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Embryonal Rhabdomyosarcoma of the Uterine Cervix: Two Cases Report and Literature Review

Open Journal of Obstetrics and Gynecology 2014年第14期4卷 868-873页

作者： Khlifi Abdeljalil Boukadida Asma Mouna Kouira hachani faten Meddeb Sawssen Hidar Samir Bibi Mohamed Essaidi Habib Khairi Hedi Department of Gynecology and Obstetrics University Teaching Hospital Farhat Hached Sousse Tunisia

Introduction:?Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is a rare and extremely aggressive malignant entity. However, prognosis seems to be improved with the use of multimodality approach treatment. Cases: We report the cases of 50- and 51-year-old women, presenting with vaginal bleeding and mass. The two patients underwent radical surgery. Histological examination revealed RMS of uterine cervix. Treatment was effective in the first case but despite the chemotherapy, the second patient died two months later. Discussion and Conclusions: The prognosis of the cervical embryonal RMS depends on clinical and histological features. The current treatment protocols are based on trials done on pediatric patients. Studies on embryonal RMS treatment and outcomes are limited in women over forty years. In patients with unfavorable prognosis characteristics, the multimodality approach including surgery, adjuvant chemo and radiotherapy can be effective. Otherwise, surgery alone can effectively be proposed.

关键词： Embryonal Rhabdomyosarcoma Uterine Cervix Radiation Therapy Chemotherapy Surgery

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Two Spontaneous Pregnancies after Treatment with Ovocyplus<sup>TM</sup>among an Infertile Patient with Two Failed IVF: A Case Report

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Advances in Reproductive Sciences 2015年第2期3卷 27-33页

作者： Olfa Kacem Henda Ben Mustapha Amira Sallem Meriem Harzallah Ines Zidi faten hachani Salma Chachia Abdeljalil Khélifi Ali Saad Mounir Ajina Unit of Reproductive Medicine University Farhat Hached Hospital Sousse Tunisia Department of Obstetrics and Gynecology University Farhat Hached Hospital Sousse Tunisia Laboratories of Cytogenetic Molecular Biology and Human Biology of Reproduction Farhat Hached Hospital Sousse Tunisia

The role of oxidative stress in female reproduction is becoming increasingly important, as recent evidence suggests that it has been implicated in the pathology of infertility of both known and idiopathic origin. Although its efficacy has yet to be well established, supplementation with antioxidants is a new tool being developed in the therapeutic armamentarium for female-factor infertility. We present a case of a spontaneous viable pregnancy in a 37-year-old patient with a history of two consequent In Vitro Fertilization (IVF) failures, occurring after a 5-month antioxidant treatment. This report suggests that oral antioxidants supplementation in female patients may provide an alternative or adjunct to conventional fertility therapies and improve their chances of becoming pregnant.

关键词： Oxidative Stress Antioxidant Female Infertility Pregnancy IVF

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