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Diet of patients after pouch surgery may affect pouch inflammation

World Journal of Gastroenterology 2013年第38期19卷 6458-6464页

作者： Orit Ianco hagit tulchinsky Michal Lusthaus Amos Ofer Erwin Santo Nachum Vaisman Iris Dotan Comprehensive Pouch Clinic IBD CenterDepartment of Gastroenterology and Liver DiseasesTel Aviv Sourasky Medical CenterTel Aviv 64239Israel Sackler Faculty of Medicine Tel Aviv UniversityTel Aviv 64239Israel Comprehensive Pouch Clinic and the Proctology Unit Department of SurgeryTel Aviv Sourasky Medical CenterTel Aviv 64239Israel Unit of Clinical Nutrition Tel Aviv Sourasky Medical CenterTel Aviv 64239Israel

AIM:To investigate the diet of pouch patients compared to healthy controls,and to correlate pouch patients’diet with disease ***:Pouch patients were recruited and prospectively followed-up at the Comprehensive Pouch Clinic at the Tel Aviv Sourasky Medical *** behavior was determined based on clinical,endoscopic and histological *** age-and sex-matched volunteers were selected from the"MABAT"Israeli Nutrition and Public Health Governmental Study and served as the control *** the participants completed a 106-item food frequency questionnaire categorized into food groups and nutritional values based on those used in the United States Department of Agriculture food pyramid and the Israeli food *** on Dietary behavior,food avoidance,the use of nutritional supplements,physical activity,smoking habits,and body-mass index(BMI)were also *** patients who had familial adenomatous polyposis(n=3),irritable pouch syndrome(n=4),or patients whose pouch surgery took place less than one year previously(n=5)were excluded from ***:The pouch patients(n=80)consumed significantly more from the bakery products food group(1.2±1.4 servings/d vs 0.6±1.1 servings/d,P<0.05)and as twice as many servings from the oils and fats(4.8±3.4 servings/d vs 2.4±2 servings/d,P<0.05),and the nuts and seeds food group(0.3±0.6 servings/d vs 0.1±0.4 servings/d,P<0.05)compared to the controls(n=80).The pouch patients consumed significantly more total fat(97.6±40.5 g/d vs 84.4±39 g/d,P<0.05)and fat components[monounsaturated fatty acids(38.4±16.4 g/d vs 30±14 g/d,P<0.001),and saturated fatty acids(30±15.5 g/d vs 28±14.1 g/d,P<0.00)]than the *** contrast,the pouch patients consumed significantly fewer carbohydrates(305.5±141.4 g/d vs 369±215.2 g/d,P=0.03),sugars(124±76.2 g/d vs 157.5±90.4 g/d,P=0.01),theobromine(77.8±100 mg/d vs 236.6±244.5 mg/d,P<0.00),retinol(474.4±337.1μg/d vs 832.4±609.6μg/d,P<0.001)and dietary fibers(26.2±15.4

关键词： Ulcerative colitis Dietary reference intake Body mass index Ileal-pouch anal anastomosis Pouch surgery Food frequency questionnaire

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Incidence and management of colonoscopic perforations: 8 years' experience

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World Journal of Gastroenterology 2006年第26期12卷 4211-4213页

作者： hagit tulchinsky Osnat Madhala-Givon Nir Wasserberg Shiomo Lelcuk Yaron Niv Department of Surgery B Rabin Medical CenterBeilinson CampusPetah Tiqvaand Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Department of Gastroenterology Rabin Medical Center Beilinson CampusPetah Tiqvaand Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael

AIM： To review the experience of a major medical teaching center with diagnostic and therapeutic colonoscopies and to assess the incidence and management of related colonic perforations. METHODS： All colonoscopies performed between January 1994 and December 2001 were studied. Data on patients, colonoscopic reports and procedure-related complications were collected from the departmental computerized database. The medical records of the patients with post procedural colonic perforation were reviewed. RESULTS： A total of 12 067 colonoscopies were performed during the 8 years of the study. Seven colonoscopic perforations （4 females, 3 males） were diagnosed （0.058%）. Five occurred during diagnostic and two during therapeutic colonoscopy. Six were suspected during or immediately after colonoscopy. All except one had signs of diffuse tenderness and underwent immediate operation with primary repair done in 4 patients. No deaths were reported. CONCLUSION： Perforation rate during colonoscopy is low. Nevertheless, it is a serious complication and its early recognition and treatment are essential to optimize outcome. In patients with diffuse peritonitis early operative intervention makes primary repair a safe option.

关键词： Colonoscopy Complications Perforation Polypectomy Management

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Vitamin K supplementation to prevent hemorrhagic morbidity and mortality of newborns in India and China

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World Journal of Pediatrics 2017年第1期13卷 15-19页

作者： Rajesh Kumar Rai Jing Luo Theodore Herzl tulchinsky Society for Health and Demographic Surveillance SuriBirbhumWest BengalIndia Braun School Public Health and Community Medicine Hebrew University-HadassahEin KaremJerusalemIsrael

Background?Vitamin K deficiencY bleeding(VKOBl can cause prolonged and bleeding(intracranial hemorrhage)ameng *** can be life—threatening or lead to long-term *** aim of this review article is to reiterate empirical evidence to support the argument that vitamin K should be mandatory for newborns in India and China,as well as in other countries with a high burden of neonatal deaths.

关键词： global health hemorrhagic disease of the newborn intracranial hemorrhage neonatal mortality vitamin K deficiency bleeding disorder

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应用生化指标处理高危产妇

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国际妇产科学杂志 1982年第4期 229-232页

作者： tulchinsky D

由于对控制胎盘激素的合成与代谢知识的日渐增进,应用雌激素测定来估价妊娠情况有了进一步的认识。然而,若不全面估价,则在探索及处理高危妊娠时会反复出现各种问题。一、E;激素测定法的估价由于胎儿死亡前常见雌三醇（E;）水平降低（超... 详细信息

由于对控制胎盘激素的合成与代谢知识的日渐增进,应用雌激素测定来估价妊娠情况有了进一步的认识。然而,若不全面估价,则在探索及处理高危妊娠时会反复出现各种问题。一、E;激素测定法的估价由于胎儿死亡前常见雌三醇（E;）水平降低（超过50%）或长期低于正常水平,及早处理或分娩可避免很多胎儿死亡。因而应用E;测定法可作为估价胎儿健康状态的一辅助方法,可降低宫内胎儿死亡的发生率。但因E;测定仅是许多预测胎儿健康状态方法之一,故对胎儿死亡率减少的真正价值则难予

关键词：胎儿肝脏激素测定估价催乳素促乳素胎盘功能 DHEAS 宫内生长迟缓高危妊娠胎儿窘迫宫内窘迫胎儿疾病

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