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Fabricating high-performance sodium ion capacitors with P2-Na_(0.67)Co_(0.5)Mn_(0.5)O_2 and MOF-derived carbon

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Journal of Energy Chemistry 2019年第1期28卷 79-84页

作者： haichen gu Lingjun Kong Huijuan Cui Xianlong Zhou Zhaojun Xie Zhen Zhou School of Materials Science and Engineering National Institute for Advanced Materials Institute of New Energy Material Chemistry Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Nankai University

Sodium ion capacitors(SICs) have been considered as a kind of promising devices to achieve both high power and energy density. However, it is still a challenge to achieve high energy output at elevated power delivery due to the poor rate capability of battery-type electrode materials and the kinetic mismatch with capacitor-type electrode materials. In this work, to fabricate SICs, P2-Na_(0.67)Co_(0.5)Mn_(0.5)O_2(P2-NCM)was chosen as the battery-type cathode material, and a typical metal-organic framework(MOF) material,zeolitic imidazolate framework-8(ZIF-8) derived carbon(ZDC) was utilized as the capacitor-type anode material. Due to the kinetic match and high-rate performance of both electrodes, the ZDC//P2-NCM SICs exhibited an energy output of 18.8 Wh kg^(-1) at a high power delivery of 12.75 kW kg^(-1).

关键词： Energy density Power density P2-phase material Zeolitic imidazolate framework-8 Sodium ion capacitors

A unique hierarchical VOxCy/porous carbon derived from metalorganic frameworks for sodium storage

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A unique hierarchical VOxCy/porous carbon derived from metal...

第十四届固态化学与无机合成学术会议

作者： Lingjun Kong Chaopeng Wang haichen gu Xianhe Bu

Sodium-ion batteries(SIBs) is one of the most promising energy storage systems in replace of LIBs because of its relatively abundant resource. The radius of sodium ion(1.02 A) is much larger than that of lithium ion(0.76 A),and it leads many materials,which are suitable for LIBs,could not be used for anodes in *** a result,intensive efforts have been made to explore suitable materials for SIBs ***,it has been reported that metal-organic frameworks(MOFs) can be directly converted into various carbon-based functional materials via a pyrolysis process. However,it still remain challenge for the effective inheritance of the vital porosity and high-dispersed active sites from MOFs to the derived carbon ***,a vanadium compounds embedded in porous amorphous carbon material was prepared through facile pyrolysis of vanadium-based MOF(VM-p) The result reveals superior electrochemical performances of VM-1 for Na storage,associated with its unique nanotubes structure derived from the precursor as expected.

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基于数字化的道路勘测设计课程教学改革研究

建筑经济 2022年第S02期43卷 271-274页

作者：武保华黄艳梅顾海琛西南交通大学希望学院土木工程学院四川成都610000

本文分析土木工程专业道路勘测设计课程的现状和存在问题,从调整课程规划和课程教学大纲,整合教学内容融入数字化测量和数字化设计软件,改革教学手段建立数字化教学资源库,推进数字化实践教学和改革考核方式等方面提出基于现代数字化考... 详细信息

本文分析土木工程专业道路勘测设计课程的现状和存在问题,从调整课程规划和课程教学大纲,整合教学内容融入数字化测量和数字化设计软件,改革教学手段建立数字化教学资源库,推进数字化实践教学和改革考核方式等方面提出基于现代数字化考虑的勘测设计课程教学体系。并从提高工程测量中数字化的比重,采用项目驱动为主导的教学方法,以及加强道路勘测实训把软件运用和道路选线实际结合起来等方面,进行基于现代数字化的道路勘测设计课程教学设计,从现有教学评价上看,该项教学改革取得了一定的效果。

关键词：道路勘测设计数字化教学改革土木工程专业

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双束电子显微镜在锂离子电池研究中的应用

分析测试技术与仪器 2024年第5期30卷 286-294页

作者：何雨桐谷海辰孔令俊天津大学化工学院天津300072 北京新能源汽车股份有限公司北京100176

锂离子电池技术作为新能源储存领域重要的电池技术,具有广阔的发展前景.近年来,电极材料的开发和制备工艺的优化成为了锂离子电池技术的研究重点.双束电子显微镜又称聚焦离子束–扫描电子显微镜(focused ion beam-scanning electron mic... 详细信息

锂离子电池技术作为新能源储存领域重要的电池技术,具有广阔的发展前景.近年来,电极材料的开发和制备工艺的优化成为了锂离子电池技术的研究重点.双束电子显微镜又称聚焦离子束–扫描电子显微镜(focused ion beam-scanning electron microscope,FIB-SEM),是一种兼具微纳加工和显微成像功能的显微分析仪器,具有精确定点加工、高分辨扫描成像、适用多种类样品等优点,可为锂离子电池材料表征提供重要的技术支撑.对锂离子电池材料研究中FIB-SEM的应用场景进行了总结,归纳了FIB-SEM和其他仪器联用可实现的拓展功能.最后,对FIB-SEM在锂离子电池材料研究中的潜在应用进行了展望.

关键词：聚焦离子束扫描电子显微镜仪器联用锂离子电池失效分析

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai Xu Zhen gu Hua Yan Dingding Shen Xiaosong gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang Yuan Liang Yixue gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Brain-derived neurotrophic factor plays with TRiC:focus on synaptic dysfunction in Huntington’s disease

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Neural Regeneration Research 2025年第10期20卷 2919-2920页

作者： Yingli gu Kijung Sung Chengbiao Wu Department of Neurosciences University of California San DiegoLa JollaCAUSA

Brain-derived neurotrophic factor(BDNF)exerts pleiotropic effects on brain processes including psychiatric disorders,aging,neurodegeneration,and metabolic homeostasis.A simple PubMed search using the key word“BDNF,”to date,yields over 33,000 *** fundamental biology to potential therapeutic applications,BDNF has clearly garnered extensive and significant attention in the field of neurobiology research.

关键词： Huntington homeostasis therapeutic

From single to combinatorial therapies in spinal cord injuries for structural and functional restoration

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Neural Regeneration Research 2025年第3期20卷 660-670页

作者： Ernesto Doncel-Pérez Gabriel guízar-Sahagún Israel Grijalva-Otero Hospital Nacional de Parapléjicos de Toledo Servicio de Salud de Castilla La Mancha(SESCAM)ToledoSpain Medical Research Unit for Neurological Diseases UMAE Hospital de EspecialidadesCentro Médico Nacional Siglo XXIIMSSCiudad de MéxicoMéxico

Spinal cord injury results in paralysis, sensory disturbances, sphincter dysfunction, and multiple systemic secondary conditions, most arising from autonomic dysregulation. All this produces profound negative psychosocial implications for affected people, their families, and their communities;the financial costs can be challenging for their families and health institutions. Treatments aimed at restoring the spinal cord after spinal cord injury, which have been tested in animal models or clinical trials, generally seek to counteract one or more of the secondary mechanisms of injury to limit the extent of the initial damage. Most published works on structural/functional restoration in acute and chronic spinal cord injury stages use a single type of treatment: a drug or trophic factor, transplant of a cell type, and implantation of a biomaterial. Despite the significant benefits reported in animal models, when translating these successful therapeutic strategies to humans, the result in clinical trials has been considered of little relevance because the improvement, when present, is usually insufficient. Until now, most studies designed to promote neuroprotection or regeneration at different stages after spinal cord injury have used single treatments. Considering the occurrence of various secondary mechanisms of injury in the acute and sub-acute phases of spinal cord injury, it is reasonable to speculate that more than one therapeutic agent could be required to promote structural and functional restoration of the damaged spinal cord. Treatments that combine several therapeutic agents, targeting different mechanisms of injury, which, when used as a single therapy, have shown some benefits, allow us to assume that they will have synergistic beneficial effects. Thus, this narrative review article aims to summarize current trends in the use of strategies that combine therapeutic agents administered simultaneously or sequentially, seeking structural and functional restoratio

关键词： neural regeneration neuroprotection spinal cord injury repair spinal cord injury treatments structural restoration of spinal cord injury

Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

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Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu Xiang Renrui Niu Xiaodong He Wenqi Luo Wanguo Liu Rui gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury