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Sequence architecture and sedimentary characteristics of a Middle Jurassic incised valley,western Sichuan depression,China

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Petroleum Science 2018年第2期15卷 230-251页

作者： Jun-Long Liu Wei Yin You-Liang Ji Tian-yun Wang Fu-Xiang Huang hai-yue yu Wen-Shu Li Sinopec Exploration&Production Research Institute Beijing 100083China State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing 102249China Xinxing Geophysical Department Bureau of Geophysical ProspectingCNPCZhuozhou 072751HebeiChina Daqing Oil Company CNPCDaqing 163000HeilongjiangChina

The Middle Jurassic Shaximiao Formation encompasses tens of meters of thick lowstand meandering valley （LMV） strata in the western Sichuan foreland basin. Ancient LMVs newly discovered in this area were further studied based on sequence stratigraphy and seismic sedimentology. The aim of the present study was to investigate the sedimentary characteristics, sequence architecture, and the controls on LMV deposition in this tectonically active basin using field survey data, seismic sections, seismic amplitude imaging, core description, and comprehensive application of drilling data. The results show the following：（1） Three regional sequence boundaries and two flooding surfaces were recognized, and the Shaximiao For- mation was divided into two-third-order sequences and four systems tracts. （2） Three sedimentary facies associations were identified： incised valley-fill, tributary channel, and overbank facies. Incised valleys are 5-17 km wide, 20-60 m deep and traceable for 120 km along their axes. （3） In the downstream segment, the role of tectonism gradually diminishes, and periodic base-level changes control the form and evolution of the incised valleys. Three types of LMVs--AI, A2, and A3--developed with changes in base level （lake level）; of these types, the base level of the A3 LMV was likely the lowest.

关键词： Sequence architecture Sedimentary characteristic Lowstand meandering valley Western Sichuandepression Shaximiao Formation

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Flexible quasi-solid-state sodium-ion full battery with ultralong cycle life,high energy density and high-rate capability

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Nano Research 2022年第2期15卷 925-932页

作者： Chen-De Zhao Jin-Zhi Guo Zhen-Yi Gu Xiao-Tong Wang Xin-Xin Zhao Wen-Hao Li hai-yue yu Xing-Long Wu Faculty of Chemistry Northeast Normal UniversityJilin 130024China MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityJilin 130024China

Flexible power sources featuring high-performance,prominent flexibility and raised safety have received mounting attention in the area of wearable electronic ***,many great challenges remain to be overcome,notably the design and fabrication of flexible electrodes with excellent electrochemical performance and matching them with safe and reliable ***,a facile approach for preparing flexible electrodes,which employs carbon cloth derived from commercial cotton cloth as the substrate of cathode and a flexible anode,is proposed and *** promising cathode(NVPOF@FCC)with high conductivity and outstanding flexibility is prepared by efficiently coating Na_(3)V_(2)(PO_(4))_(2)O_(2)F(NVPOF)on flexible carbon cloth(FCC),which exhibits remarkable electrochemical performance and the significantly improved reaction *** importantly,a novel flexible quasi-solid-state sodium-ion full battery(QSFB)is feasibly assembled by sandwiching a P(VDF-HFP)-NaClO_(4) gel-polymer electrolyte film between the advanced NVPOF@FCC cathode and FCC *** the QSFBs are further evaluated in flexible pouch cells,which not only demonstrates excellent energy-storage performance in aspect of great cycling stability and high-rate capability,but also impressive flexibility and *** work offers a feasible and effective strategy for the design of flexible electrodes,paving the way for the progression of practical and sustainable flexible batteries.

关键词： flexible sodium-ion battery gel-polymer electrolyte quasi-solid-state carbon cloth Na_(3)V_(2)(PO_(4))_(2)O_(2)F

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Tempura-like carbon/carbon composite as advanced anode materials for K-ion batteries

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Journal of Energy Chemistry 2021年第8期30卷 589-598,I0012页

作者： Hao-Jie Liang Zhen-Yi Gu Xue-Ying Zheng Wen-Hao Li Ling-yun Zhu Zhong-Hui Sun yun-Feng Meng hai-yue yu Xian-Kun Hou Xing-Long Wu MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun 130024China Key Laboratory of Preparation and Application of Environmental Friendly Materials(Jilin Normal University) Ministry of EducationChangchun 130103China Institute of New Energy for Vehicles Tongji University201804 ShanghaiChina CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology100190 BeijingChina Center for Advanced Analytical Science School of Chemistry and Chemical EngineeringMOE Key Laboratory for Water Quality and Conservation of the Pearl River DeltaGuangzhou UniversityGuangzhou 510006China National&Local United Engineering Laboratory for Power Batteries Faculty of ChemistryNortheast Normal UniversityChangchun 130024China

Graphite as a promising anode candidate of K-ion batteries(KIBs)has been increasingly studied currently,but corresponding rate performance and cycling stability are usually inferior to amorphous carbon *** protect the layer structure and further boost performance,tempura-like carbon/carbon nanocomposite of graphite@pitch-derived S-doped carbon(G@PSC)is designed and prepared by a facile and low-temperature modified molten salt *** robust encapsulation structure makes their respective advantages complementary to each other,showing mutual promotion of electrochemical performances caused by synergy *** a result,the G@PSC electrode is applied in KIBs,delivering impressive rate capabilities(465,408,370,332,290,and 227 m A h g^(-1)at 0.05,0.2,0.5,1,2,and 5 A g^(-1))and ultralong cyclic stability(163 m A g^(-1)remaining even after 8000 cycles at 2 A g^(-1)).On basis of ex-situ studies,the sectionalized K-storage mechanism with adsorption(pseudocapacitance caused by S doping)-intercalation(pitch-derived carbon and graphite)pattern is ***,the exact insights into remarkable rate performances are taken by electrochemical kinetics tests and density functional theory *** a word,this study adopts a facile method to synthesize high-performance carbon/carbon nanocomposite and is of practical significance for development of carbonaceous anode in KIBs.

关键词： K-ion batteries Anode materials Carbon/carbon composite S doping Cyclic stability DFT calculation

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How to select gastric cancer patients suitable for immunotherapy?

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Clinical Research Communications 2023年第4期6卷 10-11页

作者： Ling-Ling yu Guo-Jun Zhang Bao Zhang hai-yue yu Guo-Liang Zheng Department of Integrated Chinese and Western Medicine Cancer Hospital of China Medical University(Liaoning Cancer Hospital and Institute)Shenyang 110042China Department of Pathophysiology College of Basic Medicine ScienceChina Medical UniversityShenyang 110122China Department of Gastric Surgery Cancer Hospital of China Medical University(Liaoning Cancer Hospital and Institute)Shenyang 110042China

Stomach cancer is the fourth leading cause of cancer-related deaths worldwide[1].There are approximately one million new cases of gastric cancer worldwide each year,with about 45%occurring in China[1].In China,the number of deaths from gastric cancer ranks second among all tumors each year[2],the majority of patients are diagnosed at an advanced or late stage,making them ineligible for surgical *** of these patients can regain the opportunity for surgery through conversion therapy,while more patients can only receive comprehensive treatment with cytotoxic drugs,anti-metabolite drugs,DNA-targeting drugs,and targeted drugs[3].

关键词： drugs patients cancer

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CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system

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Neural Regeneration Research 2025年第8期20卷 2420-2432页

作者： Lin Yin Yalan Xu Jie Mu yu Leng Lei Ma yu Zheng Ruizhi Li Yin Wang Peifeng Li hai Zhu Dong Wang Jing Li Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina School of Basic Medicine Qingdao UniversityQingdaoShandong ProvinceChina College of Life Sciences and School of PharmacyMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina Department of Urology Qingdao Municipal Hospital Affiliated to Qingdao UniversityQingdaoShandong ProvinceChina

The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding *** of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully *** has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic ***,the function of CNKSR2 in the cytoplasm remains to be *** this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of *** a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the *** also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker *** colocalization analysis confirmed the centrosomal localization of *** we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal *** manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and ***,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum *** findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.

关键词： autism spectrum disorder centrosome CNKSR2 intellectual disability interactome mass spectrometry microtubule neurodevelopmental disease protein complexes protein-protein interactions

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Visible-light-responsive homologous heterostructure of oxynitrides constructed to boost charge separation and water splitting

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Science China Chemistry 2025年第01期 186-191页

作者： hai Zou yunfeng Bao Xueshang Xin yu Qi Tengfeng Xie Fuxiang Zhang State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences School of Chemistry and Chemical Engineering Liaoning Normal University College of Chemistry Jilin University

Constructing type II heterostructures represents a widely recognized strategy for enhancing charge separation and photocatalytic efficiency,but it remains challenging to fabricate homologous heterostructures based on visible-light-responsive semiconductors,especially for popularly investigated （oxy）nitrides with low thermal ***,we synthesized a homologous heterostructure （denoted as YTON＿H） based on the oxynitrides of YTaO4-xNyand YTa *** heterostructure exhibits type II band structure alignment and intimate interface achieved through a magnesium （Mg） powder-assisted nitridation *** with widely reported heterologous heterostructures,the as-obtained YTON＿H homologous heterostructure could similarly exhibit enhanced charge separation as well as photocatalytic water splitting performance with respect to its counterparts(YTaO4-xNyand YTaON2).Meanwhile,detailed structural characterizations and spectroscopy analysis have been made to confirm the formation of heterostructure and promotion of spatial charge separation.

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膨体弹力真丝超分子结构与特性研究

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丝绸 2002年第5期39卷 12-14页

作者：管新海陈宇岳林红苏州大学材料工程学院江苏苏州215021

通过测定膨体弹力真丝的结晶度、取向程度、力学松弛和断裂比功等特性 ,研究膨体弹力真丝与普通生丝在超分子结构、应力松弛和蠕变等方面的特征 ,探讨其分子结构与力学特性的内在联系以及它们对膨体弹力真丝性能的影响。

关键词：膨体弹力真丝超分子结构力学特性

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Design high-performance narrowband emitters for blue light-emitting diodes through manipulating resonance structure of aromatic heterocycles

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Science China Chemistry 2025年

作者： yue yu Lei Xu Wenle Tan yuyu Pan Jiyin Xiao Bohan Wang Guangjun Tian yuguang Ma Lei Ying Institute of Polymer Optoelectronic Materials and Devices Guangdong Basic Research Center of Excellence for Energy and Information Polymer Materials State Key Laboratory of Luminescent Materials and Devices South China University of Technology School of Petrochemical Engineering Shenyang University of Technology Key Laboratory for Microstructural Material Physics of Hebei Province School of Science Yanshan University

Narrowband light-emitting materials play critical roles in improving the color gamut and energy consumption of electroluminescence. Herein we demonstrated that by regulating the ground state resonance structure form of emitters with polycyclic aromatic heterocycles, the high-energy vibration of the C–C bond can be effectively suppressed, resulting in narrow emission like classical cyanine dyes. The designed compounds consist of twist and planar conformation, while having differences in the orientation of the positioning electron-donating(nitrogen) and electron-accepting(carbonyl) groups in the polycyclic aromatic hydrocarbon skeleton. The resulting compound Ac-Ph-Ac with a dominated zwitterionic resonance structure exhibits a relatively wide electroluminescent profile with the full width at half maximum(FWHM) of 42 nm and moderate device performance. In contrast, the “soliton transition” of 2AcPh based on the cyanine limit character effectively suppresses C–C stretching vibration in the polycyclic aromatic heterocycle skeleton, leading to a narrow electroluminescent profile with FWHM of 30 nm(0.16 eV)associated with an impressively high external quantum efficiency of 28.52%, which is among the highest efficiencies of so far reported non-sensitized organic light-emitting diodes.

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OCT与mf-ERG在CSCR中的应用进展

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国际眼科杂志 2015年第9期15卷 1563-1566页

作者：查文丽陈梅珠余海跃王云鹏南京军区福州总医院眼科中国福建省福州市350025

中心性浆液性脉络膜视网膜病变(CSCR)为我国常见眼底疾病。近年来OCT在研究CSCR视网膜下渗出及分析视网膜结构改变等方面发挥着重要作用,同时脉络膜深层成像OCT(EDI-OCT)清晰地呈现了脉络膜形态学改变。此外,多焦视网膜电图(mf-ERG)证实... 详细信息

中心性浆液性脉络膜视网膜病变(CSCR)为我国常见眼底疾病。近年来OCT在研究CSCR视网膜下渗出及分析视网膜结构改变等方面发挥着重要作用,同时脉络膜深层成像OCT(EDI-OCT)清晰地呈现了脉络膜形态学改变。此外,多焦视网膜电图(mf-ERG)证实了CSCR所引起的视网膜功能障碍,OCT和mf-ERG联合应用可以更好的理解CSCR结构和功能异常间的相关性。众多新技术的广泛应用,为CSCR的临床诊治、预后评估及随访提供了线索和依据。

关键词：中心性浆液性脉络膜视网膜病变视网膜下积液视网膜外核层内-外节连接体带外界膜脉络膜厚度多焦视网膜电图

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan yu Xiao-Li Li Xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu Xiao-Jia Yang Qian-Ru He Fei Ding hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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