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Optimized NPK fertilizer recommendations based on topsoil available nutrient criteria for wheat in drylands of China

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Journal of Integrative Agriculture 2024年第7期23卷 2421-2433页

作者： Wenjie Yang Jie Yu Yanhang Li Bingli Jia Longgang Jiang Aijing Yuan Yue ma Ming Huang hanbing Cao Jinshan Liu Weihong Qiu Zhaohui Wang Key Laboratory of Plant Nutrition and Agri-environment in Northwest China Ministry of Agriculture and Rural Affairs/College of Natural Resources and EnvironmentNorthwest A&F UniversityYangling 712100China

The optimized management of crop fertilization is very important for improving crop yield and reducing the consumption of chemical *** nutrient values can be used for evaluating the nutritional status of a crop,and they reflect the nutrient concentrations above which the plant is sufficiently supplied for achieving the maximum potential *** on on-farm surveys of 504 farmers and 60 field experimental sites in the drylands of China,we proposed a recommended fertilization method to determine nitrogen(N),phosphorus(P),and potassium(K)fertilizer input rates for wheat production,and then validated the method by a field experiment at 66 different sites in northern *** results showed that wheat grain yield varied from 1.1 to 9.2 t ha^(-1),averaging 4.6 t ha^(-1),and it had a quadratic relationship with the topsoil(0-20 cm)nitrate N and soil available P contents at ***,yield was not correlated with the inputs of N,P,and K *** on the relationship(exponential decay model)between 95–105%of the relative yield and topsoil nitrate N,available P,and available K contents at wheat harvest from 60 field experiments,the topsoil critical nutrient values were determined as 34.6,15.6,and 150 mg kg^(-1)for soil nitrate N,available P,and available K,***,based on five groups of relative yield(>125%,115–125%,105–115%,95–105%,andhat the new method reduced N fertilizer input by 17.5%(38.5 kg N ha^(-1))and P fertilizer i

关键词： fertilization method dryland wheat soil nutrient critical value soil nitrogen topsoil nutrients

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融合特征优化的跨数据集高光谱图像分类

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中国图象图形学报 2024年第8期29卷 2175-2187页

作者：马晓瑞哈林谌敦斌梅亮王洪玉大连理工大学信息与通信工程学院大连116024 大连理工大学光电工程与仪器科学学院大连116024

目的高光谱图像分类可实现对地物目标的逐像素识别,是对地观测中的关键技术。由于采集环境变迁与成像设备差异等因素的影响,不同高光谱图像特征分布偏移,影响现有模型的跨数据集分类精度。针对此,提出了一种融合特征优化的无监督跨数据... 详细信息

目的高光谱图像分类可实现对地物目标的逐像素识别,是对地观测中的关键技术。由于采集环境变迁与成像设备差异等因素的影响,不同高光谱图像特征分布偏移,影响现有模型的跨数据集分类精度。针对此,提出了一种融合特征优化的无监督跨数据集高光谱图像分类方法。方法提出了基于奇异值抑制的特征均衡策略实现数据内独立优化,通过限制奇异值正则项兼顾特征的可迁移性与可鉴别性;提出了基于隐式增广的特征匹配策略实现数据间特征协同优化,引导源域特征逼近目标域提高模型的泛化性;设计了基于隐式鉴别器的对抗学习框架实现数据间特征类别级优化,提高了预测多样性,实现跨数据集分类。结果实验在Pavia数据集组和HyRANK数据集组上进行,与多种最新的跨数据高光谱图像分类方法进行了对比,在Pavia数据集组中,相比于性能第2的模型,总体精度、平均精度和к系数分别提高了1.75%、3.55%和2.17%;在HyRANK数据集组中,相比于性能第2的模型,总体精度、平均精度和к系数分别提高了6.58%、13.10%和7.96%。同时进行了消融实验,研究了各个模块对高光谱图像分类效果的影响。实验结果表明,每一模块在提高高光谱图像分类效果方面都是有效的。结论本文提出的融合特征优化的跨数据集高光谱图像分类方法可以在无监督的条件下显著提高跨数据集高光谱图像分类精度,提高分类预测的多样性,得到更好的分类效果。

关键词：高光谱图像分类跨数据集分类特征优化领域自适应无监督分类域对抗网络

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An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs

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Bio-Design and manufacturing 2024年第3期7卷 240-261页

作者： Seol-ha Jeong Jarno Hiemstra Patrick V.Blokzijl Rebeca Damian-Ferrara Danilo martins dos Santos Jéssica H.L.da Fonseca Min-Ho Kang Jihyun Kim Dilara Yilmaz-Aykut Mei L.L.Cham-Pérez Jeroen Leijten Su ryon Shin Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA Leijten Lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department of Biomedical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

关键词： 3D bioprinting Bioink Colloidal gels Extrusion printing Oxygen-generating microparticle

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虚拟现实技术在缓和医疗中应用的范围综述

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护理学杂志 2024年第10期39卷 26-29,40页

作者：哈丽娜绳宇马慧颖况莉向书乐中国医学科学院/北京协和医学院护理学院北京100043 中国医学科学院北京协和医院手术室

目的总结虚拟现实技术用于缓和医疗的基本内容,分析其应用效果和现存问题,为进一步规范和优化虚拟现实技术的应用提供依据。方法系统检索PubMed、Embase、CINAHL、Web of Science、Cochrane Library、中国知网、万方数据、维普网、中国... 详细信息

目的总结虚拟现实技术用于缓和医疗的基本内容,分析其应用效果和现存问题,为进一步规范和优化虚拟现实技术的应用提供依据。方法系统检索PubMed、Embase、CINAHL、Web of Science、Cochrane Library、中国知网、万方数据、维普网、中国生物医学文献数据库中的相关研究。检索时间为建库至2023年2月18日,由2名研究人员独立筛选并提取资料。结果共纳入16篇文献。虚拟现实技术干预主要内容要素为个性化视频课程、自然风景视频、特制生命回顾课程的沉浸式和非沉浸式体验,干预的有效性和可行性已得到初步证实。结论虚拟现实技术在缓和医疗中的应用处于起步阶段,具有使用前景。未来仍需要开展大样本、高质量的随机对照试验来验证虚拟现实技术在缓和医疗中的应用效果,为制定最佳虚拟现实技术干预方案提供循证依据。

关键词：缓和医疗安宁疗护虚拟现实技术肿瘤慢性疾病非药物性干预人文关怀范围综述

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Transcriptomic and bioinformatics analysis of the mechanism by which erythropoietin promotes recovery from traumatic brain injury in mice

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Neural Regeneration Research 2024年第1期19卷 171-179页

作者： Weilin Tan Jun ma Jiayuanyuan Fu Biying Wu Ziyu Zhu Xuekang Huang Mengran Du Chenrui Wu Ehab Balawi Qiang Zhou Jie Zhang Zhengbu Liao Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have found that erythropoietin promotes the recovery of neurological function after traumatic brain ***,the precise mechanism of action remains unclea *** this study,we induced moderate traumatic brain injury in mice by intrape ritoneal injection of erythro poietin for 3 consecutive *** sequencing detected a total of 4065 differentially expressed RNAs,including 1059 mRNAs,92 microRNAs,799 long non-coding RNAs,and 2115circular *** Encyclopedia of Genes and Genomes and Gene Ontology analyses revealed that the coding and non-coding RNAs that were differentially expressed after traumatic brain injury and treatment with erythropoietin play roles in the axon guidance pathway,Wnt pathway,and maPK *** competing endogenous RNA networks showed that regulatory relationship between the differentially expressed non-coding RNAs and *** the axon guidance pathway was repeatedly enriched,the expression of Wnt5a and Ephb6,key factors in the axonal guidance pathway,was ***6 expression decreased and Wnt5a expression increased after traumatic brain injury,and these effects were reversed by treatment with erythro *** findings suggest that erythro poietin can promote recove ry of nerve function after traumatic brain injury through the axon guidance pathway.

关键词： axon guidance bioinformatics analysis competing endogenous RNA erythropoietin Gene Ontology Kyoto Encyclopedia of Genes and Genomes non-coding RNA RNA sequencing transcriptomics traumatic brain injury

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High Na-ion conductivity andmechanical integrity of anion-exchanged polymeric hydrogel electrolytes for flexible sodium ion hybrid energy storage

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Susmat 2024年第1期4卷 140-153页

作者： JungWoo Hong harpalsinh H.Rana Jeong Hee Park Jun Su Kim Sang Joon Lee Gun Jang Tae Hoon Kang Kang Ho Shin Sang ha Baek Wooseok Yang Kwang Ho Kim Ju-Hyuk Lee Ho Seok Park School of Chemical Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Clean Energy Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST-SKKU Carbon-Neutral Research Center Sungkyunkwan University(SKKU)SuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea COSMOS LAB/92 Jomaru-ro 385beon-gilBucheon-siRepublic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea

The polymeric gel electrolytes are attractive owing to their higher ionic conductivities than those of dry polymer electrolytes and lowered water activity for enlarged potential ***,the ionic conductivity and mechanical strength of the Na-ion conducting polymeric gel electrolytes are limited by below 20 mS cm−1 and 2.2 ***,we demonstrate Na-ion conducting and flexible polymeric hydrogel electrolytes of the chemically coupled poly(diallyldimethylammonium chloride)-dextrin-N,N′-methylene-bisacrylamide film immersed in NaClO_(4) solution(ex-DDA-Dex+NaClO_(4))for flexible sodium-ion hybrid capacitors(f-NIHC).In particular,the anion exchange reaction and synergistic interaction of ex-DDA-Dex with the optimum ClO_(4)−enable to greatly improve the ionic conductivity up to 27.63 mS cm−1 at 25◦C and electrochemical stability window up to 2.6 V,whereas the double networking structure leads to achieve both the mechanical strength(7.48 MPa)and softness of hydrogel ***,the f-NIHCs with the ex-DDA-Dex+NaClO_(4) achieved high specific and high-rate capacities of 192.04 F g^(−1)at 500 ma g^(−1)and 116.06 F g^(−1)at 10000 ma g^(−1),respectively,delivering a large energy density of 120.03Wh kg^(−1)at 906Wkg^(−1)and long cyclability of 70%over 500 cycles as well as demonstrating functional operation under mechanical stresses.

关键词： anion exchange chemistry flexible energy storage hybrid energy storage hydrogel electrolytes renewable electrolytes sodium storage

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不同非手术治疗方案在子宫腺肌病中的临床效果分析

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宁夏医学杂志 2024年第2期46卷 128-131页

作者：王妍哈春芳李譞马远宁夏医科大学临床医学院宁夏银川750004 宁夏医科大学总医院宁夏银川750004

目的探讨不同非手术治疗方案在子宫腺肌病中的临床效果。方法回顾性分析非手术治疗子宫腺肌病患者临床资料130例,根据主治医师及患者选择治疗方案分为A组(曼月乐组,50例)、B组[促性腺激素释放激素激动剂(GnRha)+曼月乐组,50例]和C组(地... 详细信息

目的探讨不同非手术治疗方案在子宫腺肌病中的临床效果。方法回顾性分析非手术治疗子宫腺肌病患者临床资料130例,根据主治医师及患者选择治疗方案分为A组(曼月乐组,50例)、B组[促性腺激素释放激素激动剂(GnRha)+曼月乐组,50例]和C组(地诺孕素组,30例)。观察各组治疗前与治疗后不同时间的子宫体积变化、月经量、痛经症状缓解情况、不良反应发生率及复发率等,评估临床治疗效果。结果治疗后各时间点子宫体积B组均小于A组,A组均小于C组,差异有统计学意义(P0.05)。结论3组治疗均可以缓解临床症状,但以GnRha+曼月乐效果最佳。

关键词：子宫腺肌症左炔诺孕酮宫内缓释系统地诺孕素促性腺激素抑制激素激动剂

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Type I interferon： the mediator of bacterial infection-induced necroptosis

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Cellular & Molecular Immunology 2013年第1期10卷 4-6页

作者： Qinglin Du Jianping Xie ha-Jeong Kim Xiaojing ma Institute of Modern Biopharmaceuticals School of Life Science Southwest University Chongqing China Oepartment of Microbiololgy and Immunology WeillCornell Medical Collese New York NY USA Sheng Yushou Center of Cell Biology and Immunology School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China |

COMMENTAry Innate immune responses are essential for the host to fight against invading microbes. Innate immune receptors or pattern recog- nition receptors recognize conserved microbial molecules and trigger innate immune res- ponses. Pattern recognition receptors such as Toll-like receptors primarily signal through the adaptor MyD88 to activate NF-~B, while other Toll-like receptors signal v/a TRIF to activate IRF-3 resulting in the expression of type I interferons （IFNs）.a Type I IFNs play a crucial role in antiviral immune responses but are also important for the host response against bac- terial infection.2 Paradoxically.

关键词： Type I interferon bacterial infection-induced necroptosis

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新型冠状病毒Beta变异株S1重组蛋白的制备及免疫效果评价

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中国兽医学报 2024年第6期44卷 1133-1139页

作者：范泽昌冯生梁明征马杉姗金宁一哈卓鲁会军吉林农业大学动物医学院吉林长春130118 中国农业科学院长春兽医研究所吉林长春130122 北京诺思兰德生物技术股份有限公司北京100085

根据CHO细胞密码子偏好性进行SARS-CoV-2 Beta变异株S1基因的优化与合成,并将其克隆至pSN载体,构建重组表达质粒pSN-Beta-S1,转染CHO细胞,获得重组蛋白Beta-S1,通过SDS-PAGE和Western blot方法鉴定重组蛋白Beta-S1的表达,对培养液上清... 详细信息

根据CHO细胞密码子偏好性进行SARS-CoV-2 Beta变异株S1基因的优化与合成,并将其克隆至pSN载体,构建重组表达质粒pSN-Beta-S1,转染CHO细胞,获得重组蛋白Beta-S1,通过SDS-PAGE和Western blot方法鉴定重组蛋白Beta-S1的表达,对培养液上清进行亲和层析纯化。将纯化后的重组蛋白Beta-S1联合氢氧化铝佐剂免疫BALB/c小鼠,检测血清中特异性IgG抗体及其亚型,评价针对SARS-CoV-2不同变异株的交叉中和抗体活性。结果显示,成功构建pSN-Beta-S1重组质粒,经CHO细胞表达系统表达了重组蛋白Beta-S1,重组蛋白条带单一,大小约为120 kDa,纯度可达85%以上,可与SARS-CoV-2 RBD蛋白多克隆抗体和Strep标签单克隆抗体特异性结合。S1重组蛋白对BALB/c小鼠具有良好的免疫原性,第3次免疫后14 d,针对RBD和S1蛋白的特异性IgG抗体效价平均可达1∶66260和1∶133120,抗体亚型偏向于IgG1,针对SARS-CoV-2野生株,Beta、Delta、Omicron BA1和Omicron BA2变异株的中和抗体分别为1∶629、1∶1720、1∶374、1∶77和1∶101。本研究利用CHO细胞表达系统成功制备了SARS-CoV-2 Beta变异株S1重组蛋白,免疫BALB/c小鼠后获得了良好的免疫原性和针对不同变异株的交叉中和抗体活性,为广谱SARS-CoV-2疫苗的研究提供了一定的借鉴意义。

关键词：新型冠状病毒 Beta变异株中国仓鼠卵巢细胞重组蛋白免疫原性

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CCL5 as a potential immunotherapeutic target in triple-negative breast cancer

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Cellular & Molecular Immunology 2013年第4期10卷 303-310页

作者： Dandan Lv Yan Zhang ha-Jeong Kim Lixing Zhang Xiaojing ma Sheng Yushou Center of Cell Biology and Immunology School of Life Science and Biotechnology Shanghai Jiaotong University Shanghai China Department of Microbiology and Immunology Weill Cornell Medical College New York NY USA

Breast cancer （BC） is a leading cause of mortality among women in the world. To date, a number of molecules have been established as disease status indicators and therapeutic targets. The best known among them are estrogen receptor-α （ER-α）, progesterone receptor （PR） and H ER-2/neu. About 15%-20% BC patients do not respond effectively to thera pies targeting these classes of tumor-promoting factors. Thus, additional targets are strongly and urgently sought after in therapy for human BCs negative for ER, PR and HER-2, the so-called triple-negative BC （TNBC）. Recent clinical work has revealed that CC chemokine ligand 5 （CCL5） is strongly associated with the progression of BC, particularly TNBC. How CCL5 contributes to the development of TN BC is not well understood. Experimental animal studies have begun to address the mechanistic issue. In this article, we will review the clinical and laboratory work in this area that has led to our own hypothesis that targeting CCL5 in TNBCs will have favorable therapeutic outcomes with minimal adverse impact on the general physiology.

关键词： triple negative breast cancer CCL5 myeloid derived suppressor cell immunotherapy

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