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Distribution of the P2X2 receptor and chemical coding in ileal enteric neurons of obese male mice(ob/ob)

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World Journal of Gastroenterology 2014年第38期20卷 13911-13919页

作者： Márcia sanae Mizuno Amanda Rabello Crisma Primavera Borelli Bárbara Tavares schfer Mariana Póvoa silveira Patricia Castelucci Department of Anatomy/Biomedical science Institute University of S?o Paulo Faculty of Pharmaceutical sciences University of S?o Paulo Department of surgery Faculty of Veterinary Medicine and Animal ScienceUniversity of S?o Paulo

AIM:To investigate the colocalization,density and profile of neuronal areas of enteric neurons in the ileum of male obese ***:The small intestinal samples of male mice in an obese group(OG)(C57BL/6J ob/ob)and a control group(CG)(+/+)were *** tissues were analyzed using a double immunostaining technique for immunoreactivity(ir)of the P2X2 receptor,nitric oxide synthase(NOs),choline acetyl transferase(ChaT)and calretinin(Calr).Also,we investigated the density and profile of neuronal areas of the NOs-,ChaT-and Calrir neurons in the myenteric *** neurons were labeled using an NADH-diaphorase histochemical staining ***:The analysis demonstrated that the P2X2receptor was expressed in the cytoplasm and in the nuclear and cytoplasmic membranes only in the *** density values(neuron/cm2)decreased 31%(CG:6579±837;OG:4556±407)and 16.5%(CG:7796±528;OG:6513±610)in the NOs-ir and calretininir neurons in the OG,respectively(Psity of ChaT-ir(CG:6200±310;OG:8125±749)neurons significantly increased 31%in the OG(Psize studies demonstrated that NOs,ChaT,and Calr-ir neurons did not differ significantly between the CG and OG *** examination of NADH-diaphorase-positive myenteric neurons revealed an overall similarity between the OG and ***:Obesity may exert its effects by promoting a decrease in P2X2 receptor expression and modifications in the density of the NOs-ir,ChaT-ir and CalR-ir myenteric neurons.

关键词： Obesity P2X2 receptor Myenteric neurons Chemical coding

1,2,3,4,-氧杂噻二唑-s-氧化物,即1,3,4—恶二唑合成中可以控制的一个中间过程

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染料与染色 1980年第3期 48-49页

作者： E.schinzel N.schónberger 胡琴赫斯特公司赫斯特公司

距今70多年以前人们就已熟知,2,5-二取代1,3,4-恶二唑可以由相当的 N,N′-双酰基肼与亚硫酰二氯加热制得。我们尝试,在0℃下 DMF 中仔细地进行这一闭环试验,结果出乎意外地以良好收率获得了这样的化合物。它们的总体组成相当于“恶二唑+... 详细信息

距今70多年以前人们就已熟知,2,5-二取代1,3,4-恶二唑可以由相当的 N,N′-双酰基肼与亚硫酰二氯加热制得。我们尝试,在0℃下 DMF 中仔细地进行这一闭环试验,结果出乎意外地以良好收率获得了这样的化合物。它们的总体组成相当于“恶二唑+sO2”。光谱测定结果肯定了我们取得的乃是3-酰基-5-芳基-1,2,3,4-氧杂噻二唑-s-氧化物（2）,此后我们又由

关键词： NH 化合物酞基

3种角膜曲率计测量LAsIK术后角膜曲率的结果

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世界核心医学期刊文摘(眼科学分册) 2005年第11期 61-62页

作者： schfer s. Kürzinger C. spraul C.W. Kampmeier J. 陈立军 Augenklini k Universittsklinikum Ulm Prittwitzstraβe 43 89075Ulm GermanyDr.

Background: Postoperative hyperopia is a frequent result of cataract surgery i n eyes after previous myopic keratorefractive surgery. One reason for the undere stimation of intraocular lens (IOL) power is the wrong corneal refractive power measurement obtained by keratometers and corneal topography systems after LAsIK. The aim of this study was to compare the precision of measurements of three dif ferent keratometers after LAsIK. Method: We studied 58 eyes of 34 refractive pat ients aged between 20 and 51 years. The preoperative measurements and the measur ements one month after LAsIK were performed with the Keratometer (Zeiss), the corneal top ograph (Eyesys Technologies) and the IOL-Master (Zeiss). We compared our postop erative measurement results obtained with the three keratometers with the result s obtained by using the clinical history method (chm). Results: The smallest mea n deviation was achieved with the IOL-Master (measured mean±sD: 38.94±1.88 D, vs. chm: 38.35±2.13 D). The Keratometer (Zeiss)-showed a larger deviation (me asured: 39.12±1.76 D, chm 38.34±2.07 D) and the largest deviation was shown wi th the corneal topograph (measured: 39.84±1.85 D, chm: 38.86 ±2.10 D), which m easured in mean one diopter higher than what was obtained utilizing the chm. A p ositive correlation between corrected myopia and the postoperative difference be tween the measured and calculated value for each keratometer was found. Conclusi on: This study demonstrates that with common keratometers central corneal power is measured too high after LAsIK. For IOL calculation in patients after LAsIK, t he wrongly positive deviation from measured central corneal power has to be take n into account.

关键词：

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微创介入治疗的实时X线4D成像引导

国际医学放射学杂志 2013年第4期 405-406页

作者： J. Kuntz R. Gupta s.O. schnberg W. semmler M. Kachelrieβ s. Bartling 董龙春 Department of Medical Physics in Radiology German Cancer Research Center-DKFZIm Neuenheimer Feld 28069120 Heidelberg Germany

目的介绍一项血管内导管介入治疗的实时4D(三维空间加时间)X线引导且电离辐射水平可接受的新技术。方法该技术应用新压缩传感重建低剂量体层数据采集技术并使用原有影像信息。使用基于扫描机架的平板探测系统的原型装置即可实现该技术... 详细信息

目的介绍一项血管内导管介入治疗的实时4D(三维空间加时间)X线引导且电离辐射水平可接受的新技术。方法该技术应用新压缩传感重建低剂量体层数据采集技术并使用原有影像信息。使用基于扫描机架的平板探测系统的原型装置即可实现该技术。对猪(n=5)进行模拟血管造影介入治疗。每个时间基线的辐射剂量与"金标准"X线投照摄影比较。结果目前的影像引导方法缺乏持续的4D校正信息,本技术与之相反,介入器材的空间定位可以通过连续的空间4D引导得以解决;在3D血管造影路径图中,可以准确地追踪导丝的运动和支架的扩张。辐射剂量率为23.8μGy/s,与标准的双平面血管造影X线透视检查的20.6μGy/s的辐射剂量率相似。结论在辐射水平可接受的前提下,实时4DX线影像引导技术具有显著影响微创治疗领域的潜能,使得介入操作更快、更安全,能进行新的更复杂的血管及肿瘤微创治疗操作。要点①实时4D血管造影介入引导是可行的。②应用特殊压缩传感算法的低剂量体层数据采集是可行的。③与4DCT透视相比,此技术可减少辐射剂量至可接受的水平。④一旦该技术得以实现,血管介入可以更快、更安全。⑤或许会有更复杂的介入方法得以发展。

关键词：介入引导 4D成像压缩传感导管室微创

On the electron-beam (EB) irradiation and grafting of acrylic monomers onto EVA copolymers

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Chinese science Bulletin 1997年第18期42卷 1549-1554页

作者： Zhang, s Wang, JQ Xie, LQ Wen, CL BEIJING INsT TECHNOL SCH CHEM ENGN & MAT SCISTATE KEY LAB FLAME RETARDANT MATBEIJING 100081PEOPLES R CHINA

IN an ordinary way the grafting induced by electron and gamma preirradiations widely used for improving the compatibility of polymers in composites gives rise to an enhancement of their mechanical properties. However, very few have been reported in the flame retardancy of polymers using these sorts of techniques. Wilkie investigated the flame retardancy of photo-initiation grafted polymers. An attempt is made in this paper to try to use the EB preirradiation on EVA copolymers with different VA contents and the subsequent grafting with saponification under atmosphere and to expedite the charring of polymers upon heating. Characterization of the flammability of the preirradiated EVA copolymers grafted with acrylic monomers indicates that this approach turns out to be a promising way and worthy of doing.

关键词： electron-beam irradiation grafting flame retardancy EVA copolymers.

Fuzzy Based Adaptive Clustering to Improve the Lifetime of Wireless sensor Network

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China Communications 2019年第12期16卷 56-71页

作者： D.Uma Maheswari s.sudha M.Meenalochani National Institute of Technology

The objective of the recently proposed fuzzy based hierarchical routing protocol F-sch is to improve the lifetime of a Wireless sensor Network. Though the performance of F-sch is better than LEACH, the randomness in CH selection inhibits it from attaining enhanced lifetime. CBCH ensures maximum network lifetime when CH is close to the centroid of the cluster. However, for a widely distributed network, CBCH results in small sized clusters increasing the inter cluster communication cost. Hence, with an objective to enhance the network lifetime, a fuzzy based two-level hierarchical routing protocol is proposed. The novelty of the proposal lies in identification of appropriate parameters used in Cluster Head and super Cluster Head selection. Experiments for different network scenarios are performed through both simulation and hardware to validate the proposal. The performance of the network is evaluated in terms of Node Death. The proposal is compared with F-sch and the results reveal the efficacy of the proposal in enhancing the lifetime of network.

关键词： hierarchical routing node degree centrality network lifetime fuzzy wireless sensor networks

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电弧喷涂高性能防腐耐磨涂层

热喷涂技术 2010年第1期2卷 62-65,72页

作者： J.Wilden s.Jahn s.Reich V.E.Drescher R.Durham M.schütze 刘建明柏林技术大学 DECHEMA

垃圾焚烧厂工件表面通常暴露在含HCl/KCl的高温气氛中,这些高腐蚀性高温气氛是造成焚烧厂高额维护费用的主要原因。使用热喷涂技术对部件表面进行涂层防护可明显提高传统钢材的表面耐腐蚀性能。电弧喷涂由于其易于操作性和低成本,已成... 详细信息

垃圾焚烧厂工件表面通常暴露在含HCl/KCl的高温气氛中,这些高腐蚀性高温气氛是造成焚烧厂高额维护费用的主要原因。使用热喷涂技术对部件表面进行涂层防护可明显提高传统钢材的表面耐腐蚀性能。电弧喷涂由于其易于操作性和低成本,已成为最为成熟的技术之一。要得到可观的腐蚀防护能力,涂层必须有很高的致密度。因此,电弧喷涂必须做出适当调整以适应垃圾焚烧厂的特殊需求。虽然镍基合金和钴基合金代表了当今腐蚀防护的技术水平,但是这些合金非常昂贵。属于同一系列的铁基合金将成为一种经济效益更为可观的防腐蚀材料。最近的研究表明,与铁铬基合金和镍铬基合金相比,铁基合金中加入硅后其耐腐蚀性能得到显著提高。鉴于这一原因,本文开展了对不同成分的铁-铬-硅系合金的研究,重点讨论了该合金的最新研究结果。

关键词：电弧喷涂铁-铬-硅系合金垃圾焚烧厂

基于轻型商用车柴电混合动力总成的模块化平台

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汽车与新动力 2020年第4期3卷 11-14页

作者： [德]s.KRAPF [德]M.HOWLETT [德]B.ENZI [德]W.schÖFFMANN 李媛媛(译) 不详

商用车动力总成的电气化应用已变得日益广泛。欧盟排放法规要求使得一些技术相比以往更具开发潜力,而这些技术对于成本敏感型市场而言过于昂贵。AVL公司提供了1种可用于柴电混合动力总成的模块化平台。该平台基于排放、效率和成本进行... 详细信息

商用车动力总成的电气化应用已变得日益广泛。欧盟排放法规要求使得一些技术相比以往更具开发潜力,而这些技术对于成本敏感型市场而言过于昂贵。AVL公司提供了1种可用于柴电混合动力总成的模块化平台。该平台基于排放、效率和成本进行了重点开发。

关键词：商用车混合动力排放成本

The archaeogenomic validation of saint Ladislaus'relic provides insights into theárpád dynasty's genealogy

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Journal of Genetics and Genomics 2023年第1期50卷 58-61页

作者： Gergely I.B.Varga Lilla Alida Kristóf Kitti Maár Luca Kis Oszkár schütz Orsolya Váradi Bence Kovács Alexandra Gînguță Balázs Tihanyi Péter L.Nagy Zoltán Maróti Emil Nyerki Tibor Török Endre Neparáczki Department of Archaeogenetics Institute of Hungarian ResearchH-1014 BudapestHungary Doctoral school of History University of SzegedSzegedHungary Department of Genetics University of SzegedH-6726 SzegedHungary Department of Biological Anthropology University of SzegedH-6726 SzegedHungary Department of Molecular Biology and Biotechnology Faculty of Biology and GeologyBabes-Bolyai University400006 Cluj-NapocaRomania Praxis Genomics LLC AtlantaUSA Department of Pediatrics and Pediatric Health Center University of SzegedH-6725 SzegedHungary

The house of Arp ad ruled Hungary for more than four centuries,establishing dynastical relationships with numerous European nobleand ruling houses,and giving many Catholic saints and blesseds to the Catholic *** were one of the significant dynasties of Medieval Europe(Krist o and Makk,1996).The knight-king saint Ladislaus I(c.1040-1095,reign:1077-1095)is one of the most outstanding kings of this *** addition to the hand relic(the Holy Right)of King saint stephanus I(c.975-1038,reign:1000/1001-1038),the skull relic in the saint Ladislaus’Herma(Fig.1A-1C)preserved in the Cathedral of Gy or,is one of the most important relics for Hungarians(Klaniczai,2000).

关键词： relic provides insights into the The archaeogenomic validation of saint Ladislaus d dynasty’s genealogy