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On the Seidel Integral Complete Multipartite Graphs

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Acta Mathematicae Applicatae Sinica 2012年第4期28卷 705-710页

作者： Sheng-mei LV Liang WEI hai-xing zhao Department of Mathematics Qinghai Nationality University Department of Mathematics Qinghai Normal University

For a simple undirected graph G, denote by λ（G） the （0, 1）-adjacency matrix of G. Let the matrix S（G） = J-I-2A（G） be its Seidel matrix, and let SG（A） = det（AI-S（G）） be its Seidel characteristic polynomial, where I is an identity matrix and J is a square matrix all of whose entries are equal to 1. If all eigenvalues of SG（λ） are integral, then the graph G is called S-integral, In this paper, our main goal is to investigate the eigenvalues of SG（A） for the complete multipartite graphs G = Kn1,n2,...,n,. A necessary and sufficient condition for the complete tripartite graphs Km,n,t and the complete multipartite graphs Km,.... m,n,...,n to be S-integral is given, respectively.

关键词： S-polynomial S-integral complete multipartite graphs

Biological factors driving colorectal cancer metastasis

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 259-272页

作者： Shuai-xing An zhao-Jin Yu Chen Fu Min-Jie Wei Long-hai Shen Department of Pharmacology School of PharmacyChina Medical UniversityShenyang 110122Liaoning ProvinceChina Liaoning Key Laboratory of Molecular Targeted Antitumor Drug Development and Evaluation Liaoning Cancer Immune Peptide Drug Engineering Technology Research CenterKey Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors(China Medical University)Ministry of EducationShenyang 110122Liaoning ProvinceChina BD Department Greenpine Pharma Group Co.LtdTianjin 300020China Center of Oncology Genertec Liaoyou Gem Flower HospitalPanJin 124010Liaoning ProvinceChina

Approximately 20%of colorectal cancer(CRC)patients present with metastasis at *** Stage I-III CRC patients who undergo surgical resection,18%typically suffer from distal metastasis within the first three years following initial *** median survival duration after the diagnosis of metastatic CRC(mCRC)is only 9 *** is traditionally considered to be an advanced stage malignancy or is thought to be caused by incomplete resection of tumor tissue,allowing cancer cells to spread from primary to distant organs;however,increa-sing evidence suggests that the mCRC process can begin early in tumor *** patients present with high heterogeneity and diverse cancer phenotypes that are classified on the basis of molecular and morphological *** genomic and nongenomic events can induce subclone diversity,which leads to cancer and *** the course of mCRC,metastatic cascades are associated with invasive cancer cell migration through the circulatory system,extravasation,distal seeding,dormancy,and reactivation,with each step requiring specific molecular ***,cancer cells presenting neoantigens can be recognized and eliminated by the immune *** this review,we explain the biological factors that drive CRC metastasis,namely,genomic instability,epigenetic instability,the metastatic cascade,the cancer-immunity cycle,and external lifestyle *** remarkable progress in CRC research,the role of molecular classification in therapeutic intervention remains *** review shows the driving factors of mCRC which may help in identifying potential candidate biomarkers that can improve the diagnosis and early detection of mCRC cases.

关键词： cancer Metastasis cascade Cancer immunity Genomic variation Epigenetic instability Lifestyle factor

Ancient mitochondrial genome depicts sheep maternal dispersal and migration in Eastern Asia

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Journal of Genetics and Genomics 2024年第1期51卷 87-95页

作者： Liu Yang xing Zhang Yaning Hu Piao Zhu Hua Li Zhenyu Peng hai Xiang Xinying Zhou xingbo zhao National Engineering Laboratory for Animal Breeding Key Laboratory of AnimalGeneticsBreeding and ReproductionMinistry of Agriculture and Rural AffairsCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding School of Life Science and EngineeringFoshan UniversityFoshanGuangdong 528225China State Key Laboratory of Agricultural Genomics BGI-ShenzhenShenzhenGuangdong 518083China Key Laboratory of Vertebrate Evolution and Human Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China

Sheep have been one of the most important groups of animals since ancient ***,the knowledge of their migration routes and genetic relationships is still poorly *** investigate sheep maternal migration histories alongside Eurasian communications routes,in this study,we obtain mitochondrial genomes(mitogenomes)from 17 sheep remains in 6 Chinese sites and 1 Uzbekistan site dated 4429–3100 years before present(BP).By obtaining the mitogenomes from the sheep(4429–3556 BP)found in the Tongtian Cave site in Xinjiang,Altai region of northwest China,our results support the emergence of haplogroup C sheep in Xinjiang as early as 4429–3556 *** combined phylogenetic analyses with extant ancient and modern sheep mitogenomes suggest that the Uzbekistan-Altai region may have been a migration hub for early sheep in eastern *** least two migration events have taken place for sheep crossing Eurasia to China,one passing by Uzbekistan and Northwest China to the middle and lower reaches of the Yellow River at approximately 4000 BP and another following the Altai region to middle Inner Mongolia from 4429 BP to 2500 ***,this study provides further evidence for early sheep utilization and migration patterns in Eastern Asia.

关键词： Sheep Ancient DNA Eastern Asia Mitochondrial genome Migration Altai

Accelerated Primal-Dual Projection Neurodynamic Approach With Time Scaling for Linear and Set Constrained Convex Optimization Problems

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1485-1498页

作者： You zhao xing He Mingliang Zhou Tingwen Huang Chongqing Key Laboratory of Nonlinear Circuits and Intelligent Information Processing College of Electronic and Information EngineeringSouthwest UniversityChongqing 400715China School of Computer Science Chongqing UniversityChongqing 400044China Department of Mathematics Texas A&M University at QatarDoha 23874Qatar IEEE

The Nesterov accelerated dynamical approach serves as an essential tool for addressing convex optimization problems with accelerated convergence *** previous studies in this field have primarily concentrated on unconstrained smooth con-vex optimization *** this paper,on the basis of primal-dual dynamical approach,Nesterov accelerated dynamical approach,projection operator and directional gradient,we present two accelerated primal-dual projection neurodynamic approaches with time scaling to address convex optimization problems with smooth and nonsmooth objective functions subject to linear and set constraints,which consist of a second-order ODE(ordinary differential equation)or differential conclusion system for the primal variables and a first-order ODE for the dual *** satisfying specific conditions for time scaling,we demonstrate that the proposed approaches have a faster conver-gence *** only requires assuming convexity of the objective *** validate the effectiveness of our proposed two accel-erated primal-dual projection neurodynamic approaches through numerical experiments.

关键词： Accelerated projection neurodynamic approach lin-ear and set constraints projection operators smooth and nonsmooth convex optimization time scaling.

Design and synthesis of thiol-terminated imidothioether oligomer as thermally latent hardener and modifier for high-performance epoxy/thiol thermosets

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Science China Chemistry 2024年第2期67卷 632-641页

作者： xing Liu Jianjun Zhou Shumei Liu Jianqing zhao School of Materials Science and Engineering South China University of TechnologyGuangzhou510640China Key Lab Guangdong High Property&Functional Polymer Materials Key Laboratory of Polymer Processing EngineeringMinistry of EducationGuangzhou510640China

Conventional base-catalyzed epoxy/aliphatic thiol systems have a poor storage stability,and are impossible to be one-pot systems.A widely accepted solution is to use the latent catalysts,which are usually insoluble anionic initiators sensitive to impurities and moisture,and have many limitations in practical *** this work,a soluble thiol-terminated imidothioether oligomer(TPI) was synthesized and used as a latent hardener and modifier to prepare one-pot epoxy/thiol systems without the latent *** latent behavior and curing mechanism of epoxy systems(EP/TPI series),consisted of bisphenol A diglycidyl ether(DGEBA),pentaerythritol tetrakis(mercaptoacetate)(PETMP) and TPI,were *** thiol exchange reaction between TPI and PETMP preceded the curing reaction of DGEBA,and produced aromatic thiols,which were unreactive at ambient conditions and reacted with DGEBA to form the thermosets at temperatures above 130 ℃.At the loading of 24.4 wt%TPI,the epoxy system(EP/TPI-3) had a shelf life of 13 days and was completely cured within 20 min at 180 ℃.Meanwhile,the catalyst-free curing process of EP/TPI-3 system was insensitive to impurities and ***,the thermal and mechanical properties of EP/TPI-3 thermoset were simultaneously improved,thereinto,the glass transition temperature,Young's modulus and ultimate tensile strength were increased by 16.7 ℃,12.9%,and 13.6%,respectively,compared with those of the commercial DGEBA/PETMP *** work shows that TPI has the potential to be a powerful alternative to commercial latent catalysts,and EP/TPI thermosets with high performance have broad application prospects.

关键词： thiol-terminated imidothioether oligomer epoxy systems thiol exchange reaction thermal latency high performance

Chromaticity of Complete 6-Partite Graphs with Certain Star or Matching Deleted Ⅱ

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Acta Mathematicae Applicatae Sinica 2013年第1期29卷 35-42页

作者： Roslan Hasni Ameen Shaman Ameen Yee-Hock Peng hai-xing zhao School of Mathematical Sciences Universiti Sains Malaysia Department of Mathematics and Institute for Mathematical Research University Putra Malaysia Department of Mathematics Qinghai Normal University

Let P（G, λ） be the chromatic polynomial of a graph G. Two graphs G and H are said to be chromatically equivalent, denoted G N H, if P（G, λ） = P（H, λ）. We write [G] = {HIH - G}. If [G] = {G}, then G is said to be chromatically unique. In this paper, we first characterize certain complete 6-partite graphs with 6rid＋1 vertices according to the number of 7-independent partitions of G. Using these results, we investigate the chromaticity of G with certain star or matching deleted. As a by-product, many new families of chromatically unique complete 6-partite graphs with certain star or matching deleted are obtained.

关键词： chromatic polynomial chromatically closed chromatic uniqueness

Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health

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Chinese Journal of Integrative Medicine 2024年第2期30卷 171-180页

作者： zhao Wen-xiao WANG Tong ZHANG Ya-nan CHEN Qian WANG Yuan xing Yan-qing ZHENG Jun DUAN Chen-chen CHEN Lijun zhao hai-jun WANG Shijun School of Nursing Shandong University of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineJi'nan(250355)China Shandong Co-innovation Center of Classic Traditional Chinese Medicine Formula Shandong University of Traditional Chinese MedicineJi'nan(250355)China College of Traditional Chinese Medicine Shandong University of Traditional Chinese MedicineJinan(250355)China

The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity,type 2 diabetes mellitus,heart failure,and non-alcoholic fatty liver *** extracted from Chinese medicine(CM)can not only alleviate pathological status but also promote health by anti-inflammatory,regulating immunity,lowering blood glucose and lipids,anti-cancer,and *** alterations of gut microbiota composition and metabolism pathways are the potential mechanisms of CM polysaccharides *** addition,they exert functions through gut-organ axis or play an indirect role by synergistic actions with other drugs or components mediated by gut *** review summarizes the molecular mechanisms of CM polysaccharides interacted with intestinal microbial inhabitants as potential prebiotics forpromoting health.

关键词： Chinese medicine polysaccharides gut microbiota short-chain fatty acids lipopolysaccharides gut-organaxis synergistic actions

Differential Evolution Hemivariational Inequalities with Anti-periodic Conditions

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Acta Mathematica Sinica,English Series 2024年第4期40卷 1143-1160页

作者： Jing zhao Chun Mei GAN Zhen hai LIU School of Mathematics and Quantitative Economics Guangxi University of Finance and EconomicsNanning 530003P.R.China Guangxi Colleges and Universities Key Laboratory of Optimization Control and Engineering Calculation Guangxi Minzu UniversityNanning 530006P.R.China

The goal of this paper is to deal with a new dynamic system called a differential evolution hemivariational inequality(DEHVI)which couples an abstract parabolic evolution hemivariational inequality and a nonlinear differential equation in a Banach ***,by apply ing surjectivity result for pseudomonotone multivalued mappins and the properties of Clarke's subgradient,we show the nonempty of the solution set for the parabolic hemivariational ***,some topological properties of the solution set are established such as boundedness,closedness and ***,we explore the upper semicontinuity of the solution ***,we prove the solution set of the system(DEHVI)is nonempty and the set of all trajectories of(DEHVI)is weakly compact in C(I,X).

关键词： Differential parabolic hemivariational inequality Clarke subdifferential hyperbolicparabolic system parabolic-parabolic system existence result

Annexin A1 in the nervous and ocular systems

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Neural Regeneration Research 2024年第3期19卷 591-597页

作者： Aijia Wang Hong Zhang xing Li Yin zhao Department of Ophthalmology 2Department of AnesthesiologyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

The therapeutic potential of Annexin A1,an important member of the Annexin superfamily,has become evident in results of experiments with multiple human systems and animal *** anti-inflammatory and pro-resolving effects of Annexin A1 are characteristic of pathologies involving the nervous *** this review,we initially describe the expression sites of Annexin A1,then outline the mechanisms by which Annexin A1 maintains the neurological homeostasis through either formyl peptide receptor 2 or other molecular approaches;and,finally,we discuss the neuroregenerative potential qualities of Annexin *** eye and the nervous system are anatomically and functionally connected,but the association between visual system pathogenesis,especially in the retina,and Annexin A1 alterations has not been well ***,we explain the beneficial effects of Annexin A1 for ocular diseases,especially for retinal diseases and glaucoma on the basis of published findings,and we explore present and future delivery strategies for Annexin A1 to the retina.

关键词： Annexin A1(ANXA1) glaucoma nervous system neuroprotection neuroregeneration ocular disease retina