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Sleep as a window to understand and regulate Alzheimer's disease:emerging roles of thalamic reticular nucleus

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Neural Regeneration Research 2025年第6期20卷 1711-1712页

作者： Haoqi Sun Shiqian Shen Robert J.Thomas m.Brandon Westover Can Zhang Department of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Center for Translational Pain Research Department of AnesthesiaCritical Care and Pain MedicineMassachusetis General HospitalHarvard Medical SchoolBostonMAUSA Division of Pulmonary Critical Care and Sleep MedicineDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Genetics and Aging Research Unit McCance Center for Brain HealthMass General Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

Introduction:Alzheimer 's disease(AD) is a common neurodegenerative disorder and the primary cause of dementia. Considerable evidence supports the “amyloid hypothesis,” stating that the pathogenesis of AD is primarily caused by the deposition of amyloid-β(Aβ), which drives tau phosphorylation, neuroinflammation, and neurodegeneration in the brain. The amyloid hypothesis is strengthened by the significant and moderate benefit of lecanemab, a humanized antibody through an anti-amyloid mechanism,showing slowed clinical decline(van Dyck et al.,2023). The recent positive results of anti-amyloid trials have brought back focus on the amyloid hypothesis through biochemical, genetic, and pharmacological approaches(Zhang, 2023).

关键词： Alzheimer inflammation hypothesis

Solution‑Processed Thin Film Transparent Photovoltaics:Present Challenges and Future Development

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Nano-micro letters 2025年第2期17卷 566-600页

作者： Tianle liu munerah m.S.Almutairi Jie ma Aisling Stewart Zhaohui Xing mengxia liu Bo Hou Yuljae Cho Um-SJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Physics and Astronomy Cardiff UniversityCardiff CF243AAWalesUK Department of Electrical and Computer Engineering Yale UniversityNew HavenCT 06511USA Energy Sciences Institute Yale UniversityWest HavenCT 06516USA Future Photovoltaics Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energy is essential for modern society to sustain economic *** soaring demand for the electrical energy,together with an awareness of the environmental impact of fossil fuels,has been driving a shift towards the utilization of solar ***,traditional solar energy solutions often require extensive spaces for a panel installation,limiting their practicality in a dense urban *** overcome the spatial constraint,researchers have developed transparent photovoltaics(TPV),enabling windows and facades in vehicles and buildings to generate electric *** TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar *** this review,we first briefly introduce wavelength-and non-wavelengthselective strategies to achieve *** of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV *** we highlight recent progress in different types of TPVs,with a particular focus on solution-processed thin-film photovoltaics(PVs),including colloidal quantum dot PVs,metal halide perovskite PVs and organic *** applications of TPVs are also reviewed,with emphasis on agrivoltaics,smart windows and ***,current challenges and future opportunities in TPV research are pointed out.

关键词： Transparent semiconductors Solution-processable transparent solar cell Emerging solar cell materials Buildingintegrated photovoltaics

Analysis of culturable and unculturable microbial community in bensulfuron-methyl contaminated paddy soils

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Journal of Environmental Sciences 2008年第12期20卷 1494-1500页

作者： m.l.Umashankara Department of Sericulture College of YuvarajasMysore University

To investigate the influence of bensulfuron-methyl(BSm)on culturable microbial quantities and unculturable microbial community structures,conventional and molecular biological methods were employed in five BSm treated soils with three replications,respectively. The results obtained with traditional culture-dependent methods showed that a low-level of BSm had slight and transient effects on culturable microorganisms;nevertheless,high concentration of BSm resulted in a dramatic decrease in bacterial colony fo...

关键词： bensulfuron-methyl(BSm) microbial quantities community structures DGGE

Advancing healthcare through laboratory on a chip technology:Transforming microorganism identification and diagnostics

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World Journal of Clinical Cases 2025年第3期13卷 9-19页

作者： Carlos m Ardila Department of Basic Sciences Biomedical Stomatology Research GroupUniversidad de Antioquia U de AMedellín 0057Colombia

In a recent case report in the World Journal of Clinical Cases,emphasized the crucial role of rapidly and accurately identifying pathogens to optimize patient treatment ***-on-a-chip(lOC)technology has emerged as a transformative tool in health care,offering rapid,sensitive,and specific identification of *** editorial provides a comprehensive overview of lOC technology,highlighting its principles,advantages,applications,challenges,and future *** studies from the field have demonstrated the practical benefits of lOC devices in clinical diagnostics,epidemiology,and food *** studies have underscored the superiority of lOC technology over traditional methods,showcasing improvements in speed,accuracy,and *** future integration of lOC with biosensors,artificial intelligence,and data analytics promises further innovation and *** call to action emphasizes the importance of continued research,investment,and adoption to realize the full potential of lOC technology in improving healthcare outcomes worldwide.

关键词： laboratory-on-a-chip microorganism identification Diagnostics Point-ofcare testing Biosensors

The dynamic compensation temperature in a kinetic spin-5/2 Ising model on a hexagonal lattice

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Chinese Physics B 2013年第3期22卷 471-480页

作者： mt Temizer Aysegl Ozkιlι Department of Physics Bozok University66200 YozgatTurkey Institute of Science Bozok University66200 YozgatTurkey

We present a study of the dynamic behavior of a two-sublattice spin-5/2 Ising model with bilinear and crystal-field interactions in the presence of a time-dependent oscillating external magnetic field on alternating layers of a hexagonal lattice by using the Glauber-type stochastic *** lattice is formed by alternate layers of spins σ=5/2 and S=5/*** employ the Glauber transition rates to construct the mean-field dynamic ***,we investigate the time variations of the average sublattice magnetizations to find the phases in the system and then the thermal behavior of the dynamic sublattice magnetizations to characterize the nature（first-or second-order） of the phase transitions and to obtain the dynamic phase transition（DPT） *** also study the thermal behavior of the dynamic total magnetization to find the dynamic compensation temperature and to determine the type of the dynamic compensation *** present the dynamic phase diagrams,including the dynamic compensation temperatures,in nine different *** phase diagrams contain seven different fundamental phases,thirteen different mixed phases,in which the binary and ternary combination of fundamental phases and the compensation temperature or the l-type behavior strongly depend on the interaction parameters.

关键词： kinetic Ising model dynamic phase transition dynamic compensation temperature

Dynamic heating and thermal destruction conditions of quartz particles in polydisperse plasma flow of RF-ICP torch system

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Plasma Science and Technology 2020年第11期22卷 114-126页

作者： l mIAO Yu m GRISHIN Department of Thermophysics Moscow State Technical University N E BaumanMoscow 105005Russia

Numerical simulation of turbulent mixing process of polydisperse quartz particle(particle size distribution in the range of 0.1-0.4 mm)flow with Ar and Ar-H2 plasma generated by radio frequency inductively coupled plasma(RF-ICP)torch has been *** approximate two-stage approach has been proposed to calculate the spatial-temporal distributions of temperature and resulting thermal stress in quartz particles during dynamic heating in polydisperse plasma *** influence of working gas compositions,particle size distributions,injection angle and flow rate of carrier gas on the thermal destruction conditions of quartz particles has been determined under different particle feed *** is found that all the solid quartz particles(0.1-0.4 mm)could be thermal destructed without overheating in RF-ICP torch system,when the hydrogen volume fraction in working gases is more than 1.5%-2%and particle feed rate is in a certain *** values of the maximum and minimum feed rates have been determined under different hydrogen volume *** optimal particle injection angle and flow rate of carrier gas is found around 50°-60°and 160-220 slpm,under which the value of maximum equivalent thermal stress in quartz particles is highest.

关键词： RF-ICP torch dynamic heating thermal destruction hydrogen volume fraction optimal injection conditions

Advanced Functional Electromagnetic Shielding materials:A Review Based on micro‑Nano Structure Interface Control of Biomass Cell Walls

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Nano-micro letters 2025年第1期17卷 98-134页

作者： Yang Shi mingjun Wu Shengbo Ge Jianzhang li Anoud Saud Alshammari Jing luo mohammed A.Amin Hua Qiu Jinxuan Jiang Yazeed m.Asiri Runzhou Huang Hua Hou Zeinhom m.El‑Bahy Zhanhu Guo Chong Jia Kaimeng Xu Xiangmeng Chen Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China State Key laboratory of Efficient Production of Forest Resourced Beijing Forestry UniversityQinghua East Road 35Haidian DistrictBeijing 100083People’s Republic of China Department of Physics Faculty of Sciences‑ArarNorthern Border UniversityArar 91431Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia Shaanxi Key laboratory of macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Integrated Composites lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024People’s Republic of China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr CityCairo 11884Egypt Yunnan Provincial Key laboratory of Wood Adhesives and Glued Products International Joint Research Center for Biomass MaterialsSouthwest Forestry UniversityKunming 650224People’s Republic of China School of Science Henan Agricultural UniversityZhengzhou 450002People’s Republic of China

Research efforts on electromagnetic interference(EmI)shielding materials have begun to converge on green and sustainable biomass *** materials offer numerous advantages such as being lightweight,porous,and *** to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EmI shielding *** concerted efforts on the EmI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EmI shielding *** particular,a more comprehensive study and summary of the factors influencing biomass EmI shielding materials including the pore structure adjustment,preparation process,and micro-control would be *** preparation methods and characteristics of wood,bamboo,cellulose and lignin in EmI shielding field are critically discussed in this paper,and similar biomass EmI materials are summarized and *** composite methods and fillers of various biomass materials were *** paper also highlights the mechanism of EmI shielding as well as existing prospects and challenges for development trends in this field.

关键词： Biomass materials Electromagnetic interference shielding micro-nano structure interface control Conductivity

Kachchh (India) earthquake 2001——causes,severity and impact on groundwater resources

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Journal of Environmental Sciences 2003年第4期15卷 500-505页

作者： m.A.Khan m.l.Sharma CentralAridZoneResearchInstitute CentralAridZoneResearchInstitute Jodhpur342003IndiaJodhpur342003India

Earthquake 2001 in Bhuj region of Kachchh district of Gujarat(India) was one of the most devastating earthquakes in the Indian history. This earthquake has caused severe damage to human life and properties. The impact of earthquake on groundwater resources at many locations was significant. Steep rise in static water level due to earthquake was observed at Bhachau and Chandarani. At other location groundwater followed the declining trend.

关键词： earthquake geology groundwater Bhuj, Kachchh

On calculating glacial isostatic adjustment

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Geodesy and Geodynamics 2024年第5期15卷 441-452页

作者： l.m.Cathles Cornell University IthacaNY 14853USA

modeling the earth's fluid and elastic response to the melting of the glaciers of the last ice age is the most direct way to infer the earth's radial viscosity ***,we compare two methods for calculating the viscoelastic response to surface *** one,the elastic equation of motion is converted to a viscoelastic equation using the Correspondence *** the other,elastic deformation is added to the viscous flow as isostatic adjustment *** two modeling methods predict adjustment histories that are different enough to potentially impact the interpretation of the observed glacial isostatic adjustment(GIA).The differences arise from buoyancy and whether fluid displacements are subjected to hydrostatic *** methods agree if they use the same equations and boundary *** origin of the differences is determined by varying the boundary conditions and pre-stress application.

关键词： Glacial isostatic adjustment Viscoelastic normal modes Hydrostatic pre-stress Elastic buoyancy Correspondence principle