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The extract of the immature fruit of Poncirus trifoliata induces apoptosis in colorectal cancer cells via mitochondrial autophagy

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Food Science and Human Wellness 2020年第3期9卷 237-244页

作者： Sun-Young Kim Ho-Keun Yi Bong-Sik Yun Dae-Yeol Lee Pyung Han Hwang hae-ryong park Min Sun Kim Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University HospitalJeonju54907South Korea Department of Oral Biochemistry Institute of Oral BioscienceSchool of DentistryJeonbuk National UniversityJeonju54907South Korea Division of Biotechnology and Advanced Institute of Environment and Bioscience Jeonbuk National UniversityIksan-si54596South Korea Department of Pediatrics Jeonbuk National University Medical SchoolJeonju54907South Korea Department of Food Science and Biotechnology Kyungnam UniversityChangwon-si51767South Korea

The immature fruits of Poncirus trifoliate are used as a medicine for the treatment of gastrointestinal disorders,inflammation,and allergies in East ***,their effect on colon cancer cells remains *** investigated the effect of the immature fruit of *** extract on colorectal *** extract of the immature fruit of *** inhibited the proliferation of CT-26 cells compared with untreated cells and it induced autophagy and apoptosis through the protein kinase B/mammalian target of rapamycin and 5'-AMP-activated protein kinase *** number of autophagic vacuoles and autophage markers increased in response to the *** later time-points,apoptosis increased dose/*** CT-26 cells pre-treated a pan-caspase inhibitor prior to *** immature fruit extract treatment,we did not find any change in pro-caspase 3 and pro-PARP ***,in cells pre-treated autphage inhibitor,SQSTM1/p62 and LC3AB,pro-caspase 3 and pro-PARP levels did not *** results indicate the molecular mechanisms that the extract of the immature fruit of *** induces apoptosis in colorectal carcinoma cells by inducing mitochondrial *** this study,we provided a draft for further investigate the use of MEPT for colorectal cancer inhibition.

关键词： Anticancer Autophagy Apoptosis Mitochondria Poncirus trifoliata

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Enriching Middle School Students’Learning Through Digital Storytelling:A Multimodal Analytical Framework

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ECNU Review of Education 2024年第2期7卷 357-383页

作者： Deoksoon Kim Ho-ryong park Oksana Vorobel Boston College Lynch School of Education-Teaching Curriculumand SocietyI40 Commonwealth AvenueChestnut HillMassachusetts 02467-3800US Murray State University City University of New York

Purpose This study investigates middle school students’learning experiences through digital storytelling,applying a multimodal analytical framework to uncover patterns in digital *** study explores how participants engage in pedagogical activities,reflect on their learning experiences,and articulate their voices through digital ***/Approach/Methods Employing qualitative case study methods,we purposefully selected three 12-year-old female students at an urban school in the northern *** of digital stories and other data sources(interviews,classroom observations,and reflective journals)show that the students were engaged in both teaching and *** The findings describe(1)participants and their learning experiences,(2)students’representational and interpersonal constructs as used in their digital stories,and(3)their participation as teachers as well as ***/Value Our multimodal analytical framework illuminates how students express themselves through digital *** discussion focuses on students’learning,their identity development,the effectiveness of the analytical framework,and pedagogical implications.

关键词： Analytical framework digital stories identity middle school students multimodality

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TEAM:Transformer Encoder Attention Module for Video Classification

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Computer Systems Science & Engineering 2024年第2期48卷 451-477页

作者： hae Sung park Yong Suk Choi Department of Artificial Intelligence Hanyang UniversitySeoulKorea Department of Computer Science Hanyang UniversitySeoulKorea

Much like humans focus solely on object movement to understand actions,directing a deep learning model’s attention to the core contexts within videos is crucial for improving video *** the recent study,Video Masked Auto-Encoder(VideoMAE)employs a pre-training approach with a high ratio of tube masking and reconstruction,effectively mitigating spatial bias due to temporal redundancy in full video *** steers the model’s focus toward detailed temporal ***,as the VideoMAE still relies on full video frames during the action recognition stage,it may exhibit a progressive shift in attention towards spatial contexts,deteriorating its ability to capture the main spatio-temporal *** address this issue,we propose an attention-directing module named Transformer Encoder Attention Module(TEAM).This proposed module effectively directs the model’s attention to the core characteristics within each video,inherently mitigating spatial *** TEAM first figures out the core features among the overall extracted features from each *** that,it discerns the specific parts of the video where those features are located,encouraging the model to focus more on these informative ***,during the action recognition stage,the proposed TEAM effectively shifts the VideoMAE’s attention from spatial contexts towards the core spatio-temporal *** attention-shift manner alleviates the spatial bias in the model and simultaneously enhances its ability to capture precise video *** conduct extensive experiments to explore the optimal configuration that enables the TEAM to fulfill its intended design purpose and facilitates its seamless integration with the VideoMAE *** integrated model,i.e.,VideoMAE+TEAM,outperforms the existing VideoMAE by a significant margin on Something-Something-V2(71.3%vs.70.3%).Moreover,the qualitative comparisons demonstrate that the TEAM encourages the model to disregard insignificant featur

关键词： Video classification action recognition vision transformer masked auto-encoder

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Omni-functional simultaneous interfacial treatment for enhancing stability and outgassing suppression of lithium-ion batteries

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Journal of Energy Chemistry 2024年第7期94卷 677-687页

作者： Youbean Lee Chanjoo park Kyoungmin Min Kwangjin park Department of Mechanical Engineering Gachon UniversityGyeonggi-do 13120Republic of Korea Department of Battery Engineering Gachon UniversityGyeonggi-do 13120Republic of Korea School of Mechanical Engineering Soongsil UniversitySeoul 06978Republic of Korea

Ni-rich layered oxides in lithium-ion batteries have problems with gas generation and electrochemical performance reduction due to residual lithium's reaction on the surface with the *** address this issue,in this study,the Acid solvent evaporation(AsE)method has been proposed as a potential method to remove residual lithium while promoting the formation of a new LiNO_(3)-derived coating layer on the cathode *** reduction of residual lithium using the ASE method and the construction of a LiNO_(3)-derived coating layer suppresses gas evolution caused by the side effects of the electrolyte,improves electrochemical performance,and improves thermal stability by facilitating the smooth movement of lithium ***,the structural stability and resistance change due to the LiNO_(3)-derived coating layer effects is guaranteed through cycling and DCIR of the pouch *** a result,compared to Pristine,the capacity retention of coin cells increased by 8%after 100 cycles,and pouch cells increased by 25%after 160 *** addition,after cycling the pouch cell,CO_(2) gas has significantly reduced by about 30%compared to Pristine using gas *** ASE method effectively forms a robust LiNO_(3)-derived coating layer on the cathode active material,which helps minimize electrolyte reactivity,suppress ,CO_(2) emissions,enhance surface structure stability,improve thermal stability,and improveoverallbatteryperformance.

关键词： Lithium-ion batteries Ni-rich NCM Acid solvent evaporation LiNO_(3)-derived coating Gasevolution

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Non-interleaved chiral metasurfaces and neural networks enhance the spatial resolution of polarimetry

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Light(Science & Applications) 2024年第3期13卷 396-398页

作者： Jaewon Jang Minsu park Yeonsang park Department of Physics Chungnam National UniversityDaejeon 34134Korea Institute of Quantum Systems Chungnam National UniversityDaejeon 34134Korea

Non-interleaved chiral metasurfaces for high-spatial-resolution polarimetry are proposed and ***,a convolutional neural network is incorporated to analyze interferometric images with the polarization state of light,an... 详细信息

关键词： parameters chiral resolution

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Iso-propagation vortices: a breakthrough in optical communication technology

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Advanced Photonics 2024年第3期6卷 13-15页

作者： Cherry park Junsuk Rho Pohang University of Science and Technology (POSTECH) Department of Mechanical Engineering Pohang University of Science and Technology (POSTECH) Department of Chemical Engineering Pohang University of Science and Technology (POSTECH) Department of Electrical Engineering POSCO-POSTECH-RIST Convergence Research Center for Flat Optics and Metaphotonics

The rapid advance of optical communication technology requires improvements in data transmission capacity and efficiency. Conventional methods of increasing the transmission capacity such as polarization,wavelength, and spatial mode division multiplexing have shown significant promise, while spatial mode division multiplexing(SDM) offers a new approach through the use of orthogonal spatial modes as distinct communication channels.

关键词： communication optical polarization

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Electrochemically Deposited CZTSSe Thin Films for Monolithic Perovskite Tandem Solar Cells with Efficiencies Over 17%

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Energy & Environmental Materials 2024年第1期7卷 147-152页

作者： Sun Kyung Hwang Ik Jae park Se Won Seo Jae Hyun park So Jeong park Jin Young Kim Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Korea Department of Applied Physics Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials and Systems Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials(RIAM) Seoul National UniversitySeoul 08826Korea

In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2ZnSn(S,Se)4(CZTSSe),they have rarely been demonstrated due to the difficulty in implementing solution-processed perovskite top cell on the rough surface of the bottom ***,we firstly demonstrate an efficient monolithic two-terminal perovskite/CZTSSe tandem solar cell by significantly reducing the surface roughness of the electrochemically deposited CZTSSe bottom *** surface roughness(R_(rms))of the CZTSSe thin film could be reduced from 424 to 86 nm by using the potentiostatic mode rather than using the conventional galvanostatic mode,which can be further reduced to 22 nm after the subsequent ion-milling *** perovskite top cell with a bandgap of 1.65 eV could be prepared using a solution process on the flattened CZTSSe bottom cell,resulting in the efficient perovskite/CZTSSe tandem solar *** the current matching between two subcells involving the thickness control of the perovskite layer,the best performing tandem device exhibited a high conversion efficiency of 17.5%without the hysteresis effect.

关键词： CZTSSe monolithic tandem solar cells perovskite solution process surface roughness control

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Environmentally adaptive reshaping of plant photomorphogenesis by karrikin and strigolactone signaling

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Journal of Integrative Plant Biology 2024年第5期66卷 865-882页

作者： Young-Joon park Bo Eun Nam Chung-Mo park Department of Smart Farm Science Kyung Hee UniversityYongin 17104Korea Departmentof Biological Sciences Seoul National UniversitySeoul 08826Korea Department of Chemistry Seoul National UniversitySeoul 08826Korea

Coordinated morphogenic adaptation of growing plants is critical for their survival and propagation under fluctuating *** morphogenic responses to light and warm temperatures,termed photomorphogenesis and thermomorphogenesis,respectively,have been extensively studied in recent *** photomorphogenesis,plants actively reshape their growth and developmental patterns to cope with changes in light ***,photomorphogenesis is closely associated with diverse growth hormonal ***,accumulating evidence indicates that light-directed morphogenesis is profoundly affected by two recently identified phytochemicals,karrikins(KARs)and strigolactones(SLs).KARs and SLs are structurally related butenolides acting as signaling molecules during a variety of developmental steps,including seed *** receptors and signaling mediators have been identified,and associated working mechanisms have been explored using gene-deficient mutants in various plant *** particular interest is that the KAR and SL signaling pathways play important roles in environmental responses,among which their linkages with photomorphogenesis are most comprehensively studied during seedling *** this review,we focus on how the phytochemical and light signals converge on the optimization of morphogenic *** also discuss molecular mechanisms underlying the signaling crosstalks with an aim of developing potential ways to improve crop productivity under climate changes.

关键词： karrikins morphogenic adaptation photomorphogenesis seedling establishment strigolactones

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An Investigation on Open-RAN Specifications:Use Cases,Security Threats,Requirements,Discussions

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 13-41页

作者： Heejae park Tri-HaiNguyen Laihyuk park Department of Computer Science and Engineering Seoul National University of Science and TechnologySeoul01811Republic of Korea Faculty of Information Technology School of TechnologyVan Lang UniversityHo Chi Minh City70000Vietnam

The emergence of various technologies such as terahertz communications,Reconfigurable Intelligent Surfaces(RIS),and AI-powered communication services will burden network operators with rising infrastructure ***,the Open Radio Access Network(O-RAN)has been introduced as a solution for growing financial and operational burdens in Beyond 5G(B5G)and 6G networks.O-RAN promotes openness and intelligence to overcome the limitations of traditional *** disaggregating conventional Base Band Units(BBUs)into O-RAN Distributed Units(O-DU)and O-RAN Centralized Units(O-CU),O-RAN offers greater flexibility for upgrades and network ***,this openness introduces new security challenges compared to traditional *** existing studies overlook these security requirements of the O-RAN *** gain deeper insights into the O-RAN system and security,this paper first provides an overview of the general O-RAN architecture and its diverse use cases relevant to B5G and 6G *** then delve into specifications of O-RAN security threats and requirements,aiming to mitigate security vulnerabilities *** providing a comprehensive understanding of O-RAN architecture,use cases,and security considerations,thisworkserves as a valuable resource for future research in O-RAN and its security.

关键词： O-RAN architecture use cases security issues security requirements security discussions

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Synergistically coupling of Ni–Fe LDH arrays with hollow Co–Mo sulfide nanotriangles for highly efficient overall water splitting

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Rare Metals 2024年第2期43卷 522-532页

作者： Yun Jae Lee Seung-Keun park Department of Advanced Materials Engineering Chung-Ang UniversityAnseongGyeonggi-do17546Republic of Korea Department of Intelligent Energy and Industry Chung-Ang University84 Heukseok-ro Dongjak-guSeoul06974Republic of Korea Western Seoul Center Korea Basic Science Institute150 Bugahyeon-roSeodaemun-guSeoul03759Republic of Korea

Developing bifunctional catalysts that can catalyze both oxygen evolution reaction(OER)and hydrogen evolution reaction(HER)is pivotal to commercializing large-scale water ***,a novel hollow nanotriangle composed of NiFe LDH-CoMoS_(x) heterojunction(H-CMSx@NiFe LDH)is proposed as a highly efficient bifunctional electrocatalyst for both OER and *** fabricate a heterojunction system,ultra-thin nickel–iron layered double hydroxide(NiFe LDH)nanosheets are uniformly electrodeposited onto a metal–organic framework-derived hollow CoMoS_(x) *** strong coupling of CoMoS_(x) and NiFe LDH catalysts forms the intimate heterojunction interfaces to facilitate interfacial charge transfer,which is favorable to enhance the bifunctional catalytic ***,the large void of CoMoS_(x) nanotriangles and interconnected ultra-thin NiFe LDH nanosheets result in good electrolyte penetration and gas ***,the as-prepared H-CMSx@NiFe LDH on nickel foam(NF)exhibits an impressive catalytic activity and durability for OER and HER activities,delivering a current density of 100 mA·cm^(−2) at the small overpotentials of 214 and 299 mV in OER and HER,***,H-CMSx@NiFe LDH/NF proves to be an effective electrode for an alkaline electrolyzer,as a voltage of only 1.99 V is enough to achieve a current density voltage of only 1.99 V is enough to achieve a current density of 400 mA·cm^(−2) with no degradation in performance over 50 h.

关键词： Overall water splitting Metal-organic framework Molybdenum sulfide Layered double hydroxide Heterojunction

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