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Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression

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World Journal of Psychiatry 2025年第1期15卷 32-36页

作者： Min Xu hai-Ying jin Feng-Li Sun Wei-Dong jin Department of Psychiatry Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Psychiatry Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Department of Psychiatry Zhejiang Provincial Mental Health CenterHangzhou 311122Zhejiang ProvinceChina

Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent ***,many adolescent depression treatment guidelines still recommend the use of antidepressants,especially specific serotonin re-uptake *** studies have suggested that antidepressants have little therapeutic effect but many side effects,such as switching to mania,suicide,and non-suicidal self injury(NSSI),in the treatment of child and adolescent *** the process of developing guidelines,drug recommendations should not only focus on impro-ving symptoms,but they should also consider potential side *** review discusses the serious side effects of antidepressants,including switching to mania,suicide,and NSSI.

关键词： Child depression Adolescent depression Antidepressant Switch Suicide Non-suicidal self injury

Towards trustworthy blockchain systems in the era of “Internet of value”: development, challenges, and future trends

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Science China(Information Sciences) 2022年第5期65卷 250-260页

作者： hai jin Jiang XIAO National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and TechnologyHuazhong University of Science and Technology

Since the advent of cryptocurrencies such as Bitcoin, blockchain, as their underlying technologies,has drawn a massive amount of attention from both academia and the industry. This ever-evolving technology inherits the “genes” of distributed systems, offering significant advantages of immutability, transparency,auditability, and tamper-resistance. These benefits help blockchain re-establish public confidence, and hold the significant promise of reliable information sharing and value transfer. Therefore, blockchain has become the foundation of crucial strategic deployments in countries across the world, and the fundamental basis for building the next generation Web 3.0 — “Internet of value”. In this article, we will start with unraveling the essential ingredients of blockchain technology, and showing the characteristics of each of these ingredients in the context of distributed systems. We will then present the core technical challenges that need to be addressed prior to unleashing its full potential, including its performance, scalability, and cross-chain interoperability. Finally, we will introduce the recent developments of blockchain systems, and discuss the future trends of the blockchain ecosystem.

关键词： blockchain distributed systems internet of value challenges development

Bi-Frobenius Algebra Structures on Quantum Complete Intersections

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1481-1504页

作者： hai jin Pu ZHANG School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai 200240P.R.China

This paper is to look for bi-Frobenius algebra structures on quantum complete intersections over field *** find a class of comultiplications,such that if√−1∈k,then a quantum complete intersection becomes a bi-Frobenius algebra with comultiplication of this form if and only if all the parameters qij=±***,it is proved that if√−1∈k then a quantum exterior algebra in two variables admits a bi-Frobenius algebra structure if and only if the parameter q=±√*** if−1/∈k,then the exterior algebra with two variables admits no bi-Frobenius algebra *** prove that the quantum complete intersections admit a bialgebra structure if and only if it admits a Hopf algebra structure,if and only if it is commutative,the characteristic of k is a prime p,and every ai a power of *** also provides a large class of examples of bi-Frobenius algebras which are not bialgebras(and hence not Hopf algebras).In commutative case,other two comultiplications on complete intersection rings are given,such that they admit non-isomorphic bi-Frobenius algebra structures.

关键词： Bi-Frobenius algebras coalgebras bialgebras Hopf algebras quantum complete intersections quantum exterior algebras

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A Time-Marching Throughflow Model and its Application in Transonic Axial Compressor

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Journal of Thermal Science 2010年第6期19卷 519-525页

作者： jin hai-liang jin Dong-hai LI Xiao-juan GUI Xing-min Aeroengine Numerical Simulation Research Center Beihang University Beijing China The College of Engineering Peking University Beijing China

A throughflow model based on the time-marching finite volume approach is described in this paper. The governing equations are derived by circumferentially averaging the three-dimensional Navier-Stokes equations neglecting the circumferentially non-uniform and viscous terms. An inviscid blade force model similar to the Large-particle method is derived. The viscous blade force has been modeled by the distributed loss model. The convective fluxes of the governing equation are discretized with the Edward’s low-diffusion flux-splitting (LDFSS) scheme. And a point-iterative Symmetric Gauss-Seidel (SGS) scheme is used in the temporal discretization. The throughflow model has been applied to the NASA Rotor 67 and a high-load transonic fan stage ATS-2. The reasonable good agreements with the experiments and the 3D viscous computations show the potential of the method.

关键词： throughflow model time marching transonic axial compressor

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Answering reachability queries with ordered label constraints over labeled graphs

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Frontiers of Computer Science 2024年第1期18卷 105-117页

作者： Daoliang HE Pingpeng YUAN hai jin National Engineering Research Center for Big Data Technology and System Services Computing Technology and System LabCluster and Grid Computing LabSchool of Computer Science&TechnologyHuazhong University of Science and TechnologyWuhan 430074China

Reachability query plays a vital role in many graph analysis *** researches proposed many methods to efficiently answer reachability queries between vertex *** many real graphs are labeled graph,it highly demands Label-Constrained Reachability(LCR)query inwhich constraint includes a set of labels besides vertex *** researches proposed several methods for answering some LCR queries which require appearance of some labels specified in constraints in the *** that constraint may be a label set,query constraint may be ordered labels,namely OLCR(Ordered-Label-Constrained Reachability)queries which retrieve paths matching a sequence of ***,no solutions are available for ***,we propose DHL,a novel bloom filter based indexing technique for answering OLCR *** can be used to check reachability between vertex *** the answers are not no,then constrained DFS is ***,we employ DHL followed by performing constrained DFS to answer OLCR *** show that DHL has a bounded false positive rate,and it's powerful in saving indexing time and *** experiments on 10 real-life graphs and 12 synthetic graphs demonstrate that DHL achieves about 4.8-22.5 times smaller index space and 4.6-114 times less index construction time than two state-of-art techniques for LCR queries,while achieving comparable query response *** results also show that our algorithm can answer OLCR queries effectively.

关键词： graph ordered-label-constrained reachability partial index bloom filter query processing

FunctionFlow:coordinating parallel tasks

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Frontiers of Computer Science 2019年第1期13卷 73-85页

作者： Xuepeng FAN Xiaofei LIAO hai jin Services Computing Technology and System Lab (SCTS)&Cluster and Grid Computing Lab (CGCL) School of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China

With the growing allel programming,nowadays popularity of task-based partask-parallel programming libraries and languages are still with limited support for coordinating parallel *** limitation forces programmers to use additional independent components to coordinate the parallel tasks -the components can be third-party libraries or additional components in the same programming library or ***,mixing tasks and coordination components increase the difficulty of task-based programming,and blind schedulers for understanding tasks'dependencies. In this paper,we propose a task-based parallel programming library,Function Flow,which coordinates tasks in the purpose of avoiding additional independent coordination ***,we use dependency expression to represent ubiquitous tasks'*** key idea behind dependency expression is to use && for both task's termination and Ⅱ for any task termination,along with the combination of dependency ***,as runtime support,we use a lightweight representation for dependency expression. Also,we use suspended-task queue to schedule tasks that still have prerequisites to run. Finally,we demonstrate Function Flow's effectiveness in two aspects,case study about implementing popular parallel patterns with FunctionFIow,and performance comparision with state-of-the-art practice,*** demonstration shows that FunctionFIow can generally coordinate parallel tasks without involving additional components,along with comparable performance with TBB.

关键词： task parallel programming tasks dependency FunctionFlow coordination patterns

Saudi cloud infrastructure: a security analysis

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Science China(Information Sciences) 2017年第12期60卷 152-164页

作者： Wahid RAJEH hai jin Deqing ZOU Services Computing Technology and System Lab Big Data Technology and System LabCluster and Grid Computing Lab School of Computer Science and TechnologyHuazhong University of Science and Technology School of Computers and Information Technology University of Tabuk

The growing demand and dependence upon cloud services have garnered an increasing level of threat to user data and security. Some of such critical web and cloud platforms have become constant targets for persistent malicious attacks that attempt to breach security protocol and access user data and information in an unauthorized manner. While some of such security compromises may result from insider data and access leaks, a substantial proportion continues to remain attributed to security flaws that may exist within the core web technologies with which such critical infrastructure and services are developed. This paper explores the direct impact and significance of security in the Software Development Life Cycle(SDLC) through a case study that covers some 70 public domain web and cloud platforms within Saudi Arabia. Additionally, the major sources of security vulnerabilities within the target platforms as well as the major factors that drive and influence them are presented and discussed through experimental evaluation. The paper reports some of the core sources of security flaws within such critical infrastructure by implementation with automated security auditing and manual static code analysis. The work also proposes some effective approaches, both automated and manual, through which security can be ensured through-out the SDLC and safeguard user data integrity within the cloud.

关键词： cloud security vulnerability detection web security Saudi infrastructure cloud service

Hybrid followee recommendation in microblogging systems

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Science China(Information Sciences) 2017年第1期60卷 21-34页

作者： Hanhua CHEN hai jin Xiaolong CUI Services Computing Technology and System Laboratory Big Data Technology and System LaboratoryCluster and Grid Computing Laboratory School of Computer Science and TechnologyHuazhong University of Science and Technology

Followee recommendation plays an important role in information sharing over microblogging platforms. Existing followee recommendation schemes adopt either content relevance or social information for followee ranking, suffering poor performance. Based on the observation that microblogging systems have dual roles of social network and news media platform, we propose a novel followee recommendation scheme that takes into account the information sources of both tweet contents and the social structures. We set up a linear weighted model to combine the two factors and further design a simulated annealing algorithm to automatically assign the weights of both factors in order to achieve an optimized combination of them. We conduct comprehensive experiments on real-world datasets collected from Sina Weibo, the largest microblogging system in China. The results demonstrate that our scheme provides a much more accurate followee recommendation for a user compared to existing schemes.

关键词： online social networks microblogging followee recommendation simulated annealing ranking

Theory and methodology of research on cloud security

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Science China(Information Sciences) 2016年第5期59卷 15-17页

作者： hai jin Weiqi DAI Deqing ZOU Services Computing Technology and System Lab Big Data Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Technology Huazhong University of Science and Technology

Cloud computing is a model for enabling ubiquitous,convenient,on-demand access to a shared pool of configurable computing *** to Gartner’s survey,cloud computing has been at the head of a list of the top ten IT strategic technologies for some *** computing is currently undergoing vigorous development and promotion by many leading Chinese and foreign enterprises,and it has become the basis for a new

关键词： TPM Theory and methodology of research on cloud security