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Journal of Ocean University of China 2024年第1期23卷 216-220页

作者： yu Guihong ZHOU Luning wu Guangwei LI Dehai Shandong Province Key Laboratory of Applied Mycology and Qingdao International Center on Microbes Utilizing BiogasSchool of Life SciencesQingdao Agricultural UniversityQingdao 266109China School of Medicine and Pharmacy and Sanya Oceanographic InstitutionOcean University of ChinaQingdao 266003China College of Chemical Engineering Nanjing Forestry UniversityNanjing 210037China Laboratory for Marine Drugs and Bioproducts Laoshan LaboratoryQingdao 266237China

Two new dihydropyrones,rhytismatones C(1)and D(2),and a known compound,penicillenol A1(3),were isolated from the co-culture broth of the deep-sea-derived fungus Penicillium crustosum PRB-2 and Suaeda salsa-derived endophytic fungus Peni-cillium citrinum *** structures were elucidated through comprehensive analysis of nuclear magnetic resonance(NMR)spectra and mass *** absolute configurations of new compounds were determined by calculating the electronic circular di-chroism(ECD)***-MS data showed that compounds 1–3 could only be detected in the media of co-culture,suggesting new biosynthetic pathways were activated in the co-cultured *** 1 showed obvious antibacterial activities against Pro-teus ***-1002 and Bacillus subtilis MMBC-1004 with minimum inhibitory concentration(MIC)both at 25μmolL^(-1).

关键词： co-culture Penicillium crustosum Penicillium citrinum dihydropyrones antibacterial activity

Spatially explicit reconstruction of cropland cover in Europe from AD 1800 to 2000

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Science China Earth Sciences 2024年第9期67卷 2953-2971页

作者： Jun LI yu YE Xiuqi FANG Diyang ZhaNG Zhilei wu Faculty of Geographical Science Beijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China College of Geographical Science Qinghai Normal UniversityXining 810016China

One of the challenges in global change research is the significant uncertainty in global historical land use and land cover(LUCC)datasets,which are widely used as foundational *** addition to the regional cropland area reconstructions,improving the grid allocation method is another feasible way to raise the reliability of historical LUCC *** this study,an integrated reconstruction of the national cropland areas over the past 200 years was developed for 36 European *** that,the allocation algorithm was built using physiogeographic variables and historical city sites for accounting for land suitability and cultivation preferences,***,cropland data in Europe with a spatial resolution of 5′×5′at five time sections from AD 1800 to 2000 were generated using the optimal allocation algorithm in accordance with the stages of the regional *** results were as follows:(1)The dominant factors governing the distribution of croplands in Europe vary at different agricultural stages,but the results can be merged *** suitability was more optimal for allocation during the modern agricultural stage(AD 1950 and 2000);the priority index combined with land suitability and cultivation preference was more reasonable for allocation during the traditional agricultural stage(AD 1800).The average of the allocations by priority index and the land suitability could be adopted as the allocation results during the transitional stage(AD 1850 and 1900)because the grids for absolute differences within±10 and±20 percentage points between the results obtained from the above two allocations were above 80% and 95%,respectively,which means the two allocation results could be merged.(2)Over the past 200 years,the total cropland area in Europe first increased to a peak in AD 1900 and then ***,the centre of the higher cropland fraction shifted from the western part of Europe in AD 1800 to the eastern part of the continent after AD 1950.(3)

关键词： Land use and land cover change Historical cropland Gridding allocation Europe Past 200 years

Effects of Diesel Concentration on the Thermal Conductivity,Specific Heat Capacity and Thermal Diffusivity of Diesel-Contaminated Soil

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Journal of Thermal Science 2024年第2期33卷 696-709页

作者： wu yuhao wu yuefei LUO Gubai ZhaNG Teng WANG Qing FAN Liwu SONG Xin yu Zitao Key Laboratory of Clean Energy and Carbon Neutrality of Zhejiang Province Zhejiang UniversityHangzhou310027China State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou310027China Institute of Thermal Science and Power Systems School of Energy EngineeringZhejiang UniversityHangzhou310027China Center Environmental Protection Technology Company Limited Beijing100176China Institute of Soil Science Chinese Academy of SciencesNanjing210008China

High energy consumption is a serious issue associated with in situ thermal desorption(TD)remediation of sites contaminated by petroleum hydrocarbons(PHs).The knowledge on the thermophysical properties of contaminated soil can help predict accurately the transient temperature distribution in a remediation site,for the purpose of energy ***,such data are rarely reported for PH-contaminated *** this study,by taking diesel as a representative example for PHs,soil samples with constant dry bulk density but different diesel mass concentrations ranging from 0% to 20% were prepared,and the variations of their thermal conductivity,specific heat capacity and thermal diffusivity were measured and analyzed over a wide temperature range between 0℃ and 120℃.It was found that the effect of diesel concentration on the thermal conductivity of soil is negligible when it is below 1%.When diesel concentration is below 10%,the thermal conductivity of soil increases with raising the ***,when diesel concentration becomes above 10%,the change of the thermal conductivity of soil with temperature exhibits the opposite *** is mainly due to the competition between soil minerals and diesel,because the thermal conductivity of minerals increases with temperature,whereas the thermal conductivity of diesel decreases with *** analysis results showed that,compared with temperature,the diesel concentration has more significant effects on soil thermal *** of the diesel concentration,with the increase of temperature,the specific heat capacity of soil increases,while the thermal diffusivity of soil *** addition,the results of a control experiment exhibited that the relative differences of the thermal conductivity of the soil samples containing the same concentration of both diesel and a pure alkane are all below 10%,indicating that the results obtained with diesel in this study can be extended to the family of PHs.A theo

关键词： contaminated soil diesel concentration thermal conductivity specific heat capacity thermal diffusivity thermal desorption fractal model

Elevational and temporal patterns of pollination success in distylous and homostylous buckwheats(Fagopyrum)in the Hengduan Mountains

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Plant Diversity 2024年第5期46卷 661-670页

作者： Ling-yun wu Shuang-Quan Huang Ze-yu Tong Faculty of Resources and Environmental Science Hubei UniversityWuhan 430062China Institute of Evolution and Ecology School of Life SciencesCentral China Normal UniversityWuhan 430079China

Reproductive strategies of sexually dimorphic plants vary in response to the ***,we ask whether the sexual systems of Fagopyrum species(i.e.,selfing homostylous and out-crossing distylous)represent distinct adaptive strategies to increase reproductive success in changing alpine *** answer this question,we determined how spatial and temporal factors(e.g.,elevation and peak flowering time)affect reproductive success(i.e.,stigmatic pollen load)in nine wild Fagopyrum species(seven distylous and two homostylous)among 28 populations along an elevation gradient of 1299-3315 m in the Hengduan Mountains,southwestern *** also observed pollinators and conducted hundreds of hand pollinations to investigate inter/intra-morph compatibility,self-compatibility and pollen limitation in four Fagopyrum species(two distylous and two homostylous).We found that Fagopyrum species at higher elevation generally had bigger flowers and more stigmatic pollen loads;lateflowering individuals had smaller flowers and lower pollen *** pollen deposition was more variable in distylous species than in homostylous *** seed set was not pollenlimited in all species,we found that fruit set was much lower in distylous species,which rely on frequent pollinator visits,than in homostylous species capable of autonomous *** findings that pollination success increases at high elevations and decreases during the flowering season suggest that distylous and homostylous species have spatially and temporally distinct reproductive strategies related to environment-dependent pollinator activity.

关键词： Biodiversity hotspot Elevation gradient Fagopyrum Stigmatic pollen load Temporal pattern

Dissipation-Driven Superradiant Phase Transition of a Two-Dimensional Bose-Einstein Condensate in a Double Cavity

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Chinese Physics Letters 2024年第6期41卷 44-48页

作者： Bo-hao wu Xin-Xin Yang yu Chen Wei Zhang Department of Physics and Beijing Key Laboratory of Opto-electronic Functional Materials and Micro-nano Devices Renmin University of ChinaBeijing 100872China Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China Graduate School of China Academy of Engineering Physics Beijing 100193China Beijing Academy of Quantum Information Sciences Beijing 100193China

We study superradiant phase transitions in a hybrid system of a two-dimensional Bose–Einstein condensate of atoms and two cavities arranged with a tilt *** adjusting the loss rate of cavities,we map out the phase diagram of steady states within a mean field *** is found that when the loss rates of the two cavities are different,superradiant transitions may not occur at the same time in the two cavities.A first-order phase transition is observed between the states with only one cavity in superradiance and both in *** the case that both cavities are superradiant,a net photon current is observed flowing from the cavity with small decay rate to the one with large decay *** photon current shows a non-monotonic dependence on the loss rate difference,owing to the competition of photon number difference and cavity field phase *** findings can be realized and detected in experiments.

关键词： Einstein transitions decay

Transcriptomic and cellular decoding of scaffolds-induced suture mesenchyme regeneration

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International Journal of Oral Science 2024年第2期16卷 306-321页

作者： Jiayi wu Feifei Li Peng yu Changhao yu Chuyi han Yitian Wang Fanyuan yu Ling Ye State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Cariology and Endodontics West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Pediatric Dentistry West China Hospital of StomatologySichuan UniversityChengduChina

Precise orchestration of cell fate determination underlies the success of scaffold-based skeletal *** extensive studies on mineralized parenchymal tissue rebuilding,regenerating and maintaining undifferentiated mesenchyme within calvarial bone remain very challenging with limited advances *** knowledge has evidenced the indispensability of rebuilding suture mesenchymal stem cell niches to avoid severe brain or even systematic *** to date,the absence of promising therapeutic biomaterials/scaffolds *** reason lies in the shortage of fundamental knowledge and methodological evidence to understand the cellular fate regulations of *** address these issues,in this study,we systematically investigated the cellular fate determinations and transcriptomic mechanisms by distinct types of commonly used calvarial *** data elucidated the natural processes without scaffold transplantation and demonstrated how different scaffolds altered in vivo cellular responses.A feasible scaffold,polylactic acid electrospinning membrane(PLA),was next identified to precisely control mesenchymal ingrowth and self-renewal to rebuild non-osteogenic suture-like tissue at the defect center,meanwhile supporting proper osteointegration with defect bony ***,transcriptome analysis and cellular mechanisms underlying the well-orchestrated cell fate determination of PLA were *** study for the first time cellularly decoded the fate regulations of scaffolds in suture-bony composite defect healing,offering clinicians potential choices for regenerating such complicated injuries.

关键词： injuries healing suture

CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer

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Genes & Diseases 2024年第4期11卷 381-399页

作者： Ming Shao Qingfei Pan haiyan Tan Jing wu ha Won Lee Andrew D.Huber William C.Wright Ji-Hoon Cho Jiyang yu Junmin Peng Taosheng Chen Department of Chemical Biology and Therapeutics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Computational Biology St.Jude Children's Research HospitalMemphisTN 38105USA Center for Proteomics and Metabolomics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Structural Biology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Developmental Neurobiology St.Jude Children's Research HospitalMemphisTN 38105USA

CYP3A5 is a cytochrome P450(CYP)enzyme that metabolizes drugs and contributes to drug resistance in ***,it remains unclear whether CYP3A5 directly influences cancer *** this report,we demonstrate that CYP3A5 regulates glucose metabolism in pancreatic ductal ***-omics analysis showed that CYP3A5 knockdown re-sults in a decrease in various glucose-related metabolites through its effect on glucose trans-port.A mechanistic study revealed that CYP3A5 enriches the glucose transporter GLUT1 at the plasma membrane by restricting the translation of TXNIP,a negative regulator of ***,CYP3A5-generated reactive oxygen species were proved to be responsible for atten-uating the AKT-4EBP1-TXNIP signaling ***3A5 contributes to cell migration by maintaining high glucose uptake in pancreatic *** together,our results,for the first time,reveal a role of CYP3A5 in glucose metabolism in pancreatic ductal adenocarcinoma and identify a novel mechanism that is a potential therapeutic target.

关键词： Cell migration CYP3A5 Glucose metabolism GLUT1 Pancreatic cancer TXNIP

Effects of hot deformation and in-situ ZrB2 particle on microstructure and tensile performance of AA7085 composite sheets

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Journal of Iron and Steel Research International 2024年第7期31卷 1778-1791页

作者： Jiang-jing wu Xi-zhou Kai Chuang Guan yu-tao Zhao School of Material Science and Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina

To provide a new idea to reduce anisotropy for sheets in the thickness direction by microstructure modification and,mean-while,maintain or even enhance tensile performance,the in-situ ZrB2 particle/AA7085 composite sheets with thicknesses of 1,2,3,and 6 mm were *** as-cast grain size was significantly refined by the heterogeneous nucleus of the ZrB2 *** microstructure results show that severe hot deformation converts as-cast disordered microstructure into a sequential microstructure by crushing the remanent phases and matrix into a fiber *** the solid solution and aging heat treatment,the composite sheets exhibit largely recrystallized grains compared with partially recrystallized grains in the matrix sheets,and weak or even free texture exists in the *** grain size in the composite sheets decreases with the increase in thickness *** the thickness range of 1-3 mm,the composite sheets maintain a similar tensile per-formance as that in matrix sheets,while the strength and ductility in the 6-mm-thick composite sheet are improved.

关键词： Composite sheet Grain structure Texture Dislocation Strengthening

Weighted Probability Density Estimator with Updated Bandwidths

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Journal of Systems Science & Complexity 2024年第2期37卷 886-906页

作者： wu Yi yu Wei WANG Xuejun PRAKASA RAO B L S School of Big Data and Artificial Intelligence Chizhou UniversityChizhou 247000China School of Big Data and Statistics Anhui UniversityHefei 230601China CR Rao Advanced Institute of Mathematics Statistics and Computer ScienceHyderabad 500046India

In this paper,the authors study a class of weighted version of probability density *** is shown that the weighted estimator contains some existing estimators of probability density,no matter they are recursive or *** statistical results including weak consistency,strong consistency,rate of strong consistency,and asymptotic normality are established under some mild ***,the random weighted estimator is also *** numerical simulations and a real data analysis are presented to study the numerical performances of the estimators.

关键词： Asymptotic normality consistency numerical simulation probability density real data analysis updated bandwidths weighted estimator

Microstructure and mechanical properties of a cast TRIP-assisted multiphase stainless steel

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China Foundry 2024年第3期21卷 221-228页

作者： Meng-xin Wang Zi-xiang wu Jing-yu He Xiang Chen School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084China

Stainless steels are used in a wide range of complex environments due to their excellent corrosion *** stainless steels can offer an excellent combination of strength,toughness and corrosion resistance due to the coexistence of different *** microstructure and mechanical properties of a novel cast multiphase stainless steel,composed of martensite,ferrite,and austenite,were investigated following appropriate heat treatment processes:solution treatment at 1,050℃ for 0.5 h followed by water quenching to room temperature,and aging treatment at 500℃ for 4 h followed by water quenching to room *** show reversed austenite is formed by diffusion of Ni element during aging process,and the enrichment of Ni atoms directly determines the mechanical stability of *** austenite with a lower Ni content undergoes a martensitic transformation during plastic *** tensile strength of the specimen exceeds 1,100 MPa and the elongation exceeds 24%after solid solution,and further increases to 1,247 MPa and 25%after aging *** enhancement is due to the TRIP effect of austenite and the precipitation of the nanoscale G-phase pinning dislocations in ferrite and martensite.

关键词： multiphase stainless steel mechanical properties TRIP effect reversed austenite G-phase