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Muscular involvement of extranodal natural killer/T cell lymphoma misdiagnosed as polymyositis: A case report and review of literature

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World Journal of Clinical Cases 2020年第5期8卷 963-970页

作者： Li-Hui liu Qing Huang yun-hai liu Jie Yang Han Fu Lin Jin Department of Neurology Xiangya Hospital of Central South UniversityChangsha 410008Hunan ProvinceChina Department of Geriatrics Stroke Center Cerebrovascular disease clinical research center of Hunan provinceChangsha 410008Hunan ProvinceChina Department of Dermatology Xiangya Hospital of Central South UniversityChangsha 410008Hunan ProvinceChina

BACKGROUND Natural killer(NK)/T cell lymphoma is a rare and highly aggressive malignant tumor,and is a special form of non-Hodgkin's *** extranodal involvement is frequently found in tissues such as the skin,testicular and gastrointestinal tract etc,its presence in skeletal muscle has scarcely been reported in the *** SUMMARY We report a case of extranodal NK/T cell lymphoma with muscle swelling as the first clinical manifestation.A 42-year-old man,who initially presented with localized swelling in the double lower extremities,demonstrated gradual facial and eyelid swelling,and his imaging results showed multiple sites of muscle damage throughout the *** final pathological results suggested NK/T cell lymphoma,and immunohistochemistry showed CD20(-),CD3(+),CD30(+),CD56(-),EBER(+),Ki67(60%),TIA-1(+)and CD68(±)*** muscle swelling significantly improved after treatment with chemotherapy *** This disease is difficult to diagnose and highly invasive,and should be included in the differential diagnosis of unexplained muscle swelling.

关键词： Lymphoma Extranodal natural killer/T cell lymphoma Muscular Polymyositis Muscle swelling Case report

Single-site Baseline and Short-term Outcomes of Clinical Characteristics and Life Quality Evaluation of Chinese Wet Age-related Macular Degeneration Patients in Routine Clinical Practice

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Chinese Medical Journal 2015年第9期128卷 1154-1159页

作者： Li-Li Wang Wen-Jia liu hai-yun liu Xun Xu Department of Ophthalmology Shanghai First People@s Hospital Shanghai 200080 China

Background：Age-related macular degeneration （AMD） is the leading cause of irreversible vision loss among the older *** China,treatment of age-related ocular diseases is becoming a priority in eye care *** study was to investigate the clinical characteristics and quality of life of Chinese patients with wet AMD and current treatment types,to evaluate short-term gains in different treatments,and to investigate associations between visual function and vision-related quality of life （VRQoL）.Methods：A prospective,observational,noninterventional study was *** data were collected from patients with clinical diagnoses of wet AMD before clinical assessments at *** was measured with the Chinese version of the National Eye Institute Visual Function Questionnaire-25 （NEI VFQ-25）.Correlations of the NEI VFQ-25 subscale scores with best-corrected visual acuity （BCVA） and between-group differences were ***：A total of 80 wet AMD patients were enrolled,with the mean age of 68.40 *** one-quarter ofwetAMD patients received intravitreal （IVT） ranibizumab treatment,and 67％ of them were treated on apro re nata *** visual acuity of patients treated with IVT ranibizumab at month 3 after treatment was significantly increased,whereas patients treated with traditional Chinese medicine achieved no significant ***＇s α for the NEI VFQ-25 subscales ranged from 0.697 to *** subscale and overall composite scores were moderately correlated with the BCVA of the better-seeing *** differences in the overall NEI VFQ-25 scores and other subscales were observed between patients with BCVA in the better-seeing eye of less than 50 letters and the ***：Patients treated with IVT ranibizumab experienced better vision improvement at short-term *** Chinese version of the NEI VFQ-25 is a valid and reliable tool for assessing the VRQoL of Chinese wet AMD patients.

关键词： Chinese Version of National Eye Institute Visual Function Questionnaire-25 Ranibizumab Vision-related Quality of Life Wet Age-related Macular Degeneration

Pars plana vitrectomy for retinal detachment using perfluoro-n-octane as intraoperative tamponade:a multicenter,randomized,non-inferiority trial

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 82-91页

作者： Xin Shi Wei-Jun Wang Ying Fan hai-yun liu Hong Wang Yu-Hui Chen Ao Rong Zhi-Feng Wu Xun Xu Kun liu Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineNational Clinical Research Center for Eye DiseasesShanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghai 200085China Shanghai Jieshi Medical Technology Co.Ltd. Shanghai 201201China Department of Ophthalmology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Ophthalmology Wuxi No.2 People’s Hospital(Jiangnan University Medical CenterJUMC)Wuxi 214002Jiangsu ProvinceChina

AIM:To evaluate the efficacy and safety of perfluoro-n-octane(PFO)for ophthalmic surgery versus F-Octane as an intraoperative tamponade in pars plana vitrectomy(PPV)in management of retinal ***:This multicenter,prospective,randomized,double-masked,parallel-controlled,non-inferiority trial was conducted in three ophthalmology clinical centers in *** with retinal detachment,who were eligible for PPV were consecutively *** were assigned to PFO for ophthalmic surgery or F-Octane for intraocular tamponade in a 1:1 ***-corrected visual acuity(BCVA),intraocular pressure(IOP)measurement,and dilated fundus examination were performed preoperatively and at 1,7±1,28±3d *** primary outcome was complete retinal reattachment rate at postoperative day *** non-inferiority margin was set at 9.8%.The secondary outcomes included intraoperative retinal reattachment rate,and mean changes in IOP and BCVA from baseline to 1,7±1,28±3d postoperatively,*** analyses were presented for all randomly assigned participates in this ***:Totally 124 eligible patients completed the study between Mar.14,2016 and Jun.7,*** of them were randomly assigned to the PFO for ophthalmic surgery group,and 64 were assigned to the F-Octane *** characteristics were comparable between the two *** groups achieved 100%retinal reattachment at postoperative day one(difference 0,95%CI:-6.21%to 5.75%,P=1).The pre-defined noninferiority criterion was *** significant difference was observed in intraoperative retinal reattachment rate(difference 1.77%,P=0.61),mean changes in IOP(difference 0.36,-0.09,2.22 mm Hg at 1,7±1,28±3d postoperatively,with all P>0.05)and BCVA(difference 0.04,-0.02,0.06 logMAR at 1,7±1,28±3d postoperatively,all P>0.05)between the two *** apparent adverse events related to the utilization of PFO were ***:In patients with retinal detachment undergoing PPV,PFO

关键词： perfluoro-n-octane vitreoretinal surgery intraocular tamponade ophthalmic surgery retinal detachment

Charge density wave order and electron-boson coupling in ternary superconductor Bi_(2)Rh_(3)Se_(2)

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Science China(Physics,Mechanics & Astronomy) 2023年第7期66卷 120-126页

作者： Zi-Teng liu Chen Zhang Qi-Yi Wu Hao liu Bo Chen Zhi-Bo Yin Sheng-Tao Cui Zhe Sun Shuang-Xing Zhu Jiao-Jiao Song Yin-Zou Zhao Hong-Yi Zhang Xue-Qing Ye Fan-Ying Wu Shu-Yu liu Xiao-Fang Tang Ya-Hua Yuan yun-Peng Wang Jun He hai-yun liu Yu-Xia Duan Jian-Qiao Meng School of Physics and Electronics Central South UniversityChangsha 410083China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China Department of Physics and Electronic Science Hunan University of Science and TechnologyXiangtan 411201China Beijing Academy of Quantum Information Sciences Beijing 100085China

The newly discovered ternary chalcogenide superconductor Bi_(2)Rh_(3)Se_(2) has attracted growing attention,which provides an opportunity to explore the interplay between charge density wave(CDW)order and ***,whether the phase transition around 240 K can be attributed to the formation of CDW remains *** help resolve the debate,we study the electronic structure of Bi_(2)Rh_(3)Se_(2) by angle-resolved photoemission spectroscopy,focusing on the nature of its high-temperature phase transition around 240 *** measurements demonstrate that the phase transition at 240 K is a second-order CDW phase *** results reveal(i)a 2×2 CDW order in Bi_(2)Rh_(3)Se_(2),accompanied by the reconstruction of electronic structure,such as band folding,band splitting,and opening of CDW gaps at and away from the Fermi level;(ii)the existence of electron-boson coupling,which is manifested as an apparent kink and peak-dip-hump structure in *** observations thus enable us to shed light on the nature of CDW order and superconductivity in Bi_(2)Rh_(3)Se_(2).

关键词： charge density wave electron-boson coupling angle-resolved photoemission spectroscopy electronic structure Chalcogenide

Ultrafast optical spectroscopy evidence of pseudogap and electronphonon coupling in an iron-based superconductor KCa_(2)Fe_(4)As_(4)F_(2)

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Science China(Physics,Mechanics & Astronomy) 2022年第3期65卷 92-98页

作者： Chen Zhang Qi-Yi Wu Wen-Shan Hong Hao liu Shuang-Xing Zhu Jiao-Jiao Song Yin-Zou Zhao Fan-Ying Wu Zi-Teng liu Shu-Yu liu Ya-Hua Yuan Han Huang Jun He Shiliang Li hai-yun liu Yu-Xia Duan Hui-Qian Luo Jian-Qiao Meng School of Physics and Electronics Central South UniversityChangsha 410083China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China Beijing Academy of Quantum Information Sciences Beijing 100193China

We use ultrafast optical spectroscopy to study the nonequilibrium quasiparticle relaxation dynamics of the iron-based superconductor KCa_(2)Fe_(4)A_(s4)F_(2)with T_(c)= 33.5 K. Our results reveal a possible pseudogap(△_(PG)=(2.4 ± 0.1) me V) below T*≈ 50 K but prior to the opening of a superconducting gap(△SC(0) ≈(4.3 ± 0.1) me V). Measurements under high pump fluence reveal two distinct, coherent phonon oscillations with 1.95 and 5.51 THz frequencies, respectively. The high-frequency A1 g(2) mode corresponds to the c-axis polarized vibrations of Fe As planes with a nominal electron-phonon coupling constant λA1 g(2)= 0.194 ± *** findings suggest that the pseudogap is likely a precursor of superconductivity, and the electron-phonon coupling may play an essential role in the superconducting pairing in KCa_(2)Fe_(4)A_(s4)F_(2).

关键词： KCa_(2)Fe_(4)A_(s4)F_(2) ultrafast spectroscopy electron-phonon coupling superconductivity

Itinerant to relocalized transition of felectrons in the Kondo insulator CeRu_(4)Sn_(6)

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Frontiers of physics 2023年第5期18卷 153-160页

作者： Fan-Ying Wu Qi-Yi Wu Chen Zhang Yang Luo Xiangqi liu Yuan-Feng Xu Dong-Hui Lu Makoto Hashimoto Hao liu Yin-Zou Zhao Jiao-Jiao Song Ya-Hua Yuan hai-yun liu Jun He Yu-Xia Duan Yan-Feng Guo Jian-Qiao Meng School of Physics and Electronics Central South UniversityChangsha 410083China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Center for Correlated Matter and School of Physics Zhejiang UniversityHangzhou 310058China Stanford Synchrotron Radiation Lightsource SLAC National Accelerator LaboratoryMenlo ParkCA 94025USA Beijing Academy of Quantum Information Sciences Beijing 100085China ShanghaiTech Laboratory for Topological Physics ShanghaiTech UniversityShanghai 201210China

The three-dimensional electronic structure and the nature of Ce 4f electrons of the Kondo insulator CeRu_(4)Sn_(6)are investigated by angle-resolved photoemission spectroscopy,utilizing tunable photon *** results reveal(i)the three-dimensional k-space nature of the Fermi surface,(ii)the localized-to-itinerant transition of f electrons occurs at a much high temperature than the hybridization gap opening temperature,and(iii)the“relocalization”of itinerant f-electrons below 25 K,which could be the precursor to the establishment of magnetic order.

关键词： Kondo insulator heavy fermion ARPES electronic structure relocalization

The protective effects of α-ketoacids against oxidative stress on rat spermatozoa in vitro

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Asian Journal of Andrology 2010年第2期12卷 247-256页

作者： Shi-Feng Li hai-Xiong liu yun-Bin Zhang Yuan-Chang Yan Yi-Ping Li Laboratory of Molecular Cell Biology Shanghai Key Laboratory for Molecular Andrology Institute of Biochemistry andCell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China

The aim of this study was to determine the effects of antioxidants,including α-ketoacids （α-ketoglutarate and pyruvate）,lactate and glutamate/malate combination,against oxidative stress on rat spermatozoa. Our results showed that H2O2 （250 μmol L^-1）-induced damages,such as impaired motility,adenosine triphosphate （ATP） depletion,inhibition of sperm protein phosphorylation,reduced acrosome reaction and decreased viability,could be significantly prevented by incubation of the spermatozoa with α-ketoglutarate （4 mmol L^-1） or pyruvate （4 mmol L^-1）. Without exogenous H2O2 in the medium,the addition of pyruvate （4 mmol L^-1） significantly increased the superoxide anion （O2^-·） level in sperm suspension （P≤0.01）,whereas the addition of α-ketoglutarate （4 mmol L^-1） and lactate （4 mmol L^-1） significantly enhanced tyrosine-phosphorylated proteins with the size of 95 kDa （P≤0.04）. At the same time,α-ketoglutarate,pyruvate,lactate,glutamate and malate supplemented in media can be used as important energy sources and supply ATP for sperm motility. In conclusion,the present results show that α-ketoacids could be effective antioxidants for protecting rat spermatozoa from H2O2 attack and could be effective components to improve the antioxidant capacity ofBiggers,Whitten and Whittingham media.

关键词： α-ketoacids antioxidants oxidative stress reactive oxygen species

Growth, characterization, and Raman spectra of the 1T phases of TiTe_(2), TiSe_(2), and TiS_(2)

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Chinese Physics B 2022年第3期31卷 482-487页

作者： Xiao-Fang Tang Shuang-Xing Zhu Hao liu Chen Zhang Qi-Yi Wu Zi-Teng liu Jiao-Jiao Song Xiao Guo Yong-Song Wang He Ma Yin-Zou Zhao Fan-Ying Wu Shu-Yu liu Kai-Hui liu Ya-Hua Yuan Han Huang Jun He Wen Xu hai-yun liu Yu-Xia Duan Jian-Qiao Meng Key Laboratory of Materials Physics Institute of Solid State Physics Chinese Academy of Sciences Hefei 230031China University of Science and Technology of China Hefei 230026China School of Physics and Electronics Central South University Changsha 410083China State Key Laboratory for Mesoscopic Physics Collaborative Innovation Center of Quantum Matter School of Physics Peking UniversityBeijing 100871China Beijing Academy of Quantum Information Sciences Beijig 10085China

High-quality large 1T phase of TiX_(2)(X = Te, Se, and S) single crystals have been grown by chemical vapor transport using iodine as a transport agent. The samples are characterized by compositional and structural analyses, and their properties are investigated by Raman spectroscopy. Several phonon modes have been observed, including the widely reported A_(1g) and E_(8) modes, the rarely reported E_(u) mode(-83 cm^(-1) for TiTe_(2), and -185 cm^(-1)for TiS_(2)), and even the unexpected K mode(-85 cm^(-1)) of TiTe_(2). Most phonons harden with the decrease of temperature, except that the K mode of TiTe_(2) and the E_(u) and “A_(2u)/Sh” modes of TiS_(2) soften with the decrease of temperature. In addition, we also found phonon changes in TiSe_(2) that may be related to charge density wave phase transition. Our results on TiX_(2) phonons will help to understand their charge density wave and superconductivity.

关键词： transition-metal dichalcogenides chemical vapor transport Raman phonon

A gate enhanced power U-shaped MOSFET integrated with a Schottky rectifier

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Chinese Physics B 2012年第5期21卷 441-444页

作者：王颖焦文利胡海帆刘云涛曹菲 College of Information and Communication Engineering Harbin Engineering University.Harbin 150001China

An accumulation gate enhanced power U-shaped metal-oxide-semiconductor field-effect-transistor（UMOSFET） integrated with a Schottky rectifier is *** this device,a Schottky rectifier is integrated into each cell of the accumulation gate enhanced power *** on-resistances of 7.7 *** 2 and 6.5 *** 2 for the gate bias voltages of 5 V and 10 V are achieved,respectively,and the breakdown voltage is 61 *** numerical simulation shows a 25% reduction in the reverse recovery time and about three orders of magnitude reduction in the leakage current as compared with the accumulation gate enhanced power UMOSFET.

关键词： accumulation Schottky source reverse recovery time leakage current