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干旱胁迫对栀子花叶性状及抗氧化酶活性的影响

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亚热带植物科学 2024年第2期53卷 120-127页

作者：陈清海泉州市城市森林公园发展中心福建泉州362000

为探究干旱胁迫对栀子Gardenia jasminoides植株生长、花叶性状及抗氧化酶活性的影响,采用‘灵地珍栀’扦插苗为试材,测定不同干旱胁迫程度下其株高增长量、地径增长量、相对叶绿素含量、花与叶性状的变化。结果表明,干旱胁迫显著降低... 详细信息

为探究干旱胁迫对栀子Gardenia jasminoides植株生长、花叶性状及抗氧化酶活性的影响,采用‘灵地珍栀’扦插苗为试材,测定不同干旱胁迫程度下其株高增长量、地径增长量、相对叶绿素含量、花与叶性状的变化。结果表明,干旱胁迫显著降低栀子株高和地径增长量,降低花直径、新增叶数、叶长、叶宽等指标,且随着干旱程度的加深,抑制效果愈加明显,但SPAD总体呈上升趋势,且随着干旱胁迫时间延长,栀子SOD活性总体上升,POD、CAT活性总体下降。干旱胁迫缩短了栀子单叶的生长周期,加速叶片成熟,抑制新叶的形成和生殖生长,打破了栀子叶片原有抗氧化酶之间的协同作用,以此降低能量和水分消耗,导致抗氧化还原失衡,自由基积累,膜脂过氧化加剧,栀子花、叶片变小变少。

关键词：栀子干旱胁迫生长花叶性状

Single-particle Entanglement and Its Application to Quantum Information Processing

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量子光学学报 2006年第B8期12卷 68-69页

作者： hai-woong Lee Department of Physics KAIST Daejeon 305-701 Korea

Is endoscopic ultrasonography essential for endoscopic resection of small rectal neuroendocrine tumors?

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World Journal of Gastroenterology 2017年第11期23卷 2037-2043页

作者： Su Bum park Dong Jun Kim Hyung Wook Kim Cheol woong Choi Dae Hwan Kang Su Jin Kim Hyeong Seok Nam Department of Internal Medicine Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsanGyeongsangnam-do 626-770South Korea

AIM To evaluate the importance of endoscopic ultrasonography(EUS) for small(≤ 10 mm) rectal neuroendocrine tumor(NET) *** Patients in whom rectal NETs were diagnosed by endoscopic resection(ER) at the Pusan National University Yangsan Hospital between 2008 and 2014 were included in this study. A total of 120 small rectal NETs in 118 patients were included in this study. Histologic features and clinical outcomes were analyzed, and the findings of endoscopy, EUS and histology were compared. RESULTS The size measured by endoscopy was not significantly different from that measured by EUS and histology(r = 0.914 and r = 0.727 respectively). Accuracy for the depth of invasion was 92.5% with EUS. No patients showed invasion of the muscularis propria or metastasis to the regional lymph nodes. All rectal NETswere classified as grade 1 and demonstrated an L-cell phenotype. Mean follow-up duration was 407.54 ± 374.16 d. No patients had local or distant metastasis during the follow-up periods. CONCLUSION EUS is not essential for ER in the patient with small rectal NETs because of the prominent morphology and benign behavior.

关键词： Neuroendocrine tumor Small Rectal Endoscopic ultrasonography Histology Endoscopy

Assessment of disease activity by fecal immunochemical test in ulcerative colitis

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World Journal of Gastroenterology 2016年第48期22卷 10617-10624页

作者： Dae Gon Ryu Hyung Wook Kim Su Bum park Dae Hwan Kang Cheol woong Choi Su Jin Kim Hyeong Seok Nam Department of Internal Medicine Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital

AIM To evaluate the efficacy of quantitative fecal immunochemical test(FIT) as biomarker of disease activity in ulcerative colitis(UC).METHODS Between February 2013 and November 2014, a total of 82 FIT results, obtained in conjunction with colonoscopies, were retrospectivelyevaluated for 63 patients with UC. The efficacy of FIT for evaluation of disease activity was compared to colonoscopic findings. Quantitative fecal blood with automated equipment examined from collected feces. Endoscopic disease severity were assessed using the Mayo endoscopic subscore(MES) classification. The extent of disease were classified by proctitis(E1), left sided colitis(E2), and extensive colitis(E3). Clinical activity were subgrouped by remission or *** All of 21 patients with MES 0 had negative FIT( 134.89 ng/m L. The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and accuracy of negative FIT about mucosal healing were 73.33%, 81.82%, 91.49%, 51.43% and 73.17%, respectively. The sensitivity, specificity, PPV, NPV and accuracy of predictive value of positive FIT(cutoff value > 100 ng/mL) about active disease status were 45.45%, 93.33%, 71.43%, 82.35%and 26.83%, respectively. Among patients with clinical remission, FIT was negative in 31(81.6%) of 38 cases, with a mean fecal hemoglobin concentration of 6.12 ng/mL(range, negative to 80.9 ng/mL) for this group of patients. Among patients with clinical active disease, FIT was negative in 16(36.4%) out of 44 cases, with a mean fecal hemoglobin concentration > 167.4 ng/mL for this group of patients. FIT was positively correlated with endoscopic activity(r = 0.626, P < 0.01) and clinical activity(r = 0.496, P < 0.01). But, FIT did not correlate with the extent of disease(r =-0.047, P = 0.676)CONCLUSION Quantitative FIT can be a non-invasive and effective biomarker for evaluation of clinical and endoscopic activity in UC, but not

关键词： Ulcerative colitis Fecal immunochemical test Mayo endoscopic subscore Biomarker Disease activity

Efficacy and safety of limited endoscopic sphincterotomy before self-expandable metal stent insertion for malignant biliary obstruction

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World Journal of Gastroenterology 2017年第9期23卷 1627-1636页

作者： Hyeong Seok Nam Dae Hwan Kang Hyung Wook Kim Cheol woong Choi Su Bum park Su Jin Kim Dae Gon Ryu Department of Internal Medicine Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsan-siGyeongsangnam-do 50612South Korea

To evaluate the safety and efficacy of limited endoscopic sphincterotomy (ES) before placement of self-expandable metal stent (SEMS).METHODSThis was a retrospective analysis of 244 consecutive patients with unresectable malignant biliary obstruction, who underwent placement of SEMSs following limited ES from December 2008 to February 2015. The diagnosis of malignant biliary obstruction and assessment of patient eligibility for the study was established by a combination of clinical findings, laboratory investigations, imaging and pathological results. All patients were monitored in the hospital for at least 24 h following endoscopic retrograde cholangio pancreatography (ERCP). The incidence of immediate or early post-ERCP complications such as post-ERCP pancreatitis (PEP) and bleeding related to limited ES were considered as primary outcomes. Also, characteristics and complications according to the cancer type were *** the 244 patients included, the underlying diagnosis was cholangiocarcinoma in 118 patients, pancreatic cancer in 79, and non-pancreatic or non-biliary malignancies in the remaining 47 patients. Early post-ERCP complications occurred in 9 patients (3.7%), with PEP in 7 patients (2.9%; mild, 6; moderate, 1) and mild bleeding in 2 patients (0.8%). There was no significant association between the incidence of post-ERCP complications and the type of malignancy (cholangiocarcinoma vs pancreatic cancer vs others, P = 0.696) or the type of SEMS used (uncovered vs covered, P = 1.000). Patients who had more than one SEMS placed at the first instance were at a significantly higher risk of post-ERCP complications (one SEMS vs two SEMS, P = 0.031). No other factors were predictive of post-ERCP *** ES is feasible and safe, and effectively facilitates the placement of SEMS, without any significant risk of PEP or severe bleeding.

关键词： Endoscopic sphincterotomy Endoscopic retrograde cholangio pancreatography Complications Pancreatitis Bleeding Cholestasis Self-expandable metal stent

考虑软弱夹土层的预应力管桩施工影响因素分析

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建筑技术 2024年第19期55卷 2404-2407页

作者：王海宁中国安能集团第二工程局有限公司南昌330000

预应力管桩具有单桩承载力强、适应性强等优势,在越来越多的工程被广泛应用。本研究以河南某产业园实际工程为例,基于有限元软件ABAQUS构建了土体(欧拉体)–桩基(实体)三维数值模型(CEL法),考虑实际工程沉桩过程中预应力管桩不同的桩距... 详细信息

预应力管桩具有单桩承载力强、适应性强等优势,在越来越多的工程被广泛应用。本研究以河南某产业园实际工程为例,基于有限元软件ABAQUS构建了土体(欧拉体)–桩基(实体)三维数值模型(CEL法),考虑实际工程沉桩过程中预应力管桩不同的桩距及数量,对比分析软弱夹土层应力与桩基沉桩时间的响应规律。研究表明:桩间软弱土层的最大应力呈现出随着桩距的增大而逐渐减少的规律;随着桩的数量增加,在一定程度上增加了桩间软弱土层的最大应力。本研究可为软弱夹土层场地下预应力管桩的施工关键技术提供理论依据。

关键词：预应力管桩软弱夹土层 CEL方法数值模拟有限元三维数值模型

Associated factors for a hyperechogenic pancreas on endoscopic ultrasound

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World Journal of Gastroenterology 2010年第34期16卷 4329-4334页

作者： Cheol woong Choi Gwang Ha Kim Dae Hwan Kang Hyung Wook Kim Dong Uk Kim Jeong Heo Geun Am Song Do Youn park Suk Kim Department of Internal Medicine Pusan National University School of Medicine and the Medical Research Institute Pusan National University Hospital Department of Internal Medicine Pusan National University School of Medicine and the Medical Research Institute Department of Pathology Pusan National University School of Medicine and the Medical Research Institute Department of Radiology Pusan National University School of Medicine and the Medical Research Institute

AIM: To identify the associated risk factors for hyperechogenic pancreas (HP) which may be observed on endoscopic ultrasound (EUS) and to assess the relationship between HP and obesity. METHODS: From January 2007 to December 2007, we prospectively enrolled 524 consecutive adults who were scheduled to undergo EUS. Patients with a history of pancreatic disease or with hepatobiliary or advanced gastrointestinal cancer were excluded. Finally,284 patients were included in the analyses. We further analyzed the risk of HP according to the categories of visceral adipose tissue (VAT) and subcutaneous adipose tissue in 132 patients who underwent abdominal computed tomography scans. RESULTS: On univariate analysis, age older than 60 years, obesity (body mass index > 25 kg/m 2 ), fatty liver, diabetes mellitus, hypertension and hypercholesterolemia were identified as risk factors associated with HP (P < 0.05). On multivariate analysis, fatty liver [P = 0.008, odds ratio (OR) = 2.219], male gender (P = 0.013, OR = 2.636), age older than 60 years (P = 0.001, OR = 2.874) and hypertension (P = 0.044, OR = 2.037) were significantly associated with HP. In the subgroup analysis, VAT was a statistically significant risk factor for HP (P = 0.010, OR = 5.665, lowest quartile vs highest quartile). CONCLUSION: HP observed on EUS was associated with fatty liver, male gender, age older than 60 years, hypertension and VAT.

关键词： Endoscopic Ultrasound Hyperechogenic pancreas Obesity

Sperm hyaluronidase is critical to mammals'fertilization for its ability to disperse cumulus-oocyte complex layer

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Asian Journal of Andrology 2022年第4期24卷 411-415页

作者： Dong-Won Seol Sang Hoon Joo Young-Hyun Kim Bong-Seok Song Bo-woong Sim Sun-Uk Kim Soojin park Gabbine Wee Ekyune Kim Laboratory Animal Center Daegu-Gyeongbuk Medical Innovation Foundation(DGMIF)Daegu 41061Korea College of Pharmacy Catholic University of DaeguGyeongbuk 38430Korea National Primate Research Center(NPCR) Korea Research Institute of Bioscience and BiotechnologyChungcheongbuk-do 28116Korea Futuristic Animal Resource and Research Center Korea Research Institute of Bioscience and BiotechnologyChungcheongbuk-do 28116Korea Department of Biochemistry and Molecular Biology Melvin and Bren Simon Comprehensive Cancer CenterIndiana University School of MedicineIndianapolisIN 46202USA

Glycosylphosphatidylinositol-anchored sperm hyaluronidases have long been believed to assist in sperm penetration through the cumulus-oocyte complex(COC);however,their role in mammalian fertilization remains ***,we have shown that hyaluronidase 5(Hyal5)/Hyal7 double-knockout(dKO)mice produce significantly fewer offspring than their wild-type(WT)counterparts because of defective COC *** infertility is mainly caused by a low sperm *** can be further exacerbated by the deficiency of sperm hyaluronidase,which disperses the cumulus cells of the outer layer of the *** the current study,we evaluated the effects of a low count of Hyal-deficient sperm and conditions of ovulated oocytes on the fertilization rate using a mouse *** results demonstrated that a low sperm count further decreases the in vitro fertilization(IVF)rate of Hyal-deficient dKO *** addition,the dKO spermatozoa resulted in a fertilization rate of 12.5%upon fertilizing COCs with a thick cumulus layer,whereas the IVF rate was comparable to that of WT spermatozoa when oocytes with a thin or no cumulus layer were ***,we proved that the IVF rate of dKO spermatozoa could be recovered by adding rat spermatozoa as a source of sperm *** results suggest that a deficiency of proteins involved in fertilization,such as sperm hyal,has a vital role in fertilization.

关键词： HYAL5 HYAL7 cumulus-oocyte complex fertilization infertility sperm hyaluronidase

具身认知视角下普达措国家公园游客视听体验研究

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江苏商论 2024年第6期 62-70页

作者：王璐柴海燕武汉学院管理学院湖北武汉430212

作为首批国家公园体制试点之一,普达措经验对国家公园体制建设具有意义重大。本文基于OTA游客点评,综合应用案例分析、内容分析等手段对普达措游客多感官体验进行研究。研究结论认为,游客在普达措的游览体验是多感官共同参与的过程,多... 详细信息

作为首批国家公园体制试点之一,普达措经验对国家公园体制建设具有意义重大。本文基于OTA游客点评,综合应用案例分析、内容分析等手段对普达措游客多感官体验进行研究。研究结论认为,游客在普达措的游览体验是多感官共同参与的过程,多维度感官体验共同构成了游客的感官印象;视觉、听觉体验是游客最主要感官体验,嗅、味、触是辅助的感官印象;游客的感官体验具有明显的时间性;游客在普达措的感官体验会进一步促进游客的认知加工。基于此提出普达措的营销建议:打造水陆空立体游览路线,丰富观览视角;体验安静为主,构建特色声音标识;增加嗅味触体验项目,加深游客的感官记忆;挖掘普达措的精神内涵,提升公园文化附加值。

关键词：具身认知普达措国家公园多感官体验感官营销