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Spreading Behavior and Hot Cracking Mechanism of Single Tracks in High Strength Al–Cu–Mg–Mn Alloy Fabricated by Laser Powder Bed Fusion

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Acta Metallurgica Sinica(English Letters) 2023年第9期36卷 1454-1464页

作者： Xiaojia Nie Ze Chen Yang Qi Hu Zhang haihong zhu College of Ship and Ocean Naval University of EngineeringWuhan430033China Department of Basic Courses Naval University of EngineeringWuhan430033China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan430074China School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan430074China

Laser powder bed fusion(LPBF)technology is a high-precision metal additive manufacturing(AM)*** to the high specific strength of high strength aluminum alloys,high strength aluminum alloys fabricated by LPBF have broad application prospects in the field of light ***,high strength aluminum alloys have high hot cracking *** this study,an analysis of the hot cracking susceptibility as a function of processing parameters is presented for single tracks of LPBF processed(LPBFed)high strength Al–Cu–Mg–Mn *** hot cracking in single tracks of LPBFed Al–Cu–Mg–Mn alloy is solidification cracking based on the experimental observations of *** Rosenthal simulations and spreading behavior of a single droplet,the critical scanning speed of single track with balling phenomenon was *** was found that when the laser power was 200 W,the scanning speed exceeded 440.1 mm/s,the droplet will not be able to spread completely,which is consistent with the experimental result of 500 mm/*** the calculation and analysis of the microstructure and the existence time of the molten pool,it was pointed out that the reduction in the liquid phase caused by the high scanning speed,the shortening of the solidification time and the high stress caused by the high-temperature gradient promoted the generation of hot *** summary,this work contains a practical guide to optimize processing parameters of LPBFed Al–Cu–Mg–Mn alloys,which provides a basis for fabricating thin walls and cubic samples without hot cracking.

关键词： Laser powder bed fusion High strength aluminum alloy Hot cracking Single track

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Spatiotemporal expression and application of urban residential solar rights based on CityGML-LADM

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International Journal of Digital Earth 2023年第1期16卷 2301-2321页

作者： Chengcheng Liu haihong zhu Lin Li Jianfang Ma Feng Li School of Resource and Environmental Sciences(SRES) Wuhan UniversityWuhanPeople's Republic of China

Property disputes are frequent occurrences in rapidly urbanizing *** the legal issues concerning building property rights,solar rights disputes are prevalent because text clauses on solar rights rely on diverse measurements or ***,previous studies on measuring solar rights addressed only the sunlight duration and neglected the daylight factor(daylighting coefficient),which is an integral component of solar ***,this study proposes a 3D spatiotemporal model for effectively measuring solar rights by taking both the sunlight duration and the daylight factor into *** model would be technologically valuable in avoiding or settling legal *** the specifications of the solar rights of building property in China as a case study,the proposed spatiotemporal model clarifies the complete solar rights of residential units and is implemented by integrating a geometric model from CityGML with a property model,namely,the Land Administration Domain Model(LADM).Three real typical cases are adopted to show the applicability and benefit of the 3D spatiotemporal model in resolving legal property disputes.

关键词： Solar rights Spatiotemporal expression CityGML LADM Legal disputes

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Interfacial characteristics and mechanical properties of additive manufacturing martensite stainless steel on the Cu-Cr alloy substrate by directed energy deposition

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Journal of Materials Science & Technology 2021年第31期90卷 121-132页

作者： Wenqi Zhang Hailong Liao Zhiheng Hu Shasha Zhang Baijin Chen Huanqing Yang Yun Wang haihong zhu Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Material Processing and Die&Mould Technology School of Material Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China XI’AN Space Engine Company Limited Xi’an710100China

Copper/steel is a typical bimetal functional material,combining the excellent electrical and thermal conductivity of copper alloy and the high strength and hardness of stainless *** has been recent interest in manufacturing copper/steel bimetal by directed energy deposition(DED)due to its layer-bylayer ***,cracks tend to form on the copper/steel interface because of the great difference in thermal expansion coefficient and crystal structure between copper and *** this work,interfacial characteristics and mechanical properties of the copper/steel bimetal were studied from one layer to *** laser power has a great influence on the Cu element distribution of the molten pool,affecting the crack formation dramatically on the solidification *** tend to form along columnar grain boundaries because of the Cu-rich liquid films and spherical particles in the ***-free and good metallurgical bonding copper/steel interface is formed at a scanning velocity of 800 mm/min and the laser power of 3000 *** ultimate tensile strength(UTS)and the break elongation(EL)of the vertically combined crack-free copper/steel bimetal are 238.2±4.4 MPa and 20.6±0.7%,*** fracture occurs on the copper side instead of the copper/steel interface,indicating that the bonding strength is higher than that of the Cu-Cr *** UTS of the horizontally combined crack-free copper/steel bimetal is 746.7±22.6 MPa,which is 200%higher than that of the Cu-Cr alloy *** microhardness is 398.6±5.4 HV at the steel side and is 235.3±64.1 HV at the interface,which is400%higher than that of the Cu-Cr alloy *** paper advances the understanding of the interfacial characteristics of heterogeneous materials and provides guidance and reference for the fabrication of multi-material components by DED.

关键词： Directed energy deposition Additive manufacturing Bimetal Interfacial characteristics Crack

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Focus on Dysregulated Adaptive Immunity in Chronic Hepatitis B:A Promising Direction for Immunotherapy

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Infectious Microbes & Diseases 2022年第1期4卷 7-12页

作者： Jiaming Zhou Chunhong Huang haihong zhu Zhi Chen State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesNational Medical Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang China

Hepatitis B virus(HBV)infection is a public health problem that endangers global health and is the leading cause for the occurrence and death due to hepatocellular *** nucleotide analogs are excellent in controlling virus replication,they have little effect on the production,stability,and transcription of covalently closed circular DNA(cccDNA)in infected ***,only a small fraction of patients with chronic hepatitis B are cured by interferon *** HBV infection,HBV-specific B cells and T cells are ***-specific T cells exert antiviral effects through cell lysis and non-cytolytic effector functions,reducing viral intermediates and *** addition,HBV-specific B cells produce antibodies that eliminate HBV-infected liver cells through antibody-dependent cell-mediated cytotoxicity of natural killer *** can also bind to the hepatitis B surface antigen on the surface of the virus particle,inducing antibody-dependent phagocytosis by Kupffer *** responses could be combined with immunotherapy based on antiviral therapy,which may achieve a complete cure for hepatitis ***,patients with chronic hepatitis B have immune dysfunctions,which challenges immunotherapy *** review focuses on advances in adaptive immunotherapy for chronic viral hepatitis B.

关键词： hepatitis B virus chronic hepatitis B antiviral therapy immunotherapy immune checkpoint inhibitor vaccine cell therapy

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The Knowledge on HCV:From the Discovery to the Elimination

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Infectious Microbes & Diseases 2022年第1期4卷 1-6页

作者： Jun Guan Yanli Ren Jing Wang haihong zhu State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina

From being described as“non-A,non-B”hepatitis in 1975 and being identified in 1989,to the emergence of direct-acting antiviral drugs(DAAs),knowledge on hepatitis C virus(HCV)has achieved a qualitative leap in recent *** more than 95%of HCV patients can be cured by DAAs,the high detection rate,high treatment cost,and relative high recurrence rate for some subtypes(eg,type 3b)make it still a public health problem *** to the widespread availability of DAAs,vaccine research has received relatively little *** purpose of this review is to look back to the discovery of the HCV,its life cycle,innate and adaptive immune responses,and the evolution of treatment options for HCV.

关键词： HCV discovery life cycle immune response therapy vaccination

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Laser stripping of fiber Bragg grating polymer coating using pulsed 10.6 μm TEA CO2 laser

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Frontiers of Optoelectronics 2010年第3期3卷 303-307页

作者： haihong zhu Wenjuan LEI Cheng DAI Zuhai CHENG Division of Laser Science and Technology Wuhan National Laboratory for Optoelectronics College of Optoelectronic Science and EngineeringHuazhong University of Science and Technology

Stripping the polymer coating is the first step for the fabrication of fiber Bragg grating（FBG）. The conventional stripping approaches are labor intensive and time consuming. Because of high precision and throughput, as well as non-contacting, laser stripping obtained more and more attention in recent years. This paper reports the primary experiments on laser stripping of polymer coating from FBG using pulsed transverse electric atmospheric（TEA） CO2laser with wavelength of 10.6 μm and pulse width of 2 μs. Using cylindrical lenses, the coating can be removed thoroughly at one time. The theoretical analysis and experimental investigations were carried out. The influence of laser fluence and pulse number on stripping quality has been *** electron microscopy（SEM）, optical microscope,and electrical balance were employed to detect the quality removal. The result shows that excellent quality removal is possible by using pulsed 10.6 μm TEA CO2laser.

关键词： 3a\10\23\90\hcm0000169691.html

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THE CHANGES OF IL-1β AND IL-6 LEVEL AT DIFFERENT ALTITUDE AND THEIR SIGNIFICANCE

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青海医学院学报 2006年第2期27卷 73-74,85页

作者： Jia Mian Geng Paili zhu haihong Wu Hongfu Dept. of Immunology Qinghai University Medical College Qinghai China

Objective To investigate the changes of the concentration of interkeukine β 1(IL-1β) and Interleukine 6(IL-6) in the serum of the people who live in the different altitude,and try to find the relation between the cytokines(CK) and the hypoxia adaptation and some diseases caused by *** Using enzyme linked immunoabsorbent assay(ELISA) to detect the level of the concentration of IL-1β and IL-6 in the *** The concentration of IL-1β showed significant increase in values(P<0.05) at ***-6 in same altitude showed obvious changes as well(P<0.05).Conclusion The results showed that the concentration of IL-1β and IL-6 have significant changes in the *** means that they may be involved in the process of the adaptation and some sickness because of hypoxia.

关键词：细胞活素 IL-1β IL-6 白细胞介素

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小比例尺地图面状水系名称注记自动配置研究

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武汉大学学报（信息科学版） 2007年第6期32卷 544-547页

作者：王琤李霖朱海红武汉大学资源与环境科学学院

在丰富面状水系的注记配置规则基础上,深入研究了其名称注记自动配置中两个关键算法,即要素主骨架线求取和注记配置方案的设计,并提出了基于单调链化简思想确定面状水系主骨架线的改进算法,在此基础上设计了面状水系名称注记自动配置方案。

关键词：面状水系名称注记自动配置主骨架线单调链

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融合建筑物所有权及其附属权利的LADM-BIM数据模型研究

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地球信息科学学报 2024年第5期26卷 1229-1242页

作者：刘承承朱海红李霖武汉大学资源与环境科学学院武汉430079

在居民物权意识不断增强的背景下,城市中涉及建筑物所有权、地役权和采光权的法律纠纷案例数量不断增加,对城市和谐社区的构建带来了不利影响,同时也消耗了大量社会资源。然而,现有研究一方面过多地侧重于这些权利的法律描述,另一方面... 详细信息

在居民物权意识不断增强的背景下,城市中涉及建筑物所有权、地役权和采光权的法律纠纷案例数量不断增加,对城市和谐社区的构建带来了不利影响,同时也消耗了大量社会资源。然而,现有研究一方面过多地侧重于这些权利的法律描述,另一方面则局限于仅利用三维技术构建所有权空间模型,缺乏对建筑物所具有的复杂所有权的空间结构及其附属权利(地役权和采光权)的深入的研究。本文深入分析了法律背景下建筑物所有权、地役权和采光权的三维建模的数据需求,通过扩展工业基础类(IFC),将土地管理领域模型(LADM)中的权利人包、空间单元包、权限管理包和测量与空间表达包映射到IFC标准中,实现了LADM和建筑物信息模型(BIM)的无缝集成,构建了一个三维数据模型。该模型考虑了建筑物所有权空间的复杂结构及其计算规则,对于地役权则特别考虑了水平和垂直方向上的三维实例化,采光权则考虑了相邻采光权和采光地役权及其参数的计算。LADM和BIM的整合使所提出的模型能够清晰呈现物理对象的空间特征,同时反映了建筑物的权利、限制和责任(RRR)的法律信息。为了验证模型的可行性和实用性,选取了真实的法律纠纷案例进行解析实验。结果表明,本文构建的模型可以区分所有权内部空间及其复杂结构,并能对地役权和采光权进行三维表达,同时包含了权属信息,为对法律空间的认知提供了更为明晰的理解,从而为解决相关纠纷提供可靠和坚实的技术方案。

关键词：建筑物所有权地役权采光权三维数据模型数据需求 LADM BIM/IFC 法律纠纷

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Impact of antitumor regimens on the outcomes of cancer patients with COVID-19:a pooled analysis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2021年第10期22卷 876-884页

作者： Haohua LU Yu SHI Kelie CHEN Zhi CHEN haihong zhu Yuequn NIU Dajing XIA Yihua WU Department of Toxicology of School of Public Health and Department of Gynecologic Oncology of Women’s Hospital School of MedicineZhejiang UniversityHangzhou 310058China The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases the First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Hangzhou 310003China National Clinical Research Center for Infectious Diseases Hangzhou 310003China

Since the outbreak of coronavirus disease 2019(COVID-19),which is caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)discovered in December 2019,the disease has emerged as a global pandemic(Shi et al.,2020;World Health Organization,2020).Several studies have shown a higher incidence of COVID-19,as well as related poor outcomes in patients with malignancies as compared with those without them(Liang et al.,2020;Tian et al.,2020).

关键词： patients regimen

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