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Overlapping infections of Mycobacterium canariasense and Nocardia farcinica in an immunocompetent patient:A case report

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World Journal of Clinical Cases 2024年第12期12卷 2079-2085页

作者： hai-Yan Huang Kun-Peng Bu jin-Wei Liu jing Wei Department of Comprehensive Internal Medicine The Affiliated Cancer Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Doppler Ultrasound The Second Nanning People's HospitalNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent *** canariasense(***)was first reported as an opportunistic pathogen in 2004,but there have been very few case reports since *** is a genus of aerobic and Gram-positive bacilli,and these species are also opportunistic pathogens and in the Mycobacteriales *** methods for diagnosis of NTM are *** next-generation sequencing(mNGS)can rapidly detect many pathogenic microorganisms,even rare *** NTM and Nocardia infections occur in immunocompromised patients with atypical clinical *** are no previous reports of infection by *** and Nocardia farcinica(***),especially in immunocompetent *** case report describes an immunocompetent 52-year-old woman who had overlapping infections of ***,***,and Candida parapsilosis(***)based on *** SUMMARY A 52-year-old woman presented with a productive cough and chest pain for 2 wk,and recurrent episodes of moderate-grade fever for 1 *** received antibiotics for 1 wk at a local hospital,and experienced defervescence,but the productive cough and chest pain *** collected samples of a lung lesion and alveolar lavage fluid for *** lung tissue was positive for ***,***,and ***,and the alveolar lavage fluid was positive for *** diagnosis was pneumonia,and application of appropriate antibiotic therapy cured the *** Etiological diagnosis is critical for patients with infectious *** can identify rare and novel pathogens,and does not require a priori knowledge.

关键词： Overlapping infection Mycobacterium canariasense Nocardia farcinica Metagenomic next-generation sequencing technology Case report

Development of lithium-free P2-type high-sodium content cathode materials with enhanced cycle and air stability for sodium-ion batteries

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Rare Metals 2024年第1期43卷 113-123页

作者： jin-Lv Tian Lin-Rong Wu hai-Jun Zhao Shou-Dong Xu Liang Chen Ding Zhang Xiao-Chuan Duan College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China

The effect of partial substitution of Mg for Ni on a high-sodium and lithium-free layered P2-type Na_(45/54)Mg_(6)/_(54)Ni_(12/54)Mn_(34/54)O_(2) cathode with high initial Coulombic efficiency and excellent cyclic stability has been investigated in this *** on the crystal structural analysis,the Mg doping can retain the P2 structure up to 4.3 V,thus restraining the detrimental phase transformation of P2-02during the Na-ion intercalation/deintercalation ***,the obtained Mg-doped P2-type cathode exhibits a reversible specific capacity of 109 mAh·g^(-1) at 0.1C between 2.0 and 4.3 V and a retention rate of 81.5% after 200cycles at *** addition,the full cell consisting of Mg-doped P2-type cathode and hard carbon anode shows a capacity retention rate of 85.6% after 100 *** study provides new insight into the development of durable cathode materials for sodium-ion batteries.

关键词： Sodium-ion batteries Cathode material High sodium content Air stability

Two-dimensional conjugated coordination polymer monolayer as anode material for lithium-ion batteries:A DFT study

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Chinese Chemical Letters 2024年第6期35卷 180-184页

作者： Xin-Tong Zhao jin-Zhi Guo Wen-Liang Li jing-Ping Zhang Xing-long Wu MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun 130024China Faculty of Chemistry Northeast Normal UniversityChangchun 130024China Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province Gannan Normal UniversityGanzhou 341000China

Nowadays,lithium-ion batteries(LIBs)play a crucial role in modern society in the aspect of portable electronic devices and large-scale smart ***,the current performance of lithium-ion batteries has been unable to meet the growing expectations of society and scientific ***,we have synthetically investigated availability of 2D Ni-TABQ monolayer as anode based on DFT for LIBs *** findings have demonstrated that 2D Ni-TABQ monolayer is a semiconductor with a small band gap of 0.2 eV,which suggest that the electronic property of 2D Ni-TABQ monolayer would take place an evident shift from semiconductor property to metallic property after Li ***,we checked the stability of 2D Ni-TABQ monolayer and investigated the viability of exfoliation from bulk multilayer Ni-TABQ to form 2D Ni-TABQ monolayer in the light of exfoliation energy and binding *** continuously studied electrochemical properties of 2D Ni-TABQ monolayer with respect of theoretical specific capacity,Li-ion diffusion barriers and open-circuit *** the charging process,2D Ni-TABQ monolayer can achieve a high specific capacity of 722 m Ah/g with an open-circuit voltage range from 1.12 V to 0.22 *** aforementioned results make the 2D Ni-TABQ monolayer a promising anode for LIBs.

关键词： The first principles Density functional theory Lithium-ion battery Anode material Two-dimensional material

Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia

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Genes & Diseases 2024年第5期11卷 105-108页

作者： Liang Zhou Youyou Li Jiaren Li Hanyu Yao jin Huang Cheng Li long Wang Department of Urology The Third Xiangya Hospital of Central South UniversityChangshaHunan 410013China

In aging males,benign prostatic hyperplasia(BPH)is a chronic pathological process that primarily causes lower urinary tract *** to histopathology,BPH is caused by an imbalance between cell death and proliferation.1 However,the exact pathophysiology remains *** is a newly discovered form of programmed cell *** cell morphology is characterized primarily by the reduction or disappearance of mitochondrial cristae and mitochondrial shrinkage.2,3 Competing endogenous RNAs(ceRNAs)are important regulators of many biological processes and have been involved in various diseases.

关键词： prostatic endogenous BPH

Flexible and multifunctional triboelectric nanogenerator based on liquid metal/polyvinyl alcohol hydrogel for energy harvesting and self-powered wearable human-machine interaction

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Rare Metals 2024年第3期43卷 1186-1196页

作者： Hou-Wang Zhou Cong Zhao Ze-Yu Zhao Jun-Chen Jiang Hui-Le jin Shun Wang Shuang Pan Min-Yi Xu Yi-Huang Chen hai-Ming jin Department of Orthopaedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou325027China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou325035China Dalian Key Laboratory of Marine Micro/Nano Energy and Self-Powered Systems Marine Engineering CollegeDalian Maritime UniversityDalian116026China

Hydrogel-based triboelectric nanoge nerator(TENG)has a promising applied prospect in wearable electronic ***,its low performance,poor stability,insufficient recyclability and inferior self-healing seriously hinder its ***,we report a robust route to a liquid metal(LM)/polyvinyl alcohol(PVA)hydrogel-based TENG(LP-TENG).Owing to the intrinsically liquid feature of conductive LM within the flexible PVA hydrogel,the as-prepared LP-TENG exhibited comprehensiye advantages of adaptability,biocompatibility,outstanding electrical performance,superior stability,recyclability and diverse applications,which were unattainable by traditional ***,the LP-TENG delivered appealing open circuit voltage of 250 V,short circuit current of 4μA and transferred charge of 120 nC with high stability,outperforming most advanced TENG *** LP-TENG was successfully employed for versatile applications with multifunctionality,including human motion detection,handwriting recognition,energy collection,message transmission and human-machine *** work presents significant prospects for crafting advanced materials and devices in the fields of wearable electronics,flexible skin and smart robots.

关键词： Liquid metal Hydrogel Wearable TENG Multifunctionality Human-machine interaction

Quercetin Alleviates Lipopolysaccharide-Induced Cardiac Inflammation via Inhibiting Autophagy and Programmed Cell Death

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Biomedical and Environmental Sciences 2024年第1期37卷 54-70页

作者： YU jin hai HU Guo Liang GUO Xiao Quan CAO Hua Bin XIA Zhao Fei AMIN Buhe Jiangxi Provincial Key Laboratory for Animal Health Institute of Animal Population HealthCollege of Animal Science and TechnologyJiangxi Agricultural UniversityNanchang 330045JiangxiChina Internal Medicine Laboratory Department of Veterinary Clinical MedicineCollege of Veterinary MedicineChina Agricultural UniversityBeijing 100091China Department of Cancer Surgery Beijing Shijitan Hospital Affiliated with Capital Medical UniversityBeijing 100038China

Objective The aim of this study is to explore the potential modulatory role of quercetin against Endotoxin or lipopolysaccharide(LPS)induced septic cardiac *** Specific pathogen-free chicken embryos(n=120)were allocated untreated control,phosphate buffer solution(PBS)vehicle,PBS with ethanol vehicle,LPS(500 ng/egg),LPS with quercetin treatment(10,20,or 40 nmol/egg,respectively),Quercetin groups(10,20,or 40 nmol/egg).Fifteenday-old embryonated eggs were inoculated with abovementioned solutions via the allantoic *** embryonic day 19,the hearts of the embryos were collected for histopathological examination,RNA extraction,real-time polymerase chain reaction,immunohistochemical investigations,and Western *** They demonstrated that the heart presented inflammatory responses after LPS *** LPS-induced higher mRNA expressions of inflammation-related factors(TLR4,TNFα,MYD88,NF-κB1,IFNγ,IL-1β,IL-8,IL-6,IL-10,p38,MMP3,and MMP9)were blocked by quercetin with three *** significantly decreased immunopositivity to TLR4 and MMP9 in the treatment group when compared with the LPS *** significantly decreased protein expressions of TLR4,IFNγ,MMP3,and MMP9 when compared with the LPS *** treatment prevented LPS-induced increase in the mRNA expression of Claudin 1 and ZO-1,and significantly decreased protein expression of claudin 1 when compared with the LPS *** significantly downregulated autophagyrelated gene expressions(PPARα,SGLT1,APOA4,AMPKα1,AMPKα2,ATG5,ATG7,Beclin-1,and LC3B)and programmed cell death(Fas,Bcl-2,CASP1,CASP12,CASP3,and RIPK1)after LPS *** significantly decreased immunopositivity to APOA4,AMPKα2,and LC3-II/LC3-I in the treatment group when compared with the LPS *** significantly decreased protein expressions of AMPKα1,LC3-I,and *** significantly decreased the protein expression to CASP1 and CASP3 by immunohistochemical investigation or

关键词： Quercetin Lipopolysaccharide Inflammation Autophagy Programmed cell death Myocardiocytes permeability

Effects of oral probiotics on inflammation and intestinal function in adult patients after appendectomy:Randomized controlled trial

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1371-1376页

作者： Ke Lan Ke-Rui Zeng Fu-Rui Zhong Sheng-jin Tu jin-long Luo Shi-long Shu Xue-Feng Peng Hua Yang Kai Lu Department of General Surgery Zigong Fourth People's HospitalZigong 643000Sichuan ProvinceChina

BACKGROUND Appendectomy is an acute abdominal surgery that is often accompanied by severe abdominal *** probiotics are one of the postoperative treatments for rapid ***,there is a lack of prospective studies on this topic after *** To investigate whether the postoperative probiotics can modulate the inflammatory response and restore intestinal function in patients following *** This was a prospective,randomized trial.A total of 60 emergency patients were randomly divided into a control group(n=30)and a probiotic group(n=30).Patients in the control group started to drink some water the first day after surgery,and those in the probiotic group were given water supplemented with Bacillus licheniformis capsules for 5 consecutive days *** indices of inflammation and postoperative conditions were recorded,and the data were analyzed with RStudio 4.3.2 *** A total of 60 participants were *** with those in the control group,the C-reactive protein(CRP),interleukin 6 and procalcitonin(PCT)levels were significantly lower in the probiotic group at 2 d after surgery(P=2.224e-05,P=0.037,and P=0.002,respectively,all P<0.05).This trend persisted at day 5 post-surgery,with CRP and PCT levels remaining significantly lower in the probiotic group(P=0.001 and P=0.043,both P<0.05).Furthermore,probiotics0.028,both P<0.05).CONCLUSION Postoperative oral administration of probiotics may modulate the gut microbiota,benefit the recovery of the early inflammatory response,and subsequently enhance recovery after appendectomy.

关键词： Probiotics Gut microbiota Appendectomy Inflammatory markers Intestinal function Enhanced recovery after surgery Postsurgical infections

Laser powder bed fusion of NiTiFe shape memory alloy via premixed powder:microstructural evolution,mechanical and functional properties

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Rare Metals 2024年第5期43卷 2300-2316页

作者： Bo Yuan jin-Guo Ge Liang Zhang Hong-Jun Chen long-Sha Wei Yu-Duo Zhou Run-Hua Song Institute of Intelligent Manufacturing Technology Shenzhen PolytechnicShenzhen 518055China School of Mechanical and Electrical Engineering Guilin University of Electronic TechnologyGuilin 541004China Guangdong Advanced Polymer Composite Engineering Technology Research Center Shenzhen Academy of Aerospace TechnologyShenzhen 518057China Jihua Laboratory Testing Center Jihua LaboratoryFoshan 528000China

High-cost pre-alloyed powder is the bottleneck problem that limits the widespread application of additivemanufactured shape memory *** this work,the lowcost ternary NiTiFe shape memory alloy is fabricated by laser powder bed fusion(LPBF)technique via mechanically mixed pre-alloy NiTi powder and varying contents pure Fe powder(1,2,3 wt%).All NiTiFe alloys show a relative density of up to 99.8%by optimizing the LPBF processing *** to the heterogeneous nucleation effect of micron-sized Fe particles,both grain refinement and texture weakening are generated in the NiTiFe alloys,accompanied by the reduction of dislocation *** the room-temperature mechanical properties,the NiTi-3Fe alloy shows the highest microhardness of HV370,but the fracture strength and elongation reduce to1701 MPa and 23%*** evolution of mechanical properties is attributed to the high internal defects,low dislocation density and the incoherent ***,the NiTi-3Fe alloy shows the quasi-linear superelasticity behavior;the superelastic recoverable strain of NiTi-1Fe and NiTi-2Fe decreased with the increase in Fe *** study provided a new-fangled insight for the development of multi-component NiTi-based shape memory alloys by additive manufacturing.

关键词： Additive manufacturing Shape memory alloy Metal matrix composite Microstructure Mechanical properties

A novel method for extracting and optimizing the complex permittivity of paper-based composites based on an artificial neural network model

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Science China Technological Sciences 2024年第10期67卷 3190-3204页

作者： XIA ChenBin SHEN JunYi LIAO ShaoWei WANG Yi HUANG ZhengSheng XUE Quan TANG Min long jin HU Jian School of Light Industry and Engineering South China University of Technology School of Electronic and Information Engineering South China University of Technology

Measuring the complex permittivity of ultrathin, flexible materials with a high loss tangent poses a substantial challenge with precision using conventional methods, and verifying the accuracy of test results remains difficult. In this study, we introduce a methodology based on a back-propagation artificial neural network(ANN) to extract the complex permittivity of paper-based composites(PBCs). PBCs are ultrathin and flexible materials exhibiting considerable complex permittivity and dielectric loss tangent. Given the absence of mature measurement methods for PBCs and a lack of sufficient data for ANN training, a mapping relationship is initially established between the complex permittivity of honeycomb-structured microwave-absorbing materials(HMAMs, composed of PBCs) and that of PBCs using simulated data. Leveraging the ANN model, the complex permittivity of PBCs can be extracted from that of HMAMs obtained using standard measurement. Subsequently, two published methods are cited to illustrate the accuracy and advancement of the results obtained using the proposed approach. Additionally, specific error analysis is conducted, attributing discrepancies to the conductivity of PBCs, the homogenization of HMAMs, and differences between the simulation model and actual objects. Finally, the proposed method is applied to optimize the cell length parameters of HMAMs for enhanced absorption performance. The conclusion discusses further improvements and areas for extended research.

关键词： paper-based composite honeycomb complex permittivity artificial neural networks inverse modeling

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