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基于RBF神经网络的语音情感识别

四川理工学院学报（自然科学版） 2011年第5期24卷 552-555页

作者：张海燕唐建芳四川理工学院理学院四川自贡643000

介绍了径向基函数神经网络的原理、训练算法,并建立了RBF神经网络的语音情感识别的模型。在实验中比较了BP神经网络与RBF神经网络分别用于语音情感识别识别率,RBF神经网络的平均识别率高于BP神经网络3%。结果表明,基于RBF神经网络的语... 详细信息

介绍了径向基函数神经网络的原理、训练算法,并建立了RBF神经网络的语音情感识别的模型。在实验中比较了BP神经网络与RBF神经网络分别用于语音情感识别识别率,RBF神经网络的平均识别率高于BP神经网络3%。结果表明,基于RBF神经网络的语音情感识别方法的有效性。

关键词：径向基函数 RBF神经网络语音情感识别

Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats

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Chinese Journal of Integrative Medicine 2018年第9期24卷 661-669页

作者： tang Li-rui TAO yan-yan LIU Cheng-hai WANG hai-nan Institute of Liver Diseases Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 2201203 China Department of Emergency Medicine Putuo Hospital affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 2200062 China Shanghai Key Laboratory of Traditional Chinese Medicine Shanghai 2201203 China E-Institute of Traditional Chinese Medicine Internal Medicine Shanghai Municipal Education Commission Shanghai 2201203 China China Food and Drug Administration Beijing 2100053 China

Objective： To evaluate the preventive effect of salvianolate （Sal B） on glucose metabolism disorders of dimethylnitrosamine （DMN）-induced cirrhotic rats. Methods： Fiffy-five Wistar rats were randomly divided into a control group （n=10） and a cirrhotic group （n=45） according to a random number table. Liver cirrhosis was induced by intraperitoneal administration of DMN. The cirrhotic rats were divided into model, Sal B and metformin groups （n=15）, respectively. Rats in the model group were given saline, two treatment groups were given Sal B （50 mg/kg）, metformin （150 mg/kg） respectively for 28 consecutive days, while rats in the control group were injected 0.9% saline with same volume of vehicle. Body weight was measured everyday. Insulin sensitivity was determined by euglycemic hyperinsulinemic clamp. Organ index, glucose tolerance test （OGTT）, and fasting plasma glucose （FPG）, fasting insulin （FINS）, hepatic glycogen, hydroxyproline （HYP） and liver function were detected at the end of the treatment. Area under the curve （AUC） for OG3-1 was calculated. Liver and pancreas histology were determined by histopathological examination with hematoxylin and eosin staining （HE）, Sirius Red staining and Masson＇s trichrome staining, respectively. Hepatic expression of α-smooth muscle actin （oL-SMA） and collagen （Col I ） were evaluated by immunohistochemical staining. Results： Compared with the model group, Sal B significantly increased body and liver weight, liver-body ratio, glucose infusion rate （GIR）, FPG, FINS levels and hepatic glycogen at the end of administration （P〈0.05 or P〈0.01）. Meanwhile, Sal B significantly decreased AUC for OGI-I＇, spleen weight, spleen-body ratio, aminotransferase and HYP level （P〈0.05 or P〈0.01）. Sal B was also effective in alleviating necrosis of liver tissue, suppressing fibrosis progression and inhibiting the expression of oL-SMA and Col I in liver. Compared with the metformin group, Sal B had advantages in ameliorating FPG, hepatic glycogen,

关键词： salvianolate fibrosis cirrhosis insulin resistance glycogen metformin

Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

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Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun tang Fan Fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population drug

PDCA循环管理在提高首台择期手术准点率中的应用

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中国当代医药 2017年第15期24卷 145-147页

作者：谭海燕钟彩棠区敏玲刘彩颜广东省佛山市顺德区龙江医院手术室广东佛山528318 广东省佛山市顺德区龙江医院护理部广东佛山528318

目的研究并探讨PDCA循环管理在提高首台择期手术准点率中的应用效果。方法收集2015年1~12月我院择期手术治疗的200例患者为研究对象,对其首台择期手术准点开台情况及影响因素进行分析;2016年1~12月在我院手术管理中引入PDCA循环管理理念... 详细信息

目的研究并探讨PDCA循环管理在提高首台择期手术准点率中的应用效果。方法收集2015年1~12月我院择期手术治疗的200例患者为研究对象,对其首台择期手术准点开台情况及影响因素进行分析;2016年1~12月在我院手术管理中引入PDCA循环管理理念,落实相应管理对策,选取200例择期手术患者进行对比研究,比较PDCA循环管理实施前后患者的首台择期手术准点率、接台手术准点率、手术交接时间、接台手术间隔时间、医生满意度。结果相比PDCA循环管理实施前,实施后患者的首台择期手术准点率、接台手术准点率均明显提高(P<0.05),其手术交接时间、接台手术间隔时间明显缩短(P<0.05),且医生对手术管理的满意度明显提高(P<0.05)。结论在手术室管理中采取PDCA循环管理模式,可有效提高首台择期手术准点率,有利于缩短接台手术间隔时间,从而提高手术室的周转效率。

关键词：手术室护理管理首台择期手术准点开台 PDCA循环

Prefrontocortical Astrocytes Regulate Dominance Hierarchy in Male Mice

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Neuroscience Bulletin 2024年第3期40卷 415-417页

作者： Yong tang hai-yan Yin Peter Illes School of Acupuncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu 610075China International Joint Research Center on Purinergic Signaling Chengdu University of Traditional Chinese MedicineChengdu 610075China Rudolf Boehm Institute for Pharmacology and Toxicology University of Leipzig04107 LeipzigGermany

Social hierarchy is a general self-organizational scheme in animal societies in which each member achieves a certain status of domination or subordination when getting access to resources,with profound consequences for survival,health,reproductive success,and multiple behaviors[1,2].The prefrontal cortex(PFC)was recognized as a central regulator of neuronal circuits determining the formation of social hierarchy;brain areas upstream of the PFC convey information about social status,and downstream brain regions execute dominance behavior[3].Social deficits have been suggested to be due to an elevation of excitatory/inhibitory(E/l)balance within the mouse dorsomedial(dm)PFC[4].A compensatory increase of inhibitory cell excitability partially rescued social deficits caused by such a disturbance of E/l balance.

关键词： consequences hierarchy determining

Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-yan Zhang Fang-Yu Wang Xiao-Hui Yu Shan-Hong tang Hong-Wu Zhu Ya-Gang Zhao Ji-Luo Liu Jian Wang Jing-Han Guo Xiao-Mei Zhang Yun-Sheng yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study

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园林废弃物堆肥配制基质的防病解磷效果研究

安徽农业科学 2018年第22期46卷 122-124页

作者：鄢海印唐志远吕浩荣刘可星广东顺德东部新城城市管理有限公司广东佛山528300 华南农业大学资源环境学院广东广州510642

[目的]研究不同园林废弃物堆肥配制基质的防病解磷效果。[方法]利用不同接种方式的园林废弃物堆肥配制基质,进行番茄栽培试验,分析基质微生物群落功能、解磷以及防治青枯病的效果。[结果]接种复合菌剂堆肥配制的基质具有一定的防病效果... 详细信息

[目的]研究不同园林废弃物堆肥配制基质的防病解磷效果。[方法]利用不同接种方式的园林废弃物堆肥配制基质,进行番茄栽培试验,分析基质微生物群落功能、解磷以及防治青枯病的效果。[结果]接种复合菌剂堆肥配制的基质具有一定的防病效果,可以提高微生物总体活性、群落物种丰富度,促进番茄生长,增加吸磷量,提高基质中速效磷和水溶性磷含量。后期接种堆肥配制基质的防病效果最优,而2次接种堆肥配制基质的解磷效果最好。[结论]该研究为防病、解磷功能型营养基质的研制提供理论基础和实践依据。

关键词：园林废弃物堆肥基质防病解磷微生物多样性

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling Chen Danyang Chen Gaigai Li Zhouping tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

PROK2–PROKR2 Signaling:New Contributor to Pleasant Touch

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Neuroscience Bulletin 2023年第2期39卷 356-358页

作者： Feng-Lin Chen hai-yan Yin Yong tang School of Acupuncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu 610075China Acupuncture and Chronobiology Key Laboratory of Sichuan Province Chengdu 610075China School of Health and Rehabilitation Chengdu University of Traditional Chinese MedicineChengdu 610075China

Pleasant touch sensation derived from hugging,cuddling,holding hands,or massage therapy can provide powerful benefits for patients with psychiatric disorders and play a crucial role in reducing pain,alleviating stress,and strengthening social *** the underlying mechanisms of pleasant touch is an attractive topic in neuroscience[1].The peripheral pathway for pleasant touch is mainly coded by C-tactile(CT)afferents,activated by touches with velocities between 1 and 10cm/s[2].

关键词： sensation attractive Touch