响区焊接工艺

Dynamic performance of a C/C composite finger seal in a tilting mode

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2017年第4期30卷 1603-1614页

作者： hailin zhao Guoding CHEN Li'na WANG Hua SU Fei LU School of Mechanical Engineering Northwestern Polytechnical University

The complex operating state of aeroengines has an impact on the performance of finger seals. However, little work has been focused on the issue and the dynamic performance of finger seals is also rarely studied. Therefore, a distributed mass equivalent model considering working conditions is proposed in this paper for solving the existing problems. The effects of the fiber bundle density and the preparation direction of the fiber bundle of a C/C composite on the dynamic performance of a finger seal are investigated in rotor tilt based on the proposed model. The difference between the C/C composite finger seal performances under the rotor precession and nutation tilt cases is also investigated. The results show that the fiber bundle density and the preparation direction of the fiber bundle have an influence on the dynamic performance of the finger seal as rotor tilt is considered, and the dynamic performance of the finger seal is different in the two kinds of tilting modes. In addition, a novel method for design of finger seals is presented based on the contact pressure between finger boots and the rotor. Finger seals with good leakage rates and low wear can be acquired in this method.

关键词： Aero-engine C/C composite Dynamic performance Finger seal Nutation tilt Precession tilt

New Frontiers on Intracellular cGAS Activation:Molecular Mechanisms,Cellular Signaling,and Therapeutic Strategies

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第4期40卷 632-645页

作者： SONG Xingrui LING Xiaoting LIU Hailong zhao Qiang LI Xiangjun LAI Weiyi WANG hailin State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing10085P.R.China School of Chemical Sciences University of Chinese Academy of SciencesBeijing101408P.R.China

Cyclic GMP-AMP(cGAMP)synthase(cGAS)plays a pivotal role in the innate immune *** the primary DNA sensor in cells,cGAS binds to dsDNA in the cytoplasm and forms cGAS-DNA liquid-liquid phase separation(LLPS)and activates its catalytic *** activation triggers the cGAS-stimulator of interferon genes(STING)signaling pathway,establishing an efficient system for pathogen *** pathogen surveillance,cGAS performs a diverse range of roles,involved in inflammatory response,metabolic homeostasis,DNA damage repair,and cell *** biological functions regulate cellular physiological homeostasis and influence the occurrence and development of *** review provides an overview of the structure,localization,and intracellular biological functions of the cGAS-STING signaling pathway and cGAS-DNA ***,we discuss their contribution to the development of tumors,autoimmune diseases,and inflammatory diseases and highlight the innovative strategies in modulating cGAS activity,either through activation or inhibition,as a promising therapeutic approach.

关键词： Cyclic GMP-AMP(cGAMP)synthase(cGAS)-stimulator of interferon genes(cGAS-STING) Liquid-liquid phase separation(LLPS) Biological function Disease

非典型脑膜瘤显微手术治疗后复发的影响因素分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华生物医学工程杂志 2024年第1期30卷 45-50页

作者：罗冬冬罗爱萍姚雪峰胡骕赵海林李丹李佩恒叶淦伟彭彪广州医科大学附属肿瘤医院神经外科广州510095 广州医科大学附属肿瘤医院放射科广州510095 广州医科大学研究生学院广州510095

目的探讨非典型脑膜瘤(AMs)患者术后肿瘤复发的相关影响因素。方法回顾性分析广州医科大学附属肿瘤医院61例AMs患者的临床资料及随访资料,其中男31例,女30例,中位年龄55岁,均行显微手术切除。术后行三维适形放射治疗(3D-CRT)或放疗联合... 详细信息

目的探讨非典型脑膜瘤(AMs)患者术后肿瘤复发的相关影响因素。方法回顾性分析广州医科大学附属肿瘤医院61例AMs患者的临床资料及随访资料,其中男31例,女30例,中位年龄55岁,均行显微手术切除。术后行三维适形放射治疗(3D-CRT)或放疗联合替莫唑胺化疗,其中放疗组43例,无放疗组18例。采用Kaplam-Meier进行生存分析,Log-rank进行差异性检验,多因素Cox回归分析评估肿瘤复发的相关因素。结果61例AMs患者随访6~162月,复发28例,死亡9例,中位无进展生存时间(PFS)48个月,5年PFS 41.0%,5年总生存时间(OS)54.1%。单因素分析显示,肿瘤形状、瘤周脑水肿、脑侵袭、静脉窦侵袭、肿瘤切除程度和增殖指数(Ki67)≥10%与肿瘤术后复发相关(均P0.05)。多因素分析显示,脑侵袭、SimpsonⅡ-Ⅳ切除和Ki67≥10%的AMs患者术后复发的风险增加(均P<0.05)。结论AMs治疗以手术切除为主,术后放疗或放疗联合替莫唑胺化疗不能改善患者的PFS。脑侵袭、肿瘤手术切除程度和Ki67≥10%是肿瘤复发独立的影响因素。

关键词：非典型脑膜瘤预后疗效无进展生存时间

The effect of corporate culture on firm performance:Evidence from China

在线全文

学校读者我要写书评

暂无评论

China Journal of Accounting Research 2018年第1期11卷 1-19页

作者： hailin zhao Haimeng Teng Qiang Wu School of Accounting Nanjing University of Finance & Economics Lally School of Management Rensselaer Polytechnic Institute

This study examines whether corporate culture promotion affects firm performance in China in terms of firm market value, firm financial performance and innovation output. We find consistent evidence that corporate culture promotion is negatively related to firm market value, positively related to innovation output and not significantly related to firm financial performance. In addition,the negative effect of corporate culture promotion on firm market value is driven by small firms and firms located in less developed provinces. Furthermore,we find that some specific corporate culture promotions, such as innovation culture promotion and integrity culture promotion, are not related to firm value or financial performance. However, innovation culture promotion is positively associated with innovation output.

关键词： Corporate culture promotion Firm performance China

Epithelial-mesenchymal transition in organ fibrosis development:current understanding and treatment strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Burns & Trauma 2022年第1期10卷 598-617页

作者： Lexin Liu Qizhe Sun Frank Davis Jianhua Mao hailin zhao Daqing Ma Division of Anaesthetics Pain Medicine and Intensive CareDepartment of Surgery and CancerFaculty of MedicineImperial College LondonChelsea andWestminster HospitalLondonSW109NHUK Department of Nephrology and Urology Pediatric Urolith CenterThe Children’s Hospital of Zhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouZhejiang Province310003China Department of Nephrology The Children Hospital of Zhejiang UniversitySchool of MedicineHangzhouZhejiang Province310003China

Organ fibrosis is a process in which cellular homeostasis is disrupted and extracellular matrix is excessively *** can lead to vital organ failure and there are no effective treatments *** epithelial-mesenchymal transition(EMT)may be one of the key cellular mechanisms,the underlying mechanisms of fibrosis remain largely *** is a cell phenotypic process in which epithelial cells lose their cell-to-cell adhesion and polarization,after which they acquire mesenchymal features such as infiltration and migration *** injurious stimulation in different organs,EMT can be triggered by multiple signaling pathways and is also regulated by epigenetic *** narrative review summarizes the current understanding of the underlying mechanisms of EMT in fibrogenesis and discusses potential strategies for attenuating EMT to prevent and/or inhibit *** better understanding the role of EMT in fibrosis development,targeting EMT and beyond in developing therapeutics to tackle fibrosis is challenging but likely feasible.

关键词： EMT Fibrosis TGF-β Smad HDAC inhibitors TGF-βantibody Organ fibrosis Senescence Extracellular matrix

CircMYBL2 facilitates hepatocellular carcinoma progression by regulating E2F1 expression

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第6期32卷 1129-1139页

作者： JUNZHE YI BINBIN LI XIAOMIN YIN LINGRUI LIU CAILU SONG YING zhao MANBO CAI hailin TANG DONG CHEN NING LYU State Key Laboratory of Oncology in South China Guangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou510060China Department of Medical Oncology The Third People’s Hospital of YongzhouYongzhou425000China Department of Radiotherapy The First Affiliated HospitalHengyang Medical SchoolUniversity of South ChinaHengyang421001China Center of Hepato-Pancreato-Biliary Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhou510080China

Circular RNAs(circRNAs)have been recognized as pivotal regulators in tumorigenesis,yet the biological functions as well as molecular mechanisms of the majority of circRNAs in hepatocellular carcinoma(HCC)remain *** sought to unveil the expression profile and biological role of circMYBL2 in *** microarray analyses were conducted to probe the expression profile of circMYBL2 in HCC cells,and qRT‒PCR analysis was then performed in HCC cell lines and tissues,revealing significant upregulation of *** experiments were conducted to evaluate the biological function of circMYBL2 in HCC ***,bioinformatics analysis,qRT‒PCR analysis,luciferase reporter assays,and western blot analysis were employed to investigate the interplay among circMYBL2,miR-1205,and ***2 was found to exhibit marked upregulation in tumor tissues as well as HCC cell *** expression of circMYBL2 increased the proliferation and migration of HCC cells,whereas circMYBL2 knockdown elicited contrasting ***,our results indicated that circMYBL2 promoted E2F1 expression and facilitated HCC progression by sponging *** findings revealed that circMYBL2 contributed to HCC progression through the circMYBL2/miR-1205/E2F1 axis,suggesting the potential of circMYBL2 as a novel target for HCC treatment or a prognostic biomarker for HCC.

关键词： Circular RNAs circMYBL2 miR-1205 E2F1 Hepatocellular carcinoma