检索结果-南通市图书馆

Dynamics analysis in a tumor-immune system with chemotherapy

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2021年第5期30卷 673-681页

作者： hai-ying liu Hong-Li Yang Lian-Gui Yang School of Mathematical Sciences Inner Mongolia UniversityHohhot 010021China

An ordinary differential equation(ODE)model of tumor growth with the effect of tumor-immune interaction and chemotherapeutic drug is presented and *** analyzing the existence and stability of equilibrium points,the dynamic behavior of the system is discussed *** chaotic dynamics can be obtained in our model by equilibria analysis,which show the existence of chaos by calculating the Lyapunov exponents and the Lyapunov dimension of the ***,the action of the infusion rate of the chemotherapeutic drug on the resulting dynamics is investigated,which suggests that the application of chemotherapeutic drug can effectively control tumor ***,in the case of high-dose chemotherapeutic drug,chemotherapy-induced effector immune cells damage seriously,which may cause treatment failure.

关键词： dynamical model tumor-immune system chemotherapy chaos

Multi-Scale Deep Cascade Bi-Forest for Electrocardiogram Biometric Recognition

在线全文

学校读者我要写书评

暂无评论

Journal of Computer Science & Technology 2021年第3期36卷 617-632页

作者： Yu-Wen Huang Gong-Ping Yang Kui-Kui Wang hai-ying liu Yi-Long Yin School of Software Shandong UniversityJinan 250101China School of Computer Heze UniversityHeze 274015China Department of Computer Engineering Changji UniversityChangji 831100China

Electrocardiogram(ECG)biometric recognition has emerged as a hot research topic in the past *** some promising results have been reported,especially using sparse representation learning(SRL)and deep neural network,robust identification for small-scale data is still a *** address this issue,we integrate SRL into a deep cascade model,and propose a multi-scale deep cascade bi-forest(MDCBF)model for ECG biometric *** design the bi-forest based feature generator by fusing L1-norm sparsity and L2-norm collaborative representation to efficiently deal with *** we propose a deep cascade framework,which includes multi-scale signal coding and deep cascade *** the former,we design an adaptive weighted pooling operation,which can fully explore the discriminative information of segments with low *** deep cascade coding,we propose level-wise class coding without backpropagation to mine more discriminative *** experiments are conducted on four small-scale ECG databases,and the results demonstrate that the proposed method performs competitively with state-of-the-art methods.

关键词： electrocardiogram(ECG)biometric recognition small-scale data deep cascade bi-forest multi-scale division sparse representation learning

THREE-DIMENSIONAL NUMERICAL MODELLING OF SUBMERGED DIKE ALIGNMENT IN CURVED ESTUARINE CHANNEL

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2005年第5期17卷 601-606页

作者： ZHENG Jin-hai liu ying-qi YAN Yi-xin ZHU Yu-liang Research Institute of Coastal and Ocean Engineering Hohai University Nanjing 210098 China

Submerged dikes were frequently built in curved estuarine channels to improve navigational conditions. A three-dimensional numerical model of tidal motions was developed to simulate flows through the submerged dike alignment in curved estuarine reach of complex bathymetry on the basis of satisfactory calibrations. Through the analysis of the morphological characteristics of the curved channel of the Huangpu River mouth in the Yangtze River Delta, a submerged dike alignment project was examined. The effect of the navigation channel improvement project and its influence on the flow regimes, the navigational conditions, the flood control and the operating conditions of harbours within the adjacent water area were evaluated, and the technical feasibility of the navigation channel improvement scheme was demonstrated.

关键词： submerged dike alignment three-dimensional numerical model curved estuarine channel morphological analysis

Potential dynamic analysis of tumor suppressor p53 regulated by Wip1 protein

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2020年第6期29卷 577-582页

作者： Nan liu Dan-Ni Wang hai-ying liu Hong-Li Yang Lian-Gui Yang School of Mathematical Sciences Inner Mongolia UniversityHohhot 010021China

The tumor suppressor p53 plays a key role in protecting genetic integrity. Its dynamics have important physiological significance, which may be related to the cell fate. Previous experiments have shown that the wild-type p53-induced phosphatase 1(Wip1) protein could maintain p53 oscillation. Therefore, we add Wip1 to remodel the p53 network. Firstly,we use the binomial τ-leap algorithm to prove our model stable under internal noise. Then, we make a series of bifurcation diagrams, that is, p53 levels as a function of p53 degradation rate at different Wip1 generation rates. The results illustrate that Wip1 is essential for p53 oscillation. Finally, a two-dimensional bifurcation diagram is made and the stability of some p53 dynamics under external noise is analyzed by potential landscape. Our results may have some implications for artificially interfering with p53 dynamics to achieve tumor suppression.

关键词： Wip1 p53-dynamics oscillation

Guillain-Barre Syndrome Complicated on Postoperation on Renal Carcinoma and Meningioma

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第9期131卷 1122-1123页

作者： Shuai Xu Fen Peng Yang-Shuo Wang Shu Li hai-ying liu Department of Spinal Surgery Peking University People's Hospital Peking University Beijing 100044 China Department of Dermatology Peking University People's Hospital Peking University Beijing 100044 China Department of Neurosurgery Peking University People's Hospital Peking University Beijing 100044 China Department of Critical Care Medicine Peking University People's Hospital Peking University Beijing 100044 China

To the Editor：Guillain-Barre syndrome （GBS） is an autoimmune disease on the injury of peripheral nerve myelin proteins or axon,of which the acute motor axonal neuropathy （AMAN） as a subtype is of infrequent and an extremely low incidence after the *** case was reported on the successful treatment of severe GBS （AMAN） on postoperation of renal carcinoma and meningioma,aiming to provide successful treatment experience in such severe cases.

关键词：

Hepatic injury induced by carbon dioxide pneumoperitoneum in experimental rats

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第24期15卷 3060-3064页

作者： Gui-Sen Xu He-Nian liu Jun Li Xiao-Ling Wu Xue-Mei Dai ying-hai liu Department of Anesthesia General Hospital of Chengdu Military Command Area Chengdu 610083 Sichuan Province China Department of Digestion General Hospital of Chengdu Military Command Area Chengdu 610083 Sichuan Province China

AIM： To observe the hepatic injury induced by carbon dioxide pneumoperitoneum in rats and to explore its potential mechanism.METHODS： Thirty healthy male SD rats were randomly divided into control group （n = 10）, 0 h experimental group （n = 10） and 1 h experimental group （n = 10） after sham operation with carbon dioxide pneumoperitoneum. Histological changes in liver tissue were observed with hematoxylineosin staining. Liver function was assayed with an automatic biochemical analyzer. Concentration of malonyldialdehyde （MDA） and activity of superoxide dismutase （SOD） were assayed by colorimetry. Activity of adenine nucleotide translocator in liver tissue was detected with the atractyloside-inhibitor stop technique. Expression of hypoxia inducible factor-1 （HIF-1） mRNA in liver tissue was detected with in situ hybridization.RESULTS： Carbon dioxide 60 min could induce liver pneumoperitoneum for injury in rats. Alanine aminotransferase and aspartate aminotransferase were 95.7 ± 7.8 U/L and 86.8 ± 6.9 U/L in 0 h experimental group, and 101.4 ± 9.3 U/L and 106.6 ±8.7 U/L in 1 h experimental group. However, no significant difference was found in total billirubin, albumin, and pre-albumin in the three groups. In 0 h experimental group, the concentration of MDA was 9.83 ±2.53 μmol/g in liver homogenate and 7.64 ± 2.19 μmol/g in serum respectively, the activity of SOD was 67.58±9.75 nu/mg in liver and 64.47 ± 10.23 nu/mg in serum respectively. In 1 h experimental group, the concentration of MDA was 16.57±3.45 μmol/g in liver tissue and 12.49 ±4.21 μmol/g in serum respectively, the activity of SOD was 54.29 ±7.96 nu/mg in liver tissue and 56.31 ±9.85 nu/mg in serum respectively. The activity of ANT in liver tissue was 9.52 ± 1.56 in control group, 6.37± 1.33 in 0 h experimental group and 7.2 8±1.45 （10^-9 mol/min per gram protein） in 1 h experimental group, respectively. The expression of HIF-1 mRNA in liver tissue was not detected in control group, and its optical densit

关键词： Carbon dioxide pneumoperitoneum Hepatic injury Rat Anoxia Laparoscopic operation

Assessment of functional prognosis of anterior cruciate ligament reconstruction in athletes based on a body shape index

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第19期11卷 4567-4578页

作者： Yun-Jun Wang Jun-Chang Zhang Yu-Ze Zhang ying-hai liu Institutes of Biomedical Sciences Shanxi UniversityTaiyuan 030006Shanxi ProvinceChina Department of Orthopedics First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND A healthy body shape is essential to maintain athletes’sports *** present,little is known about the effect of athletes’body shape on anterior cruciate ligament reconstruction(ACLR).Moreover,the relationship between body shape and variables such as knee joint function after operation and return to the field has not been well *** To verify the relationship between a body shape index(ABSI)and the functional prognosis of the knee after ACLR in athletes with ACL *** We reviewed 76 athletes with unilateral ACL ruptures who underwent ACLR surgery in the First Hospital of Shanxi Medical University between 2017 and 2020,with a follow-up period of more than 24 ***,all populations were divided into a High-ABSI group(ABSI>0.835,n=38)and a Low-ABSI group(ABSI<0.835,n=38)based on the arithmetic median(0.835)of ABSI *** primary exposure factor was ABSI,and the outcome indicators were knee function scores as well as postoperative *** correlation between ABSI and postoperative knee function scores and postoperative complications after ACLR were analyzed using multifactorial logistic *** The preoperative knee function scores of the two groups were *** surgery and postoperative rehabilitation exercises,range of motion(ROM)compliance rate,Lysholm score,and Knee Injury and Osteoarthritis Outcome Score of the two groups gradually increased,whereas the quadriceps atrophy index gradually *** knee function scores were higher in the Low-ABSI group than in the High-ABSI group at the 24-mo postoperative follow-up(P<0.05).In multifactorial logistic regression,ABSI was a risk factor of low knee joint function score after surgery,specifically low ROM scores(odds ratio[OR]=1.31,95%confidence interval[CI][1.10-1.44];P<0.001),low quadriceps atrophy index(OR=1.11,95%CI[0.97-1.29];P<0.05),low Lysholm scores(OR=2.34,95%CI[1.78-2.94];P<0.001),low symptoms(OR=1.14,95%CI[1.02-1.34];P<0.05),low activity of daily

关键词： A body shape index Anterior cruciate ligament reconstruction Athletes Multifactorial logistic regression Obesity

Zebrafish imaging and two-photon fluorescence imaging using ZnSe quantum dots

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2021年第4期30卷 247-251页

作者： Nan-Nan Zhang Li-Ya Zhou Xiao liu Zhong-Chao Wei hai-ying liu Sheng Lan Zhao Meng hai-Hua Fan Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices School of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006China School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China Guangdong Women and Children Hospital Guangzhou 510000China

This study is to report a ZnSe quantum dot with a large two-photon absorption cross section and good biocompatibility,which can be used in *** emission at 410 nm is observed in the quantum dot under 760-nm laser *** biocompatible quantum dots exhibit a two-photon cross-section of 9.1×105 GM(1 GM=10-50 cm4·s/photon).Two-photon excited laser scanning microscopic images show that cells co-cultured with ZnSe quantum dots are found in the blue channel at a fluorescence intensity that is 14.5 times that of control cells not cocultured with quantum *** incubating zebrafish larvae with ZnSe quantum dots for 24 h,the fluorescence intensity of the yolk sac stimulated by ultraviolet light is 2.9 times that of the control *** proposed material shows a great potential application in biological imaging.

关键词： ZnSe quantum dots two-photon absorption biological imaging zebrafish

Solar broadband metamaterial perfect absorber based on dielectric resonant structure of Ge cone array and InAs film

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2021年第11期30卷 325-330页

作者： Kuang-Ling Guo Hou-Hong Chen Xiao-Ming Huang Tian-Hui Hu hai-ying liu Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices School for Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006China

The broadband metamaterial perfect absorber has been extensively studied due to its excellent characteristics and promising application *** this work a solar broadband metamaterial perfect absorber is proposed based on the structure of the germanium(Ge)cone array and the indium arsenide(InAs)dielectric film on the gold(Au)*** results show that the absorption covers the whole ultraviolet-visible and near-infrared *** the case of A>99%,the absorption bandwidth reaches up to 1230 nm with a wavelength range varied from 200 nm to 1430 *** proposed absorber is able to absorb more than 98.7%of the solar energy in a solar spectrum from 200 nm to 3000 *** electromagnetic dipole resonance and the high-order modes of the Ge cone couple strongly to the incident optical field,which introduces a strong coupling with the solar radiation and produces an ultra-broadband *** absorption spectrum can be feasibly manipulated via tuning the structural parameters,and the polarization insensitivity performance is particularly *** proposed absorber can possess wide applications in active photoelectric effects,thermion modulators,and photoelectric detectors.

关键词： metamaterial electromagnetic resonance perfect absorber solar broadband absorption`