检索结果-南通市图书馆

Dynamic changes and clinical value of lipocalin 2 in liver diseases caused by microbial infections

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第2期16卷 177-185页

作者： Feng Chen shan-shan wu Chao Chen Cheng Zhou State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesNational Medical Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina

Lipocalin 2(LCN2)plays a pivotal role in iron metabolism,particularly in the context of microbial infection resistance(e.g.,viruses,bacteria,parasites,etc.).LCN2 combats microbial infection by directly assisting the body in competing with microorganisms for iron,inducing immune cells to secrete various cytokines to enhance systemic immune responses,or recruiting neutrophils to infectious sites.The liver serves as the primary organ for LCN2 secretion during microbial infections.This review encapsulates recent advances in dynamic changes,clinical values,and the effects of LCN2 in infectious liver diseases caused by various microbial microorganisms.

关键词： Lipocalin 2 Microbial infection Immunity Liver diseases

Enhanced visible light absorption of Bi2WO6/SiO2 with abundant adsorbed oxygen for the degradation of organic pollutant

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第5期88卷 210-217页

作者： Yuanting wu Xiaoying Wang Wenlong Zhong shan Zhang School of Material Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China

Heterogeneous photocatalysts exhibit high catalytic efficiency in the degradation of pollutants,but their stability and repeatability is not very good and requires high structural matching.Simply by nanosizing the pure Bi 2 WO6(BWO)photocatalyst without constructing a heterojunction,there is a significant improvement in its performance,with an enhancement effect of about 2.3 times(99.43%).The high photocatalytic degradation efficiency of the material can be attributed to the enhanced light absorption effect brought by the three-dimensional inverse-opal structure SiO 2(IS)and the abundant surface adsorbed oxygen generated after the formation of Si–O–W bonds.In addition,the introduction of IS greatly increases the surface area of nanostructured BWO,which accelerates the charge transfer process,while the adsorbed oxygen promotes the participation of·O2−in the photocatalytic reaction,thereby accelerating the consumption of photo-generated electrons and ultimately improving the separation of charge carriers.Furthermore,the matched photonic bandgap further improves the absorption and utilization of light of the material.In this work,we constructs Si–O–W bonds to obtain inverse-opal SiO2/Bi2 WO6 with uniformly growth of pure phase nano BWO,which provides a feasible strategy for the preparation of high-performance pure-phase photocatalysts.

关键词： Bi2WO6 SiO2 inverse-opal structure Photocatalysis Adsorbed oxygen

Location of Asymmetric Ground Fault Using Virtual Injected Current Ratio and Two-stage Recovery Strategy in Distribution Networks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第1期10卷 151-161页

作者： haiting shan Luliang Zhang Q.H.wu Mengshi Li School of Electric Power Engineering South China University of Technology(SCUT)Guangzhou 510641China

Sparse measurements challenge fault location in distribution networks.This paper proposes a method for asymmetric ground fault location in distribution networks with limited measurements.A virtual injected current vector is formulated to estimate the fault line,which can be reconstructed from voltage sags measured at a few buses using compressive sensing(CS).The relationship between the virtual injected current ratio(VICR)and fault position is deduced from circuit analysis to pinpoint the fault.Furthermore,a two-stage recovery strategy is proposed for improving reconstruction accuracy of the current vector,where two different sensing matrixes are utilized to improve the incoherence.The proposed method is validated in IEEE 34 node test feeder.Simulation results show asymmetric ground fault type,resistance,fault position and access of distributed generators(DGs)do not significantly influence performance of our method.In addition,it works effectively under various scenarios of noisy measurement and line parameter error.Validations on 134 node test feeders prove the proposed method is also suitable for systems with more complex structure.

关键词： Distribution networks fault location reconstruction accuracy two-stage recovery virtual injected current ratio

Decentralized Primary Frequency Regulation for Hybrid Multi-terminal Direct Current Power Systems Considering Multi-source Enhancement

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 958-970页

作者： Jialiang wu Zhen Wang Ruixu Liu Yu shan Chenxuan Wang the College of Electrical Engineering Zhejiang University IEEE the Economic Research Institute of State Grid Zhejiang Electric Power Co. Ltd.

Hybrid multi-terminal direct current(MTDC) transmission technology has been a research focus, and primary frequency regulation(FR) improvement in the receiving-end system is one of the problems to be solved. This paper presents a decentralized primary FR scheme for hybrid MTDC power systems considering multi-source enhancement to help suppress frequency disturbance in the receiving-end systems. All the converters only need local frequency or DC voltage signal input to respond to system disturbance without communication or a control center, i. e., a decentralized control scheme. The proposed scheme can activate appropriate power sources to assist in FR in various system disturbance severities with fine-designed thresholds, ensuring sufficient utilization of each power source. To better balance FR performance and FR resource participation, an evaluation index is proposed and the parameter optimization problem is further conducted. Finally, the validity of the proposed scheme is verified by simulations in MATLAB/Simulink.

关键词： Frequency control HVDC transmission Voltage control Hybrid power systems Frequency conversion Voltage measurement Power system stability

Improvement of the nutritional support management system for patients in intensive care units

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第1期14卷 44-52页

作者： Yuan-Yuan Zhang Chun-Yi Wang Dong-Xian Guo hai-Nu Gao Xian-shan Jin Yan-Li wu Lu-Han Chen Zhi-Xian Feng Department of Critical Care Medicine Shulan(Hangzhou)HospitalZhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Department of Information Shulan(Hangzhou)HospitalZhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Department of Pharmacy Shulan(Hangzhou)HospitalZhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Department of Nutrition Shulan(Hangzhou)HospitalZhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina Administrative Office Shulan(Hangzhou)HospitalZhejiang Shuren University Shulan International Medical CollegeHangzhou 310022Zhejiang ProvinceChina

BACKGROUND Nutritional support for patients hospitalized in the intensive care unit(ICU)is an important part of clinical treatment and care,but there are significant implementation difficulties.AIM To introduce a modified nutritional support management system for ICU patients based on closed-loop information management and psychological counseling.METHODS The division of functions,personnel training,system construction,development of an intelligent decision-making software system,quality control,and improvement of the whole process were carried out to systematically manage nutritional support for ICU patients.RESULTS Following the implementation of the whole process management system,the scores of ICU medical staff’s knowledge,attitudes/beliefs,and practices regarding nutritional support were comprehensively enhanced.The proportion of hospital bed-days of total enteral nutrition(EN)in ICU patients increased from 5.58%to 11.46%,and the proportion of EN plus parenteral nutrition increased from 42.71%to 47.07%.The rate of EN initiation within 48 h of ICU admission increased from 37.50%to 48.28%,and the EN compliance rate within 72 h elevated from 20.59%to 31.72%.After the implementation of the project,the Self-rating Anxiety Scale score decreased from 61.07±9.91 points to 52.03±9.02 points,the Self-rating Depression Scale score reduced from 62.47±10.50 points to 56.34±9.83 points,and the ICU stay decreased from 5.76±2.77 d to 5.10±2.12 d.CONCLUSION The nutritional support management system based on closed-loop information management and psychological counseling achieved remarkable results in clinical applications in ICU patients.

关键词： Closed-loop information Psychological counseling Intensive care unit patients Nutritional support Management system

Recent research progress in the mechanism and suppression of fusion welding-induced liquation cracking of nickel based superalloys

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1072-1088页

作者： Zongli Yi Jiguo shan Yue Zhao Zhenlin Zhang Aiping wu Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China College of Engineering China Agricultural UniversityBeijing 100091China State Key Laboratory of Clean and Efficient Turbomachinery Power Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084China School of Material Science and Engineering Southwest Jiaotong UniversityChengdu 610031China

Nickel-based superalloys are extensively used in the crucial hot-section components of industrial gas turbines,aeronautics,and astronautics because of their excellent mechanical properties and corrosion resistance at high temperatures.Fusion welding serves as an effective means for joining and repairing these alloys;however,fusion welding-induced liquation cracking has been a challenging issue.This paper comprehensively reviewed recent liquation cracking,discussing the formation mechanisms,cracking criteria,and remedies.In recent investigations,regulating material composition,changing the preweld heat treatment of the base metal,optimizing the welding process parameters,and applying auxiliary control methods are effective strategies for mitigating cracks.To promote the application of nickel-based superalloys,further research on the combination impact of multiple elements on cracking prevention and specific quantitative criteria for liquation cracking is necessary.

关键词： nickel-based superalloy fusion welding liquation cracking cracking mechanism cracking suppression

Influence of blood glucose fluctuations on chemotherapy efficacy and safety in type 2 diabetes mellitus patients complicated with lung carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第4期15卷 645-653页

作者： Tian-Zheng Fang Xian-Qiao wu Ting-Qi Zhao shan-shan Wang Guo-Mei-Zhi Fu Qing-Long wu Cheng-Wei Zhou Department of Thoracic Surgery The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina Department of Endocrine The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina

BACKGROUND Patients with type 2 diabetes mellitus(T2DM)have large fluctuations in blood glucose(BG),abnormal metabolic function and low immunity to varying degrees,which increases the risk of malignant tumor diseases and affects the efficacy of tumor chemotherapy.Controlling hyperglycemia may have important therapeutic implications for cancer patients.AIM To clarify the influence of BG fluctuations on chemotherapy efficacy and safety in T2DM patients complicated with lung carcinoma(LC).METHODS The clinical data of 60 T2DM+LC patients who presented to the First Affiliated Hospital of Ningbo University between January 2019 and January 2021 were retrospectively analyzed.All patients underwent chemotherapy and were grouped as a control group(CG;normal BG fluctuation with a mean fluctuation<3.9 mmol/L)and an observation group(OG;high BG fluctuation with a mean fluctuation≥3.9 mmol/L)based on their BG fluctuations,with 30 cases each.BGrelated indices,tumor markers,serum inflammatory cytokines and adverse reactions were comparatively analyzed.Pearson correlation analysis was performed to analyze the correlation between BG fluctuations and tumor markers.RESULTS The fasting blood glucose and 2-hour postprandial blood glucose levels in the OG were notably elevated compared with those in the CG,together with markedly higher mean amplitude of glycemic excursions(MAGE),mean of daily differences,largest amplitude of glycemic excursions and standard deviation of blood glucose(P<0.05).In addition,the OG exhibited evidently higher levels of carbohydrate antigen 19-9,carbohydrate antigen 125,carcinoembryonic antigen,neuron-specific enolase,cytokeratin 19,tumor necrosis factor-α,interleukin-6,and highsensitivity C-reactive protein than the CG(P<0.05).Pearson analysis revealed a positive association of MAGE with serum tumor markers.The incidence of adverse reactions was significantly higher in the OG than in the CG(P<0.05).CONCLUSION The greater the BG fluctuation in LC patients after chemotherapy,the more unfavorable the therapeuti

关键词： Blood glucose fluctuation Type 2 diabetes mellitus Lung carcinoma Tumor markers

Engineering high-performance dielectric chiral shells with enhanced chiral fields for sensitive chiral biosensor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第3期43卷 1197-1206页

作者： Yi-Fan Wang shan-shan Huang Zhen-Dong Dai Shi-Lin Xian Xuan-Nan wu Fu-Hua Gao Yi-Dong Hou College of Physics Sichuan UniversityChengdu610065China Graduate School of Sichuan University Sichuan UniversityChengdu610065China

Chiral metamaterials have been a topic of significant research interest in recent years due to their potential for various applications in nanophotonic devices and chiral biosensors.However,the intrinsic Ohmic loss in surface plasmonic resonance has limited their practical use,resulting in large light dissipation and weak chiroptical resonance.Here,we report on the development of high-performance dielectric chiral shells(DCS)through a two-step Si deposition process on a self-assembled microsphere monolayer.The form DCS sample completely oyercomes the cancelation effect originated from the disorder property of the micro-sphere monolayer in macroscale,and at a wavelength of approximately 710 nm,the measured optimal chiral signal(g-factor)and transmittance can reach up to 0.7 and 0.3,respectively.The strong chiroptical effect comes from the asymmetric circular displacement currents(i.e.,magnetic modes)enabled by the specific shell geometry.The chiral shell geometry,electromagnetic properties,sensor sensitivity of chiral molecules and figure of merit are systematically investigated.The DCSs demonstrate highly sensitive detection of chiral biomolecules owing to their easily accessible geometry and enhanced uniform chiral field.

关键词： Dielectric chiral shells(DCS) Si deposition Magnetic resonance Highly sensitive sensor Chiral field

Photocatalytic vinyl radical-mediated multicomponent 1,4-/1,8-carboimination across alkynes and olefins/(hetero)arenes

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第2期67卷 558-567页

作者： shan-shan Li Yu-Shi Jiang Xue-Ling Luo Xuming Ran Yuqiang Li Dong wu Cheng-Xue Pan Peng-Ju Xia School of Chemistry and Pharmaceutical Sciences Guangxi Normal UniversityGuilin541004China shanghai Artificial Intelligence Laboratory Shanghai200433China The Institute for Advanced Studies Wuhan UniversityWuhan430064China

We developed a highly selective and efficient multicomponent transformation by utilizing alkynes and olefins/(hetero)arenes through photoinduced energy-transfer catalysis.The reaction involves the formation of three distinct chemical bonds,namely C(sp~3)–C(sp~2),C(sp~2)–C(sp~3),and C(sp~3)–N,in a single coordinated manner.The strategy used a vinyl radical-mediated radical relay approach under mild conditions,exhibiting a broad substrate scope(>70 examples),excellent functional-group tolerance,and remarkable regio-and anti-stereoselectivity.Through the utilization of a combination of experimental techniques and density functional theory(DFT),we delved deeper into the mechanistic intricacies of this distinctive system.Results revealed that the selective radical addition to electron-deficient alkynes,rather than olefins,was governed by the inherent reactivity of alkyl radicals.This discovery presented a highly effective approach for the synthesis of stereodefined multisubstituted alkenes.

关键词： alkyne-olefin coupling DFT studies regio-and anti-stereoselectivity multisubstituted alkenes