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Acute pancreatitis-induced thrombotic thrombocytopenic purpura:A case report

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World Journal of Clinical Cases 2022年第12期10卷 3808-3813页

作者： Chun-Hua Wang hai-feng jin Wen-Ge Liu Ying Guo Zhen Liu Department of Gastroenterology The 980^(th) Hospital of the People's Liberation Army Joint Service(Bethune International Peace Hospital)Shijiazhuang 050082Hebei ProvinceChina

BACKGROUND Thrombotic thrombocytopenic purpura(TTP)is a life-threatening but treatable *** pancreatitis is a well-described consequence of TTP,but TTP as a consequence of acute pancreatitis is *** SUMMARY A 32-year-old male developed acute pancreatitis due to a fatty diet and suffered splenectomy 3 years ago due to *** day 4 of his onset of pain the blood examination showed the platelet extremely reduced,bilirubin elevated and creatinine *** clinical suspicion of TTP was made and prompt initiation of plasma exchange was given followed intravenous drip *** 7 sessions of plasm exchange and the laboratory parameters were back to normal and the patient was discharged from the hospital on the 13th day of *** Patients develop acute pancreatitis with no apparent causes for hemolytic anemia and thrombocytopenia,the possibility of TTP should be *** for TTP including plasm exchange should be evaluated as soon as a diagnosis is made.

关键词： Thrombotic thrombocytopenic purpura Acute pancreatitis Case report Plasm exchange Glucocorticoid

Transformation of Structure and Properties of Vesicles Induced by Transition Metal Ions

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Chinese Chemical Letters 2005年第12期16卷 1667-1670页

作者： Hong Tao GUO Fei XU Xiao hai ZHOU jin feng DONG Gao Yong ZHANG Xin Lin HONG College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072

This paper proved that octodecyl propylenediamine could form vesicles in pure water and aqueous solution of CuCl2 or Cu（NO3）2. The structure and morphology of vesicles were different when the copper （Ⅱ） salt was added to the solution. The results showed that both the counterions and the ligands had strong influence on the configuration of coordinated structures and packing model in bilayer membrane of vesicles.

关键词： Octodecyl propylenediamine copper (Ⅱ) ions vesicle bilayer membrane counterions coordinated structure

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Expression of p-STAT3 and vascular endothelial growth factor in MNNG-induced precancerous lesions and gastric tumors in rats

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World Journal of Gastrointestinal Oncology 2016年第3期8卷 305-313页

作者： Xiao-Yan Wang Lou-Lei Wang Xuan Zheng Li-Na Meng Bin Lyu hai-feng jin the First Affiliated Hospital of Zhejiang University the First Affiliated Hospital of Zhejiang Chinese Medicine University

AIM: To investigate the dynamic expression of p-signal transducer and activator of transcription 3 (STAT3) and vascular endothelial growth factor (VEGF) in the formation of gastric tumors induced by drinking water containing N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) in Wistar rats. METHODS: One hundred and twenty Wistar rats were randomly divided into two groups (60 in each group): Control group and Model group. The rats in each group were then randomly divided into three groups (20 in each group): C/M15, C/M25 and C/M40 (15, 25 and 40 represent the number of feeding weeks from termination). Rats in the control group received normal drinking water and rats in the model group received drinking water containing 100 μg/mL MNNG. Stomach tissues were collected at the end of the 15th, 25th and 40th week, respectively, for microscopic measurement using hematoxylin and eosin staining. The expression of p-STAT3 and VEGF in different pathological types of gastric tissue, including normal, inflammation, atrophy, hyperplasia and gastric stromal tumor, was observed by immunohistochemistry and Western blot, and the corelation between p-STAT3 and VEGF was analyzed. RESULTS: (1) The expression of p-STAT3 in tissue with gastritis, atrophy, dysplasia and gastric stromal tumor were significantly increased in the model group compared with the control group (2.5 ± 1.0, 2.75 ± 0.36, 6.2 ± 0.45, 5.67 ± 0.55 vs 0.75 ± 0.36, P = 0.026, 0.035, 0.001, 0.002, respectively); the expression of p-STAT3 in tissue with dysplasia was higher than that in samples with gastritis or atrophy (6.2 ± 0.45 vs 2.5 ± 1.0, P = 0.006; 6.2 ± 0.45 vs 2.75 ± 0.36, P = 0.005, respectively); however, the expression of p-STAT3 in gastritis and atrophy was not significantly different (P > 0.05); (2) the expression of VEGF in tissue with gastritis, atrophy, dysplasia and gastric stromal tumor was significantly inc

关键词： Wistar rat Precancerous gastric lesions Gastric tumor Vascular endothelial growth factor p-signal transducer and activator of transcription 3 N-methyl-N&rsquo -nitro-N-nitrosoguanidine

Case report of primary splenic angiosarcoma with hepatic metastases

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World Journal of Gastroenterology 2015年第39期21卷 11199-11204页

作者： Fang Chen hai-feng jin Yi-Hong Fan Li-Jun Cai Zhuo-Yi Zhang Bin Lv Department of Gastroenterology The First Affiliated Hospital of Zhejiang Chinese Medical University Department of Emergency The First Affiliated Hospital of Zhejiang Chinese Medical University

Primary splenic angiosarcoma(PSA) is the most unusual type of malignancy with early multifocal metastasis through hematogenous spread. PSA is generally believed to originate from splenic sinusoidal vascular endothelium with a high rate of metastasis and to have a poor prognosis. Its etiology and pathogenetic mechanisms have not yet been clearly described. Thus far, only approximately 200 cases have been reported. PSA has variable symptomatology with the potential to present with life-threatening complications. The diagnosis of PSA is challenging; and often late. PSA should be considered in the differential diagnosis of patients with splenomegaly and anemia of unknown etiology. Surgical treatment with splenectomy is considered the only curative intervention for potential long-term disease-free survival. Early diagnosis and treatment are very important. It is important that clinical doctors improve the understanding of PSA. Herein, we report one rare case of PSA with hepatic metastases, along with a review of the current literature.

关键词： Primary splenic angiosarcoma Hepatic metastases Ru

R-matrix calculation for photoionization

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原子与分子物理学报 2000年第2期17卷 365-368页

作者： JIANG Yu hai, SUN jin feng, WAN Ling de (Department of Physics, Henan Normal University, Xinxiang 453002) 河南师范大学河南新乡 453 0 0 2

We have employed the R matrix method to calculate differential cross sections for photoionization of helium leaving helium ion in an excited state for incident photon energy between the N=2 and N=3 thresholds (69～73 eV) of He + ion. Differential cross sections for photoionization in the N=2 level at emission angle 0° are provide. Our results are in good agreement with available experimental data and theoretical calculations.

关键词： R matrix Photoionization

Endoscopic surgery for giant esophageal leiomyoma:a case report;review of the literatures

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Endoscopic surgery for giant esophageal leiomyoma:a case rep...

Metal Ions Induced Vesicle Formation of Single-Chained Hydrocarbon Surfactants with Coordinated Headgroups

第三十一届全国中西医结合消化系统疾病学术会议

作者： hai-feng jin Shuo Zhang Xuan Huang hai-biao Bao Li-na Meng Bin Lyu Division of Gastroenterology The First Affiliated Hospital of Zhejiang Chinese Medical University Key Laboratory of Pathology and Physiology of Digestive Tract Disease in Zhejiang Province

Despite the rapid development of minimally invasive surgery,the treatment of esophageal lesions remains *** esophageal leiomyoma could be removed once diagnosed by surgery,but its operative method is not very acceptable for most patients because of risk and side effects of *** therapy has advantage in esophageal leiomyoma of small size;however,it is rarely reported for the adhibition of endoscopic therapy in giant esophageal *** report a case of giant esophageal leiomyoma and review published cases of giant leiomyomas in the past 10 years.A 42-year-old woman was admitted to the clinic for the complaints of 2-years history of dysphagia and *** tomography and endoscopic findings suggested esophageal lesion (the size was more than 8.0×5.0cm) in the muscular *** endoscopic submucosal dissection (ESD) was performed to relieve the patient’s *** speaking,the postoperative course was uneventful although with a little long time,the patient started oral fluid intake on the 9postoperative day,and was discharged on the 26 postoperative ***-up showed that endoscopic therapy was successful both in lesion dissection and improvement of ***,for the giant esophageal leiomyoma,endoscopic therapy is worth considering.

关键词： Giant esophageal leiomyomas endoscopic therapy

来源： cnki会议评论

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Wuhan University Journal of Natural Sciences 2005年第6期10卷 1035-1040页

作者： GUO Hong-tao XU Fei GAO Nan ZHOU Xiao-hai DONG jin-feng HONG Xin-lin ZHANG Gao-yong College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072 Hubei China

The surfactant of N-dodecyliminodipropionate disodium salt has been synthesized, and structure has been well characterized. The properties in aqueous solution have been studied by potentiometric titration, surface tension, transmission electron microscopy （TEM） and uhra-violet （UV） spectra. It was found that N-dodecyliminodipropionate disodium could exist in four species （e. g. cation, zwitterion, monoanion, dianion） in aqueous solution depending on pH,and relative distribution of these ionic species as a function of pH was obtained. The critical micelle concentration （CMC）, determined from the breakpoint of surface tension at different concentrations, is 4. 16 × 10^1 mol/L, and the surface tension at CMC is 30 mN/m. It was found that the self-aggregate structures in aqueous solution transformed from micelles to vesicles after the Cu （Ⅱ） added. The experimental results showed that coordination between the iminodipropionate group and Cu（Ⅱ） resulted to vesicles formation.

关键词： surfactant micelle vesicle metal ion iminodipropionate

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Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression

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World Journal of Psychiatry 2025年第1期15卷 32-36页

作者： Min Xu hai-Ying jin feng-Li Sun Wei-Dong jin Department of Psychiatry Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Psychiatry Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Department of Psychiatry Zhejiang Provincial Mental Health CenterHangzhou 311122Zhejiang ProvinceChina

Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent ***,many adolescent depression treatment guidelines still recommend the use of antidepressants,especially specific serotonin re-uptake *** studies have suggested that antidepressants have little therapeutic effect but many side effects,such as switching to mania,suicide,and non-suicidal self injury(NSSI),in the treatment of child and adolescent *** the process of developing guidelines,drug recommendations should not only focus on impro-ving symptoms,but they should also consider potential side *** review discusses the serious side effects of antidepressants,including switching to mania,suicide,and NSSI.

关键词： Child depression Adolescent depression Antidepressant Switch Suicide Non-suicidal self injury

Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 97-108页

作者： Pan Guo Hong-Bo jin Cong-feng Qiao Yue-Liang Wu The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences The School of Physical Sciences University of Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University National Astronomical Observatories Chinese Academy of Sciences Institute of Theoretical Physics Chinese Academy of Sciences

For space-based gravitational wave （GW） detection,the main noise source for massive black hole binaries （MBHBs） is attributed to approximately 10～7double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratio ?DL/DLat the 95%confidence level,is enhanced by factors of ～*** angular resolutions,denoted by??s,are enhanced by a factor of ～*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries