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Disparities in esophageal cancer incidence and esophageal adenocarcinoma mortality in the United States over the last 25-40 years

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World Journal of Gastrointestinal Endoscopy 2023年第12期15卷 715-724页

作者： hafiz muhammad sharjeel arshad Umer Farooq Ayesha Cheema Ayesha arshad Muaaz Masood Kenneth J Vega Division of Gastroenterology&Hepatology Augusta University-Medical College of GeorgiaAugustaGA 30912United States Department of Internal Medicine Loyola Medicine/MacNeil HospitalBerwynIL 60402United States Department of Medicine Fatima Memorial Medical CollegeLahore 54000PunjabPakistan Department of Medicine Augusta University-Medical College of GeorgiaAugustaGA 30912United States

BACKGROUND Esophageal carcinoma presents as 2 types,esophageal adenocarcinoma(EAC)and esophageal squamous cell carcinoma(ESCC)with the frequency of both changing in the United States(US).AIM To investigate EAC/ESCC incidence time trends among the 3 main US racial groups and investigate trends in US EAC survival by *** Twenty-five years(1992-2016)of data from SEER 13 program was analyzed to compare incidence trends in EAC and ESCC between non-Hispanic whites(nHW),non-Hispanic Blacks(nHB)and Hispanics(Hisp)using SEERStat®.In addition,SEER 18 data,from 1975-2015,on EAC in the US was analyzed to evaluate racial disparities in incidence and survival using SEERStat®and Ederer II *** In the 3 major US ethnic groups,age-adjusted incidence of ESCC has declined while EAC has continued to rise from *** note,in Hisp,the EAC incidence rate increased while ESCC decreased from 1992 to 2016,resulting in EAC as the predominant esophageal cancer subtype in this group since 2011,joining ***,although ESCC remains the predominant tumor in nHB,the difference between ESCC and EAC has narrowed dramatically over 25 *** survival probabilities were worse in all minority groups compared to *** Hisp have joined nHW as US ethnic groups more likely to have EAC than *** note,EAC incidence in nHB is increasing at the highest rate *** lower EAC incidence in all minority groups compared to nHW,these populations have decreased survival compared to nHW.

关键词： Esophageal carcinoma Ethnicity Incidence Survival Disparity Race

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Facile Synthesis and Crystal Structures of New Ammonium Sulfonates(CA-DNBS and TEA-TMBS)

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Chinese Journal of Structural Chemistry 2013年第10期32卷 1465-1474页

作者： KHAN Islam Ullah arshad muhammad Nadeem SAHIN Onur MUBASHAR-Ur-REHMAN hafiz MUNIR Ayesha HUMAYUN Saba ASIRI Abdullah M Materials Chemistry Laboratory Department of Chemistry GC UniversityLahore 54000Pakistan Centre of Excellence for Advanced Materials Research(CEAMR) King Abdulaziz University P.O.Box 80203Jeddah 21589Saudi Arabia Chemistry Department Faculty of ScienceKing Abdulaziz University P.O.Box 80203Jeddah 21589Saudi Arabia Scientific and Technological Research Application and Research Center Sinop University57010 SinopTurkey

The title compounds, C12HIoN307SCI （I） and C15H27NO3S （II）, crystallize in the monoclinic system, space group P21/c with a = 7.3995（1）, b = 27.8489（6）, c = 9.8246（2）/, fl = 131.349（1）, V = 1519.82（5） A3, Z = 4, F（000） = 768, Rint = 0.033 and S = 1.03 for I, and in the orthorhombic system, space group Pbca with a = 8.6227（1）, b = 16.1480（4）, c = 23.8774（6）/, V= 3324.67（12） A3, Z = 8, F（000） = 1312, Rint = 0.024 and S = 1.04 for II. We have devised a convenient procedure for the synthesis of fused organic salts resulting from 1：1 proton-transfer, using an amine and a derivative ofbenzenesulfonic acid. The synthesized salts have a number of applications ranging from their consumption as eco-friendly solvents and catalysts in organic syntheses, to being used as efficient precursors for the production of sulfa drugs. Structures of compounds 3-chloroanilinium 2,4-dinitrobenzenesulfonate （CA-DNBS） and triethylaminium 2,4,6-trimethylbenzenesulfonate （TEA-TMBS） were determined by single-crystal X-ray diffraction studies and infrared spectroscopy.

关键词： crystal structure ammonium sulfonates 3-chloroanilinium2,4-dinitrobenzenesulfonate triethylaminium 2,4,6-trimethylbenzenesulfonate ionic liquids

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Genetic Diversity and Correlation Studies for Cotton Leaf Curl Disease (CLCuD), Fiber &Yield Related Attributes in Exotic Lines of <i>Gossypium arboreum</i>L.

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American Journal of Plant Sciences 2017年第3期8卷 615-624页

作者： muhammad Idrees Khan hafiz Abdul Haq Kalim Ullah muhammad arshad Abdul Majid CCRI Multan Multan Pakistan CRS Dera Ismail Khan Dera Ismail Khan Pakistan ICARDA Cotton Project Islamabad Pakistan

Genetic diversity provides the foundation for crop improvement. Genetic variation and associations among Cotton Leaf Curl Disease (CLCuD), fiber and yield related traits were investigated in exotic lines of Gossypium arboreum L. in an experimental field at the Central Cotton Research Institute (CCRI), Multan, Pakistan during the crop season 2011-12. One hundred and nineteen (119) accessions imported from USA through the Pakistan and US “Cotton Productivity Enhancement Program” (CPEP), were evaluated in this study. Various statistical approaches including descriptive statistics, correlation and principal component analysis was performed to evaluate and identify desirable genotypes. Results revealed that seed cotton yield was significantly and positively correlated with boll weight and number of bolls plant-1. Similarly, plant height was also significantly correlated with sympodial branches, lint percentage and micronaire value. Lint percentage showed a highly significant and positive correlation with plant height, sympodial branches and micronaire value. With respect to fiber traits, negative and significant relationships were observed between the micronaire value (MIC) and fiber strength. CLCuD showed no relationship with any of the studied traits, as all the G. arboreum L. lines evaluated were scored resistant to CLCuD. Principal component analysis (PCA) showed that the first four out of 11 components contributed about 65.88% of the total variation having an eigen value greater than 1. Based on PCA, the genotypes GS-4, GS-9, GS-8, GS-55 and GS-50 could be utilized successfully in a future breeding program based on having the highest positive loading factor for staple length (0.135) in PC1 and seed cotton yield (0.625), number of bolls plant-1, boll weight, first sympodial nod, staple length and fiber strength in PC2 respectively.

关键词： Gossypium arboreum Genetic Diversity CLCuD Yield Lint % Age Fiber Strength Principle Component Analysis and Correlation

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The circulation of unique reassortment strains of infectious bursal disease virus in Pakistan

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Journal of Integrative Agriculture 2020年第7期19卷 1867-1875页

作者： Altaf HUSSAIN WU Tian-tian FAN Lin-jin WANG Yu-long Farooq Khalid muhammad JIANG Nan GAO Li LI Kai GAO Yu-long LIU Chang-jun CUI Hong-yu PAN Qing ZHANG Yan-ping Asim ASLAM Khan MUTI-UR-REHMAN muhammad Imran arshad hafiz muhammad ABDULLAH WANG Xiao-mei QI Xiao-le Division of Avian Infectious Diseases State Key Laboratory of Veterinary BiotechnologyHarbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069P.R.China OIE Reference Laboratory for Infectious Bursal Disease Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069P.R.China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease and Zoonoses Yangzhou 225009P.R.China Sub-campus Toba Tek Singh University of Agriculture FaisalabadFaisalabad 38040Pakistan Pathology Department University of Veterinary and Animal SciencesLahore 54660Pakistan Institute of Microbiology University of Agriculture FaisalabadFaisalabad 38040Pakistan Department of Animal Sciences Ohio State UniversityColumbus 43210USA1

Infectious bursal disease(IBD),caused by IBD virus(IBDV),is one of the most devastating and immunosuppressive diseases of the poultry and has been a constraint on the sustainable poultry production around the globe including *** the disease is threatening the poulty industry,the nature of predominant strains of IBDV in Pakistan remained *** this study,an epidemiology survey was conducted in the main chicken-farming regions of *** batch of Pakistan IBDVs genes simultaneously covering both VP1 and VP2 were amplified,sequenced,and *** unique segment-reassortant IBDVs(vv-A/Uniq-B),carrying segmentA from vvIBDV and segment B from one unique ancestor,were identifed as one important type of circulating strains in *** data also discovered the characteristic molecular features of Pakistan IBDVs,which will contribute to scientific vaccine selection and effective prevention of the disease.

关键词： infectious bursal disease virus circulating strains reassortant Pakistan

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Two Hybrids Composed of Polyoxometalate and Porphyrin with Remarkable Third-order Optical Nonlinearities Reflecting the Effect of Polyoxometalates

Two Hybrids Composed of Polyoxometalate and Porphyrin with R...

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中国化学会第八届全国配位化学会议

作者： hafiz muhammad Asif Yunshan Zhou Lijuan Zhang Nusrat Shaheen Di Yang Jiaqi Li Yi Long arshad Iqbal Yanqin Li State Key Laboratory of Chemical Resource Engineering Institute of Science Beijing University of Chemical Technology

Two new porphyrin-polyoxometalate hybrids,namely,[(C H) N]H[{COH NC(CH O) P V WO} CN H]·CH CN 1 bearing two covalent-bonded Wells-Dawson type polyoxometalates(POMs) and[(C H) N)] H[COHNC(CH O) P V WO{CHN}]·CH CN 2 bearing one covalent-bonded POM,have been synthesized and thoroughly characterized by means of elemental analysis,ICP,powder XRD,FT-IR, H(P,V) NMR,MALDI-TOF-MS,*** and cyclic voltammetry *** results demonstrate that while all the compounds show remarkable third-order optical nonlinearities,the hybrids 1 and 2 are superior to their corresponding porphyrin precursors(molecular second hyperpolarizability γ = 8.0×10esu for the precursor 54-N-N(1,3-tetrahydroxy-2-(dihydroxymethyl)propan-4-di-yl)benzdiamide,10,15,triphenyl porphyrin for the hybrid 1,γ = 2.6×10esu for the precursor 54-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)benz-amide,10,15,20-triphenyl porphyrinfor the hybrid 2)and the hybrid 1(γ= 12.9×10esu) is superior to the hybrid 2(γ = 12.2×10esu) reflecting more POM moieties covalent-bonded to the porphyrin moiety exert more significant influence on the third-order optical ***,it is also found that attachment of POMs on the porphyrin results in significant fluorescence quenching(fluorescence intensity is decreased 97%for the hybrid 1 and 80%for the hybrid 2 with respect to that of their corresponding porphyrin precursors).Small energy difference between singlet and triplet excited states make faster the intersystem crossing(ISC) process,and the faster rate of ISC is also favorable to enhance the NLO responses of hybrids 1 and 2 implying facile electron/energy transfer from the porphyrin moiety to the Dawson POM moiety when the hybrids are subjected to laser irradiation,which is thought to be responsible to the superior of the hybrid 1 to hybrid 2 and the superior of the hybrids to their corresponding porphyrin precursors as well.

关键词： porphyrin polyoxometalate hybrids,third order optical nonlinearity

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Impact of Climate Change on Epidemiology of Various Pests of Wheat Crop in Punjab Pakistan

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American Journal of Plant Sciences 2019年第1期10卷 236-247页

作者： Israr arshad Amer Rasul Syed Ismat Hussain hafiz muhammad Usman Aslam Khizar Hayat Malik Najam Ul Hassan Sidra Muqeet Amina Yasir Umar Shabab Nasir Anum Tehseen Directorate of Pest Warning & Quality Control of Pesticides Punjab Pakistan Department of Plant Pathology University of Agriculture Faisalabad Pakistan Department of Plant Pathology and Microbiology Iowa State University USA Horticultural Research Institute Ayub Agricultural Research Institute (AARI) Faisalabad Pakistan Department of Zoology Government College University Faisalabad Faisalabad Pakistan Institute of Agriculture & Resource Economics University of Agriculture Faisalabad Pakistan

Wheat [Triticum aestivum L. (Poaceae)] is the staple diet of people in Pakistan. It is attacked by many types of pests. Therefore the purpose of this study was to assess the impact of climate change on the ecology and epidemiology of various wheat pests in Punjab, Pakistan. Results indicate that maximum weeds hot spots 242 (5.98%) Phalaris minor, 45 (1.18%) wild oat and 203 (5.01%) broad leaf weeds were noted in 2015. Aphid 31 (0.86%) hot spots were recorded in 2016 while maximum army worm 13 (0.26%) hot spots were noted in 2017. Maximum 70 (1.73%) spots of yellow rust and 85 (2.10%) hot spots of brown rust were observed during 2015 while 84 (4.16%) spots of loose smut were observed during 2017. ANOVA shows that years have no significant difference (P > 0.05) but weeks have significant effect on occurrence of these pest incidences except brown rust. But regression ANOVA was significant (P ≤ 0.05) and regression models equations have been developed on the bases of recorded data. Pest incidence was taken as dependent variable Y and weather factors i.e. minimum temperature as X1, maximum temperature as X2, relative humidity as X3 and rain fall as X4 were taken as independent variables. This study will help in recommendations for moving forward aiming at integration of biology of rust and smut diseases of wheat with changing climate for development of resistant varieties for resilient and durable management of these pathogens.

关键词： Climate Change Wheat Weeds Insect Pest Disease Ecology

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Bioprospecting plants for natural antioxidants:An overview

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Journal of Coastal Life Medicine 2016年第10期4卷 824-832页

作者： Huma Qureshi muhammad arshad Wajiha Seerat Faryal Kabir Sammer Fatima Department of Botany Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi 46300Pakistan Department of Biochemistry and Biotechnology Pir Mehr Ali Shah Arid Agriculture UniversityRawalpindi 46300Pakistan Department of Botany University of GujratHafiz Hayat CampusGujrat 50800Pakistan

Reactive oxygen species damage cellular proteins and lipids or form DNA adducts when present in high concentration that promotes carcinogenic *** have been the primary therapy for such ailments since ancient *** paper reviews some medicinal plants having antioxidant activities useful for healing cancer,cardiovascular diseases and neuro-protection.A brief overview of the use of medicinal plants and their main constituents effective against reactive oxygen species-based diseases are *** overview will attract the interest of investigators aiming at the design of novel therapeutic approaches for the treatment of various reactive oxygen species-based conditions.

关键词： Medicinal plants Anticancer Neuroprotective Cardioprotectant

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An Insight into Different Strategies for Control and Prophylaxis of Fasciolosis:A Review

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Journal of Advances in International Veterinary Research 2022年第1期4卷 5-14页

作者： hafiz muhammad Rizwan muhammad Sohail Sajid Haider Abbas Sadia Ghazanfer Mamoona arshad Section of Parasitology Department of PathobiologyKBCMA College of Veterinary and Animal SciencesNarowalSub-campus UVASLahorePakistan Department of Parasitology University of Agriculture FaisalabadPakistan Department of Epidemiology and Public Health University of Veterinary and Animal SciencesLahorePakistan

Fasciolosis is one of the important diseases of livestock and has zoonotic *** can cause huge economic losses due to decrease in milk and meat production,decreased feed conversion ratio,and cost of *** and prophylaxis strategies for Fasciola infection are formed based on epidemiological *** control of Fasciola infection can be attained by treating the animals with active *** use of different combinations of anthelmintics with a possible rotation is more effective against immature as well as adult *** of the intermediate host(snail)is vital for the reduction of *** to the rapid growth of snails,the eradication is quite difficult in waterlogged and marshy *** use of different grazing methods and treatment of grazing areas can also help to control fasciolosis.A variety of antigens generated by Fasciola *** been shown to protect against liver fluke *** crude antigens,excretory/secretory,and refined antigens and their combination can be used as prophylactic treatment for the control of *** use of any of the single or combination of these methods can be very effective for the control of fasciolosis.

关键词： Fasciolosis Control Chemotherapy Grazing management Prophylactic treatment

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