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Optimizing the key parameter to accelerate the recovery of AMOC under a rapid increase of greenhouse gas forcing

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 39-45页

作者： Haolan Ren Fei Zheng Tingwei cao Qiang Wang International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina College of Oceanography Hohai UniversityNanjingChina CAS Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning Circulation(AMOC)plays a central role in long-term climate variations through its heat and freshwater transports,which can collapse under a rapid increase of greenhouse gas forcing in climate *** studies have suggested that the deviation of model parameters is one of the major factors in inducing inaccurate AMOC *** this work,with a low-resolution earth system model,the authors try to explore whether a reasonable adjustment of the key model parameter can help to re-establish the AMOC after its *** a new optimization strategy,the extra freshwater flux(FWF)parameter is determined to be the dominant one affecting the AMOC’s *** traditional ensemble optimal interpolation(EnOI)data assimilation and new machine learning methods are adopted to optimize the FWF parameter in an abrupt 4×CO_(2) forcing experiment to improve the adaptability of model parameters and accelerate the recovery of *** results show that,under an abrupt 4×CO_(2) forcing in millennial simulations,the AMOC will first collapse and then re-establish by the default FWF parameter ***,during the parameter adjustment process,the saltier and colder sea water over the North Atlantic region are the dominant factors in usefully improving the adaptability of the FWF parameter and accelerating the recovery of AMOC,according to their physical relationship with FWF on the interdecadal timescale.

关键词： Recovery of AMOC 4×CO_(2)forcing Key parameter Parameter estimation Data assimilation Machine learning

Manual acupuncture at the SJ5(Waiguan) acupoint shows neuroprotective effects by regulating expression of the anti-apoptotic gene Bcl-2

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Neural Regeneration Research 2016年第2期11卷 305-311页

作者： Dong lin Li-li lin Kyle Sutherland Chuan-hai cao College of Acupuncture Fujian University of Traditional Chinese Medicine Department of Neurosurgery and Brain Repair Morsani College of Medicine University of South Florida

Acupuncture at the SJ5（Waiguan） acupoint has neuroprotective effects in cerebral infarction, but the underlying mechanism remains poorly understood. Here, we analyzed gene expression in healthy rat cerebellum using a pathway-focused DNA microarray to screen 113 genes associated with 18 signal transduction pathways. After 20 minutes of acupuncture at SJ5, the expression of Bcl-2 and Birc1 b m RNA was markedly increased. This was confirmed by real-time reverse transcription PCR. Furthermore, western blot analysis showed that Bcl-2 protein expression remained high in the cerebellum until at least 2 hours after cessation of acupuncture. These findings indicate that acupuncture at SJ5 exerts neuroprotective effects by regulating the expression of anti-apoptotic gene Bcl-2.

关键词： nerve regeneration neuroprotection acupuncture SJ5 cerebellum apoptosis signal transduction Bcl-2 neural regeneration

Unraveling post-growth mechanisms of monolayer CsPbBr3 nanocubes:Laser-enhanced transformations and cathodoluminescence-electron microscopy correlations

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Journal of Energy Chemistry 2025年第1期100卷 146-156页

作者： Mingxing Li Xiaoge Wang Xiaofan cao Zhiqun He Chunjun Liang Mingxing Chen Jing Ju Fangtian You Key Laboratory of Luminescence and Optical Information Ministry of Education Institute of Optoelectronic Technology Beijing Jiaotong University Beijing National Laboratory for Molecular Sciences (BNLMS) College of Chemistry and Molecular Engineering Peking University

Lead-halide perovskite nanoparticles（LHP NPs） are highly promising materials for next-generation displays and solid-state lighting due to their exceptional optical properties. However, their inherent instability presents a significant challenge. Recent advances have demonstrated that optoelectronic devices based on monolayer nanoparticle films exhibit both high luminescence efficiency and long-term *** research demonstrates that mobility limitations and anisotropic alignments in CsPbBr3nanocube monolayer films are key to their stabilization, hindering spontaneous growth through face-to-face fusion and resulting in the formation of connecting necks in a diagonal direction. Introducing laser irradiation confirmed this by significantly accelerating nanocubes growth, increasing mobility, and enhancing local structural ordering, leading to larger and more regularly shaped nanosheets. Fourier transform infrared spectroscopy and energy dispersive spectroscopy line-scan analyses indicated that laser irradiation did not disrupt the ligand structure. Transmission electron microscopy and correlative cathodoluminescence electron microscopy revealed the effects of post-growth and heterogeneous structures, including enhanced luminescence and inhomogeneous intensity in the nanosheets. These findings deepen the understanding of the post-growth mechanism of monolayer nanoparticles and the structure-emission correlation and highlight the unique role of laser irradiation in directing the formation of well-defined and regular nanostructures.

关键词： Post-growth mechanism Heterogeneous structure Single-particle spectroscopy Laser irradiation

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi Xu Junqiu Jia Rui Mao Xiang cao Yun Xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

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鲜切菜工艺条件对产品质量的影响

食品科技 2003年第12期28卷 33-35页

作者：李海林曹卫华潘夏生苏州农业职业技术学院苏州215008 苏州市农业局苏州215006

研究鲜切菜加工工艺条件对产品质量的影响。结果表明选择适宜的蔬菜原料及其品种、合理切割、充分洗涤和控水,40mm LDPE薄膜包装,5℃以下温度管理能有效地控制鲜切菜的质量。

关键词：鲜切菜工艺条件质量

Mineral transition and formation mechanism of calcium aluminate compounds in cao-Al2O3-Na2O system during high-temperature sintering

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International Journal of Minerals,Metallurgy and Materials 2020年第7期27卷 924-932页

作者： hai-yan Yu Xiao-lin Pan Yong-pan Tian Gan-feng Tu School of Metallurgy Northeastern UniversityShenyang 110819China

The mineral transition and formation mechanism of calcium aluminate compounds in cao-Al2O3-Na2O system during the hightemperature sintering process were systematically investigated using DSC-TG,XRD,SEM-EDS,FTIR,and Raman spectra,and the crystal structure of Na4Ca3(AlO2)10 was also simulated by Material Studio *** results indicated that the minerals formed during the sintering process included Na4Ca3(AlO2)10,cao·Al2O3,and 12 cao·7 Al2O3,and the content of Na4Ca3(AlO2)10 could reach 92 wt%when sintered at 1200°C for 30 *** main formation stage of Na4Ca3(AlO2)10 occurred at temperatures from 970 to 1100°C,and the content could reach82 wt%when the reaction temperature increased to 1100°*** crystal system of Na4Ca3(AlO2)10 was tetragonal,and the cells preferred to grow along crystal planes(110)and(210).The formation of Na4Ca3(AlO2)10 was an exothermic reaction that followed a secondary reaction model,and its activation energy was 223.97 kJ/mol.

关键词： calcium aluminate sodium oxide crystal structure formation kinetics sintering

PREDICTION OF LOADING DISTRIBUTION AND HYDRODYNAMIC MEASUREMENTS FOR PROPELLER BLADES IN A RIM DRIVEN THRU-STER

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Journal of Hydrodynamics 2012年第1期24卷 50-57页

作者： cao Qing-ming HONG Fang-wen TANG Deng-hai HU Fang-lin LU lin-zhang China Ship Scientific Research Centre Wuxi 214082China

This article presents an approach which employs a commercial Reynolds-Averaged Navier-Stokes（RANS）solver to predict the steady wake field and loading distributions for a rim driven *** different cases of propeller blades are chosen to be calculated with the presented *** propeller blade radial circulation and chordwise circulation density distributions are *** maximum radial circulation is found at the blade tip,which is different from conventional shaft driven *** numerical results indicate that there is no tip leakage vortex in rim driven *** there exist the tip joint vortex and the root region *** characteristics are calculated by taking rim surface effect into *** the predicted results the second case in this paper is selected as the final one to perform hydrodynamic *** calculation results with empirical rim surface corrections are compared with the *** shows that the developed numerical method can well predict hydrodynamic performances of the rim driven thruster.

关键词： rim driven thruster Reynolds-Averaged Navier-Stokes(RANS)solver wake field radial circulation chordwise circulation density hydrodynamic experiment

Novel Brфnsted Acidic Ionic Liquid Based on a Cyclic Guanidinium Cation:a Green,Efficient,and Recyclable Dual Slovent-catalyst System for Fisher Esterification

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Chemical Research in Chinese Universities 2007年第6期23卷 665-668页

作者： GUO Xu DUAN hai-feng SUN hai cao Jun-gang lin Ying-jie Department of Organic Chemistry College of Chemistry Jilin University Changchun 130012 P. R. China

A novel BrФnsted acidic ionic liquid（IL） based on the cyclic guanidinium cation has been synthesized. This IL, as a strong BrФnsted acid catalyst or solvent, shows high catalytic activity and biphsaic behavor in the esterifications of carboxylic acids and alcohols. The produced esters as a separate phase can be conveniently decanted out from the IL and the IL is recyclable without any loss of catalytic activity.

关键词： BrФnsted acid Ionic liquid Guanidinium Fisher esterification

Electrocatalytic cleavage of a lignin β-O-4 model compound and coupling with nitrogen-containing aromatics using Prussian blue analogue-derived nickel–cobalt spinel

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Journal of Energy Chemistry 2025年第1期100卷 628-636页

作者： Yi Qi Xueying Chen Bowen Liu Xuliang lin Xueqing Qiu Yanlin Qin Guangdong Provincial Key Laboratory of Plant Resources Biorefinery School of Chemical Engineering and Light Industry Guangdong University of Technology Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Guangdong Basic Research Center of Excellence for Ecological Security and Green Development Guangdong University of Technology

Electrochemical conversion of lignin for the production of high-value heterocyclic aromatic compounds has great *** demonstrate the targeted synthesis and cation modulation of NiCo2O4spinel nanoboxes,synthesized via cation exchange and calcination *** catalysts exhibit excellent efficacy in the electrocatalytic conversion of lignin model compounds,specifically 2-phenoxy-1-phenylethanol,into nitrogen-containing aromatics,achieving high conversion rates and *** catalysts were synthesized via a cation exchange and calcination oxidation process,using Prussian blue nanocubes as *** porous architecture and polymetallic composition of the NiCo2O4spinel demonstrated superior performance in electrocatalytic oxidative coupling,achieving a 99.2 wt%conversion rate of the 2-phenoxy-1-phenylethanol with selectivities of 37.5 wt%for quinoline derivatives and 31.5 wt%for *** innovations include the development of a sustainable one-pot synthesis method for quinoline derivatives,the elucidation of a multistage reaction pathway involving cao bond cleavage,hydroxyaldol condensation,and CAN bond formation,and a deeper mechanistic understanding derived from DFT *** work establishes a new strategy for lignin valorization,offering a sustainable route to produce high-value nitrogen-containing aromatics from renewable biomass under mild conditions,without the need for additional reagents.

关键词： Spinel Biomass valorization Electrocatalysis Lignin oxidation Coupling