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A survey on dynamic graph processing on GPUs: concepts, terminologies and systems

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Frontiers of Computer Science 2024年第4期18卷 1-23页

作者： Hongru GAO Xiaofei liAO Zhiyuan SHAO Kexin li Jiajie CHEN hai JIN National Engineering Research Center for Big Data Technology and System/Services Computing Technology and System Lab/Cluster and Grid Computing Lab School of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China Zhejiang Lab Hangzhou 311121China

Graphs that are used to model real-world entities with vertices and relationships among entities with edges,have proven to be a powerful tool for describing real-world problems in *** most real-world scenarios,entities and their relationships are subject to constant *** that record such changes are called dynamic *** recent years,the widespread application scenarios of dynamic graphs have stimulated extensive research on dynamic graph processing systems that continuously ingest graph updates and produce up-to-date graph analytics *** the scale of dynamic graphs becomes larger,higher performance requiremen.s are demanded to dynamic graph processing *** the massive parallel processing power and high memory bandwidth,GPUs become mainstream vehicles to accelerate dynamic graph processing ***-based dynamic graph processing systems mainly address two challenges:maintaining the graph data when updates occur(i.e.,graph updating)and producing analytics results in time(i.e.,graph computing).In this paper,we survey GPU-based dynamic graph processing systems and review their methods on addressing both graph updating and graph *** comprehensively discuss existing dynamic graph processing systems on GPUs,we first introduce the terminologies of dynamic graph processing and then develop a taxonomy to describe the methods employed for graph updating and graph *** addition,we discuss the challenges and future research directions of dynamic graph processing on GPUs.

关键词： dynamic graphs graph processing graph algorithms GPUs

Experimen.al Study on Engineering Behavior of Solidified Soil for Scour Repair and Protection

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China Ocean Engineering 2024年第4期38卷 625-635页

作者： WU Xiao-ni li Ru-yu SHU Jian TANG Chao CHEN Jin-jian WANG Hui-li JIANG hai-li WANG Xiao State Key Laboratory of Ocean Engineering Department of Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Shanghai Road and Bridge Group Co. Ltd.Shanghai 200433China Shanghai Engineering Research Center of Urban Infrastructure Renewal Shanghai 200032China Jiangsu Kunze Technology Co. Ltd.Nanjing 210000China

A new scour countermeasure using solidified slurry for offshore foundation has been proposed *** solidified slurry is pumped to seabed area around foundation for scour protection or pumped into the developed scour holes for scour repair as the fluidized material solidifies *** the pumping operation and solidification,the engineering behaviors of solidified slurry require to be considered synthetically for the reliable application in scour repair and protection of ocean engineering such as the pumpability related flow value,flow diffusion behavior related rheological property,anti-scour performance related retention rate in solidification and bearing capacity related strength property after *** this study,a series of laboratory tests are conducted to investigate the effects of mix proportion(initial water content and binder content)on the flow value,rheological properties,density,retention rate of solidified slurry and unconfined compressive strength(UCS).The results reveal that the flow value increases with the water content and decreases with the binder *** the solidified slurry exhibits Bingham plastic behavior when the shear rate is larger than 5 s^(-1).The Bingham model has been employed to fit the rheology test results,and empirical formulas for obtaining the density,yield stress and viscosity are established,providing scientific support for the numerical assessmen. of flow and diffusion of solidified *** rate of solidified slurry decreases with the water flow velocity and flow value,which means the pumpability of solidified slurry is contrary to anti-scour *** unconfined compressive strength after solidification reduces as the water content increases and binder content decreases.A design and application procedure of solidified soil for scour repair and protection is also proposed for engineering reference.

关键词： scour repair and protection solidified soil pumpability strength flow properties anti-scour performance

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Human influence on the duration of extreme temperature events in Asia's hotspot regions

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Advances in Climate Change Research 2024年第2期15卷 312-326页

作者： Zi-men. WANG Hong-Yun MA Wei li hai-Shan CHEN Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)/Key Laboratory of Meteorological Disaster Ministry of Education(KLME)Nanjing University of Information Science and TechnologyNanjing 210044China

Observations and models indicate that human activities exert a considerable impact on the frequency and intensity of extreme temperature events,which are associated with global ***,changes in the duration of extreme temperature events and their association with human influence have not been considered in most ***,the possible relationship between the observed changes in the warm and cold spell duration(WSDI and CSDI)in hotspot regions during 1960-2014 and human influence was investigated based on the NCEP/NCAR reanalysis version 1 and Coupled Model Inter-comparison Project Phase 6(CMIP6)*** projection based on these attribution results was also *** optimal fingerprinting technique was used to compare observed changes in WSDI and CSDI to simulated changes averaged across eight CMIP6 *** show that anthropogenic(ANT)forcing contributed to the observed increase in WSDI in the three hotspot regions(West Asia,South Asia and Southeast Asia),with the majority of the changes being attributed to greenhouse gas ***,a generally weak ANT signal can be observed in the decreasing trend of CSDI and can be detected in South and Southeast *** influence of aerosol forcing remains undetected in either WSDI or CSDI,which differs from the results for frequency and intensity of extreme *** attribution results revealed that the constrained projection of WSDI is lower than the raw projection for 2015-2100 in West Asia and Southeast ***,no differences in future CSDI changes are found in Southeast Asia between the constrained and raw projections.

关键词： Extreme temperature events Duration Detection attribution Constraint projection Hotspot regions

Improving the Forecasts of Coastal Wind Speeds in Tianjin,China Based on the WRF Model with Machine Learning Algorithms

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Journal of Meteorological Research 2024年第3期38卷 570-585页

作者： Weihang ZHANG men. TIAN Shangfei hai Fei WANG Xiadong AN Wanju li Xiaodong li lifang SHENG College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao266100China Tianjin Key Laboratory for Oceanic Meteorology Tianjin Institute of Meteorological ScienceTianjin300074China CMA Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing100081China Qingdao Meteorological Bureau Qingdao266003China

Characterized by sudden changes in strength,complex influencing factors,and significant impacts,the wind speed in the circum-Bohai Sea area is relatively challenging to *** the western side of Bohai Bay,as the economic center of the circum-Bohai Sea,Tianjin exhibits a high demand for accurate wind *** this study,three machine learning algorithms were employed and compared as post-processing methods to correct wind speed forecasts by the Weather Research and Forecast(WRF)model for *** results showed that the random forest(RF)achieved better performance in improving the forecasts because it substantially reduced the model bias at a lower computing cost,while the support vector machine(SVM)performed slightly worse(especially for stronger winds),but it required an approximately 15 times longer computing *** back propagation(BP)neural network produced an average forecast significantly closer to the observed forecast but insufficiently reduced the *** regard to wind speed frequency forecasting,the RF method commen.ably corrected the forecasts of the frequency of moderate(force 3)wind speeds,while the BP method showed a desirable capability for correcting the forecasts of stronger(force>6)*** addition,the 10-m u and v components of wind(u_(10)and v_(10)),2-m relative humidity(RH_(2))and temperature(T_(2)),925-hPa u(u925),sea level pressure(SLP),and 500-hPa temperature(T_(500))were identified as the main factors leading to bias in wind speed forecasting by the WRF model in Tianjin,indicating the importance of local dynamical/thermodynamic processes in regulating the wind *** study demonstrates that the combination of numerical models and machine learning techniques has important implications for refined local wind forecasting.

关键词： machine learning Weather Research and Forecast(WRF)model wind speed forecasting coastal region

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Supermassive black holes triggered by QCD axion bubbles

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Communications in Theoretical Physics 2024年第5期76卷 134-139页

作者： hai-Jun li Ying-Quan Peng Wei Chao Yu-Feng Zhou Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Center for Advanced Quantum Studies Department of PhysicsBeijing Normal UniversityBeijing 100875China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Fundamen.al Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUCASHangzhou 310024China International Centre for Theoretical Physics Asia-Pacific Beijing/HangzhouChina

Supermassive black holes(SMBHs)are ubiquitous in the center of galaxies,although the origin of their massive seeds is still *** this paper,we investigate the formation of SMBHs from the quantum chromodynamics(QCD)axion *** this case,primordial black holes(PBHs)are considered as the seeds of SMBHs,which are generated from the QCD axion bubbles due to an explicit Peccei–Quinn(PQ)symmetry breaking after *** QCD axion bubbles are formed when the QCD axion starts to oscillate during the QCD phase *** consider a general case in which the axion bubbles are formed with the bubble effective angle θ_(eff)∈(0,π],leading to the minimum PBH mass∼■(10^(4)−10^(7))M⊙for the axion decay constant f_(a)∼■(10^(16))*** PBHs at this mass region may account for the seeds of SMBHs.

关键词： supermassive black holes primordial black holes quantum chromodynamics axion

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Protein succinylation,hepatic metabolism,and liver diseases

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World Journal of Hepatology 2024年第3期16卷 344-352页

作者： Shuang liu Rui li Ya-Wen Sun hai lin hai-Fang li College of Animal Science and Veterinary Medicine Shandong Agricultural UniversityTai’an 271018Shandong ProvinceChina College of life Sciences Shandong Agricultural UniversityTai’an 271018Shandong ProvinceChina

Succinylation is a highly conserved post-translational modication that is processed via enzymatic and non-enzymatic *** exhibits strong effects on protein stability,enzyme activity,and transcriptional *** succinylation is extensively present in the liver,and increasing evidence has demonstrated that succinylation is closely related to hepatic *** instance,histone acetyltransferase 1 promotes liver glycolysis,and the sirtuin 5-induced desuccinylation is involved in the regulation of the hepatic urea cycle and lipid ***,the effects of succinylation on hepatic glucose,amino acid,and lipid metabolism under the action of various enzymes will be discussed in this *** addition,how succinylases regulate the progression of different liver diseases will be reviewed,including the desuccinylation activity of sirtuin 7,which is closely associated with fatty liver disease and hepatitis,and the actions of lysine acetyltransferase 2A and histone acetyltransferase 1 that act as succinyltransferases to regulate the succinylation of target genes that influence the developmen. of hepatocellular *** view of the diversity and significance of protein succinylation,targeting the succinylation pathway may serve as an attractive direction for the treatmen. of liver diseases.

关键词： Protein succinylation Hepatic metabolism Fatty liver Hepatitis Hepatocellular carcinoma

Propylene epoxidation coupled with furfural oxidation over Pt(Ⅱ?) TPP porphyrin with molecular oxygen

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Green Chemical Engineering 2024年第4期5卷 519-525页

作者： Hong-Qi li hai-Yang Yu Yang li Xiao-Qi He Xian-Tai Zhou Huizhou Research Institute Sun Yat-sen University School of Chemical Engineering and Technology Sun Yat-sen University

The developmen. of green route for preparing propylene oxide (PO) with molecular oxygen is of significance both in academic and industrial. In this work, propylene epoxidation coupled with furfural oxidation catalyzed by platinum meso-tetraphenylporphyrin (Pt (II)TPP) has been developed. Propylene conversion and PO selectivity reached up to 56%and 83%, respectively. Meanwhile, furfural was almost completely converted to furoic *** on operando characterizations and electron paramagnetic resonance (EPR) tests, a mechanism involved high-valent Pt species was proposed. This work is expected to provide a potential application prospects for producing PO and furoic acid simultaneously in chemical industry.

关键词： Propylene Epoxidation Molecular oxygen Furfural Platinum porphyrins

Anti-inflammatory and DNA Repair Effects of Astragaloside IV on PC12 Cells Damaged by lipopolysaccharide

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Current Medical Science 2024年第4期44卷 854-863页

作者： hai-long li li-hua SHAO Xi CHEN men. WANG Qi-jie QIN Ya-li YANG Guang-run ZHANG Yang hai Yi-hong TIAN Departmen. of Geriatrics The Affiliated Hospital of Gansu University of Chinese MedicineLanzhou730000China Key Laboratory for Mining Innovation and Transformation of Traditional Chinese Medicine in Gansu Province and the New Product Creation Engineering Laboratory of Traditional Chinese Medicine in Gansu ProvinceLanzhou730000China Departmen. of Neurology the First People’s Hospital of LanzhouLanzhouGansu730000China School of Public Health Gansu University of Chinese MedicineLanzhou730000China People’s Hospital of Gansu Province Lanzhou730000China Scientific Research and Experimen.al Center Gansu University of Chinese MedicineLanzhou730000China

Objective This study aimed to establish a neural cell injury model in vitro by stimulating PC12 cells with lipopolysaccharide(LPS)and to examine the effects of astragaloside IV on key targets using high-throughput sequence technology and bioinformatics *** PC12 cells in the logarithmic growth phase were treated with LPS at final concentrations of 0.25,0.5,0.75,1,and 1.25 mg/mL for 24 *** morphology was evaluated,and cell survival rates were calculated.A neurocyte inflammatory model was established with LPS treatmen.,which reached a 50%cell survival ***12 cells were treated with 0.01,0.1,1,10,or 100µmol/L astragaloside IV for 24 *** concentration of astragaloside IV that did not affect the cell survival rate was selected as the treatmen. group for subsequent *** activity was detected by colorimetry;the expression levels of ERCC2,XRCC4,XRCC2,TNF-α,IL-1β,TLR4,NOS and COX-2 mRNA and protein were detected by RT-qPCR and Western *** differentially expressed genes(DEGs)between the groups were screened using a second-generation sequence(fold change>2,Pmen. analysis,RT-qPCR and Western blotting were used to detect the mRNA and protein expression of DEGs related to the IL-17 pathway in different groups of PC12 *** The viability of PC12 cells was not altered by treatmen. with 0.01,0.1,or 1µmol/L astragaloside IV for 24 h(P>0.05).However,after treatmen. with 0.5,0.75,1,or 1.25 mg/mL LPS for 24 h,the viability steadily decreased(P<0.01).The mRNA and protein expression levels of ERCC2,XRCC4,XRCC2,TNF-α,IL-1β,TLR4,NOS,and COX-2 were significantly increased after PC12 cells were treated with 1 mg/mL LPS for 24 h(P<0.01);however,these changes were reversed when PC12 cells were pretreated with 0.01,0.1,or 1µmol/L astragaloside IV in PC12 cells and then treated with 1 mg/mL LPS for 24 h(P<0.05).Second-generation sequencing revealed that 1026 genes were upregulated,while 1287 genes were downregulat

关键词： PC12 cells astragaloside IV inflammation DNA damage

Prognostic value of PEA3 subfamily gene expression in cholangiocarcinoma

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 4014-4027页

作者： li Wang Zhe Zhang hai-Zhang Ma Departmen. of Emergency The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Departmen. of Emergency Medicine The First People’s Hospital of Linping District HangzhouHangzhou 311100Zhejiang ProvinceChina Departmen. of General Surgery Qilu Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina

BACKGROUND Cholangiocarcinoma(CCA)is a lethal malignancy with limited treatmen. options and poor *** PEA3 subfamily of E26 transformation specific genes:ETV1,ETV4,and ETV5 are known to play significant roles in various cancers by influencing cell proliferation,invasion,and *** To analyze PEA3 subfamily gene expression levels in CCA and their correlation with clinical parameters to determine their prognostic value for *** The expression levels of PEA3 subfamily genes in pan-cancer and CCA data in the cancer genome atlas and genotype-tissue expression project databases were analyzed with R language *** curve and receiver operating characteristic analyses were performed using the SurvMiner,Survival,and Procr language *** gene expression profiling interactive analysis 2.0 database was used to analyze the expression levels of PEA3 subfamily genes in different subtypes and stages of *** Gestalt was used to perform the gene ontology/Kyoto encyclopedia of genes and genomes(GO/KEGG)analysis,and STRING database analysis was used to determine the genes and proteins related to PEA3 subfamily *** ETV1,ETV4,and ETV5 expression levels were significantly increased in *** were significant differences in ETV1,ETV4,and ETV5 expression levels among the different subtypes of CCA,and predictive analysis revealed that only high ETV1 and ETV4 expression levels were significantly associated with shorter overall survival in patients with ***/KEGG analysis revealed that PEA3 subfamily genes were closely related to transcriptional misregulation in *** vitro and in vivo experimen.s revealed that PEA3 silencing inhibited the invasion and metastasis of CCA *** The expression level of ETV4 may be a predictive biomarker of survival in patients with CCA.

关键词： PEA3 subfamily Cholangiocarcinoma The cancer genome atlas ETV4 The prognosis Prognostic biomarker