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The Generalized Regular Points and Narrow Spectrum Points of Bounded Linear Operators on Hilbert Spaces

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Acta mathematica Sinica,English Series 2010年第12期26卷 2349-2354页

作者： hai feng ma Henryk HUDZIK Yu Wen WANG Zhao feng ma School of mathematical Science Harbin Normal University Harbin 150025 P. R. China Faculty of mathematics and Computer Science Adam Mickiewicz University Umultowska 87 61-614 Poznad Poland Yuan-Yung Tseng Functional Analysis Research Center Harbin Normal University Harbin 150025 P. R. China Department of management and Information Zhejiang Institute of Communications Hangzhou 311112 P. R. China

In this paper, we introduce the concepts of generalized regular points and narrow spectrum points of bounded linear operators on Hilbert spaces. The concept of generalized regular points is an extension of the concept regular points, and so, the set of all spectrum points is reduced to the narrow spectrum. We present not only the same and different properties of spectrum and of narrow spectrum but also show the relationship between them. Finally, the well known problem about the invariant subspaces of bounded linear operators on separable Hilbert spaces is simplified to the problem of the operator with narrow spectrum only.

关键词： Locally fine point rank theorem narrow spectrum spectral radius invariant subspace

Continuous Homogeneous Selections of Set-Valued Metric Generalized Inverses of Linear Operators in Banach Spaces

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Acta mathematica Sinica,English Series 2012年第1期28卷 45-56页

作者： hai feng ma Henryk HUDZIK Wen WANG School of mathematical Science Harbin Normal UniversityHarbin 150025P.R.China Faculty of mathematics and Computer Science Adam Mickiewicz UniversityUmultowska 8761-614 PoznanPoland Yuan-Yung Tseng Functional Analysis Research Center Harbin Normal UniversityHarbin 150025P.R.China

In this paper, continuous homogeneous selections for the set-valued metric generalized inverses T^ of linear operators T in Banach spaces are investigated by means of the methods of geometry of Banach spaces. Necessary and sufficient conditions for bounded linear operators T to have continuous homogeneous selections for the set-valued metric generalized inverses T~ are given. The results are an answer to the problem posed by Nashed and Votruba.

关键词： Continuous homogeneous selection metric generalized inverse approximative compactness metric projection

Perturbations of Moore–Penrose Metric Generalized Inverses of Linear Operators in Banach Spaces

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Acta mathematica Sinica,English Series 2014年第7期30卷 1109-1124页

作者： hai feng ma Shuang SUN Yu Wen WANG Wen Jing ZHENG School of mathematical Science Harbin Normal University Department of mathematics Hulunbuir College

In this paper, the perturbations of the Moore-Penrose metric generalized inverses of linear operators in Banach spaces are described. The Moore Penrose metric generalized inverse is homo- geneous and nonlinear in general, and the proofs of our results are different from linear generalized inverses. By using the quasi-additivity of Moore-Penrose metric generalized inverse and the theorem of generalized orthogonal decomposition, we show some error estimates of perturbations for the single- valued Moore-Penrose metric generalized inverses of bounded linear operators. Furthermore, by means of the continuity of the metric projection operator and the quasi-additivity of Moore-Penrose metric generalized inverse, an expression for Moore-Penrose metric generalized inverse is given.

关键词： Banach space Moore-Penrose metric generalized inverse perturbation

A Review on Vibration Control of Multiple Cylinders Subjected to FlowInduced Vibrations

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China Ocean Engineering 2024年第2期38卷 183-197页

作者： XU Wan-hai ma Ye-xuan State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation Tianjin UniversityTianjin 300350China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China

The fatigue damage caused by flow-induced vibration(FIV)is one of the major concerns for multiple cylindrical structures in many engineering *** FIV suppression is of great importance for the security of many cylindrical *** active and passive control methods have been employed for the vibration suppression of an isolated cylinder undergoing vortex-induced vibrations(VIV).The FIV suppression methods are mainly extended to the multiple cylinders from the vibration control of the isolated *** to the mutual interference between the multiple cylinders,the FIV mechanism is more complex than the VIV mechanism,which makes a great challenge for the FIV *** efforts have been devoted to vibration suppression of multiple cylinder systems undergoing FIV over the past two *** control methods,such as helical strakes,splitter plates,control rods and flexible sheets,are not always effective,depending on many influence factors,such as the spacing ratio,the arrangement geometrical shape,the flow velocity and the parameters of the vibration control *** FIV response,hydrodynamic features and wake patterns of the multiple cylinders equipped with vibration control devices are reviewed and *** FIV suppression efficiency of the vibration control methods are analyzed and compared considering different influence *** research on the FIV suppression of multiple cylinders is suggested to provide insight for the development of FIV control methods and promote engineering applications of FIV control methods.

关键词： flow-induced vibration vibration control multiple cylinders tandem side-by-side staggered

Clinical manifestations and spermatogenesis outcomes in Chinese patients with congenital hypogonadotropic hypogonadism caused by inherited or de novo FGFR1 mutations

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Asian Journal of Andrology 2024年第4期26卷 426-432页

作者： Yu-Fan Yang hai-Lu ma Xi Wang Min Nie Jiang-feng mao Xue-Yan Wu Department of Endocrinology Peking Union Medical College HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100730China.

Fibroblast growth factor receptor 1(FGFR1)mutations are associated with congenital hypogonadotropic hypogonadism(CHH)through inheritance or spontaneous *** detected FGFR1 mutations in a Chinese cohort of 210 CHH patients at Peking Union Medical College Hospital(Beijing,China)using next-generation and Sanger *** assessed missense variant pathogenicity using six bioinformatics tools and compared clinical features and treatment outcomes between inherited and de novo mutation *** 19 patients with FGFR1 mutations,three were recurrent,and 16 were novel *** of the novel mutations were likely pathogenic according to the American College of Medical Genetics and Genomics(ACMG)guidelines,with the prevalent P366L *** majority of FGFR1 mutations was inherited(57.9%),with frameshift mutations exclusive to the de novo mutation *** inherited mutation group had a lower incidence of cryptorchidism,short stature,and skeletal *** the inherited mutation group,luteinizing hormone(LH)levels were 0.5 IU l−1,follicle-stimulating hormone(FSH)levels were 1.0 IU l−1,and testosterone levels were 1.3 nmol l−*** contrast,the de novo group had LH levels of 0.2 IU l−1,FSH levels of 0.5 IU l−1,and testosterone levels of 0.9 nmol l−1,indicating milder hypothalamus–pituitary–gonadal axis(HPGA)functional deficiency in the inherited *** inherited mutation group showed a tendency toward higher spermatogenesis *** conclusion,this study underscores the predominance of inherited FGFR1 mutations and their association with milder HPGA dysfunction compared to de novo mutations,contributing to our understanding of the genetic and clinical aspects of FGFR1 mutations.

关键词： congenital hypogonadotropic hypogonadism de novo FGFR1 inherited

CToMP: a cycle-task-oriented memory protection scheme for unmanned systems

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Science China(Information Sciences) 2024年第6期67卷 399-417页

作者： Chengyan ma Ning XI Di LU Yebo feng Jianfeng ma School of Cyber Engineering Xidian University School of Computer Science and Technology Xidian University Department of Computer and Information Science University of Oregon

Memory corruption attacks(MCAs) refer to malicious behaviors of system intruders that modify the contents of a memory location to disrupt the normal operation of computing systems, causing leakage of sensitive data or perturbations to ongoing processes. Unlike general-purpose systems, unmanned systems cannot deploy complete security protection schemes, due to their limitations in size, cost and *** in unmanned systems are particularly difficult to defend against. Furthermore, MCAs have diverse and unpredictable attack interfaces in unmanned systems, severely impacting digital and physical sectors. In this paper, we first generalize, model and taxonomize MCAs found in unmanned systems currently, laying the foundation for designing a portable and general defense approach. According to different attack mechanisms,we found that MCAs are mainly categorized into two types — return2libc and return2shellcode. To tackle return2libc attacks, we model the erratic operation of unmanned systems with cycles and then propose a cycle-task-oriented memory protection(CToMP) approach to protect control flows from tampering. To defend against return2shellcode attacks, we introduce a secure process stack with a randomized memory address by leveraging the memory pool to prevent Shellcode from being executed. Moreover, we discuss the mechanism by which CTo MP resists the return-oriented programming(ROP) attack, a novel variant of return2libc attacks. Finally, we implement CTo MP on CUAV V5+ with Ardupilot and Crazyflie. The evaluation and security analysis results demonstrate that the proposed approach CTo MP is resilient to various MCAs in unmanned systems with low footprints and system overhead.

关键词： unmanned system memory corruption attack memory protection system security randomized memory address

Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy

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Military Medical Research 2024年第1期11卷 98-114页

作者： Guang-Long ma Wei-feng Lin Faculty of Medicine Centre for Cancer ImmunologyUniversity of SouthamptonSouthampton SO166YDUK Department of Molecular Chemistry and materials Science Weizmann Institute of Science76100 RehovotIsrael Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China

Immune checkpoint blockade(ICB)therapy for cancer has achieved great success both in clinical results and on the *** the same time,success drives more attention from scientists to improve ***,only a small portion of patients are responsive to this therapy,and it comes with a unique spectrum of side effects termed immunerelated adverse events(irAEs).The use of nanotechnology could improve ICBs’delivery to the tumor,assist them in penetrating deeper into tumor tissues and alleviate their *** nanomedicine has been investigated and used for decades,and is well-recognized as the most successful nano-drug delivery *** successful combination of ICB with liposomal nanomedicine could help improve the efficacy of ICB *** this review,we highlighted recent studies using liposomal nanomedicine(including new emerging exosomes and their inspired nanovesicles)in associating ICB therapy.

关键词： Liposome Exosome Immune checkpoint blockade(ICB)

Influence of insulin resistance on long-term outcomes in patients with coronary artery disease after sirolimus-eluting stent implantation

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Chinese Medical Journal 2010年第6期123卷 651-657页

作者： ZHAO Liang-ping LU An-kang SHEN Wei-feng LIU hai-feng ma Xiao-ye FAN Xiao-ming ZHANG Qi Department of Cardiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

Background Insulin resistance（IR）is significantly associated with coronary artery disease and cardiovascular events in patients with or without type 2 diabetes *** study aimed to evaluate the influence of IR on long-term outcomes of patients undergoing percutaneous coronary intervention（PCI）with sirolimus-eluting stent（SES）*** A total of 467 consecutive patients undergoing SES-based PCI were divided into lR group（n=104）and non-IR group（n=363）.The patients were followed up for one *** rate of major adverse cardiac events（maCEs） including death, non-fatal myocardial infarction and recurrent angina pectoris was compared by the log-rank test,and the independent risk factors were identified by the Cox regression *** maCEs occurred more frequently,and cumulative survival rate was lower in the IR group than in the non-IR group during the follow-up （all P〈0.05）.IR was an independent risk factor for the occurrence of cardiac death and non-fatal myocardial infarction（OR=2176,95% CI=1.35-5.47,P=0.034）.Old age,diabetes,and multi-vessel disease were determinants for recurrent angina pectoris after PCI（P〈0.05）.Subgroup analysis revealed that IR（OR=3.35,95% CI=1.07-13.59,P=0.013）and multi-vessel disease（OR=2.19,95%CI=1.01-5.14,P=0.044）were independent risk predictors for recurrent angina pectoris in patients with diabetes after *** IR is associated with reduced maCE-free survival and remains an independent predictor for recurrent angina pectoris after PCI with SES implantation.

关键词： insulin resistance coronary artery disease sirolimus-eluting stent long-term prognosis

Study on trifluoromethanesulfonic acid-promoted synthesis of daidzein: Process optimization and reaction mechanism

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Chinese Journal of Chemical Engineering 2024年第7期71卷 132-139页

作者： hai Cao haibin Yang Yanxiong Fang Yuandi Zeng Xiaolan Cai Jingjing ma School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang 515200China

Daidzein has been widely used in pharmaceuticals,nutraceuticals,cosmetics,feed additives,*** preparation process and related reaction mechanism need to be further investigated.A cost-effective process for synthesizing daidzein was developed in this *** this article,a two-step synthesis of daidzein(Friedel–Crafts acylation and[5+1]cyclization)was developed via the employment of trifluoromethanesulfonic acid(TfOH)as an effective promoting *** effect of reaction conditions such as solvent,the amount of TfOH,reaction temperature,and reactant ratio on the conversion rate and the yield of the reaction,respectively,was systematically investigated,and daidzein was obtained in 74.0%isolated yield under optimal *** to the facilitating effect of TfOH,the Friedel–Crafts acylation was completed within 10 min at 90℃ and the[5+1]cyclization was completed within 180 min at 25℃.In addition,a possible reaction mechanism for this process was *** results of the study may provide useful guidance for industrial production of daidzein on a large scale.

关键词： Synthesis Optimal design Chemical processes Reaction mechanism