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OPTIMIZATION OF DISPLACEMENT AND GLIDING PATH AND IMPROVEMENT OF PERFORMANCE FOR AN UNDERWATER THERMAL GLIDER

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Journal of Hydrodynamics 2010年第5期22卷 618-625页

作者： YANG hai MA Jie State Key Laboratory of Ocean Engineering Shanghai Jiao Tong University Shanghai 200030 China

The underwater thermal glider utilizes ocean thermal energy to change its buoyancy, which enables it to ascend and descend. A Phase Change Material （PCM） as the working fluid inside the thermal engine tubes is sensitive to the surrounding seawater temperature, whose effects are different with the various displacements and gliding angles of the glider. In this paper, the effects of the displacement and the gliding angle on the performance of the thermal engine were studied numerically and experimentally. On this basis, the ways to eliminate the negative effect of a thermocline on the performance of the thermal engine were obtained. The results show that the displacement and gliding angle affect the transition time of the PCM. There exist the threshold values of the displacement and gliding angle for the normal work of thermal engine. There are two means of eliminating the negative effect of a thermocline on the performance of the thermal engine and improving glider performance： one is to increase the displacement, and the other is to decrease the absolute value of the gliding angle. There is also another better way to improve glider performance.

关键词： displacement gliding angle underwater thermal glider Phase Change Material (PCM)

Corrosion Resistance and Semiconducting Properties of Passive Films Formed on 00Cr13Ni5Mo2 Supermartensitic Stainless Steel in Cl^- Environment

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Journal of Iron and Steel Research International 2014年第6期21卷 630-636页

作者： De-ning ZOU Rong LIU jiao LI Wei ZHANG Duo WANG Ying HAN School of Metallurgy and Engineering Xi'an University of Architecture and Technology State Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong University Key Laboratory of Advanced Structural Materials of Ministry of Education Changchun University of Technology

The semiconducting properties of passive films grown on 00Crl3Ni5Mo2 supermartensitic stainless steel were investigated in comparison with conventional 2Cr13 martensitic stainless steel. Cyclic vohammetry and electro- chemical impedance spectroscopy （EIS） were used for the studies. 00Crl3NiSMo2 steel exhibited a good corrosion resistance performance, attributing to its passive capability. The results of Mott-Schottky analysis demonstrated n- type semiconductors for the passive films with doping densities of about 1020- 1021 cm -3, and the thickness of space- charge layers was also calculated. The experimental results confirmed that Mo plays an important role in improving the corrosion resistance of 00Crl3Ni5Mo2 steel due to its impact on the doping density.

关键词： stainless steel cyclic voltammetry EIS XPS passive film 00Crl3NiSMo2

Nonalcoholic fatty pancreas disease:An emerging clinical challenge

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World Journal of Clinical Cases 2021年第23期9卷 6624-6638页

作者： Cheng-Lei Zhang Jing-jiao Wang Jian-ning Li Yi Yang Department of Clinical Laboratory General Hospital of Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina The Institute of Endocrinology Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Department of Stomatology General Hospital of Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina School of Basic Medical Sciences Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina

Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent *** describes fat accumulation in the pancreas with insignificant alcohol consumption,but the pathogenesis is largely unknown.A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation,but NAFPD remains an under-recognized and non-independent ***,age,sex,race,and unhealthy lifestyle are established independent risk factors for NAFPD,which is strongly associated with metabolic syndrome,type 2 diabetes,pancreatitis,pancreatic fistula,pancreatic cancer,and nonalcoholic fatty liver *** present,imaging techniques are common diagnostic aids,but uniform criteria and consensus are ***,healthy diet,weight loss,and exercise are the mainstays to reduce pancreatic fat *** can be seen that there is a limited understanding of NAFPD at this stage and further exploration is *** studies have revealed that NAFPD may directly affect diagnosis and clinical ***,exploring the pathophysiological mechanism and clinical associations of NAFPD is a major challenge for researchers and clinicians.

关键词： Nonalcoholic fatty pancreatic disease Pancreatic steatosis Obesity Metabolic syndrome Pancreatic disease Pancreas

Iron-mediated cross dehydrogenative coupling(CDC) of terminal alkynes with benzylic ethers and alkanes

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Science China Chemistry 2012年第1期55卷 50-54页

作者： XIANG Shi-Kai ZHANG Bo ZHANG Li-He CUI YuXin jiao ning State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Shanghai Key Laboratory of Green Chemistry and Chemical Processes Department of ChemistryEast China Normal UniversityShanghai 200062China

Iron-mediated sp-sp3 C-C bond formation through the cross dehydrogenative coupling(CDC) of terminal alkynes with benzylic ethers or alkanes has been *** inexpensive iron salt is used as the catalyst to make this transformation environmentally ***-mediated sp-sp3 C-C bond formation through the cross dehydrogenative coupling(CDC) of terminal alkynes with benzylic ethers or alkanes has been *** inexpensive iron salt is used as the catalyst to make this transformation environmentally benign.

关键词： iron cross dehydrogenative coupling terminal alkynes benzylic ethers

不同来水流量下黄土堰塞坝溃口展宽历程的水槽试验研究

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灾害学 2025年第1期40卷 180-186页

作者：焦其宪马鹏辉吴靓彭建兵李泽坤韩宁陈立森冉林长安大学地质工程与测绘学院陕西西安710054 青海省地质环境监测总站青海西宁810008

黄土在水流作用下容易遭受侵蚀,不同流量的来水对黄土堰塞坝的溃决过程和溃口扩展方式有显著影响。该文通过一系列水槽实验,流量分别为0.6 L/s、0.8 L/s、1.0 L/s、1.2 L/s和1.5 L/s,得到以下结论:①当来水流量Q≤1.0 L/s时溃口展宽为... 详细信息

黄土在水流作用下容易遭受侵蚀,不同流量的来水对黄土堰塞坝的溃决过程和溃口扩展方式有显著影响。该文通过一系列水槽实验,流量分别为0.6 L/s、0.8 L/s、1.0 L/s、1.2 L/s和1.5 L/s,得到以下结论:①当来水流量Q≤1.0 L/s时溃口展宽为短暂历程,经历溃口贯通一个过程;来水流量Q>1.0 L/s时溃口展宽为完整历程,经历溃口贯通、快速发展、稳定三个过程;②溃口快速发展阶段中,侵蚀深度和坡角控制着溃口两侧土体的稳定性,坝顶溃口形态以及溃决流量的变化反映侵蚀方向和强度的变化;③黄土的水敏性促进了管涌现象的出现,使得坝体内部侵蚀更为剧烈,导致溃口展宽出现短暂历程;④完整历程模式下洪水迅速强烈地冲击下游,而短暂历程模式需要持续稳定的应急措施来应对洪水风险。能够为黄土堰塞坝的溃决机理和防治措施提供参考支持。

关键词：黄土堰塞坝来水流量溃口展宽侵蚀特征水槽试验

Lysine 2-hydroxyisobutyrylation levels determined adipogenesis and fat accumulation in adipose tissue in pigs

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Journal of Animal Science and Biotechnology 2024年第5期15卷 2093-2105页

作者： Enfa Yan Mingyang Tan ning jiao Linjuan He Boyang Wan Xin Zhang Jingdong Yin State Key Laboratory of Animal Nutrition and Feeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China College of Animal Science and Veterinary Medicine Shandong Agricultural UniversityTaian 271018Shandong ProvinceChina Molecular Design Breeding Frontier Science Center of the Ministry of Education(MOE) Beijing 100193China

Background Excessive backfat deposition lowering carcass grade is a major concern in the pig industry,especially in most breeds of obese type *** mechanisms involved in adipogenesis and fat accumulation in pigs remain *** 2-hydroxyisobutyrylation(Khib),is a novel protein post-translational modification(PTM),which play an important role in transcription,energy metabolism and metastasis of cancer cells,but its role in adipogenesis and fat accumulation has not been *** In this study,we first analyzed the modification levels of acetylation(Kac),Khib,crotonylation(Kcr)and succinylation(Ksu)of fibro-adipogenic progenitors(FAPs),myogenic precursors(Myo)and mesenchymal stem cells(MSCs)with varied differentiation potential,and found that only Khib modification in FAPs was significantly higher than that in ***,in parallel with its regulatory enzymes lysine acetyltransferase 5(KAT5)and histone deacetylase 2(HDAC2)protein levels,the Khib levels increased quadratically(P<0.01)during adipogenic differentiation of ***5 knockdown in FAPs inhibited adipogenic differentiation,while HDAC2 knockdown enhanced adipogenic *** also demonstrated that Khib modification favored to adipogenic differentiation and fat accumulation by comparing Khib levels in FAPs and backfat tissues both derived from obese-type pigs(Laiwu pigs)and lean-type pigs(Duroc pigs),***,the expression patterns of KAT5 and HDAC2 matched well to the degree of backfat accumulation in obese-and lean-type *** From the perspective of protein translational modification,we are the first to reveal the role of Khib in adipogenesis and fat deposition in pigs,and provided new clues for the improvement of fat accumulation and distribution as expected via genetic selection and nutritional strategy in obese-type pigs.

关键词： Adipogenesis Backfat Fat accumulation 2-Hydroxyisobutyrylation Intramuscular fat content Pigs

Influence of Spur Dike on Hydrodynamic Exchange Between Channel and Shoal of Generalization Estuary in Physical Model Test

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China Ocean Engineering 2017年第5期31卷 624-630页

作者： jiao Zeng-xiang Dou Xi-ping ZHENG Jin-hai ZHANG Xin-zhou GAO Xiang-yu Nanjing Hydraulic Research Institute College of Harbor Coastal and Offshore EngineeringHohai University Key Laboratory of Port Waterway and Sedimentation Engineering of the Ministry of Transport

Widely applied in maintaining estuarial waterway depth, the spur dike has played an important role in currents and sediment exchange between channel and shoal and sediment back-silting in the channel. Through establishing a generalized physical model at a bifurcated estuary and conducting current tests under the joint action of runoff and tide, the influence of the spur dike length on current exchange between channel and shoal is analyzed. Results show that when the spur dike length reaches a certain value, the direction of the flow velocity shear front between the channel and shoal will change. The longer the spur dike, the larger the transverse fluctuating velocity at the peak of flood in the channel shoal exchange area, while the transport of the transverse hydrodynamics is obvious in the process of flood. There is an optimum length of spur dike when the shear stress in the channel and the longitudinal velocity in flood and ebb reach the maximum, and the flow velocity will decrease when the spur dike length is smaller or larger than the optimum. For a certain length of spur dike, the larger the channel shoal elevation difference, the larger the peak longitudinal flow velocity in the middle of the navigation channel in flood and ebb. However, the transverse flow velocity will first decrease and then increase. The transverse transportation is obvious when the channel shoal elevation difference increases.

关键词： spur dike hydrodynamics flow velocity channel shoal exchange physical model

Inositol-requiring enzyme 1α is required for gut development in Xenopus lavies embryos

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World Journal of Gastroenterology 2013年第2期19卷 227-234页

作者： Jing Guo Xin-Xin Li jiao-jiao Feng Chen-Yang Yin XueJun Wang ning Wang Li Yuan Department of Biochemistry and Molecular Biology Nanjing Medical University

AIM:To investigate the role of inositol-requiring enzyme 1α(IRE1α) in gut development of Xenopus lavies ***:Xenopus embryos were obtained with in vitro fertilization and cultured in 0.1 × *** and half nanogram of IRE1α,1 ng of IRE1α-GR mRNA,1 ng of IRE1αΔC-GR mRNA,and 50 ng of IRE1α morpholino oligonucleotide(MO) or XBP1(C)MO were injected into four blastomeres at 4-cell stage for scoring the phenotype and marker gene *** rescue the effect of IRE1α MO,1 ng of IRE1α-GR mRNA was coinjected with 50 ng of *** the activation of the GR-fusion proteins,dexamethasone was prepared as 5 mmol/L stock solutions in 100% ethanol and applied to the mRNA injected embryos at desired stages in a concentration of 10 μmol/L in 0.1 × *** were kept in dexamethasone up to stage ***-mount in situ hybridization was used to determine specific gene expression,such as IRE1α,IRE1β,Xbra and Xsox17α.IRE1α protein expression during Xenopus embryogenesis was detected by Western ***:In the whole-mount in situ hybridization analysis,xenopus IRE1α and IRE1β showed quite different expression pattern during tadpole *** relatively higher expression of IRE1α was observed in the pancreas,and significant transcription of IRE1β was found in the ***1α protein could be detected at all developmental stages analyzed,from stage 1 to stage ***-of-function assay showed that IRE1α mRNA injected embryos at tailbud stage were nearly normal and the expression of the pan-mesodermal marker gene Xbra and the endodermal gene Xsox17α at stage 10.5 was not significantly changed in embryos injected with IRE1α mRNA as compared to uninjected control *** at tadpole stage,the embryos injected with IRE1α-GR mRNA did not display overt phenotype,such as gut-coiling ***-of-function assay demonstrated that the IRE1α MO injected embryos were morphologically normal before the tailbud *** did not observe a significant change of mesodermal and end

关键词： Inositol-requiring enzyme 1α XBP1 Xenopus lavies Gut Development

Coupling relationship between multicomponent recovery of rare earth tailings

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Rare Metals 2017年第3期36卷 220-228页

作者： Yue Zhang hai Lin Ying-Bo Dong Xiao-Fang Xu Xin Wang Yue-jiao Gao School of Civil and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Key Laboratory of High-Efficient Mining and Safety of Metal Mines Ministry of EducationUniversity of Science and Technology BeijingBeijing 100083China

About 90 % rare earth minerals and many other valuable minerals are heaped as iron tailings without comprehensive utilization. In order to comprehensively recover these valuable minerals, in a view of the valuable ore type of Baotou Steel tailing and embedded features, valuable components flow and their respective recovery coupling relationship in beneficiation flowsheet were ana- lyzed; process flows and parameters which could give consideration to four kinds of components were deter- mined. TFe, rare earth oxide （REO）, niobium and fluorite recoveries could reach 72.70 %, 81.84 %, 78.58 % and 60.18 % in low-intensity/high-intensity magnetic separa- tion, respectively. High-intensity magnetic concentration was treated by REO direct flotation; the recovery is 75.43 %, on the base of which Fe could be separated completely from Nb. The underflow was treated by reduction roasting-low-intensity magnetic separation. And the relationship between the recoveries of these valuable components was also discussed.

关键词： Rare earth tailings Recovery Couplingrelationship