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effect of biochar on the metabolome of soybean seedlings

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Oil crop Sc.ence 2024年第1期9卷 60-68页

作者： Nathalia e.Silva Mariana G.Aguilar Osania e.Ferreira Gleicia M.Paulino Jaqueline c.L.carvalho Lúcia P.S.Pimenta Alan R.T.Machado Programa de Pos-graduaçao em c.encias Ambientais Universidade do Estado de Minas GeraisFrutalMinas Gerais38202-436Brazil Departamento de Química Universidade Federal de Minas GeraisMinas GeraisBelo Horizonte31270-901Brazil Departamento de engenharia Aplicada e Tecnologias Ambientais Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil Departamento de c.encias exatas Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil

The use of biochar can have several effects on plant germination,depending on raw material,preparation method and application ***,the molecular mechanisms that lead to those results have yet to be *** aim of this research was to improve the understanding of these mechanisms by charac.erizing the metabolic.effects of sugarcane bagasse biochar on soybean *** types of biochars were prepared by pyrolysis at 300℃(ScB300),400℃(ScB400)and 600℃(ScB600).Then,each one was mixed into sand at 1%,3%,5%(w/w)dose,*** experiment was performed in 8 days of incubation,when the number of germinated seeds and the average radic.e length were *** evaluate the metabolome,the dry biomass(DB)was subjec.ed to extraction with a mixture of methanol-d4 and D2O(1:1 v/v).The extracts were submitted to metabolomics analysis by Proton Nuc.ear Magnetic *** Relative Germination,Relative Average Radic.e Growth and Germination Index inc.eased in all treatments compared to *** the other hand,the DB inc.eased in all treatments,except for ScB300,at doses of 1%and 3%w/*** metabolites(alanine,asparagine,acetic acid,citric acid,glycerol,fatty acids and sucrose)were identified and quantified in DB extracts as the most influential finding for the separation of *** together,these results strongly suggested that biochars ac.elerated the catabolism of triacylglycerols to sucrose and induced a slight osmotic stress.

关键词： Germination Metabolomics 1H NMR Pyrolysis Sugarcane bagasse

Otolaryngology residency program factors associated with female resident representation

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 7-11页

作者： Julia e.canick James c.campbell charles R.Woodard Lars J.Grimm Alissa M.collins Duke University School of Medicine DurhamNorth CarolinaUSA Department of Head and Neck Surgery&communication Sc.ences Duke University School of MedicineDurhamNorth CarolinaUSA Department of Radiology Duke University School of MedicineDurhamNorth CarolinaUSA

Objective:Female representation in the field of otolaryngology is *** is the first point at which medical school graduates specialize in a chosen field and thus represents an opportunity to recruit and train more female *** study sought to identify program factors associated with greater female representation among resident ***:Departmental websites of all 124 otolaryngology residency programs in the United States and Puerto Rico were examined for a list of *** programs with a resident roster available,the genders of residents,faculty,program directors,and chairpersons were *** and city population for each program was also recorded,as was female resident *** were compared using Pearson chi‐squared univariate ***:1,632 residents and 2,605 faculty were included in the analysis of 109 *** median female resident representation was 40%.Programs with larger faculty sizes,more female faculty,and urban location were associated with an above‐median female resident *** with a larger residency cohort approac.ed significance regarding above‐median female resident *** female faculty representation,program director gender,chairperson gender,and US region were not associated with variation in female resident ***:Greater female otolaryngology residency representation was associated with programs having an urban location and greater numbers of female and total *** was also likely that a larger resident cohort size may affect female resident *** proportions of female faculty,program director,and chairperson gender,as well as the US region,were not associated with variation in female resident gender representation.

关键词： gender program director recruitment residency training

comparison of methods for deriving phenotypes from incomplete observation data with an application to age at puberty in dairy cattle

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Journal of Animal Sc.ence and Biotechnology 2024年第2期15卷 535-545页

作者： Melissa A.Stephen chris R.Burke Jennie e.Pryce Nicole M.Steele Peter R.Amer Susanne Meier claire V.c.Phyn Dorian J.Garrick DairyNZ Ltd 605 Ruakura RoadHamilton 3240New Zealand AL Rae centre for Genetics and Breeding-Massey University RuakuraHamilton 3214New Zealand Agriculture Victoria Research AgriBioCentre for AgriBioscienceBundooraVictoria 3083Australia School of Applied Systems Biology La Trobe UniversityBundooraVictoria 3083Australia AbacusBio DunedinNew Zealand

Background Many phenotypes in animal breeding are derived from incomplete measures,especially if they are challenging or expensive to measure *** include time-dependent traits such as reproductive status,or *** measures for these traits result in phenotypes that are subject to left-,interval-and rightcensoring,where phenotypes are only known to fall below an upper bound,between a lower and upper bound,or above a lower bound *** we compare three methods for deriving phenotypes from incomplete data using age at first elevation(>1 ng/mL)in blood plasma progesterone(AGeP4),which generally coincides with onset of puberty,as an example *** We produced AGeP4 phenotypes from three blood samples collec.ed at about 30-day intervals from approximately 5,000 Holstein–Friesian or Holstein–Friesian×Jersey cross-bred dairy heifers managed in 54 seasonal-calving,pasture-based herds in New *** used these actual data to simulate 7 different visit scenarios,inc.easing the extent of censoring by disregarding data from one or two of the three *** methods for deriving phenotypes from these data were explored:1)ordinal categorical variables which were analysed using categorical threshold analysis;2)continuous variables,with a penalty of 31 d assigned to right-censored phenotypes;and 3)continuous variables,sampled from within a lower and upper bound using a data augmentation *** c.edibility intervals for heritability estimations overlapped across all methods and visit scenarios,but estimated heritabilities tended to be higher when left censoring was *** sires with at least 5 daughters,the correlations between estimated breeding values(eBVs)from our three-visit scenario and each reduced data scenario varied by method,ranging from 0.65 to *** estimated breed effects also varied by method,but breed differences were smaller as phenotype censoring *** Our results indicate that using

关键词： cattle Gibbs sampler Markov-chain Monte carlo(McMc) Puberty

Fetal lung growth predicts the risk for early-life respiratory infections and childhood asthma

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World Journal of Pediatrics 2024年第5期20卷 481-495页

作者： Dimitra e.Zazara Olympia Giannou Steven Sc.epanski Mirja Pagenkemper Anastasios D.Giannou Maike Pincus Ioannis Belios Stefan Bonn Ania c.Muntau Kurt Hec.er Anke Diemert Petra clara Arck Division for experimental Feto-Maternal Medicine Department of Obstetrics and Fetal MedicineUniversity Medical Center Hamburg-Eppendorf(UKE)Martinistraße 5220251HamburgGermany University children’s Hospital UKEHamburgGermany computer engineering and Informatics Department Polytechnic SchoolUniversity of PatrasPatrasGreece Institute of Developmental Neurophysiology Center for Molecular Neurobiology Hamburg(ZMNH)UKEHamburgGermany Department of Obstetrics and Fetal Medicine UKEHamburgGermany Department of General Visceral and Thoracic SurgeryUKEHamburgGermany Section of Molecular Immunology and Gastroenterology Ⅰ.Department of MedicineUKEHamburgGermany Pediatrics and Pediatric Pneumology Practice BerlinGermany Institute of Medical Systems Biology ZMNHUKEHamburgGermany Hamburg center for Translational Immunology UKEHamburgGermany

Background early-life respiratory infections and asthma are major health burdens during *** predicting an inc.eased risk for early-life respiratory diseases are ***,we identified the predictive value of ultrasound-monitored fetal lung growth for the risk of early-life respiratory infections and *** Fetal lung size was serially assessed at standardized time points by transabdominal ultrasound in pregnant women participating in a pregnancy *** between fetal lung growth and respiratory infections in infancy or early-onset asthma at five years were ***-learning models relying on extreme gradient boosting regressor or classifier algorithms were developed to predict respiratory infection or asthma risk based on fetal lung *** model development and validation,study participants were randomly divided into a training and a testing group,respectively,by the employed *** enhanced fetal lung growth throughout pregnancy predic.ed a lower early-life respiratory infection *** sex was associated with a higher risk for respiratory infections in *** lung growth could also predict the risk of asthma at five years of *** designed three machine-learning models to predict the risk and number of infections in infancy as well as the risk of early-onset *** models’R2 values were 0.92,0.90 and 0.93,respectively,underscoring a high accuracy and agreement between the actual and predic.ed *** variables included known risk factors and novel predictors,such as ultrasound-monitored fetal lung *** Sonographic monitoring of fetal lung growth allows to predict the risk for early-life respiratory infections and asthma.

关键词： Asthma child risk early-life respiratory infections Prenatal lung development Sexual dimorphism

Supramolecular Polymerization of Hydrogen-Bonded Trimers in Bulk and Aqueous Medium

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ccS c.emistry 2024年第6期6卷 1458-1465页

作者： Freek V.de Graaf Stef A.H.Jansen Sandra M.c.Schoenmakers Bas van Genabeek Marle e.J.Vleugels Bart W.L.van den Bersselaar e.W.Meijer Ghislaine Vantomme Institute for complex Molecular Systems Laboratory of Macromolecular and Organic ChemistryEindhoven University of Technology5600 MBEindhoven School of c.emistry and RNA Institute University of New South WalesSydneyNew South Wales 2052

Synthetic molecules that form functional noncovalent assemblies in water have received much attention for their potential applications as *** this work,we introduce a novel water-compatible monomer based on the phthalhydrazide moiety that assembles into hydrogen-bonded trimeric *** bulk,the material exhibits a cylindrical nanostructure in the liquid-crystalline phase at elevated temperatures,morphologically distinct from the crystalline lamellar *** water,these molecules effectively form cylinders in a one-dimensional fashion,yielding fibrous *** formation of these supramolecular polymers follows a cooperative mechanism,as evidenced by denaturation *** trimerized pattern represents a new category of aqueous su pramolecular polymers with future prospects for functional complex molecular systems.

关键词： noncovalent c.emistry supramolecular polymers hydrogen bonding cooperativity nanostructure

HI in High Gas-phase Metallicity Dwarf Galaxy WISeA J230615.06+143927.9

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Research in Astronomy and Astrophysics 2024年第1期24卷 292-299页

作者： Yan Guo c.Sengupta T.c.Scott P.Lagos Y.Luo Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Sc.ences University of Science and Technology of ChinaHefei 230026China Institute of Astrophysics and Space Sc.ences(IA Porto) Rua das Estrelas4150-762PortoPortugal

We present resolved Giant Metrewave Radio Telescope H I observations of the high gas-phase metallicity dwarf galaxy WISeA J230615.06+143927.9(z = 0.005)(hereafter J2306) and investigate whether it could be a Tidal Dwarf Galaxy(TDG) candidate. TDGs are observed to have higher metallicities than normal dwarfs. J2306 has an unusual combination of a blue g-r color of 0.23 mag, irregular optical morphology and high-metallicity(12 +log(O/H) = 8.68 ± 0.14), making it an interesting galaxy to study in more detail. We find J2306 to be an H I rich galaxy with a large extended, unperturbed rotating H I disk. Using our H I data we estimated its dynamical mass and found the galaxy to be dark matter(DM) dominated within its H I radius. The quantity of DM, inferred from its dynamical mass, appears to rule out J2306 as an evolved TDG. A wide area environment search reveals J2306 to be isolated from any larger galaxies which could have been the source of its high gas metallicity. Additionally, the H I morphology and kinematics of the galaxy show no indication of a recent merger to explain the *** detailed optical spectroscopic observations of J2306 might provide an answer to how a seemingly ordinary irregular dwarf galaxy achieved such a high level of metal enrichment.

关键词： galaxies:abundances galaxies:dwarf galaxies:irregular radio lines:galaxies radio lines:ISM

Apoer2/Lrp8:the undercover cop of synaptic homeostasis

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Neural Regeneration Research 2024年第12期19卷 2563-2564页

作者： Gordon c.Werthmann Joachim Herz Department of Molecular Genetics and center for Translational Neurodegeneration Research University of Texas Southwestern Medical Center at DallasDallasTXUSA Department of Neurosc.ence Department of Neurology University of Texas Southwestern Medical center at Dallas DallasTXUSA

Apolipoprotein e receptor 2(ApoeR2)is a receptor for the protein Apoe,the most common genetic risk factor for late-onset Alzheimer's disease(AD).It is also a key modulator of syna ptic homeostasis,in part through its effect on the expression of neuronal genes including those implicated in AD and other neuropsychiatric *** this perspective,we highlight several genes affec.ed by ApoeR2 and its alternatively spliced forms and how aberrant expression can be resc.ed by the reintroduction of the ApoeR2 intracellular domain in the mouse hippocampus.

关键词： homeostasis Apoe Alzheimer

The effect of the concentration of plastic waste on the formation of reaction products of the Ti–PeT system

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Green c.emical engineering 2024年第3期5卷 374-382页

作者： Aleksey e.Matveev Tomsk Sc.entific center of the Siberian Branch of the Russian Academy of Sc.ences

The paper presents research results of the synthesis, phase composition, and structure of products obtained by highly exothermic reactions between Ti and c10H8O4mixture components, depending on the plastic waste concentration and Ti powder dispersiveness, density of initial samples, and synthesis medium. The dependence of the phase composition and structure of the synthesis products on the concentration of the polymer（plastic）component in the initial Ti-PeT(c10H8O4) system was found. When the plastic waste content is 20 wt% to 25 wt%, synthesis products contain Tic0.5O0.5–Tic0.6–0.75partic.e agglomerates. Further growth in the polyethylene terephthalate content from 30 wt% to 45 wt% leads to the formation of synthesis products consisting of titanium carbide(Tic0.6–1.0). The gaseous byproduct composition of the exothermic reaction is investigated for the Ti–-c10H8O4mixture composition. It is found that the gaseous by-product mostly contains hydrogen and carbon monoxide as well as impurities of different hydrocarbons（methane, acetylene, ethane, ethene） and carbon dioxide. The maximum adiabatic temperature of the gas combustion temperature is 2080℃, which demonstrates the possibility of using gas as a fuel for energy generation devices. Based on the data obtained, it is possible to c.eate a basis for a new plastic waste technology to fabricate carbide-containing materials.

关键词： Plastic waste Titanium carbide Green technology Hydrogen synthesis

Pelvic fractures in blunt trauma patients:A comparative study

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World Journal of Orthopedics 2024年第5期15卷 418-434页

作者： Alexander A Fokin Joanna Wycech Knight Madison e Tharp Kyler c Brinton Phoebe K Gallagher Justin Fengyuan Xie Russell D Weisz Ivan Puente Trauma and critical care Services Delray Medical CenterDelray BeachFL 33484United States charles e Schmidt college of Medicine Department of SurgeryFlorida Atlantic UniversityBoca RatonFL 33431United States Trauma and critical care Services Broward Health Medical CenterFort LauderdaleFL 33316United States charles e Schmidt college of Medicine Florida Atlantic UniversityBoca RatonFL 33431United States Herbert Wertheim college of Medicine Department of SurgeryFlorida International UniversityMiamiFL 33199United States

BAcKGROUND Pelvic fractures(PF)with concomitant injuries are on the rise due to an inc.ease of high-energy *** of the elderly population with age related comorbidities further complicates the *** organ injuries are kindred with PF due to the proximity to pelvic *** of contrast blush(cB)on computed tomography in patients with PF is considered a sign of active bleeding,however,its clinical significance and association with outcomes is *** To analyze polytrauma patients with PF with a focus on the geriatric population,co-injuries and the value of contrast *** This retrospective cohort study included 558 patients with PF admitted to level 1 trauma center(01/2017-01/2023).Analyzed variables included:Age,sex,mechanism of injury(MOI),injury severity score(ISS),Glasgow coma scale(GcS),abbreviated injury scale(AIS),co-injuries,transfusion requirements,pelvic angiography,embolization,laparotomy,orthopedic pelvic surgery,intensive care unit and hospital lengths of stay,discharge disposition and *** study compared geriatric and non-geriatric patients,patients with and without cB and abdominal *** score matching was implemented in comparison *** PF comprised 4%of all trauma admissions.89 patients had cB.286(52%)patients had concomitant injuries including 93(17%)patients with abdominal *** patients compared to non-geriatric had more falls as MOI,lower ISS and AIS pelvis,higher GcS,less abdominal co-injuries,similar cB and angio-embolization rates,less orthopedic pelvic surgeries,shorter lengths of stay and higher *** propensity matching,orthopedic pelvic surgery rates remained lower(8%vs 19%,Pength of stay shorter,and mortality higher(13%vs 4%,Periatric *** of 89 patients with cB,45(51%)were *** propensity matching,patients with cB compared to without cB had more pelvic angiography(71%vs 12%,P<0.001),hi

关键词： Pelvic fractures Geriatric trauma patients Abdominal co-injuries contrast blush contrast extravasation Angioembolization Polytrauma patients Surgical interventions Blunt trauma external and internal fixation for pelvic stabilization