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Y–Z deformable magnetic ring for the treatment of rectal stricture: A case report and review of literature

World Journal of Gastroenterology 2024年第6期30卷 599-606页

作者： Miao-Miao Zhang Huan-Chen Sha Yuan-fa Qin Yi lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Treatment of postoperative anastomotic stenosis for colorectal cancer is often challenging,especially for patients who do not respond well to *** cases where patients have undergone an enterostomy,the stenosis can be easily resolved through magnetic ***,common magnetic compre-ssion techniques cannot be performed on those without *** design-ed a novel Y–Z deformable magnetic ring(Y–Z DMR)and successfully applied it to a patient with a stenosis rectal anastomosis and without enterostomy after rectal cancer *** SUMMARY We here report the case of a 57-year-old woman who had undergone a laparo-scopic radical rectum resection(Dixon)for rectal ***,she started facing difficulty in defecation 6 months after *** colonoscopy indicated stenosis of the rectal *** balloon dilation was performed six times on ***,the stenosis still showed a trend of gradual *** the patient did not undergo an enterostomy,the conventional endoscopic magnetic compression technique could not be ***,we imple-mented a Y–Z DMR implemented through the anus under single *** magnetic ring fell off nine days after the operation and the rectal stenosis was *** patient was followed up for six months and reported good *** The Y–Z DMR deformable magnetic ring is an excellent treatment strategy for patients with rectal stenosis and without enterostomy.

关键词： Anastomotic stenosis Colorectal cancer Magnetosurgery Magnetic compression technique Magnetic surgery clinic Case report

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Numerical Simulation of Macrosegregation Caused by Thermal–Solutal Convection and Solidification Shrinkage Using ALE Model

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Acta Metallurgica Sinica(English Letters) 2019年第11期32卷 1396-1406页

作者： Kang-Xin Chen Hou-fa Shen Key Laboratory for Advanced Materials Processing Technology Ministry of Education School of Materials Science and Engineering Tsinghua University

Solidifi cation shrinkage has been recognized as an important factor for macrosegregation formation. An arbitrary Lagrangian–Eulerian(ALE) model is constructed to predict the macrosegregation caused by thermal–solutal convection and solidi-fi cation shrinkage. A novel mesh update algorithm is developed to account for the domain change induced by solidifi cation shrinkage. The velocity–pressure coupling between the non-homogenous mass conservation equation and momentum equation is addressed by a modifi ed pressure correction method. The governing equations are solved by the streamline-upwind/Petrov–Galerkin-stabilized fi nite element algorithm. The application of the model to the Pb-19.2 wt%Sn alloy solidifi cation problem is considered. The inverse segregation is successfully predicted, and reasonable agreement with the literature results is obtained. Thus, the ALE model is established to be a highly effective tool for predicting the macrosegregation caused by solidifi cation shrinkage and thermal–solutal convection. Finally, the effect of solidifi cation shrinkage is analyzed. The results demonstrate that solidifi cation shrinkage delays the advance of the solidifi cation front and intensifi es the segregation.

关键词： Macrosegregation Solidification shrinkage Finite element method Arbitrary Lagrangian–Eulerian(ALE)

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IBEA-SVM: An Indicator-based Evolutionary Algorithm Based on Pre-selection with Classification Guided by SVM

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Applied Mathematics(A Journal of Chinese Universities) 2019年第1期34卷 1-26页

作者： LI hao-ran HE fa-zhi YAN Xiao-hu School of Computer Science and Technology Wuhan University State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University

Multi-objective optimization has many important applications and becomes a challenging issue in applied science. In typical multi-objective optimization algorithms, such as Indicator-based Evolutionary Algorithm(IBEA), all of parents and offspring need to be evaluated in every generation, and then the better solutions of them are selected as the next generation candidates. This leads to a large amount of calculation and slows down convergence rate for IBEA related applications. Our discovery is that the evaluation of evolutionary algorithm is a binary classi?cation in nature and a meaningful preselection method will accelerate the convergence rate. Therefore this paper presents a novel preselection approach to improve the performance of the IBEA, in which a SVM(Support Vector Machine) classi?er is adopted to sort the promising solutions from unpromising solutions and then the newly generated solutions are conversely added as train sample to increase the accuracy of the classi?er. Firstly, we proposed an online and asynchronous training method for SVM model with empirical kernel. The initial population is randomly generated among population size, which is used as initial training. In the process of training, SVM classi?er is modi?ed and perfected to adapt to the evolutionary algorithm sample. Secondly, the classi?er divides all the new generated solutions from the whole solution spaces into promising solutions and unpromising ones. And only the promising ones are forwarded for evaluation. In this way, the evaluation time can be greatly reduced and the solution quality can be obviously improved. Thirdly, the promising and unpromising solutions are labeled as new train samples in next generation to re?ne classi?er model. A number of experiments on benchmark functions validates the proposed approach. The results show that IBEA-SVM can signi?cantly outperform previous works.

关键词： multi-objective optimization SVM IBEA training classification

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肺癌放化疗后患者发生肺部感染的危险因素及其风险预测列线图模型构建

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中华医院感染学杂志 2024年第8期34卷 1145-1149页

作者：付金平陈惠赵洁晋发张文君张秀伟南京医科大学附属江宁医院放疗科江苏南京211100 南京医科大学附属江宁医院肿瘤科江苏南京211100 南京医科大学附属江宁医院呼吸科江苏南京211100

目的探究肺癌放化疗后患者发生肺部感染的影响因素,并构建其风险预测列线图模型。方法研究对象为2019年5月-2022年10月南京医科大学附属江宁医院收治的198例肺癌且接受放化疗治疗的患者,根据放化疗期间有无发生肺部感染病例分为感染组7... 详细信息

目的探究肺癌放化疗后患者发生肺部感染的影响因素,并构建其风险预测列线图模型。方法研究对象为2019年5月-2022年10月南京医科大学附属江宁医院收治的198例肺癌且接受放化疗治疗的患者,根据放化疗期间有无发生肺部感染病例分为感染组73例和非感染组125例。采用LASSO回归分析筛选潜在影响因素;采用Logistic回归分析探究患者发生肺部感染的影响因素;列线图模型采用R4.2.6语言“rms”包构建,并通过绘制受试者工作特征(ROC)曲线、校准曲线、决策曲线评价模型的区分度、校准度及有效性。结果采用LASSO回归模型筛选出潜在的影响因素,糖尿病病史、血白蛋白(ALB)、血红蛋白(HGB)、化疗周期>4次、放化疗药物>2种、中性粒细胞和淋巴细胞比值(NLR)、血小板和淋巴细胞比值(PLR)、使用抗菌药物、肺不张、肿瘤患者功能状态评分4次、使用抗菌药物、NLR、PLR是肺癌放化疗患者发生肺部感染的影响因素(P4次、使用抗菌药物、NLR、PLR等,构建的列线图模型对预测肺癌放化疗患者发生肺部感染具有较好的效能。

关键词：肺癌放化疗肺部感染影响因素 Logistic回归分析列线图模型

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Challenges and opportunities in improving left ventricular remodelling and clinical outcome following surgical and trans-catheter aortic valve replacement

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Frontiers of Medicine 2021年第3期15卷 416-437页

作者： Xu Yu Jin Mario Petrou Jiang Ting Hu ed D Nicol John R Pepper Surgical Echo-Cardiology Services Oxford Heart CentreJohn Radcliffe HospitalOxford University Hospitals NHS Foundation TrustOxford OX39DUUK Cardiac Surgical Physiology and Genomics Group Nuffield Division of Clinical Laboratory SciencesRadcliffe Department of MedicineUniversity of OxfordOxford OX39DUUK Department of Cardiac Surgery Royal Brompton HospitalLondon SW36NPUK National Heart and Lung Institute Imperial College LondonLondon SW36LYUK NIHR Imperial Biomedical Research Centre London W21NYUK Department of Cardiology Royal Brompton HospitalLondon SW36NPUK

Over the last half century,surgical aortic valve replacement(SAVR)has evolved to offer a durable and efficient valve haemodynamically,with low procedural complications that allows favourable remodelling of left ventricular(LV)structure and *** latter has become more challenging among elderly patients,particularly following trans-catheter aortic valve implantation(TAVI).Precise understanding of myocardial adaptation to pressure and volume overloading and its responses to valve surgery requires comprehensive assessments from aortic valve energy loss,valvular-vascular impedance to myocardial activation,force-velocity relationship,and myocardial *** hypertrophy and myocardial fibrosis remains as the structural and morphological focus in this *** intervention in asymptomatic aortic stenosis or regurgitation along with individualised management of hypertension and atrial fibrillation is likely to improve patient *** pacing via the His-Purkinje system for conduction abnormalities,further reduction in para-valvular aortic regurgitation along with therapy of angiotensin receptor blockade will improve patient outcome by facilitating hypertrophy regression,LV coordinate contraction,and global vascular *** leaflet thromboses require anticoagulation while impaired access to coronary ostia risks future TAVI-in-TAVI or coronary *** comparable long-term durability and the resolution of TAVI related complications become available,SAVR remains the first choice for lower risk younger patients.

关键词： surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment

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高海拔地区应用可视化精准电生理诊断与经皮低频电刺激治疗缺氧性勃起功能障碍的临床观察

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中华男科学杂志 2024年第2期30卷 132-138页

作者：杨茸茸严积雄陈琦炜王发明冶占虎郭巍西宁市第一人民医院男科青海西宁810000

目的:探讨高海拔缺氧地区应用精准电生理诊断与经皮低频电刺激治疗缺氧性勃起功能障碍(ed)的效果。方法:本研究纳入152例高海拔缺氧地区ed患者,使用可视化精准电生理诊断(医用红外热成像仪)取得相应精准参数,低频电刺激治疗(低频神经肌... 详细信息

目的:探讨高海拔缺氧地区应用精准电生理诊断与经皮低频电刺激治疗缺氧性勃起功能障碍(ed)的效果。方法:本研究纳入152例高海拔缺氧地区ed患者,使用可视化精准电生理诊断(医用红外热成像仪)取得相应精准参数,低频电刺激治疗(低频神经肌肉治疗仪),治疗前后比较IIEF-5评分、NPTR及红外热像图温度(全身及靶器官)的变化。结果:所有患者均顺利完成经皮低频电刺激治疗1~3个疗程。IIEF-5治疗前后对比有显著统计学差异(P1.5℃,属于有效电刺激。随访1~3个月无反复。结论:应用可视化精准电生理诊断,联合经皮低频电刺激、高流量吸氧可有效的提高阴茎海绵体氧供,改善其功能与结构,对缺氧性ed的治疗效果肯定,为治疗缺氧性ed开辟了有效的物理治疗手段。

关键词：勃起功能障碍缺氧 IIEF-5 NPTR 电生理诊断经皮低频电刺激高海拔地区

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髌骨下极粉碎性骨折两种内固定的比较

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中国矫形外科杂志 2024年第14期32卷 1279-1284页

作者：汤俊峰孙良业凤晓翔袁先发管立新谢晓东安徽医科大学附属六安医院安徽六安237000

[目的]比较缝线联合固定与钢丝联合固定髌骨下极粉碎性骨折的临床疗效。[方法]回顾性分析2019年1月—2021年12月本院手术治疗的52例髌骨下极粉碎性骨折患者的临床资料。依据术前医患沟通结果,28例采用缝线联合固定(缝线组),24例采用钢... 详细信息

[目的]比较缝线联合固定与钢丝联合固定髌骨下极粉碎性骨折的临床疗效。[方法]回顾性分析2019年1月—2021年12月本院手术治疗的52例髌骨下极粉碎性骨折患者的临床资料。依据术前医患沟通结果,28例采用缝线联合固定(缝线组),24例采用钢丝联合固定(钢丝组)。比较两组围手术期、随访和影像结果。[结果]所有患者均顺利完成手术,术中均无严重并发症发生。两组切口总长度、术中失血量、切口愈合等级差异无统计学意义(P>0.05),但是,缝线组在手术时间[(60.7±7.8)mim vs(67.0±8.8)min,P=0.009]、术中透视次数[(2.2±0.5)次vs(4.3±0.8)次,P0.05),其余相应时间点,缝线组上述指标均显著优于钢丝组(P0.05);相应时间点,缝线组Insall-Salvati指数显著小于钢丝组(P<0.05),而髌骨长度显著大于钢丝组(P<0.05)。缝线组影像学骨折愈合时间显著早于钢丝组(P<0.05)。[结论]缝线垂直间断NICE结固定联合带线锚钉治疗髌骨下极粉碎性骨折临床疗效优于钢丝联合固定,且手术时间短,恢复快,并发症少,无需二次手术取出。

关键词：髌骨下极骨折缝线带线锚钉钢丝内固定

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Long-term testosterone supplementation is useful for ed Nith testosterone deficiency

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Asian Journal of Andrology 2013年第5期15卷 699-700页

作者： Tao Jiang Lei Zheng Xiao-Ming Su Jin-Qiang Peng Dong-Chen Sun Quan-Lin Li Zhi-Wei Zhang fa-Peng Wang Hui Jiang Department of Urology First Affiliated Hospital of Dalian Medical University Dalian 116011 China Department of Urology Peking University Third Hospital Beijing 100191 China

Dear editor, We present an interesting case of a patient with erectile dysfunction （ed） and testosterone deficiency （TD） who was treated with testoster- one supplementation therapy （TST） in combination with sildenafil for 45 months. The patient continued to respond well even after the discontinuation of sildenafil for 8 months. Major side effects and complications were not reported at the long-term follow-up.

关键词： Long-term testosterone ed testosterone deficiency

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Treatment of pituitary prolactinoma reverses unresponsiveness to PDE5 inhibitor therapy in men with ed and SHPRL

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Asian Journal of Andrology 2013年第6期15卷 847-849页

作者： Tao Jiang Lei Zheng Xiao-Ming Su Jin-Qiang Peng Dong-Cheng Sun Quan-Lin Li Zhi-Wei Zhang fa-Peng Wang Hui Jiang Department of Urology First AffiLiated Hospital of Dalian Medical University Dalian 116011 China

Dear editor, Four patients with erectile dysfunction （ed） induced by pituitary prolactinoma presented to our clinic from 2007 to 2008. The patients had been misdiagnosed nearly 2 years earlier at other hospitals because severe ed was the initial symptom. None of these patients had experi-enced successful and satisfactory intercourse in approximately 2 years despite being treated with numerous medications, including the repeated administration of phosphodiesterase-5 inhibitors （PDE5is）（sildenafil 100 mg and/or tadalafil 20 mg）. However, after successful treatment for pituitary prolactinoma, the response to PDE5is improved dramatically. The four cases are described in this report.

关键词： MALE SEXUAL DYSFUNCTIONS HYPERPROLACTINEMIA DISORDERS

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The Dose-response of Intrathecal Ropivacaine Co-administered with Sufentanil for Cesarean Delivery under Combined Spinal-epidural Anesthesia in Patients with Scarred Uterus

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Chinese Medical Journal 2015年第19期128卷 2577-2582页

作者： Fei Xiao Wen-Ping Xu Yin-fa Zhang Lin Liu Xia Liu Li-Zhong Wang Department of Anesthesia Jiaxing Maternity and Child Care HospitalJiaxingZhejiang 314050China Jiaxing Genetic and Reproductive Medicine Research Institute JiaxingZhejiang 314050China Department of AnesthesiaJiaxing Maternity and Child Care HospitalJiaxingZhejiang 314050China

Background：Spinal anesthesia is considered as a reasonable anesthetic option in lower abdominal and lower limb *** study was to determine the dose-response of intrathecal ropivacaine in patients with scarred uterus undergoing cesarean delivery under combined spinal-epidural ***：Seventy-five patients with scarred uterus undergoing elective cesarean delivery under combined spinal-epidural anesthesia were enrolled in this randomized,double-blinded,dose-ranging *** received 6,8,10,12,or 14 mg intrathecal hyperbaric ropivacaine with 5 μg *** spinal anesthesia was defined as a T4 sensory level achieved with no need for epidural *** 50％ effective dose （ed50） and 95％ effective dose （ed95） were calculated with a logistic regression ***：ed50 and ed95 ofintrathecal hyperbaric ropivacaine for patients with scarred uterus undergoing cesarean delivery under combined spinal-epidural anesthesia （CSEA） were 8.28 mg （95％ confidence interval [CI]：2.28-9.83 mg） and 12.24 mg （95％ CI：10.53-21.88 mg）,***：When a CSEA technique is to use in patients with scarred uterus for an elective cesarean delivery,the ed50 and ed95 of intrathecal hyperbaric ropivacaine along with 5 μg sufentanil were 8.28 mg and 12.24 mg,*** addition,this local anesthetic is unsuitable for emergent cesarean delivery,but it has advantages for ambulatory patients.

关键词： Cesarean Delivery Dose-response Ropivacaine Scarred Uterus Spinal

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