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Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality

World Journal of Clinical Cases 2021年第29期9卷 8749-8762页

作者： Diana Ronderos Alaa Mabrouk Salem Omar hafsa abbas Jasbir Makker Ahmed Baiomi Haozhe Sun Nikhitha Mantri Yongsun Choi Ked Fortuzi Dongmin Shin Harish Patel Sridhar Chilimuri Department of Internal Medicine BronxCare Hospital CenterBronxNY 10457United States Department of Cardiology Mount Sinai Morning SideNew YorkNY 10023United States Division of Gastroenterology Department of MedicineBronxCare Health SystemBronxNY 10457United States

BACKGROUND There is little evidence about the association of pre-existing hepatitis C infection(HCV)with outcomes in patients with coronavirus disease 2019(COVID-19).AIM To assess the prevalence of history of HCV among patients with COVID-19 and to study the relationship of in-hospital mortality in relation with other predictors of poor outcomes in the presence or absence of COVID-19 induced acute liver *** In a retrospective single-center study design,1193 patients with COVID-19 infection were *** were then classified into those with and without a history of HCV,50(4.1%)and 1157(95.9%)*** Multivariate cox-regression models showed that age,HCV,D-Dimer,and ferritin were the only predictors of in-hospital *** liver injury and fibrosis score(Fib-4 score)were not different between both *** coxregression model for liver profile revealed that aspartate aminotransferase/alanine aminotransferase ratio,Fib-4 score,and HCV were predictors of inhospital *** propensity score matching HCV was the only predictor of mortality in the multivariate cox-regression model.A model including HCV was found to add predictive value to clinical and laboratory *** In patients with COVID-19,history of HCV infection leads to an accentuated severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virulence,irrespective of baseline comorbidities,admission laboratory variables,or COVID-19-induced liver injury,which may be related to extrahepatic effects of HCV leading to enhanced ACE-2/TMPRSS mechanisms of SARS-CoV-2 viral entry,baseline cytokine-mediated pro-inflammation,and endothelial dysfunction.

关键词： Hepatitis C Acute liver injury Seropositive COVID-19 Mortality

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Chemical colitis caused by hydrogen peroxide vaginal douche: A case report

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World Journal of Gastrointestinal Endoscopy 2019年第9期11卷 486-490页

作者： Ahmed Baiomi Harish Patel hafsa abbas Vamshidhar Vootla Jasbir Makker Department of Medicine Division of GastroenterologyBronx Care Health System1650 Selwyn AveBronxNY 10457United States Western Maryland Health System 12500 Willowbrook RdCumberlandMD 21502United States

BACKGROUND Hydrogen peroxide is one of the most common household disinfectants *** peroxide has been documented as a rare cause of chemical *** SUMMARY We present a case of 31 years old lady who presented to our hospital with rectal bleeding and abdominal pain after using hydrogen peroxide vaginal douche as an *** underwent colonoscopy which showed findings suggestive of chemical colitis and was managed *** peroxide can induce chemical injury in the *** presentation and endoscopic findings of chemical colitis are *** taking is an important tool in identifying the underlying *** of literature showed few case reports,mostly were managed with oral antibiotics and conservative *** Chemical colitis is usually managed *** including perforation,stricture and peritonitis may happen and need aggressive treatment accordingly.

关键词： Chemical colitis Hydrogen peroxide Colitis Vaginal douche Colonoscopy Case report

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Biosynthesis of Flower-Shaped CuO Nanostructures and Their Photocatalytic and Antibacterial Activities

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Nano-Micro Letters 2020年第2期12卷 224-234页

作者： hafsa Siddiqui MSQureshi Fozia Zia Haque Department of Physics Sha-Shib College of Science and ManagementBhopal 462030India Optical Nanomaterial Lab Department of PhysicsMaulana Azad National Institute of TechnologyBhopal 462003India

Copper oxide nanoflowers(CuO-NFs)have been synthesized through a novel green route using Tulsi leaves-extracted eugenol(4-allyl-2-methoxyphenol)as reducing *** results reveal the growth of crystalline singlephase CuO-NFs with monoclinic *** prepared CuO-NFs can effectively degrade methylene blue with 90%*** also show strong barrier against ***(27±2 mm)at the concentration of 100μg mL−1,while at the concentration of 25μg mL−1 weak barrier has been found against all examined bacterial *** results provide important evidence that CuO-NFs have sustainable performance in methylene blue degradation as well as bacterial organisms.

关键词： Copper oxide O.Sanctum Eugenol Biosynthesis Photocatalysis Antibacterial

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Energy Optimised Security against Wormhole Attack in IoT-Based Wireless Sensor Networks

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Computers, Materials & Continua 2021年第8期68卷 1967-1981页

作者： hafsa Shahid Humaira Ashraf hafsa Javed Mamoona Humayun Nz Jhanjhi Mohammed A.AlZain Department of Computer Science and Software Engineering International Islamic University IslamabadIslamabadPakistan Department of Information Systems College of Computer and Information ScienceJouf UniversityAl-JoufSaudi Arabia School of Computer Science and Engineering(SCE) Taylor’s UniversitySelangorMalaysia Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

An IoT-based wireless sensor network(WSN)comprises many small sensors to collect the data and share it with the central *** sensors are battery-driven and resource-restrained devices that consume most of the energy in sensing or collecting the data and transmitting *** data sharing,security is an important concern in such networks as they are prone to many threats,of which the deadliest is the wormhole *** attacks are launched without acquiring the vital information of the network and they highly compromise the communication,security,and performance of the *** the IoT-based network environment,its mitigation becomes more challenging because of the low resource availability in the sensing *** have performed an extensive literature study of the existing techniques against the wormhole attack and categorised them according to their *** analysis of literature has motivated our *** this paper,we developed the ESWI technique for detecting the wormhole attack while improving the performance and *** algorithm has been designed to be simple and less complicated to avoid the overheads and the drainage of energy in its *** simulation results of our technique show competitive results for the detection rate and packet delivery *** also gives an increased throughput,a decreased end-to-end delay,and a much-reduced consumption of energy.

关键词： IoT Internet of Things energy wormhole WSN wireless sensor networks

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Spectrum of venous thromboembolism in adult patients with ulcerative colitis in Pakistan:A single center retrospective study

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World Journal of Clinical Cases 2025年第6期13卷 9-13页

作者： Masood Muhammad Karim hafsa Shaikh Faisal Wasim Ismail Department of Medicine The Aga Khan University HospitalKarachi 74800Pakistan Department of General Surgery The Aga Khan University HospitalKarachi 74800Pakistan

BACKGROUND Patients with inflammatory bowel disease are at a 2-8-fold higher risk of deve-loping venous thromboembolism(VTE)as compared to the general *** the exact pathogenesis is unclear,the literature suggests that increased risk of thromboembolic events in such patients occurs as a result of increased coagulation factors,inflammatory cytokines,and reduction in anticoagulants leading to a prothrombotic *** To assess the prevalence,risk factors,management,and outcome of ulcerative colitis(UC)patients who develop *** This was a retrospective chart review done in The Gastroenterology Department of The Aga Khan University *** was collected from medical records for all patients admitted with a diagnosis of UC from January 2012 to December *** Seventy-four patients fulfilled the inclusion *** mean±SD of age at presentation of all UC patients was 45 years±10 years whereas for those who developed VTE,it was 47.6 years±14.7 *** and diabetes were the most common co-morbid seen among UC patients with a frequency of 17(22.9%)and 12(16.2%),respectively.A total of 5(6.7%)patients developed *** venous thrombosis was the most common thromboembolic phenomenon seen in 3(60%)*** the patients with UC and concomitant VTE were discharged home(5;100%).CONCLUSION The prevalence of VTE with UC in Pakistani patients corresponds with the international ***,multi-centric studies are required to further explore these results.

关键词： Deep venous thrombosis Inflammatory bowel disease Low-middle-income country Anticoagulation Protein C deficiency

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Lithium-Doped CuO Nanosheets:Structural Transformation,Optical,and Electrical Characteristics with Enhanced Photocatalytic and Solar Cell Performance

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Energy & Environmental Materials 2021年第4期4卷 646-657页

作者： hafsa Siddiqui Mohammad Shums Qureshi Fozia Z.Haque Optical Nanomaterial Lab Department of PhysicsMaulana Azad National Institute of TechnologyBhopal 462003India Department of Physics Sha-Shib College of Science and ManagementBhopal 462036India

Energy and environmental stuff are two of the main worries for humanity,and nanoscience plays a key role in providing the *** nanoresearch activities have attracted lot of attention in the current ***,designing the material with enhanced optoelectronic properties remains the foremost *** the present work,the Li doped CuO nanosheets are synthesized by the chemical route and examined in photovoltaics and environmental remediation *** crystallographic and optical study reveals that crystallite size and bandgap decrease with an increase in lithium-doping concentration up to 5 mole%and beyond that a reverse trend is ***,impedance study has shown the significant contribution of lithium-ions to the total capacitance and ***,the photoactivity of Cu_(1-x)Li_(x)O nanosheets(optimum concentration of Cu_(1-x)Li_(x)O NSs(x=0.05))is projected to the degradation of methylene blue(MB)and used to fabricate bulk heterojunction solar cell together with P3HT and PCBM blend,*** ITO/PEDOT:PSS/P3 HT:PC_(70)BM:Cu_(1-x)Li_(x)O(x=0.05)/Li F/Al solar cell realized higher power-conversion efficiencyη~3.91 than their corresponding pristine deviceη~2.98 with enhanced photocurrent density from 9.026 to 11.56 m A cm^(-2).The proliferation in photocatalysts and solar cells efficiency of Cu_(1-x)Li_(x)O(x=0.05)is mainly attributed to the higher light absorption and lesser electron-hole *** approach for the synthesis of Cu_(1-x)Li_(x)O NSs as potential donor material and device prototypes fabricated is completely safe and cost-effective.

关键词： current density efficiency nanostructures photocatalysts solar cells

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Kinetic Instability of Anisotropic Drift Wave Accompanied by Field Aligned Currents in Solar Coronal Loop

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Communications in Theoretical Physics 2018年第10期70卷 470-476页

作者： hafsa Naim Ch.Uzma G.Murtaza Salam Chair Department of Physics GC University

Solar coronal loops are frequently accompanied by the field-aligned currents, which drive instabilities if the drift velocity u0 > v A the Alfv′en velocity. For our choice of parameters, the critical threshold value of u0/v A is ～ 3.0 for growth and the corresponding current filling factor ～ 10-3-10-4. Below this value we are no longer in the kinetic *** coronal loops also have short-scale density gradients within each loop. The electron resonance in the presence of density gradient causes the drift mode to grow. We study the effect of these two free energy sources, the electron drift and the density gradient, in the presence of temperature anisotropy T⊥_α > T∥_α. These effects simultaneously exist in the coronae. Using gyrokinetic theory, we investigate the influence of these effects, examine how they interplay with each other and study the consequent growth of the magnetosonic wave. We observe that kinetic instability driven by density gradient can be suppressed by field-aligned currents. The temperature anisotropy with chosen signatures causes further stabilizing effect. The results may prove useful to study the heating mechanism of solar coronal loops, acceleration of particles and confinement of particles in the thermonuclear reactors.

关键词： solar corona coronal loops temperature anisotropy density inhomogeneity field-aligned currents gyrokinetic

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Incense smoke(IS)inhalation exposure system:Physicochemical characterization,IS particle deposition and clearance in human airway using MPPD model

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Particuology 2024年第4期87卷 271-285页

作者： Vyas Kumar hafsa Hashmi Anshita Nasreen Ghazi Ansari Jyotsna Singh Inhalation Toxicology Facility Regulatory Toxicology GroupCSR-Indian Institute of Toxicology ResearchLucknow22001UPIndi Academy of Scientific and Innovative Research(AcsSIR) Ghaziabad201002UPIndia Analytical Chemistry Regulatory Toxicology GroupCSIR-Indian Institute of Toxicology ResearchLucknow226001UPIndia

Incense smoke(IS)is source of indoor air pollution and key risk for diverse human *** in-formation is available regarding controlled IS rodent inhalation exposure system and IS particulate matter(PM)deposition in human *** aimed to demonstrate stable ISPM physicochemical parameters of 10 incense products inside the customized whole body inhalation exposure chamber(without animal)connected to smoke generation unit via aerosol mixing *** analyzed for size segregated PM emission,ISPM in vitro aerodynamics(MMAD and GSD determination),fine and ultrafine particle's SEM,SEM-EDX and PAH *** real life exposure scenario by utilizing MMAD,GSD and PM concentration after Tier 1 exposure assessment as key input parameters,ISPM dosimetry in infant(3 months)and adult(21 years male and female)human airways was calculated using multiple-path particle dosimetry(MPPD 3.04)*** median aerodynamic diameter(MMAD)and geo-metric standard deviation(GSD)ranged between 0.55 and 2.10μm and 1.22 to 1.77(polydisperse)***1.0 and PM0.1 showed multiple morphology and presence of heavy and trace *** like acenaphthylene,anthracene,fluorene,naphthalene and phenanthrene were detected(0.84-143.17μg/g).MPPD results showed higher ISPM deposition in pulmonary region and lowest in trachea bronchial *** deposition in tissue was higher in lower,peripheral lung as compared to upper and central lung *** body inhalation exposure system showed stable IS atmosphere(physi-cochemical parameters)indicating the device suitability in future inhalation *** ISPM deposition fraction and clearance data showed deep lung penetrating and retention behavior with higher risk in infant followed by female and then *** modeled particle deposition and clearance data may be useful in risk assessment analysis of IS.

关键词： Inhalation Incense smoke Multiple-path particle dosimetry(MPPD) Particle deposition Particulate matter(PM) Mass median aerodynamic diameter (MMAD) Human airway

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Study of Fractional Order Dynamical System of Viral Infection Disease under Piecewise Derivative

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Computer Modeling in Engineering & Sciences 2023年第7期136卷 921-941页

作者： Kamal Shah hafsa Naz Thabet Abdeljawad Bahaaeldin Abdalla Department of Mathematics and Sciences Prince Sultan UniversityP.O.Box 66833Riyadh11586Saudi Arabia Department of Mathematics University of MalakandChakdara Dir(L)Khyber Pakhtunkhwa18000Pakistan Department of Medical Research China Medical UniversityTaichung40402Taiwan

This research aims to understand the fractional order dynamics of the deadly Nipah virus(NiV)*** focus on using piecewise derivatives in the context of classical and singular kernels of power operators in the Caputo sense to investigate the crossover behavior of the considered dynamical *** establish some qualitative results about the existence and uniqueness of the solution to the proposed *** utilizing the Newtonian polynomials interpolation technique,we recall a powerful algorithm to interpret the numerical findings for the aforesaid ***,we remark that the said viral infection is caused by an RNA type virus which can transmit from animals and also from an infected person to *** bats which are also known as flying foxes are one of the sources of transmission of NiV *** in this work,we investigate its transmission mechanism through some new concepts of fractional calculus for further analysis and *** present the approximate results for different compartments using different fractional *** using the piecewise derivative concept,we detect the crossover ormulti-steps behavior in the transmission dynamics of the mentioned ***,the considered form of the derivative is used to deal with problems exhibiting crossover behaviors.

关键词： NiV disease fractional calculus piecewise derivative qualitative results newton polynomial RNA virus

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Optimal integration of battery energy-storage system with high penetration of renewable energy in radial distribution network

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Clean Energy 2022年第3期6卷 404-411页

作者： hafsa Imra Sheikh Mahesh Kumar Rathi Amir Mahmood Soomro Department of Electrical Engineering Mehran University of Engineering and TechnologyJamshoroPakistan

Considering the intermittent nature of renewable energy,a storage system to reserve power in off-peak hours and then to supply it during peak hours is ***,if these storage devices in a network are not placed in an appropriate manner,the advantages can never be *** this study,the allocation and sizing strategies of a battery energy-storage system(BESS)in an optimal way are proposed to improve the performance of the radial distribution *** test network adopted is a standard IEEE 33 bus network that is integrated with solar *** are carried out in DIgSILENT PowerFactory for the distribution network model and the process of optimization is done through MATLAB®.The optimization algorithm adopted is the genetic *** system is studied for 24 hours with a step size of 15 minutes,employing a time-sweep analysis of dynamic *** is studied under three different scenarios and the results are *** results illustrate a considerable reduction in power losses in the case of the optimized *** total losses before the optimization process are 16365.57 *** total losses after the employment of the proposed solution are 10246.5 kW,which means that the losses are reduced by≤62%.

关键词： energy and environment energy storage solar

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