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Improving Network Availability through Optimized Multipath Routing and Incremental Deployment Strategies

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Computers, Materials & Continua 2024年第7期80卷 427-448页

作者： Wei Zhang haijun Geng Computer Application Teaching and Research Section China University of Labor RelationsBeijing100048China School of Automation and Software Engineering Shanxi UniversityTaiyuan030006China

Currently,distributed routing protocols are constrained by offering a single path between any pair of nodes,thereby limiting the potential throughput and overall network *** approach not only restricts the flow of data but also makes the network susceptible to failures in case the primary path is *** contrast,routing protocols that leverage multiple paths within the network offer a more resilient and efficient *** routing,as a fundamental concept,surpasses the limitations of traditional shortest path first *** not only redirects traffic to unused resources,effectively mitigating network congestion,but also ensures load balancing across the *** optimization significantly improves network utilization and boosts the overall performance,making it a widely recognized efficient method for enhancing network *** further strengthen network resilience against failures,we introduce a routing scheme known as Multiple Nodes with at least Two Choices(MNTC).This innovative approach aims to significantly enhance network availability by providing each node with at least two routing *** doing so,it not only reduces the dependency on a single path but also creates redundant paths that can be utilized in case of failures,thereby enhancing the overall resilience of the *** ensure the optimal placement of nodes,we propose three incremental deployment *** algorithms carefully select the most suitable set of nodes for deployment,taking into account various factors such as node connectivity,traffic patterns,and network *** deployingMNTCon a carefully chosen set of nodes,we can significantly enhance network reliability without the need for a complete overhaul of the existing *** have conducted extensive evaluations of MNTC in diverse topological spaces,demonstrating its effectiveness in maintaining high network availability with minimal path *** results are impressive,sh

关键词： Multipath routing network availability incremental deployment schemes genetic algorithm

Unlocking T cell exhaustion:Insights and implications for CAR-T cell therapy

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3416-3431页

作者： Dian Xiong haijun Yu Zhi-Jun Sun State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyFrontier Science Center for Immunology and MetabolismTaikang Center for Life and Medical ScienceWuhan UniversityWuhan 430079China Department of Radiation and Medical Oncology Hubei Province Cancer Clinical Study CenterHubei Key Laboratory of Tumor Biological BehaviorsZhongnan Hospital of Wuhan UniversityWuhan 430071China

Chimeric antigen receptor T(CAR-T)cell therapy as a form of adoptive cell therapy(ACT)has shown significant promise in cancer treatment,demonstrated by the FDA-approved CAR-T cell therapies targeting CD19 or B cell maturation antigen(BCMA)for hematological malignancies,albeit with moderate outcomes in solid ***,despite these advancements,the efficacy of CAR-T therapy is often compromised by T cell exhaustion,a phenomenon that impedes the persistence and effector function of CAR-T cells,leading to a relapse rate of up to 75%in patients treated with CD19 or CD2. CAR-T cells for hematological *** to overcome CAR-T exhaustion employ state-of-the-art genomic engineering tools and single-cell sequencing *** this review,we provide a comprehensive understanding of the latest mechanistic insights into T cell exhaustion and their implications for the current efforts to optimize CAR-T cell *** insights,combined with lessons learned from benchmarking CAR-T based products in recent clinical trials,aim to address the challenges posed by T cell exhaustion,potentially setting the stage for the development of tailored next-generation approaches to cancer treatment.

关键词： Cancer immunotherapy CAR-T therapy T cell exhaustion Tumor immune microenvironment Spatial immune contexture Single-cell technologies CAR-T engineering Combination therapy

Sm^(2.)ions boost ammonia electrooxidation reaction on samarium oxide anode for hydrogen generation in non-aqueous electrolyte

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Nano Research 2024年第7期17卷 5856-5862页

作者： Xingyu Liu Xue Yang Han Sun Zekai Yang haijun Chen Tianjin Key Laboratory of Optoelectronic Thin Film Devices and Technology College of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China

Ammonia has garnered recognition as a zero-carbon fuel due to its high-density hydrogen storage capacity and its convenience for storage and *** address the challenges associated with the direct usage of ammonia,the development of NH_(3)-to-H_(2.conversion technologies has emerged as a promising and effective ***,we present for the first time that crystallized Sm_(2.O_(3−x)electrodes demonstrate high and stable electrocatalytic activities,including N_(2.evolution rate and Faradaic efficiency,for ammonia electrolysis in a non-aqueous *** was observed that Sm^(2.)ions in samarium oxide play an indispensable role in the ammonia electrooxidation reaction on the ***,the mechanism of ammonia electrooxidation has also been elucidated,laying the foundation for a better understanding of the relationship between local structure and electrochemical properties in order to facilitate research on Pt-free electrocatalysts for the electrolysis of ammonia into H_(2..

关键词： NH_(3)-to-N_(2.conversion ammonia electrooxidation reaction ammonia electrolysis non-aqueous electrolyte samarium oxide

Genesis and Accumulation of Paleo-Oil Reservoir in Dabei Area,Kuqa Depression,Northwest China:Implications for Tight-Gas Accumulation

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Journal of Earth Science 2024年第2期35卷 655-665页

作者： Fujie Jiang Xiao Chen Pengwei Wang Xinghe Shao haijun Yang State Energy Center for Shale Oil Research and Development Beijing102206China National Key Laboratory of Oil and Gas Resources and Engineering Beijing102249China College of Geosciences China University of PetroleumBeijing102249China CNOOC International Ltd. Beijing100027China Research Institute of Petroleum Exploration&Production SINOPECBeijing100083China Research Institute of Petroleum Exploration and Development Tarim OilfieldPetroChinaKorla841000China

Paleo-oil reservoir is of great importance to understand hydrocarbon enrichment mechanism and hydrocarbon exploration potential,but is yet poorly investigated in Kuqa *** occurrence of the paleo-oil reservoir in Dabei area was proved by quantitative grain fluorescence(QGF)and fluid inclusion *** history of the paleo-oil reservoir was reconstructed through:(1)oil-source correlation;(2.time coupling of source rock maturation,porosity evolution and migration *** impact of paleo-oil reservoir on tight-gas accumulation was consequently *** suggest that considerable oil was accumulated in the K_(1)bs reservoir with paleo oil-water contact in Dabei 2.Well and Dabei 2.1 Well at 5800 and 6040 m,*** oil was primarily sourced from Triassic source rocks with Jurassic source rocks of secondary importance,which was at oil generation window(0.7%–1.1%Ro)during 9–6 and 7.5–5 Ma,*** occurrence of K_(1)bs tight reservoir(porosity2.)was about 2. Ma,while faults and associated fractures at Kelasue structural belt were developed approximately from 8 to 3.5 ***,the tight oil accumulation was formed during 8–5 *** paleo-oil reservoir in Dabei 1 gas field was destroyed by the evaporation fractionation in later stage.

关键词： Paleo-oil reservoir Dabei area Kuqa Depression Northwest China petroleum geology

Residual levels and health risk assessment of trace metals in Chinese resident diet

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Journal of Environmental Sciences 2024年第2期136卷 451-459页

作者： Yubing Dai Shuai Sun Rong Cao haijun Zhang Jiping Chen Ningbo Geng CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Shenyang Pharmaceutical University Shenyang 110016China University of Chinese Academy of Sciences Beijing 100049China

Large-scale metal contamination across the food web is an intractable problem due to increasing pollutant emissions,atmospheric transport,and dry and wet deposition of *** present study focus on several trace metals that are rarely studied but have special toxicity,including tin(Sn),antimony(Sb),gold(Au),hafnium(Hf),palladium(Pd),platinum(Pt),ruthenium(Ru),tellurium(Te)and iridium(Ir).We investigated trace metals residues and distribution characteristics,and further evaluated the potential health risks from major daily food intakes in 33 cities in ***,Sb,Ir,Hf,and Au were frequently detected in food samples with the concentrations ranged from ND(not detected)to 2..78μg/kg ww(wet weight).Eggs exhibited the highest residual level of all detected metals(13.70±14.70μg/kg ww in sum),while the lowest concentrations were observed in vegetables(0.53±0.17μg/kg ww in sum).Sn accounting for more than 50%of the total trace metals concentration in both terrestrial and aquatic animal origin *** terrestrial plant origin foods,Sn and Ir were the most abundant *** and Au were the most abundant elements in egg *** addition,Sb and Ir showed a clear trophic dilution effect in terrestrial environments,while in aquatic ecosystems,Sn,Hf,and Au exhibited obvious trophic amplification *** calculated average estimated daily intake(EDI)via food consumption in five regions of China was 0.09μg/(kg·day),implying the health risk of aforementioned elements was acceptable.

关键词： Trace metals Accumulation characteristics Dietary exposure Estimated daily intake(EDI)

Wireless semantic communication based on semantic matching multiple access and intent bias multiplexing

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The Journal of China Universities of Posts and Telecommunications 2024年第1期31卷 26-36页

作者： Ren Chao He Zongrui Sun Chen Li Haojin Zhang haijun University of Science and Technology Beijing Beijing 100083China Research and Development Center Sony(China)LimitedBeijing 100027China

This paper proposes a multi-access and multi-user semantic communication scheme based on semantic matching and intent deviation to address the increasing demand for wireless users and *** scheme enables flexible management of long frames,allowing each unit of bandwidth to support a higher number of *** leveraging semantic classification,different users can independently access the network through the transmission of long concatenated sequences without modifying the existing wireless communication *** overcome the potential disadvantage of incomplete semantic database matching leading to semantic intent misunderstanding,the scheme proposes using intent deviation as an *** allows different receivers to interpret the same semantic information differently,enabling multiplexing where one piece of information can serve multiple users with distinct *** results show that at a bit error rate(BER)of 0.1,it is possible to reduce the transmission by approximately 2. semantic basic units.

关键词： semantic communication multiple access multiplexing multimodal communication

Geometric quality evaluation of three-dimensional printable concrete using computational fluid dynamics

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 963-976页

作者： Weijiu CUI haijun SUN Jiangang ZHOU Sheng WANG Xinyu SHI Yaxin TAO Department of Civil Engineering Qingdao University of TechnologyQingdao 266000China Innovation Institute for Sustainable Maritime Architecture Research and Technology Qingdao University of TechnologyQingdao 266000China Intelligent Construction Lab Qingdao University of TechnologyQingdao 266000China Shandong Zhaojin Industrial Development Co. Ltd.Yantai 264000China Architectural Engineering Institute Weifang Engineering Vocational CollegeWeifang 261000China Qingjian Group Co. Ltd.Qingdao 266000China College of Architecture and Urban Planning Qingdao University of TechnologyQingdao 266000China Department of Structural Engineering and Building Materials Ghent UniversityGhent 9000Belgium Institute of Building Materials ETH ZurichZurich 8064Switzerland

The importance of geometrical control of three dimensional(3D)printable concrete without the support of formwork is widely *** this study,a numerical model based on computational fluid dynamics was developed to evaluate the geometrical quality of a 3D printed *** numerical results were compared,using image analysis,with physical cross-sectional sawn *** influence of printing parameters(printing speed,nozzle height,and nozzle diameter)and the rheological behavior of printed materials(yield stress),on the geometrical quality of one printed layer was *** addition,the yield zone of the printed layer was analyzed,giving insights on the critical factors for geometrical control in 3D concrete *** indicated that the developed model can precisely describe the extrusion process,as well as the cross-sectional quality.

关键词： digital fabrication 3D concrete printing geometric quality computational fluid dynamics printing parameters yield stress

Semitransparent organic solar cells with high light utilization efficiency and color rendering index

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Science China Chemistry 2024年第7期67卷 2248-2256页

作者： Ni Gao haijun Bin Shangrong Wu RenéA.J.Janssen Yongfang Li Laboratory of Advanced Optoelectronic Materials Suzhou Key Laboratory of Novel Semiconductor Materials and DevicesCollege of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Soochow UniversitySuzhou 215123China Molecular Materials and Nanosystems&Institute for Complex Molecular Systems Eindhoven University of TechnologyEindhoven 5600 MBthe Netherlands

Semitransparent organic solar cells(ST-OSCs)have garnered considerable attention as promising renewable energy technology for integrating photovoltaics into ***,there is a trade-off between power conversion efficiency(PCE)and average visible transmittance(AVT),which hinders the achievement of a high light utilization efficiency(LUE).In this study,we propose a valuable method to address this challenge by replacing the transparent top electrode,Ag,with a 2. nm layer of *** ST-OSCs based on the 2. nm Au electrode demonstrate superior exciton extraction,more efficient charge collection,and higher color-rendering index(CRI)due to their smoother surface,higher conductivity,and enhanced visible light transmittance,resulting in a significantly higher PCE of 13.67%and an enhanced AVT of 30.17%,contributing to a high LUE of 4.15%.Additionally,optically transparent dielectric layers,applied on the front and back sides of the ST-OSCs to further boost performance,delivered an impressive LUE of 4.93%,with PCE and AVT values reaching 14.44%and 34.12.,***,the champion ST-OSCs also exhibited a favorable CRI value of *** achievements represent the bestperforming ST-OSCs to date with both high LUE and CRI and hold significant implications for the prospective commercialization of ST-OSCs.

关键词： semitransparent organic solar cells power conversion efficiency average visible transmittance light utilization efficiency color-rendering index

Numerical investigation of friction-heating-pressurization and its control parameters in the shear band of high-speed landslides

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Journal of Mountain Science 2024年第10期21卷 3380-3395页

作者： ZHAO Nenghao CUI Shenghua LU haijun School of Civil Engineering and Architecture Wuhan Polytechnic UniversityWuhan 430023China State Key Laboratory of Geo-Hazard Prevention and Geo-Environment Protection Chengdu University of TechnologyChengdu 610059China

High-speed sliding often leads to catastrophic landslides,many of which,in the initial sliding phase before disintegration,experience a friction-induced thermal pressurization effect in the bottom shear band,accelerating the movement of the overlying sliding *** quantitatively investigate this complex multiphysical phenomenon,we established a set of equations that describe the variations in temperature and excess pore pressure within the shear band,as well as the conservation of momentum equation for the overlying sliding *** a simplified landslide model,we investigated the variations of temperature and excess pore pressure within the shear band and their impacts on the velocity of the overlying sliding *** this basis,we studied the impact of seven key parameters on the maximum temperature and excess pore pressure in the shear band,as well as the impact on the velocity of the overlying sliding *** simulation results of the standard model show that the temperature and excess pore pressure in the shear band are significantly higher than those in the adjacent areas,and reach the maximum values in the *** a few seconds after the start,the maximum excess pore pressure in the shear zone is close to the initial stress,and the shear strength loss rate exceeds 90%.The thermal pressurization mechanism significantly increases the velocity of the overlying sliding *** results of parameter sensitivity analysis show that the thermal expansion coefficient has the most significant impact on the temperature and excess pore pressure in the shear band,and the sliding surface dip angle has the most significant impact on the velocity of the overlying sliding *** results of this study are of great significance for clarifying the mechanism of thermal pressurization-induced high-speed sliding.

关键词： High-speed landslide Shear band Friction-heating-pressurization Numerical investigation