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Creatine Pyruvate Enhances Lipolysis and Protein Synthesis in Broiler Chicken

Agricultural Sciences in China 2011年第12期10卷 1977-1985页

作者： CHEN Juan MA hai-tian wang Man KONG Yi-li ZOU Si-xiang Key Laboratory of Animal Physiology ＆ Biochemistry College of Veterinary Medicine Nanjing Agricultural University Nanjing 210095 P.R. China

To assess the effects ofcreatine pyruvate （Cr-Pyr） on lipid and protein metabolism in broiler chickens, a total of 400 1-day-old male birds （Aconred） were randomly allocated to four groups, with each group replicating four times and each replicate involving 25 birds. The broilers were provided with a commercial diet supplemented with Cr-Pyr at 0, 1, 5, or 10% of the diet, respectively, for a period of 3 wk ad libitum （from 22 to 42 d）. In the present study, body weight （BW） and average daily gain （ADG） of broilers decreased in 10% Cr-Pyr group （P〈0.01）, whereas the relative leg and pectoral muscle weights were significantly higher than they were in the control group （P〈0.05）. 5 or 10% Cr-Pyr of diets decreased the abdominal fat rate （AFR, abdominal fat/live weight） of the broilers. The serum or hepatic triglyceride （TG） concentrations were significantly lower in the 5 and 10% groups （P〈0.01）. In contrast, Cr-Pyr caused a marked increase in the serum nonesterified fatty acid （NEFA）, high-density lipoprotein cholesterol （HDL-C） and creatine kinase （CK） concentrations （P〈0.01）. Supplementation with Cr-Pyr （5 and 10%） in the diet also increased glucagons （GLU）, insulin （INS） or leptin （LEP） contents （P〈0.01）. The expression of hepatic peroxisomal proliferators-activated receptor α （PPAR-α） and carnitine palmitoyl transferase-I （CPT-I）, muscle insulin-like growth factor I （IGF-I） were significantly elevated and myostatin mRNA level was reduced in the 5 and 10% groups （P〈0.05）. It was found that supplementation with 5% Cr-Pyr improves both lipid and protein metabolism by regulating various metabolic parameters of broilers, while not adversely affects growth performance in broiler chickens.

关键词： creatine pyruvate (Cr-Pyr) lipid metabolism protein metabolism liver muscle broiler chickens

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Detection of astrophysical gravitational wave sources by tianQin and LISA

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Science China(Physics,Mechanics & Astronomy) 2024年第5期67卷 123-163页

作者： Alejandro Torres-Orjuela Shun-Jia Huang Zheng-Cheng Liang Shuai Liu hai-tian wang Chang-Qing Ye Yi-Ming Hu Jianwei Mei MOE Key Laboratory of tian Qin Mission Tian Qin Research Center for Gravitational PhysicsSchool of Physics and AstronomyFrontiers Science Center for Tian QinGravitational Wave Research Center of CNSASun Yat-Sen University(Zhuhai Campus)Zhuhai 519082China Department of Physics The University of Hong KongHong Kong 999077China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing100871China

tianQin and LISA are space-based laser interferometer gravitational wave(GW)detectors planned to be launched in the *** detectors will detect low-frequency GWs around 10^(-2)Hz;however,tian Qin is more sensitive to frequencies above this common sweet-spot while LISA is more sensitive to frequencies below 10^(-2)***,tian Qin and LISA will be able to detect the same sources but with different accuracy depending on the source and its *** consider some of the most important astrophysical sources—massive black hole binaries,stellar-mass black hole binaries,double white dwarfs,extreme mass ratio inspirals,light and heavy intermediate mass ratio inspirals,as well as the stochastic gravitational background of astrophysical origin—that tian Qin and LISA will be able to *** each of these sources,we analyze how far they can be detected(detection distance)and how well their parameters can be measured(detection accuracy)using a Fisher Matrix *** compare the results obtained by the three detection scenarios(tian Qin alone,LISA alone,and joint detection by LISA and tian Qin)highlighting the gains from joint detection as well as the contribution of tian Qin and LISA to a combined study of astrophysical *** particular,we consider the different orientations,lifetimes,and duty cycles of the two detectors to explore how they can give a more complete picture when working together.

关键词： wave extreme stochastic

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Potential dependence in electrocatalysis: a theoretical perspective

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Science China Chemistry 2025年第1期 21-25页

作者： Leyu Liu Zhaoming Xia Zeyu wang Yinjuan Chen hai Xiao Department of Chemistry Tsinghua University Fundamental Science Center of Rare Earths Ganjiang Innovation Academy Chinese Academy of Sciences Key Laboratory of Advanced Catalytic Materials and Technology Advanced Catalysis and Green Manufacturing Collaborative Innovation Center Changzhou University

Electrocatalysis is a key technology for the new energy era and sustainable development, serving as the interface for interconversion of electrical and chemical energies, which spans a wide spectrum of applications in sustainable energy and environmental engineering. Electrocatalytic reactions including electrochemical CO2reduction reaction （eCO2RR）, hydrogen evolution reaction （HER）, and oxygen evolution/reduction reactions （OER/ORR）, hold essential promise for renewable energy technologies as well as complement the biogeochemical carbon and oxygen cycles.

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多选择NTU结构对策下的社会稳定核心

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运筹与管理 2017年第2期26卷 49-56页

作者：田海燕王志巍郑小伟张刚西北工业大学理学院应用数学系陕西西安710072 河北师范大学数学与信息科学学院河北石家庄050024

本文研究了多选择情形下NTU结构对策及其社会稳定核心的理论和应用。定义了多选择NTU结构对策的转移率规则和支付依赖平衡性质,给出了K-K-M-S定理在多选择NTU结构对策下的一个扩展形式,并用扩展后的K-K-M-S定理证明了如果转移率规则包... 详细信息

本文研究了多选择情形下NTU结构对策及其社会稳定核心的理论和应用。定义了多选择NTU结构对策的转移率规则和支付依赖平衡性质,给出了K-K-M-S定理在多选择NTU结构对策下的一个扩展形式,并用扩展后的K-K-M-S定理证明了如果转移率规则包含某些力量函数值,且多选择NTU结构对策关于转移率规则是支付依赖平衡的,则多选择NTU结构对策的社会稳定核心是非空的。

关键词：多选择NTU对策结构对策核心 K—K—M—S定理支付依赖平衡

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产前死胎危险因素的病例对照研究（英文）

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中山大学学报（医学科学版） 2016年第6期37卷 956-960,F0003页

作者：李珠玉陈海天王惠子王子莲中山大学附属第一医院妇产科广东广州510080

摘要：【目的】探讨产前死胎的相关危险因素。【方法】收集2011年1月-2015年12月中山大学附属第一医院收治的孕≥20周产前死胎病例74例作为死胎组，按1：2的比例随机选取同期148例单胎活产分娩作为对照组。回顾病例资料，比较两组的临... 详细信息

摘要：【目的】探讨产前死胎的相关危险因素。【方法】收集2011年1月-2015年12月中山大学附属第一医院收治的孕≥20周产前死胎病例74例作为死胎组，按1：2的比例随机选取同期148例单胎活产分娩作为对照组。回顾病例资料，比较两组的临床特点，分析产前死胎的危险因素。采用t检验、卡方检验及Logistic回归分析进行统计学处理。【结果】无规范产检、流动人口、大专以下学历、胎动异常在死胎组的比率均高于对照组，两组相比差异均有统计学意义（P值分别为0．000、0．004、0．024、0．000），而年龄、孕前体质量指数、产次、稽留流产史及死胎史两组差异无统计学意义；妊娠期高血压疾病在死胎组的比率高于对照组，差异有统计学意义（P=0．000）。将有统计学差异的变量纳入单因素Logistic回归分析．结果发现．无规范产检、流动人口、大专以下学历、胎动异常及妊娠期高血压疾病者发生死胎的风险均增加，其OR值及95％C1分别为4．65（2．36—9．18）、2．46（1．32—4．61）、2．43（1．10—5．36）、211．32（47．64—937．30）、6．67（2．30—19．35）。【结论】无规范产检、流动人口、大专以下学历、胎动异常及妊娠期高血压疾病是产前死胎危险因素。加强公众尤其是流动人口健康教育及围产保健意识，及早发现、治疗妊娠期高血压疾病等高危妊娠可能有助于降低产前死胎的发生。

关键词：死胎危险因素围产保健

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Multi-receptive field interaction network for shape from polarization

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Science China(Information Sciences) 2025年第1期 394-395页

作者： Yini PENG Rui LIU Zhiyuan ZHANG Zhongyuan wang Jiayi MA Xin tian Electronic Information School Wuhan University Computer Science School Wuhan University Wuhan Institute of Quantum Technology

Shape from polarization (SfP) method can use the polarization information in reflected light to estimate the surface normal of the target,which can further reconstruct the shape of the *** a simple image capture process,it can use low-cost equipment to meet a high precision imaging requirement,which can be used in remote scenes and other applications.

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen hai-Di Fan Wan wang Bin wang Ju-Yun Ma Peng-Peng Li hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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蠕变本构模型在时效成形仿真中的应用研究

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系统仿真学报 2009年第20期21卷 6647-6649页

作者：甘忠张海燕王田修西北工业大学现代设计与集成制造技术教育部重点实验室西安710072

为了在时效成形有限元模拟仿真的过程中得到更为精确的数值解,采用以经典塑性理论(CPT)为基础的蠕变本构方程,在蠕变试验的基础上,拟合了蠕变本构模型的参数B、m、n的值,并将该模型应用于T型试件的时效成形有限元模拟。通过与T型试件的... 详细信息

为了在时效成形有限元模拟仿真的过程中得到更为精确的数值解,采用以经典塑性理论(CPT)为基础的蠕变本构方程,在蠕变试验的基础上,拟合了蠕变本构模型的参数B、m、n的值,并将该模型应用于T型试件的时效成形有限元模拟。通过与T型试件的热压罐时效成形的数据相比较,在模具曲率半径R≥2000的情况下,数值模拟仿真的数据与试验数据的差异较大。因此根据试验数据对蠕变本构模型中的参数B、m、n的值进行了修正。应用修正后的本构方程进行模拟,最后得到的数值模拟的结果与时效成形的试验结果相比较,最大曲率半径偏差小于0.8mm,满足工程应用要求。

关键词：经典蠕变本构模型时效成形参数修正数值模拟

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基于信息融合原理的智能故障诊断模型

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计算机工程与应用 2004年第8期40卷 1-2,89页

作者：苏羽赵海田富俊王刚东北大学信息科学与工程学院沈阳110004

针对传统设备故障诊断方法中存在的局限性,文章在对设备智能故障原理和方法初步探索和研究的基础上,提出了基于信息融合原理的智能故障诊断方法。该方法利用多源异质传感器采集设备的各种特征信息,并采用模糊神经网络融合诊断中心作为... 详细信息

针对传统设备故障诊断方法中存在的局限性,文章在对设备智能故障原理和方法初步探索和研究的基础上,提出了基于信息融合原理的智能故障诊断方法。该方法利用多源异质传感器采集设备的各种特征信息,并采用模糊神经网络融合诊断中心作为诊断判决的执行机构,从而实现准确诊断设备故障诊断原因以及对设备运行工况进行态势评估的过程。并且通过对单传感器与多传感器信息融合诊断结果的对比表明多传感器信息融合诊断比单个传感器具有更高的准确性。

关键词：信息融合智能故障诊断模糊神经网络态势评估

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Mainchain conformation ordering self-assembly tailored room temperature phosphorescence emission

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Science China Chemistry 2025年第01期 329-336页

作者： Yuzhu Li Yumeng Gao Feng tian Yu wang Yuan Yao Shaoliang Lin Xiang Ma Binbin Xu Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences Key Laboratory for Advance Materials and Feringa Noble Prize Scientist Joint Research Centre Frontiers Science for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular Engineering East China University of Science & Technology

Developing organic room-temperature phosphorescence （RTP） materials with a wide range of tunable-emission is significant in expanding the applications of RTP ***,we rationally designed amphiphilic alternating copolymers poly(1,2-bis（4-alkoxyphenyl）ethane-1,2-dione-alt-（ethylene glycol）x)(P（Bz-alt-EGx）) that combined the advantage of alternating benzil and EGxskeleton,and tunable mainchain *** a mainchain conformation ordering assembly （COA） process,P（Bz-alt-EGx） self-assembled into well-defined platelets,and such assemblies emitted blue RTP at ca.425 nm due to the ordered folded-chain conformation and confined *** contrast,traditional self-assembly （TA） of P（Bz-alt-EGx） obtained less ordered aggregates,such as asymmetric worms,vesicles,and rod-like *** resultant less ordered aggregates exhibited yellow-green RTP at ca.550 *** wide-tuning RTP emission in solution （between blue and yellow-green,over125 nm） is realized using the P（Bz-alt-EGx） alternating copolymers under the treatment of different self-assembly *** study uncovers a new strategy to tailor the RTP emission through different self-assembly pathways and holds great promise for the fabrication of advanced optical materials.

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