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Acoustofluidic separation of prolate and spherical micro-objects

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Microsystems & Nanoengineering 2024年第1期10卷 217-230页

作者： Muhammad soban Khan Mushtaq Ali song ha Lee Keun Young Jang seong Jae Lee Jinsoo Park Department of Mechanical Engineering Chonnam National University77 Yongbong-roBuk-guGwangju 61186Republic of Korea Department of Polymer Engineering The University of Suwon17 Wauan-gilBongdam-eupHwaseongGyeonggi 18323Republic of Korea

Most microfluidic separation techniques rely largely on object size as a separation *** ability to separate micro-objects based on their shape is crucial in various biomedical and chemical ***,we develop an ondemand,label-free acoustofluidic method to separate prolate ellipsoids from spherical microparticles based on traveling surface acoustic wave-induced acoustic radiation force and *** freely rotating non-spherical microobjects were aligned under the progressive acoustic field by the counterrotating radiation torque,and the major axis of the prolate ellipsoids was parallel to the progressive wave *** specific alignment of the ellipsoidal particles resulted in a reduction in the cross-sectional area perpendicular to the wave *** a consequence,the acoustic backscattering decreased,resulting in a decreased magnitude of the radiation *** the variation in radiation force,which depended on the micro-object morphology enabled the acoustofluidic shape-based *** conducted numerical simulations for the wave scattering of spherical and prolate objects to elucidate the working mechanism underlying the proposed method.A series of experiments with polystyrene microspheres,prolate ellipsoids,and peanut-shaped microparticles were performed for *** quantitative analysis of the separation efficiency,we confirmed the high purity and high recovery rate of the proposed acoustofluidic shapebased separation of *** a bioparticle,we utilize Thalassiosira eccentrica to perform shape-based separation,as the species has a variety of potential applications in drug delivery,biosensing,nanofabrication,bioencapsulation and immunoisolation.

关键词： separation spherical rotating

Visible light promoted aerobic selective photo-oxidation of cyclohexene on LaCo_(x)Cu_(1−x)O_(3) catalyst

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Nano Research 2024年第8期17卷 6940-6950页

作者： Xu Guo Liru song Wenyu Wang Fengfeng Li Minh Ngoc ha Jun Tang Qiang Ling Ping Cui Qingping Ke College of Chemistry and Chemical Engineering Anhui University of TechnologyMaanshan 243000China VNU Key Laboratory of Advanced Material for Green Growth Faculty of ChemistryUniversity of ScienceVietnam National UniversityHanoi 100000Vietnam

Heterogeneously catalyzed liquid oxidation of olefins with O_(2) provides an alternative way for synthesizing high-value added ***,we report a straightforward urea-redox and sol-gel process for synthesizing LaCo_(x)Cu_(1−x)O_(3) for aerobic photooxidation of *** research highlights a marked increase in the proportions of Co^(2+) and Cu+species in a low chemical state,as well as enhanced visible light absorption through this *** investigations suggest that the catalytic process,particularly with LaCo_(0.7)Cu_(0.3)O_(3),involves a radical pathway mediated by reactive oxygen *** presence of Cu+/Co^(2+) species and surface oxygen vacancies is proposed to boost O_(2) adsorption and activation on the catalyst,facilitating the formation of ***,Cu^(2+)/Co^(3+) species are thought to aid in generating cyclohexenederived radical *** efficient aerobic oxidation of cyclohexene on LaCo_(0.7)Cu_(0.3)O_(3) catalyst relies on the formation of reactive oxygen species and carbon radicals,facilitated by its strong visible light *** achieves a cyclohexene conversion of 89.4% and selectivity to cyclohex-2-ene-1-one of 72.2%,along with stable recyclability after six *** creation of nano-structured LaCo_(x)Cu_(1−x)O_(3) through the urea-redox and sol-gel process offers a promising avenue for the development of highly efficient catalysts for the aerobic photo-oxidation of cyclohexene to cyclohex-2-ene-1-one in the future.

关键词： perovskite oxide photocatalysis oxidation cyclohexene LaCoCuO_(3) cyclohex-2-ene-1-one

Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn’s disease

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World Journal of stem Cells 2024年第3期16卷 257-266页

作者： Min Young Park Yong sik Yoon Jae ha Park Jong Lyul Lee Chang sik Yu Division of Colon and Rectal surgery Department of SurgeryYonsei University College of MedicineSeoul 03722South Korea Division of Colon and Rectal surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND stem cell transplantation is a promising therapeutic option for curing perianal fistula in Crohn’s disease(CD).Anti-tumor necrotic factor(TNF)therapy combined with drainage procedure is effective as ***,previous studies are limited to proving whether the combination treatment of biologics and stem cell transplantation improves the effect of fistula *** This study aimed to evaluate the long-term outcomes of stem cell transplantation and compare Crohn’s perianal fistula(CPF)closure rates after stem cell transplantation with and without anti-TNF therapy,and to identify the factors affecting CPF closure and *** The patients with CD who underwent stem cell transplantation for treating perianal fistula in our institution between Jun 2014 and December 2022 were *** data were compared according to anti-TNF therapy and CPF *** A total of 65 patients were *** median age of females was 26 years(range:21-31)and that of males was 29(44.6%).The mean follow-up duration was 65.88±32.65 months,and complete closure was observed in 50(76.9%)*** closure rates were similar after stem cell transplantation with and without anti-TNF therapy(66.7%vs 81.6%at 3 year,P=0.098).The patients with fistula closure had short fistulous tract and infrequent proctitis and anorectal stricture(P=0.027,0.002,and 0.008,respectively).Clinical factors such as complexity,number of fistulas,presence of concurrent abscess,and medication were not significant for *** cumulative 1-,2-,and 3-year closure rates were 66.2%,73.8%,and 75.4%,*** Anti-TNF therapy does not increase CPF closure rates in patients with stem cell ***,both refractory and non-refractory CPF have similar closure rates after additional anti-TNF *** tract length,proctitis,and anal stricture are risk factors for non-closure in patients with CPF after stem cell transplantation.

关键词： Crohn’s disease Anus Fistula stem cell transplantation Tumor necrosis factor-alpha inhibitors Infliximab

The impact of green finance,eco-innovation,renewable energy and carbon taxes on CO_(2) emissions in BRICs countries:Evidence from Cs ARDL estimation

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Geoscience Frontiers 2024年第4期15卷 449-458页

作者： Muhammad sadiq Ka Yin Chau Nguyen Tran Thai ha Thi Thu Hien Phan Thanh Quang Ngo Pham Quang Huy Carbon Economy Research Center Fuzhou University of International Studies and TradeFuzhou 350202China school of Accounting and Finance Faculty of Business and LawTaylor’s UniversityMalaysia Faculty of Business City University of MacaoTaipaMacaoChina Faculty of Finance and Banking Van Lang UniversityHo Chi Minh CityVietnam Zhejiang shuren University No.8 Shuren streetHangzhou 310015China school of Government University of Economics Ho Chi Minh City(UEH)Ho Chi Minh City 72407Viet Nam Research Group Public Governance and Developmental Issues University of Economics Ho Chi Minh City(UEH)Ho Chi Minh City 72407Viet Nam Ho Chi Minh City University of Economics and Finance(UEF) Ho Chi Minh CityVietnam University of Economics and Human sciences in Warsaw WarsawPoland

A sharp increase in economic and human development has multiplied the carbon intensity due to which there is a significant need of effective strategies in order to curb carbon ***,the present study aims to examine the effective of green finance,eco-innovation,renewable energy output(REO),renewable energy consumption(REC),and carbon taxes on carbon dioxide(CO_(2))emissions in BRICs countries in the time of ***-sectional autoregressive distributed lag(Cs ARDL)is used to test the connection among the *** estimations of Cs-ARDL approach validates the effectiveness of green finance,eco-innovation,REO,REC,carbon taxes,and industrialization as the relationship of these factors with carbon emissions is negative in nature in BRICs *** on the evidences,the study recommends the formulation of environmentally friendly practices and advancement in green finances to mitigate carbon emissions.

关键词： Green finance Eco-innovation Renewable energyoutput Carbon taxes Environmental degradation CO_(2)emissions

Does environmental policy stringency alter the natural resourcesemissions nexus?Evidence from G-7 countries

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Geoscience Frontiers 2024年第5期15卷 454-466页

作者： Roni Bhowmik Arshian sharif Ahsan Anwar Qasim Raza syed Phan The Cong Ngo Ngan ha school of Business Guangdong University of Foreign StudiesGuangdongPeople’s Republic of China Faculty of Business&Entrepreneurship Daffodil International UniversityDhakaBangladesh Lancashire school of Buiness and Enterprise University of Central LancashirePrestonUnited Kingdom Department of Economics and Finance Sunway Business SchoolSunway UniversitySubang JayaMalaysia Adnan Kassar school of Business Lebanese American UniversityBeirutLebanon University of Economics and Human sciences in Warsaw WarsawPoland College of International studies Korea UniversitySeoulSouth Korea Centre for Business Informatics and Industrial Management(CBIIM) UCSI Graduate Business SchoolUCSI UniversityKuala LumpurMalaysia European University of Lefke LefkeNorthern CyprusTR-10 MersinTurkiye Universiti sains Malaysia Malaysia Department of Business Administration ILMA UniversityKarachiPakistan Faculty of Economics Thuongmai UniversityHanoiViet Nam

Natural resource management is indispensable keeping in view their positive economic impacts as well as their detrimental environmental *** achieve certain sDGs,it is inevitable to manage natural resources through effective policies that help to inhibit adverse environmental *** on this approach,the current empirical analysis aims to probe whether environmental policy stringency intensifies,meagres,and/or halts the abysmal environmental impact of natural resources in G-7 countries(United Kingdom,United states,Canada,Italy,France,Japan,and Germany)for the period from 1990 to *** that end,we rely on the second-generation panel data approaches and panel quantile *** outcomes reveal that natural resources increase carbon dioxide emission whereas the synergy of natural resources and environmental policy stringency plunges emissions across the *** findings suggest adoption of a strict environmental policy for attaining the targets of sGD-08(economic growth),sDG-09(innovations),sDG-11(sustainable cities),sDG-12(responsible consumption of natural resources),and sDG-13(climate action).

关键词： Environmental policy stringency Natural resources CO_(2)emissions G-7 countries

short- and long-term outcomes of surgical treatment in patients with intestinal Behcet’s disease

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World Journal of Gastrointestinal surgery 2024年第2期16卷 429-437页

BACKGROUND Behcet’s disease(BD),a chronic vasculitic disorder affecting multiple organs,is characterized by recurrent oral and genital ulcers,arthritis,vasculitis,and intes-tinal *** intestinal involvement of BD is common in East Asia,the efficacy and long-term outcomes of surgical treatment of intestinal BD still remain to be *** To evaluate the postoperative clinical course of intestinal BD and determine factors associated with its *** Data from patients who underwent surgical treatment for intestinal BD between January 2010 and August 2021 were retrospectively ***’demo-graphics,clinical features,postoperative course,complications,and follow-up data were *** We analyzed 39 surgeries in 31 *** mean patient age was 45.1 years,and the mean interval between the diagnosis of intestinal BD and surgical treatment was 4.9 years(range 1.0-8.0 years).The most common indication for surgery was medical intractability(n=16,41.0%),followed by fistula or abscess(n=11,28.2%).Laparoscopic approaches were used in 19 patients(48.7%),and 5 patients(12.8%)underwent emergency *** most common surgical procedure was ileocecal resection(n=18,46.2%),followed by right colectomy(n=11,28.2%).A diverting stoma was created in only one patient(2.6%).During a mean follow-up period of 45(range 8-72)months,eight cases(20.5%)of recurrence in five patients required *** interval between operations was 12.1 months(range 6.3-17.8 mo).Four patients(10.3%)experienced recurrence within 1 year postoperatively,and all eight recurrences occurred within 2 years of the initial *** reoperation rates at 1 and 3 years were 10.3%and 20.5%,respectively.A redo ileocolic anastomosis was performed in all recurrent *** multivariate Cox regression analysis,emergency surgery[hazard ratio(HR)9.357,95%confidence interval(CI):1.608-54.453,P=0.013]and elevated C-reactive protein(CRP)levels(HR 1.154,95%CI:1.002–1.328,

关键词： Behcet syndrome Intestinal General surgery Recurrence Risk factors

Etanercept-synthesizing adipose-derived stem cell secretome:A promising therapeutic option for inflammatory bowel disease

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World Journal of Gastrointestinal surgery 2024年第3期16卷 882-892页

作者： say-June Kim Ok-Hee Kim ha-Eun Hong Ji Hyeon Ju Do sang Lee Department of surgery Seoul St.Mary’s HospitalCollege of Medicinethe Catholic University of KoreaSeoul 06591South Korea Catholic Central Laboratory of surgery Institute of Biomedical IndustryCollege of Medicinethe Catholic University of KoreaSeoul 06591South Korea Division of Rheumatology Department of Internal MedicineSeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Inflammatory bowel disease(IBD)is a chronic inflammatory condition of the gastrointestinal tract,with tumor necrosis factor(TNF)-αplaying a key role in its ***,a decoy receptor for TNF,is used to treat inflammatory *** secretome derived from adipose-derived stem cells(AsCs)has anti-inflammatory effects,making it a promising therapeutic option for *** To investigate the anti-inflammatory effects of the secretome obtained from AsCs synthesizing etanercept on colon cells and in a dextran sulfate sodium(Dss)-induced IBD mouse *** AsCs were transfected with etanercept-encoding mini-circle plasmids to create etanercept-producing *** secretory material from these cells was then tested for anti-inflammatory effects both in vitro and in a Dss-induced IBD mouse *** This study revealed promising results indicating that the group treated with the secretome derived from etanercept-synthesizing AsCs[Etanercept-secretome(Et-sec)group]had significantly lower expression levels of inflammatory mediators,such as interleukin-6,Monocyte Chemoattractant Protein-1,and TNF-α,when compared to the control secretome(Ct-sec).Moreover,the Et-sec group exhibited a marked therapeutic effect in terms of preserving the architecture of intestinal tissue compared to the *** These results suggest that the secretome derived from AsCs that synthesize etanercept has potential as a therapeutic agent for the treatment of IBD,potentially enhancing treatment efficacy by merging the anti-inflam-matory qualities of the AsC secretome with etanercept's targeted approach to better address the multifaceted pathophysiology of IBD.

关键词： Adipose-derived stem cells Etanercept Inflammatory bowel disease secretome Tumor necrosis factor-α

Aerobic respiration Lactococcus lactis ameliorate salmonella induced infection and intestinal dysfunctions by oxygen-scavenging and maintaining immune balance and regulating intestinal microbiota

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Food science and Human Wellness 2024年

作者： Yulong Zhang han Yang Zhiliang Cheng Hui ha Fei Liu Yuehua Jiao Key Laboratory of Dairy science， Ministry of Education， Food College， Northeast Agricultural University Center of Drug safety Evaluation， Heilongjiang University of Chinese Medicine

salmonella grows better under aerobic conditions as a facultative anaerobic foodborne pathogenic bacteria. The oxygen-scavenging activity of Lactococcus lactis in the intestinal tract is a promising strategy for preventing salmonella infection. In this study， the aerobic respiration requirement and preventive mechanism of Lactococcus lactis subsp. lactis (L. lactis) KLDs 4.0325 in murine models infected by salmonella enterica subsp. enterica serovar Typhimurium (s. Typhimurium) sL1344 were investigated. Results indicate that L. lactis KLDs 4.0325 is capable of aerobic respiratory metabolism in the host intestine when exogenous heme exists， and decrease intestinal oxygen concentration， which in turn trigger autophagy of intestinal cells to reduce s. Typhimurium load， improve gut microbiota composition， alleviate intestinal barrier injury and inflammation response. These results suggest that aerobic respiration L. lactis KLDs 4.0325 can prevent s. Typhimurium infection in a new way in which by restoring intestinal cell hypoxia， maintaining immune balance and regulating intestinal flora.

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Liquid Metal Grid Patterned Thin Film Devices Toward Absorption‑Dominant and strain‑Tunable Electromagnetic Interference shielding

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Nano-Micro Letters 2024年第11期16卷 541-553页

作者： Yuwen Wei Priyanuj Bhuyan suk Jin Kwon sihyun Kim Yejin Bae Mukesh singh Duy Thanh Tran Minjeong ha Kwang‑Un Jeong Xing Ma Byeongjin Park sungjune Park Department of Polymer‑Nano science and Technology Department of Nano Convergence EngineeringJeonbuk National UniversityJeonju 54896Republic of Korea school of Chemical Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Composites Research Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea school of Materials science and Engineering Gwangju Institute of Science and TechnologyGwangju 61005Republic of Korea school of Materials science and Engineering and Sauvage Laboratory for Smart MaterialsHarbin Institute of Technology(Shenzhen)ShenzhenGuangdong 518055People’s Republic of China

The demand of high-performance thin-film-shaped deformable electromagnetic interference(EMI)shielding devices is increasing for the next generation of wearable and miniaturized soft *** highly reflective conductive materials can effectively shield EMI,they prevent deformation of the devices owing to rigidity and generate secondary electromagnetic pollution ***,soft and stretchable EMI shielding thin film devices with absorption-dominant EMI shielding behavior is *** devices consist of liquid metal(LM)layer and LM grid-patterned layer separated by a thin elastomeric film,fabricated by leveraging superior adhesion of aerosol-deposited LM on *** devices demonstrate high electromagnetic shielding effectiveness(sE)(sE_(T) of up to 75 dB)with low reflectance(sER of 1.5 dB at the resonant frequency)owing to EMI absorption induced by multiple internal reflection generated in the LM grid ***,the excellent stretchability of the LM-based devices facilitates tunable EMI shielding abilities through grid space adjustment upon strain(resonant frequency shift from 81.3 to 71.3 GHz@33%strain)and is also capable of retaining shielding effectiveness even after multiple strain *** newly explored device presents an advanced paradigm for powerful EMI shielding performance for next-generation smart electronics.

关键词： Absorption-dominant electromagnetic interference shielding Liquid metals soft and stretchable electronics Thin film devices Tunable electromagnetic interference shielding