检索结果-南通市图书馆

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng hai-Hui jiang Hui-Li Kang Yi jiang Hua-Wei Zhang Xiao-Mei Song Yu-Ze Li Wen-Li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Static and Dynamic Mechanics Analysis on Artificial Hip Joints with Different Interface Designs by the Finite Element Method

引用

Journal of Bionic Engineering 2007年第2期4卷 123-131页

作者： hai-bo jiang College of Mechanic and Electrical Engineering China University of Mining and Technology Xuzhou 221008 P. R. China

Four different structural models of artificial joints were developed and the finite element method （FEM） was employed to investigate their mechanical characteristics under static and dynamic conditions. The materials used in the FEM calculation were ultra-high molecular weight polyethylene （UHMWPE）, 316L stainless steel, CoCrMo alloy and Ti6A14V alloy. The stress distribution, strain, and elastic deformation under static and dynamic conditions were obtained. Analysis and comparison of the ~alculation results of different models were conducted. It is shown that with the same parameters the model of a metallic femur head covered with an artificial cartilage layer is more similar to the structure of the natural human joint and its mechanical characteristics are the best of the four models.

关键词： finite element analysis stress articular joint

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CONSTRUCTION METHOD OF KNOWLEDGE MAP BASED ON DESIGN PROCESS

引用

Chinese Journal of Mechanical Engineering 2007年第3期20卷 98-104页

作者： SU hai jiang Zuhua Department of Industrial Engineering ＆ Management Shanghai Jiaotong University Shanghai 200240 China

Due to the increasing amount and complexity of knowledge in product design, the know-ledge map based on design process is presented as a tool to reuse product design process, promote the product design knowledge sharing. The relationship between design task flow and knowledge flow is discussed; A knowledge organizing method based on design task decomposition and a visualization method to support the knowledge retrieving and sharing in product design are proposed. And a knowledge map system to manage the knowledge in product design process is built with Visual C＋＋ and SVG. Finally, a brief case study is provided to illustrate the construction and application of knowledge map in fuel pump design.

关键词： Knowledge map Knowledge management Design process Fuel pump

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The expanding vulnerabilities of being UTXless

引用

Signal Transduction and Targeted Therapy 2019年第1期4卷 564-565页

作者： hai jiang State Key Laboratory of Cell Biology CAS Center for Excellence in Molecular Cell SciencesShanghai Institute of Biochemistry and Cell BiologyChinese Academy of Sciences320 Yue-yang RoadShanghai 200031China

In a recent study.1 published in Signal Transduction and Targeted Therapy,*** Liu and collaborators report that the differentiation block in UTX-null leukemia cells can be reverted by an LSD1 inhibitor,highlighting ad... 详细信息

关键词： expanding Therapy UTX

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Indirect Adaptive Fuzzy and Impulsive Control of Nonlinear Systems

引用

International Journal of Automation and computing 2010年第4期7卷 484-491页

作者： hai-Bo jiang School of Mathematics Yancheng Teachers University Yancheng 224002 PRC

The problem of indirect adaptive fuzzy and impulsive control for a class of nonlinear systems is investigated. Based on the approximation capability of fuzzy systems, a novel adaptive fuzzy and impulsive control strategy with supervisory controller is developed. With the help of a supervisory controller, global stability of the resulting closed-loop system is established in the sense that all signals involved are uniformly bounded. Furthermore, the adaptive compensation term of the upper bound function of the sum of residual and approximation error is adopted to reduce the effects of modeling error. By the generalized Barbalat＇s lemma, the tracking error between the output of the system and the reference signal is proved to be convergent to zero Asymptotically. Simulation results illustrate the effectiveness of the proposed approach.

关键词： Fuzzy control adaptive control impulsive control generalized Barbalat's lemma.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

MODEL ANALYSIS AND PARAMETER EXTRACTION FOR MOS CAPACITOR INCLUDING QUANTUM MECHANICAL EFFECTS

引用

Journal of Computational Mathematics 2006年第3期24卷 401-411页

作者： hai-yan jiang Ping-wen Zhang LMAM CCSE and School of Mathematical Sciences.Peking University Beijing 100871 China

The high frequency CV curves of MOS capacitor have been studied. It is shown that semiclassical model is a good approximation to quantum model and approaches to classical model when the oxide layer is thick. This conclusion provides us an efficient （semiclassical） model including quantum mechanical effects to do parameter extraction for ultrathin oxide device. Here the effective extracting strategy is designed and numerical experiments demonstrate the validity of the strategy.

关键词： Poisson Equation SchrSdinger Equation MOS Capacitor Quantum Effect,Sensitivity Parameter Extraction.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Study of ion temperature gradient driven instability from reduced Braginskii equations

引用

核聚变与等离子体物理 2006年第4期26卷 268-271页

作者： jiang hai-bin WANG Ai-ke Southwestern Institute of Physics Chengdu 610041

A new dispersion relation for the ion temperature gradient(ITG) driven instability in toroidal plasma is derived from the reduced Braginskii *** includes the effects of both the safety factor q and the adiabatic electron temperature gradient η e =d(lnTe)/d(lnn).The present model reproduces the basic properties of ITG instability obtained by previous *** the other hand,it is found numerically that the safety factor q enhances the ITG instabilities while the quantity η e reduces them.

关键词： ITG instability Safety factor Branginskii equations

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in the Application of Molecular Diagnostic Techniques to Brucellosis

引用

Biomedical and Environmental Sciences 2024年第7期37卷 790-794页

作者： haiwen Liu hai jiang School of Public Health Baotou Medical CollegeBaotou 014040Inner Mongolia AutonomousChina National Key Laboratory of Intelligent Tracing and Forecasting for Infectious Diseases National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Brucellosis is a zoonotic infectious and allergic disease caused by Brucella *** occurs worldwide and has had a huge economic impact on the livestock industry in many countries and *** has become a major public health *** is an endoparasitic,non-motile Gram-negative bacterium capable of surviving within a diverse range of domestic animal hosts.

关键词： problem diverse capable

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Weathering geochemistry and palaeoclimate implication of the Early Permian mudstones from eastern Henan Province, North China

引用

Journal of Palaeogeography 2017年第4期6卷 370-380页

作者： jiang-hai Yang Yuan-Sheng Du State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences

Terrigenous clastic sediments are generated by the integration of the Earth surface processes and their deep-time counterparts provide a valuable archive for regional/global climatic, geographic and landscape evolution. It is thus important to read and interpret these deep-time sedimentary records, especially for reconstructing continent climate. Previous studies on the Early Permian sequences from the North China document a dominant control of source chemical weathering on mudstone compositions and its linkage with continent climate conditions. Based on the weathering geochemical data of these mudstones, element mobility during weathering can be ordered as Ca 〉 Na ≥ Mg 〉 Sr 〉 K ≥ Ba 〉 Rb. The weathering regime in the source area is inferred to be supply-limited according to the estimated continent physical erosion rate and regional tectonic evolution, sedimentation in North China. Further exploration of palaeoclimate implication is presented in terms of variation of high-to-low latitudinal temperature gradient across the Early Permian glacial to post-glacial climate transition.

关键词： Chemical weathering Weathering geochemistry Mudstones Early Permian North China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Timing and Source of the Hermyingyi W-Sn Deposit in Southern Myanmar, SE Asia: Evidence from Molybdenite Re-Os Age and Sulfur Isotopic Composition

引用

Journal of Earth Science 2019年第1期30卷 70-79页

作者： hai jiang Shao-Yong jiang Wenqian Li Kuidong Zhao State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Faculty of Earth Resources Collaborative Innovation Center for Exploration of Strategic Mineral Resources China University of Geosciences Key Laboratory of Mineralogy and Metallogeny Guangzhou Institute of Geochemistry Chinese Academy of Sciences

The Hermyingyi W-Sn deposit, situated in southern Myanmar, SE Asia, is a typical quartz-vein type W-Sn deposit. The ore-bearing quartz veins are mainly hosted by the Hermyingyi monzogranite which intruded into the Carboniferous metasedimentary rocks of Mergui Series. According to mineral assemblages and crosscutting relationships, four ore-forming stages are recognized:(1) silicate-oxide stage;(2) quartz-sulfide stage;(3) barren quartz vein stage;(4) supergene stage. Five molybdenite samples from the deposit yield Re-Os model ages ranging from 67.8±1.6 to 69.2±1.6 Ma(weighted mean age of 68.7±1.2 Ma), and a well-defined isochron age of 68.4±2.5 Ma(MSWD=0.18, 2σ). This Re-Os age is consistent with the previously published zircon U-Pb age of the Hermyingyi monzogranite(70.0±0.4 Ma)(MSWD=0.9, 2σ) within errors, which indicates a genetic link between the monzogranitic magmatism and W-Sn mineralization. The new high-precision geochronological data reveal that the granitic magmatism and associated W-Sn mineralization in southern Myanmar took place during the Late Cretaceous(70–68 Ma). The extremely low Re contents(22.9 ppb to 299 ppb) in molybdenite, coupled with sulfide δ^(34)S values in the range of +1.9‰ to +5.6‰ suggest that ore-forming metals were predominately sourced from the crustal-derived granitic magma.

关键词： Hermyingyi W-Sn deposit molybdenite Re-Os dating sulfur isotopes Myanmar SE Asia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：