检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

内蒙古大学学报（自然科学版） 2024年第2期55卷 193-200页

作者：李妍楠纪惠惠哈达内蒙古大学生命科学学院/牧草与特色作物生物学教育部重点实验室/内蒙古自治区牧草与特色作物生物技术重点实验室呼和浩特010070

泛素化修饰是一种蛋白质降解调控的重要途径,而E3泛素连接酶是泛素化系统的关键组分,结合并决定靶标蛋白。前期研究中从大豆中克隆了一个广谱抗病基因SRC7(SMV resistance cluster 7),其主要功能结构域是TN(TIR-NBS)结构域。本氏烟草(Ni... 详细信息

泛素化修饰是一种蛋白质降解调控的重要途径,而E3泛素连接酶是泛素化系统的关键组分,结合并决定靶标蛋白。前期研究中从大豆中克隆了一个广谱抗病基因SRC7(SMV resistance cluster 7),其主要功能结构域是TN(TIR-NBS)结构域。本氏烟草(Nicotiana benthamiana)中两个编码泛素相关的蛋白NbRGLG2和NbUBXN6均与SRC7^(TN)具有互作。瞬时表达实验中NbRGLG2与NbUBXN6对SMV和TMV无抗性。然而,NbRGLG2与NbUBXN6与SRC7^(TN)共表达时,都会抑制SRC7^(TN)的抗病毒活性。过表达SRC7(Ox-SRC7)本氏烟草中沉默NbRGLG2基因和NbUBXN6基因时,它们可以增强SRC7^(TN)对SMV和TMV的抗性。这些结果显示,NbRGLG2与NbUBXN6负调控SRC7的抗病毒活性。

关键词：泛素连接酶病毒 NbRGLG2 NbUBXN6 负调控

Electro-optically tunable self-focusing and self-defocusing in KTP crystals by a cascaded second-order process

在线全文

学校读者我要写书评

暂无评论

Chinese Optics Letters 2016年第12期14卷 103-107页

作者： Ruma Debnath Digvijay Singh hada Susheel Kumar Beda Ardhendu Saha Department of Electrical Engineering National Institute of TechnologyAgartala

We report the transformation of a linear electro-optically tunable non-phase-matched second-order nonlinear process into a cascaded second-order nonlinear process in a bulk KTP crystal to generate the effect of electrooptically tunable Kerr-type nonlinearity. By applying an electric field on the x–y plane, parallel to the z-axis of the crystal, phase mismatch is created, which introduces a nonlinear phase shift between the launched and reconverted fundamental waves from the generated second harmonic wave. Due to the nonuniform radial intensity distribution of a Gaussian beam, a curvature will be introduced into the fundamental wavefront, which focuses or defocuses the incident beam while propagating through the crystal.

关键词： tunable cascaded optically focusing wavefront applying nonlinearity created harmonic matching

Nanomaterials Synthesis and Effect of Granular Disorders on Electrical Behavior of Lanthanum Manganites

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2011年第8期27卷 691-695页

作者： Avneesh Anshul S.S. Amritphale Sarabjeet Kaur Renu hada Advanced Materials & Processes Research Institute (CSIR) Hoshangabad Road

Comprehensive investigation on the synthesis and electrical transport behaviors of polycrystalline samples of lanthanum manganite due to static disorder was reported. The process parameters were optimized for different batches to yield variable grain sizes. Different sintering conditions and technique like thermal cycling were employed to obtain better grain packing density. The liquid nitrogen and air quenching of the samples were carried out to restrict the grain growth with well defused grain boundary. Variable grain habits and sizes were synthesized by standard solid-state reaction and modified sol-gel synthesis routes. Large variation of grain size, connectivity and packing was observed by varying sintering temperature and synthesis technique. The process dependent grain sizes were observed in the wide range from 20 nm to 1.5 μm by transmission and scanning electron microscopy, The variations in residual resistivity as well as metal-insulator transitions are observed. The observed data were analyzed on the basis of contributions from various dynamic interactions and static disorders.

关键词： Order-disorder effect Sintering Manganites

Are CD45RO^(+)and CD45RA^(-)genuine markers for bovine memory T cells?

在线全文

学校读者我要写书评

暂无评论

Animal Diseases 2022年第4期2卷 213-221页

作者： Kandel Anmol hada Akanksha Xiao Zhengguo Department of Animal and Avian Sciences Universityof MarylandCollege ParkMD 20742USA

Effective vaccination in duces memory T cells,which protect the host against pathogen re-infecti ***,detection of memory T cells is essential for evaluating vaccine efficacy,which was originally dependent on cytokine induction ***,two isoforms of CD45 tyrosine phosphatase,CD45RO expression and CD45RA exclusion(CD45RO^(+)/CD45RA^(-)) are used extensively for detecting memory T cells in *** CD45RO^(+)/CD45RA^(-) markers were first established in humans around three decades ago,and were adopted in cattle soon ***,in the last two decades,some published data in humans have challenged the initial paradigm,and required multiple markers for identifying memoryT *** the contrary,memoryT cell detection in cattle still mostly relies on CD45RO^(+)/CD45RA^(-)despite some con troversial *** this review,we summarized the current literature to exami ne if CD45RO^(+)/CD45RA^(-)are valid markers for detecting memoryT cells in *** seems CD45RA and CD45RO(CD45RA/RO)as markers for identifyi ng bovine memoryT cells are questi on able.

关键词： Cattle Memory Markers T cells CD45RO CD45RA Vaccines Cytokines

Rice receptor-like kinase OsSI-RLK2 inhibits internode elongation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2007年第19期52卷 2657-2663页

作者： WURIYANGHAN hada CHEN LiJuan DONG Yi LEI Gang JIA FaXing ZHANG JinSong CHEN ShouYi National Key Laboratory of Plant Genomics Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China Graduate University of Chinese Academy of Sciences Beijing 100039 China

Receptor-like kinase participates in the early events of plant signal transduction pathways. Previously, we screened the receptor-like kinase genes in rice and performed phylogenetic analyses. In this study, we isolated a receptor-like kinase gene, OsSI-RLK2, from rice. Expression of OsSI-RLK2 was induced by ABA treatment. In vitro analysis indicates that OsSI-RLK2 has Mn2+ dependent autophosphorylation activity, but does not have this activity in the presence of Ca2+ and Mg2+. Transgenic rice with over-expressed OsSI-RLK2 displayed shortened internodes resulting in a dwarf phenotype. Taken together, these results suggest that OsSI-RLK2 may represent a new type of functional RLK in rice that can inhibit the elongation of the internode.

关键词：受体样激活酶 OsSI-RLK2 节间伸长大米

Aluminum potassium sulfate and tannic acid sclerotherapy for Goligher Grades Ⅱ and Ⅲ hemorrhoids: Results from a multicenter study

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2016年第20期8卷 844-849页

作者： Hidenori Miyamoto Takenori hada Gentaro Ishiyama Yoshito Ono Hideo Watanabe Department of Digestive and Pediatric Surgery Institute of Health Bioscience University of Tokushima Graduate School Department of Proctologic Surgery Shiseikai Miyamoto Hospital Division of Proctologic Surgery Onaka Clinic Oshiri Center Department of Anorectal Surgery Sapporo Ishiyama Hospital Department of Surgery Watanabe Hospital

AIM: To show that aluminum potassium sulfate and tannic acid(ALTA) sclerotherapy has a high success rate for Grade Ⅱ and Ⅲ ***: This study was based on the clinical data of 604 patients with hemorrhoids who underwent ALTA sclerotherapy between January 2009 and February 2015. The objective of this study was to assess the efficacy of this treatment for Grades Ⅱ and Ⅲ hemorrhoids. Preoperative and postoperative symptoms, complications and success rate were all assessed retrospectively. Follow-up consisted of a simple questionnaire, physical examination and an anoscopy. Patients were followed-up at one day, one week, two weeks, one month, one year, two years, three years, four years and five years after the ALTA ***: One hundred and sixty-nine patients were diagnosed with Grade Ⅱ hemorrhoids and 435 patients were diagnosed with Grade Ⅲ hemorrhoids. The one year, three year and five year cumulative success rates of ALTA sclerotherapy for Grades Ⅱ and Ⅲ hemo-rrhoids were 95.9% and 93.1%; 89.3% and 83.7%; and 89.3% and 78.2%, respectively. No significant differences were observed in the cumulative success rates after ALTA sclerotherapy between Grades Ⅱ and Ⅲ hemorrhoids(P = 0.09). There were forty-seven post-operative complications(low grade fever; anal pain; urinary retention; rectal ulcer; and others). No serious or life-threatening complications occurred and all cases improved through conservative treatment. At univariate analysis there were no predictive factors of ***: ALTA sclerotherapy has had a high success rate for Grade Ⅱ and Ⅲ hemorrhoids during five years of post-operative treatment. However, additional studies are needed to evaluate the efficacy of this ALTA sclerotherapy in the management of hemorrhoidal disease.

关键词： sclerotherapy Aluminum potassium sulfate and tannic acid Goligher grade Ⅲ Minimally invasive treatment Hemorrhoid

Miniaturized terahertz-driven electron accelerator

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Optoelectronics 2020年第2期13卷 190-190页

作者： Masaki hada Tsukuba Research Center for Interdisciplinary Materials Science University of TsukubaTsukubaIbaraki 305-8573Japan

Terahertz-driven(THz-driven)electron acceleration has recently emerged as a promising approach for developing the future compact ultrashort pulsed electron *** et al.[1]have developed a segmented terahertz electron ac... 详细信息

关键词： electron millimeter terahertz

Intranasal ketamine for the treatment of patients with acute pain in the emergency department

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2016年第1期7卷 19-24页

作者： Roshana Shrestha Samita Pant Ashis Shrestha Kabita hada Batajoo Rashmi Thapa Sumana Vaidya Department of General Practice and Emergency Medicine Manmohan Medical College and Teaching Hospital Department of General Practice and Emergency Medicine Patan Academy of Health Sciences Department of General Practice and Emergency Medicine KIST Medical College Hospital Department of General Practice and Emergency Medicine KMC Medical College Hospital

BACKGROUND:Pain in the emergency department(ED)is common but *** objective of this study was to examine the efficacy and safety of intranasal(IN)ketamine used as an analgesic for patients with acute injury with moderate to severe ***:This study was a cross sectional,observational study of patients more than 8 years old experiencing moderate to severe pain[visual analog score(VAS)>50 mm].The initial dose of IN ketamine was 0.7 mg/kg with an additional dose of 0.3 mg/kg if VAS was more than 50 mm after *** scores and vital signs were recorded at 0,15,30 and 60 ***-effects,sedation level and patient's satisfaction were also *** primary outcome was the number of patients achieving≥20 mm reductions in VAS at 15 *** secondary outcome measures were median reduction in VAS at 15,30 and 60 minutes,changes of vital signs,adverse events,satisfaction of patients,and need for additional ***:Thirty-four patients with a median age of 29.5 years(IQR 17.5–38)were enrolled,and they had an initial median VAS of 80 mm(IQR 67–90).The VAS decreased more than 20 mm at15 minutes in 27(80%)*** reduction of VAS from baseline to 40 mm(IQR 20–40),20 mm(IQR 14–20)and 20 mm(IQR 10–20)respectively at 15,30 and 60 minutes(P<0.001).No critical changes of vital signs were noted and adverse effects were mild and ***:This study showed that IN ketamine is an analgesic choice for patients with acute injury in moderate to severe pain in an overcrowded and resource limited ED.

关键词： Analgesia Intranasal Ketamine Pain Visual analog score

East Asia VLBI Network observations of the TeV Gamma-Ray Burst 190114C

在线全文

学校读者我要写书评

暂无评论

Science Bulletin 2020年第4期65卷 267-271页

作者： Tao An Om Sharan Salafia Yingkang Zhang Giancarlo Ghirlanda Gabriele Giovannini Marcello Giroletti Kazuhiro hada Giulia Migliori Monica Orienti Bong Won Sohn Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China Osserv Astron Brera Ist Nazl AstrofisVia E Bianchi 46Merate I23807Italy Ist Nazl Astrofis Ist RadioastronBologna I40129Italy Department of Physics and Astronomy University of BolognaBologna I40129Italy National Astronomical Observatory of Japan Tokyo 181-8588Japan Korea Astronomy and Space Science Institute Daejeon 34055Republic of Korea Key laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China

Long duration gamma-ray bursts(GRBs)signpost the death of massive stars and the formation of stellar mass black holes(BHs).GRB emission extends from the c-rays(the short-lived prompt emission)through the X-rays and optical/near infrared to the radio bands(the long-lived afterglow emission,reviewed in previous works[1–3]).Very high energy(VHE,EJ100 GeV)emission from GRB afterglows has been long predicted(e.g.,[4–6]).VHE detections provide rich information on GRB shock physics and on the conditions of the emitting zone[7].In particular,the detection of the inverse Compton emission component would constrain the characteristic energy of the shock accelerated electrons responsible for the synchrotron emission and the fraction of the outflow kinetic energy distributed among relativistic particles and,through its amplification,magnetic field.

关键词： GRB 伽马暴