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Jamun (Syzygium cumini) seed and fruit extract attenuate hyperglycemia in diabetic rats

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Asian Pacific Journal of Tropical Biomedicine 2017年第8期7卷 750-754页

作者： Ahmad Raza Masood Sadiq Butt Iahtisham-Ul-Haq hafiz ansar rasul suleria National Institute of Food Science & Technology Faculty of FoodNutrition & Home SciencesUniversity of AgricultureFaisalabadPakistan UQ School of Medicine Translational Research InstituteThe University of Queensland

To evaluate the potential of both jamun (Syzygium cumini) seed and fruit extracts against *** Sprague Dawley rats were used to evaluate hypoglycemic potential of jamun extracts. Purposely, jamun fruit and seed’s ethanolic extracts based diets were provided to normal and high sucrose diet induced hyperglycemic/diabetic rats for sixty days. The serum glucose and insulin levels were monitored at monthly intervals to evaluate hypoglycemic effect of jamun *** results of instant research depicted that both seed and fruit extracts reduce the blood glucose level significantly and also regulate the insulin levels in hyperglycemic rats. It was noted that jamun fruit extract attenuated serum glucose levels to 5.35% and 12.29% in normal and hyperglycemic rats, respectively; while insulin levels were improved by 2.82% and 6.19%, correspondingly. Whereas, jamun seed extract reduced glucose to 7.04% & 14.36% and showed 3.56% & 7.24% higher insulin levels in normal & hyperglycemic rats, *** present research revealed that both jamun fruit and seeds have potent prophylactic role against hyperglycemia. In this respect, diet based regimen may be tailored using jamun fruit/seed and their extracts to alleviate hyperglycemia.

关键词： Hyperglycemia Jamun seed and fruit extract Glucose Insulin

Anti-hypercholesterolemic and anti-hyperglycaemic effects of conventional and supercritical extracts of black cumin(Nigella sativa)

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 1014-1022页

作者： Muhammad Jawad Iqbal Masood Sadiq Butt Mir Muhammad Nasir Qayyum hafiz ansar rasul suleria National Institute of Food Science and Technology Faculty of FoodNutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan Department of Agriculture and Food Technology Karakoram International UniversityGilgit-BaltistanPakistan UQ Diamantina Institute Translational Research InstituteFaculty of MedicineThe University of Queensland37 Kent Street WoolloongabbaBrisbaneQLD 4102Australia Department of Food NutritionDietetics and HealthKansas State UniversityManhattanKS 66506USA

Objective: To explore the hypoglycaemic and hypocholesterolemic potential of conventional and supercritical extracts of black ***: Purposely, rat modelling was carried out for 2 months by designing three studies i.e. study Ⅰ(normal rats), study Ⅱ(hyperglycaemic rats) and study Ⅲ(hypercholesterolemic rats). Each study was further divided into three groups based on diet ***, functional diet(contained extract of black cumin prepared by using conventional solvent) and nutraceutical diet(contained extract of black cumin prepared by supercritical fluid extraction system).Results: During whole trial, an abating trend was observed in the level of serum cholesterol with maximum reduction(12.8%) in nutraceutical group of study Ⅲ. Low density lipoprotein and triglyceride level was also lowered maximum in study Ⅲ as17.1% and 11.6%, respectively. Whereas, highest decline in glucose level was in nutraceutical group of study Ⅱ as 11.2%.Conclusions: Inclusion of black cumin extracts in diet significantly lowers the occurrence of hyperglycaemia and hypercholesterolaemia. Furthermore, hypoglycaemic and hypocholesterolemic potential of nutraceutical diet is more prominent as compared to functional diet.

关键词： Black cumin Functional food Nutraceuticals Supercritical extract Hyperglycaemia Hypercholesterolaemia

叶子花和斑叶三角花的植物化学和体外抗微生物活性的比较研究(英文)

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中国天然药物 2012年第6期10卷 441-447页

作者： Sardar Atiq Fawad Nauman Khalid Waqas Asghar hafiz ansar rasul suleria Department of Microbiology Faculty of Health Sciences Hazara University Department of Global Agriculture Graduate School of Agricultural and Life Sciences University of Tokyo School of Agriculture and Food Sciences Faculty of Sciences University of Queensland National Institute of Food Science and Technology University of Agriculture Faisalabad Pakistan

AIM: To study the qualitative analysis of phytochemicals and antibacterial activity of the ethanolic and methanolic extracts of Bougainvillea spectabilis and Bougainvillea variegata leaves. METHODS: Phytochemical constituents were determined qualitatively by the Harborne method, while antimicrobial activities were determined by measuring the zone of inhibition on Mueller Hinton Agar. RESULTS: The maximum inhibitory effects were obtained against the Gram positive microbe Staphylococcus aureus for the methanolic extracts of both B. spectabilis [(28.54 ± 0.18) mm] and B. variegata [(21.97 ± 0.06) mm]. The Gram negative microbes Proteus vulgaris [(16.00 ± 0.15) mm] and Serratia marcescens [(16.00 ± 0.06) mm] gave maximum inhibitory effects for the ethanolic extracts of B. variegata, while Salmonella typhimurium [(17.26 ± 0.12) mm] gave a maximum zone of inhibition for the methanolic extract of B. *** inhibitory effects were observed for the extracts of B. spectabilis or B. variegate against Enterococcus faecalis, Vibro cholera or Klebsiella pneumoniae. CONCLUSION: Both B. spectabilis and B. variegata possess significant antimicrobial activity that, following additional studies, could replace commercially known antibiotics.

关键词： Bougainvillea spectabilis "stand" leaves Bougainvillea variegata leaves Phytochemicals Antimicrobial activity Antibiotics

LC-ESI-QTOF-MS/MS profiling of phenolic compounds in Australian native plums and their potential antioxidant activities

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Food Bioscience 2023年第2期52卷 179-192页

作者： Jiaxun Li Haoyao Liu Muhammad Sohail Mazhar Salman Quddus hafiz ansar rasul suleria School of Agriculture and Food Faculty of Veterinary and Agricultural SciencesThe University of MelbourneParkvilleVIC3010Australia Department of Industry Tourism and Trade of the Northern Territory GovernmentDarwinNT0801Australia

Australian native plums are rich in phenolic compounds,which have significant health-promoting *** are limited recordings and information on the number of species and phenolic content of Australian native ***,the number of species and phenolic content of Australian native plums are not well *** research was conducted to identify and quantify phenolic compounds in the peel,pulp,and seed of three common Australian native plums(Kakadu plum,Davidson plum,Illawarra plum)for applying and promoting the commercial worth of these *** phenolic content(TPC),total flavonoid content(TFC),and total tannins content(TTC)were used to determine the amount of phenolic compounds in these Australian native plums and in vitro experiments,including total antioxidant capacity(TAC),2,2′-Diphenyl-2-picrylhydrazyl(DPPH),Ferric Reducing Antioxidant Power(FRAP),and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS)were used to analyze the antioxidant activities of the *** compounds in the samples were thoroughly analyzed by liquid chromatography-mass spectrometry(LC-ESI-QTOF-MS/MS),and preliminarily identified as phenolic acids(10),flavonoids(23),and other phenolic substances(11).These results show the potent antioxidant properties of the Australian native plums and provide evidence for their potential use as culinary,medicinal,and nutraceutical components.

关键词： Antioxidant activity Australian native plum LC-ESI-QTOF-MS/MS Phenolic compounds