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Transparent micropatterned conductive films based on highlyordered nanowire network

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Nano Research 2024年第5期17卷 4288-4297页

作者： Xin-Ran Zhang hai-Tao deng Xu Zeng Yi-Lin Wang Peng Huang Xiao-Sheng Zhang School of Integrated Circuit Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Transparent conductive films that are based on nanowire networks are essential to construct flexible,wearable,and even stretchable ***,large-scale precise micropatterning,especially with regard to the controllability of the organizing orientation of nanowires,is a critical ***,we proposed a liquid film rupture self-assembly approach for manufacturing transparent conductive films with microstructure arrays based on a highly ordered nanowire *** large-scale microstructure conductive films were fabricated through air-liquid interface self-assembly and liquid film rupture *** typical micropattern morphologies,including square,hexagon,circle,serpentine,etc.,were prepared to reveal the universal applicability of the proposed *** homogeneity and controllability of this approach were verified for multiple *** the assembly cycles increasing,the optical transmittance decreases *** addition,theoretical model analysis is carried out,and the analytical formula of the speed of the film moving with the surface tension and the density of the liquid film is ***,the feasibility of this approach for piezoresistive strain sensors is *** fabrication approach demonstrated a cost-effective and efficient method for precisely arranging nanowires,which is useful in transparent and wearable applications.

关键词： flexible electronics transparent conductive network micropatterning nanowires micro electromechanical systems(MEMS)

Ferroptosis inhibitors reduce celastrol toxicity and preserve its insulin sensitizing effects in insulin resistant HepG2 cells

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Journal of Integrative Medicine 2024年第3期22卷 286-294页

作者： Jia-jia Liu Xue Zhang Bang-lan Cai Man-man Qi Yong-bin Chi Bin Peng deng-hai Zhang School of Medicine Shanghai UniversityShanghai 200444China Shanghai Health Commission Key Lab of Artificial Intelligence-Based Management of Inflammation and Chronic Diseases Shanghai Pudong Gongli HospitalSecondary Military Medical UniversityShanghai 200135China School of Basic Medicine Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina

Objective:Research has shown that celastrol can effectively treat a variety of diseases,yet when passing a certain dosage threshold,celastrol becomes toxic,causing complications such as liver and kidney damage and erythrocytopenia,among *** this dichotomy in mind,it is extremely important to find ways to preserve celastrol’s efficacy while reducing or preventing its ***:In this study,insulin-resistant Hep G2(IR-Hep G2)cells were prepared using palmitic acid and used for in vitro ***-Hep G2 cells were treated with celastrol alone or in combination with Nacetylcysteine(NAC)or ferrostatin-1(Fer-1)for 12,24 or 48 h,at a range of *** counting kit-8assay,Western blotting,quantitative reverse transcription-polymerase chain reaction,glucose consumption assessment,and flow cytometry were performed to measure celastrol’s cytotoxicity and whether the cell death was linked to ***:Celastrol treatment increased lipid oxidation and decreased expression of anti-ferroptosis proteins in IR-Hep G2 *** downregulated glutathione peroxidase 4(GPX4)m *** docking models predicted that solute carrier family 7 member 11(SLC7A11)and GPX4 were covalently bound by ***,we found for the first time that the application of ferroptosis inhibitors(especially NAC)was able to reduce celastrol’s toxicity while preserving its ability to improve insulin sensitivity in IR-Hep G2 ***:One potential mechanism of celastrol’s cytotoxicity is the induction of ferroptosis,which can be alleviated by treatment with ferroptosis *** findings provide a new strategy to block celastrol’s toxicity while preserving its therapeutic effects.

关键词： Celastrol Insulin resistance Ferroptosis N-Acetylcysteine Palmitic acid Molecular docking

Development of a high-repetition-rate lumped-inductance kicker magnet prototype for the beam switchyard of SHINE

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Nuclear Science and Techniques 2024年第2期35卷 20-31页

作者： Yong-Fang Liu Rui-Ping Wang Jin Tong Bo Zhang Si Chen Qi-Bing Yuan hai-Xiao deng Ming Gu Bo Liu Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201412People’s Republic of China

The Shanghai high-repetition-rate X-ray free-electron laser and extreme light facility(SHINE)operates at a maximum repetition rate of 1 *** magnets are key components that distribute electron bunches into three different undulator lines in a bunch-by-bunch *** kicker field width must be less than the time interval between bunches.A lumpedinductance kicker prototype was developed using a vacuum chamber with a single-turn *** full magnetic field strength was 0.005 *** paper presents the requirements,design considerations,design parameters,magnetic field calculations,and measurements of the kicker *** relevant experimental results are also *** pulse width of the magnetic field was approximately 600 ns,and the maximum operation repetition rate was 1 *** developed kicker satisfies the requirements for the SHINE ***,numerous recommendations for the future optimization of kicker magnets are provided.

关键词： X-ray free-electron laser Kicker magnet Beam switchyard High repetition rate Ni-Zn ferrites

Super P and MoO2/MoS2 co-doped gradient nanofiber membrane as multi-functional separator for lithium–sulfur batteries

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Rare Metals 2024年第9期43卷 4263-4273页

作者： Xin Liang Dong-Qing Zhao Qian-Qian Huang Sheng Liang Li-Li Wang Lei Hu Ling-Li Liu Kun-Hong Hu Chong-hai deng Sheng Cheng Er-Tao Zhu Hua-Xia deng School of Energy Materials and Chemical Engineering LIB Technology Center of Anhui ProvinceHefei University Instrumental Analysis Centre Hefei University of Technology Hefei Youngy Energy Materials Co. Ltd. Department of Modern Mechanics University of Science and Technology of China

Lithium-sulfur battery is one of the most promising battery systems for industrialization due to its high theoretical specific capacity and high energy ***,the??shuttle effect??has restrained the advancement of lithium-sulfur *** this work,a gradient-structured nanofiber membrane with pure gelatin on one side and Super P-MoO2/MoS2-gelatin on the other side was created using a multi-step electrostatic spinning technique,which was applied for multi-functional separator for lithium-sulfur *** pure gelatin layer facing the anode side primarily homogenizes the lithium flux,whereas the Super P-MoO2/MoS2-gelatin layer facing the cathode side primarily adsorbs polysulfides by physical and chemical adsorption and enhancing polysulfide conversion *** findings demonstrate that even after 150 cycles at 0.2C,the lithium-sulfur battery can still sustain a discharge-specific capacity of 572.3 mAh·*** used with Li||Li symmetric batteries,it has a cycle life of more than 1200 *** commercialization of lithium-sulfur batteries is given a fresh idea by this straightforward preparation technique.

关键词： Li–S battery Membrane MoO2/MoS2 Nanofiber

Unraveling the efficacy network: A network meta-analysis of adjuvant external beam radiation therapy methods after hepatectomy

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 205-214页

作者： Gao-Yuan Yang Zhi-Wei He Yong-Chang Tang Feng Yuan Ming-Bo Cao Yu-Peng Ren Yu-Xuan Li Xiao-Rui Su Zhi-Cheng Yao Mei-hai deng Department of Hepatobiliary Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of General Surgery Qilu HospitalShandong UniversityJinan 250012Shandong ProvinceChina Department of General Surgery The First Affiliated HospitalGuangzhou Medical UniversityGuangzhou 511436Guangdong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Primary liver cancer is a malignant tumor with a high recurrence rate that significantly affects patient *** adjuvant external radiation therapy(RT)has been shown to effectively prevent recurrence after liver cancer ***,there are multiple RT techniques available,and the differ-ential effects of these techniques in preventing postoperative liver cancer re-currence require further *** To assess the advantages and disadvantages of various adjuvant external RT methods after liver resection based on overall survival(OS)and disease-free survival(DFS)and to determine the optimal *** This study involved network meta-analyses and followed the PRISMA *** data of qualified studies published before July 10,2023,were collected from PubMed,Embase,the Web of Science,and the Cochrane *** included relevant studies on postoperative external beam RT after liver resection that had OS and DFS as the primary *** magnitudes of the effects were determined using risk ratios with 95%confidential *** results were analyzed using R software and STATA *** A total of 12 studies,including 1265 patients with hepatocellular carcinoma(HCC)after liver resection,were included in this *** was no significant heterogeneity in the direct paired comparisons,and there were no significant differences in the inclusion or exclusion criteria,intervention measures,or outcome indicators,meeting the assumptions of heterogeneity and *** analysis revealed that patients who underwent stereotactic body radiotherapy(SBRT)after resection had longer OS than those who underwent intensity modulated radiotherapy(IMRT)or 3-dimensional conformal RT(3D-CRT).DFS analysis revealed that patients who underwent 3D-CRT after resection had the longest *** who underwent IMRT after resection had longer OS than those who underwent 3D-CRT and longer DFS than those who underwent ***

关键词： Primary liver cancer Hepatocellular carcinoma Network meta-analysis External beam radiation therapy Stereotactic body radiotherapy Intensity modulated radiotherapy

基于黑山南北高速公路的东欧公路机电工程施工风险研究

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公路 2024年第2期69卷 181-184页

作者：高阳邓海峰中国公路工程咨询集团有限公司北京市100089 中咨泰克交通工程集团有限公司北京市100083 中国路桥工程有限责任公司北京市100011

黑山南北高速公路机电工程施工线路较长,子系统众多,且施工区域情况复杂,通过对项目桥隧构造物、机电工程主设计和施工方案,并结合项目所处环境、机电工程本身施工特点进行风险研究,主要梳理出自然、交通安全、偷盗、交叉作业和预留预... 详细信息

黑山南北高速公路机电工程施工线路较长,子系统众多,且施工区域情况复杂,通过对项目桥隧构造物、机电工程主设计和施工方案,并结合项目所处环境、机电工程本身施工特点进行风险研究,主要梳理出自然、交通安全、偷盗、交叉作业和预留预埋等通用风险,以及与机电工程相关的高处坠落、触电事故、物体打击、机械伤害和坍塌事故等“五大伤害”;同时还针对错误施工工艺带来的返工、整改风险,以及特殊设备安装和在莫拉查大桥、隧道等重点区域施工风险进行研究。研究结论除用于指导本工程建设外,还将为今后中国企业在东欧进一步从事公路机电工程建设提供指导依据。

关键词：公路工程机电工程施工风险黑山南北高速公路

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高速列车顶层设计指标分解研究现状与展望

西南交通大学学报 2024年第2期59卷 456-466页

作者：张海柱黎荣丁国富马凯邓海西南交通大学机械工程学院四川成都610031 中车长春轨道客车股份有限公司工程研究中心吉林长春130062

顶层设计指标分解是决定高速列车正向设计周期长短和成功与否的首要环节.首先,在阐述运输能力、安全舒适、绿色环保、经济性等高速列车顶层设计指标的基础上,从系统结构组成、运行边界条件以及大系统耦合作用等角度提出高速列车顶层设... 详细信息

顶层设计指标分解是决定高速列车正向设计周期长短和成功与否的首要环节.首先,在阐述运输能力、安全舒适、绿色环保、经济性等高速列车顶层设计指标的基础上,从系统结构组成、运行边界条件以及大系统耦合作用等角度提出高速列车顶层设计指标分解所面临的技术挑战;然后,论述设计指标分解方法、设计指标分解关联模型和设计指标分解协调策略3个方面研究现状,并分析现有方法的不足与新需求;最后,展望群落生态学在高速列车顶层设计指标分解中的适用性,剖析基于群落生态学的高速列车顶层设计指标分解将会面临的关键问题,并给出相应的解决技术路线,以期为高速列车顶层设计指标分解的深入研究和实践提供参考.

关键词：高速列车设计指标正向设计分解群落生态学

受电弓仿生导流罩对高速列车横风气动特性影响研究

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铁道科学与工程学报 2024年第3期21卷 936-948页

作者：张洁丁艳思邓海韩帅高广军中南大学重载快捷大功率电力机车全国重点实验室湖南长沙410075 中南大学交通运输工程学院轨道交通安全教育部重点实验室湖南长沙410075 轨道交通列车安全保障技术国家地方联合工程研究中心湖南长沙410075 中车长春轨道客车股份有限公司总体研发部吉林长春130062

横风作用下高速列车气动横向力和倾覆力矩显著增加,气动性能显著恶化,列车脱轨、倾覆可能性增大,严重影响列车运行安全。受电弓作为高速列车核心的外突部件,直接受到横风的影响,因此改善受电弓区域的横风气动性能显得尤为重要。以鞘翅... 详细信息

横风作用下高速列车气动横向力和倾覆力矩显著增加,气动性能显著恶化,列车脱轨、倾覆可能性增大,严重影响列车运行安全。受电弓作为高速列车核心的外突部件,直接受到横风的影响,因此改善受电弓区域的横风气动性能显得尤为重要。以鞘翅目生物形态为原型,构建受电弓仿生导流罩几何外形,并以8车编组高速列车为基准,建立4种不同的计算模型:原始模型(模型Ⅰ)、仅受电弓Ⅰ加装导流罩(模型Ⅱ)、仅受电弓Ⅱ加装导流罩(模型Ⅲ)、受电弓Ⅰ和Ⅱ均加装导流罩(模型Ⅳ)。基于三维稳态SST k-ω双方程湍流模型,分析不同方案下高速列车整车以及受电弓区域的横风气动性能。研究结果表明:安装受电弓导流罩后,气流更为平顺地越过受电弓区域,阻滞效应减小,下游车体顶部和受电弓Ⅱ(升弓)区域的气流速度有所增加,同时造成列车背风侧的流场结构改变。相比原始模型(模型Ⅰ),导流罩模型(模型Ⅱ、Ⅲ和Ⅳ)均可减小列车气动横向力和倾覆力矩,其中模型Ⅱ和模型Ⅲ的横向力分别减少9.65%、4.18%,倾覆力矩分别减少11.47%、4.37%;受电弓Ⅰ与受电弓Ⅱ均被包裹的模型Ⅳ效果最为显著,8车编组列车横向力和倾覆力矩分别减少11.39、16.81%。研究成果可为横风环境下新一代高速列车受电弓区域优化设计提供参考。

关键词：高速受电弓仿生导流罩横风适应性速度分布

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外置转向架包覆对高速列车气动阻力影响

铁道科学与工程学报 2024年第1期21卷 26-37页

作者：邓海丁艳思向南燊项涛张洁梁习锋中南大学交通运输工程学院轨道交通安全教育部重点实验室湖南长沙410075 轨道交通列车安全保障技术国家地方联合工程研究中心湖南长沙410075 中车长春轨道客车股份有限公司总体研发部吉林长春130062

转向架作为高速列车大面积裸露在外且外形复杂的运行部件受到列车底部气流的直接作用,区域气动外形结构对高速列车整车气动阻力具有重要影响。基于三维稳态SST k-ω双方程湍流模型,采用数值仿真方法研究了轴箱外置式转向架不同包覆方式... 详细信息

转向架作为高速列车大面积裸露在外且外形复杂的运行部件受到列车底部气流的直接作用,区域气动外形结构对高速列车整车气动阻力具有重要影响。基于三维稳态SST k-ω双方程湍流模型,采用数值仿真方法研究了轴箱外置式转向架不同包覆方式对高速列车气动性能的影响。研究了转向架区域安装小裙板、半包裙板、全包裙板、全包裙板+小底板以及全包裙板+大底板等5种方案下的高速列车气动性能,比较了不同方案下高速列车气动阻力的变化规律,阐明了高速转向架包覆方式对整车气动阻力、车底流动特性以及列车表面压力分布的影响。研究结果表明:随着转向架裙板包覆面积的增加,转向架腔后端板受到的气流冲击逐渐减弱,后端板上的正压分布降低,列车转向架区域周围的边界层厚度逐渐减小,转向架区域内的压力分布差异性逐渐减小,从而实现了列车整车气动阻力系数的降低。与小裙板模型相比,半包裙板、全包裙板、全包裙板+小底板以及全包裙板+大底板模型的列车气动阻力系数分别降低了5.2%、8.65%、10.3%、11.1%。对于轴箱外置式转向架来说,全包裙板+大底板方案可有效改善转向架区域流场,降低整车气动阻力。研究得到的转向架包覆方式将为新一代高速列车气动减阻设计提供有利支撑,实现列车气动节能。

关键词：轴箱外置式转向架高速列车包覆方式气动减阻流场结构