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A Scheme Library-Based Ant Colony Optimization with 2-Opt Local Search for Dynamic Traveling Salesman Problem

Computer Modeling in Engineering & Sciences 2023年第5期135卷 1209-1228页

作者： Chuan Wang Ruoyu Zhu Yi Jiang Weili Liu Sang-woon Jeon Lin Sun Hua Wang College of Software Henan Normal UniversityXinxiang453007China College of Computer and Information Engineering Henan Normal UniversityXinxiang453007China School of Computer Science and Engineering South China University of TechnologyGuangzhou510006China School of Computer Science Guangdong Polytechnic Normal UniversityGuangzhou510665China Department of Military Information Engineering Hanyang UniversityAnsan15588South Korea College of Engineering and Science Institute for Sustainable Industries and Liveable CitiesVictoria UniversityMelbourneVIC 8001Australia

The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to *** paper proposes a scheme library-based ant colony optimization(ACO)with a two-optimization(2-opt)strategy to solve the DTSP *** work is novel and contributes to three aspects:problemmodel,optimization framework,and ***,in the problem model,traditional DTSP models often consider the change of travel distance between two nodes over time,while this paper focuses on a special DTSP model in that the node locations change dynamically over ***,in the optimization framework,the ACO algorithm is carried out in an offline optimization and online application framework to efficiently reuse the historical information to help fast respond to the dynamic *** framework of offline optimization and online application is proposed due to the fact that the environmental change inDTSPis caused by the change of node location,and therefore the newenvironment is somehowsimilar to certain previous *** way,in the offline optimization,the solutions for possible environmental changes are optimized in advance,and are stored in a mode scheme *** the online application,when an environmental change is detected,the candidate solutions stored in the mode scheme library are reused via ACO to improve search efficiency and reduce computational ***,in the algorithm design,the ACO cooperates with the 2-opt strategy to enhance search *** evaluate the performance of ACO with 2-opt,we design two challenging DTSP cases with up to 200 and 1379 nodes and compare them with other ACO and genetic *** experimental results show that ACO with 2-opt can solve the DTSPs effectively.

关键词： Dynamic traveling salesman problem(DTSP) offline optimization and online application ant colony optimization(ACO) two-optimization(2-opt)strategy

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Occurrence of human leukocyte antigen B51-related ankylosing spondylitis in a family:Two case reports

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World Journal of Clinical Cases 2022年第3期10卷 992-999页

作者： Mie Jin Lim Eul Noh Ro-woon Lee Kyong-Hee Jung Won Park Rheumatology/Internal Medicine Inha UniversityIncheon 22332South Korea Radiology Inha UniversityIncheon 22332South Korea

BACKGROUND Ankylosing spondylitis(AS)is strongly associated with the human leukocyte antigen(HLA)B27 *** regions where conventional polymerase chain reaction for HLA typing is available for antigens such as HLA B27 or HLA B51,it is common to perform the HLA B27 test for evaluation of *** HLA B27-associated clustered occurrences of AS have been reported in families,we report the first case series of HLA B51-related occurrences of AS in a *** SUMMARY A father and his daughters were diagnosed with AS and did not have the HLA B27 *** they were positive for HLA B51,they exhibited no signs of Behçet’s disease(BD).Of the five daughters,one had AS,and three,including the daughter with AS,were positive for HLA *** two daughters with the HLA B51 haplotype(excluding the daughter with AS)exhibited bilateral grade 1 sacroiliitis,whereas the daughters without the HLA B51 haplotype did not have ***,this Korean family exhibited a strong association with the HLA B51 haplotype and clinical sacroiliitis,irrespective of the symptoms of *** It is advisable to check for HLA B51 positivity in patients with AS/spondyloarthropathy who test negative for HLA B27.

关键词： Ankylosing spondylitis Spondyloarthropathy Human leukocyte antigen B51 Human leukocyte antigen B27 Sacroiliitis Case report

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Atomic-scaled surface engineering Ni-Pt nanoalloys towards enhanced catalytic efficiency for methanol oxidation reaction

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Nano Research 2020年第11期13卷 3088-3097页

作者： Aixian Shan Shuoyuan Huang haofei Zhao Wengui Jiang Xueai Teng Yingchun Huang Chinping Chen Rongming Wang woon-Ming Lau Beijing Advanced Innovation Center for Materials Genome Engineering Center for Green InnovationBeijing Key Laboratory for Magneto-Photoelectrical Composite and Interface ScienceSchool of Mathematics and PhysicsUniversity of Science and Technology BeijingBeijing100083China Department of Physics Peking UniversityBeijing100871China Shunde Graduate School of University of Science and Technology Beijing Foshan528300China

Surface engineering is known as an effective strategy to enhance the catalytic properties of Pt-based ***,we report on surface engineering Ni-Pt nanoalloys with a facile method by varying the Ni doping concentration and oleylamine/oleicacid *** alloy-composition,exposed facet condition,and surface lattice strain are,thereby manipulated to optimize the catalytic efficiency of such nanoalloys for methanol oxidation reaction(MOR).Exemplary nanoalloys including Ni_(0.69)Pt_(0.31)truncated octahedrons,Ni_(0.45)Pt_(0.55)nanomultipods and Ni_(0.20)Pt_(0.80)nanoflowers are thoroughly characterized,with a commercial Pt/C catalyst as a common *** variations in MOR catalytic efficiency are significant:2.2 A/mgPt for Ni_(0.20)Pt_(0.80)nanoflowers,1.2 A/mgPt for Ni_(0.45)Pt_(0.55)nanomultipods,0.7 A/mgPt for Ni_(0.69)Pt_(0.31)truncated octahedrons,and 0.6 A/mgPt for the commercial Pt/C *** by density functional theory calculations,we correlate these observed catalysis-variations particularly to the intriguing presence of surface interplanar-strains,such as{111}facets with an interplanar-tensile-strain of 2.6%and{200}facets with an interplanar-tensile-strain of 3.5%,on the Ni_(0.20)Pt_(0.80)nanoflowers.

关键词： surface-strain high-index facets Ni-Pt alloy controllable synthesis electrocatalysis

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Gut microbiome composition can predict the response to nivolumab in advanced hepatocellular carcinoma patients

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World Journal of Gastroenterology 2021年第42期27卷 7340-7349页

作者： Min-Woo Chung Moon-Ju Kim Eun Jeong Won Yu Jeong Lee Yong-woon Yun Sung Bum Cho Young-Eun Joo Jun-Eul Hwang Woo Kyun Bae Ik-Joo Chung Myung Geun Shin jong Hee Shin Department of Internal Medicine Chonnam National University Hospital and College of MedicineHwasun 58128Jeollanam-doSouth Korea Department of Parasitology and Tropical Medicine Chonnam National University Medical SchoolHwasun 58128Jeollanam-doSouth Korea Department of Laboratory Medicine Chonnam National University Hwasun HospitalHwasun 58128Jeollanam-doSouth Korea Department of Preventive Medicine Chonnam National University Medical SchoolHwasun-eupHwasun 58128Jeollanam-doSouth Korea Department of Laboratory Medicine Chonnam National University HospitalGwangju 61469South Korea

BACKGROUND Immunotherapy has revolutionized the clinical outcomes of intractable cancer *** is known about the intestinal nonpathogenic bacterial composition of hepatocellular carcinoma(HCC)patients treated by *** To determine whether there is a correlation between gut bacterial composition and prognosis in HCC *** From September 2019 to March 2020,we prospectively collected fecal samples and examined the gut microbiome of 8 advanced HCC patients treated with nivolumab as a second-or third-line systemic *** samples were collected before the start of *** samples of patients with progression during treatment were collected at the time of progression,and fecal samples of patients who showed good response to nivolumab were collected after 5-7 mo as *** data from 16S ribosomal RNA sequencing were analyzed using CLC Genomics *** data were analyzed according to therapeutic *** All 8 patients were male,of which 6 had underlying chronic hepatitis B.A higher Shannon index was found in the responders than in the non-responders after nivolumab therapy(P=0.036).The unweighted beta diversity analysis also showed that the overall bacterial community structure and phylogenetic diversity were clearly distinguished according to therapeutic *** was no significant difference in the diversity or composition of the patient gut microbiome according to the immunotherapy *** taxa specific to therapeutic response were designated as follows:Dialister pneumosintes,Escherichia coli,Lactobacillus reteri,Streptococcus mutans,Enterococcus faecium,Streptococcus gordonii,Veillonella atypica,Granulicatella sp.,and Trchuris trichiura for the nonresponders;Citrobacter freundii,Azospirillum *** Enterococcus durans for the *** note,a skewed Firmicutes/Bacteroidetes ratio and a low Prevotella/Bacteroides ratio can serve as predictive markers of non-response,wh

关键词： Microbiome Nivolumab Firmicutes/Bacteroidetes ratio Prevotella/Bacteroides ratio Hepatocellular carcinoma Prognosis

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Improved formaldehyde gas sensing properties of well-controlled Au nanoparticle-decorated In2O3 nanofibers integrated on low power MEMS platform

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Journal of Materials Science & Technology 2020年第3期38卷 56-63页

作者： Dongha Im Donghyun Kim Dasol Jeong woon Ik Park Myoungpyo Chun Joon-Shik Park Hyunjung Kim Hyunsung Jung Nano Materials&Nano Technology Center Korea Institute of Ceramic Engineering&TechnologyJinju 52851Republic of Korea Department of Mineral Resources and Energy Engineering Chonbuk National UniversityJeonju 54896Republic of Korea Smart Sensor Research Center Korea Electronic Technology InstituteSeongnam 13509Republic of Korea

Approaches for the fabrication of a low power-operable formaldehyde(HCHO)gas sensor with high sensitivity and selectivity were performed by the utilization of an effective micro-structured platform with a micro-heater to reach high temperature with low heating power as well as by the integration of indium oxide(In2O3)nanofibers decorated with well-dispersed Au nanoparticles as a sensing *** In2O3 nanofibers with the large specific surface area were prepared by the electrospinning following by calcination *** nanoparticles with the well-controlled size as a catalyst were synthesized on the surface of In2O3 *** Au-decorated In2O3 nanofibers were reliably integrated as sensing materials on the bridge-type micro-platform including micro-heaters and *** micro-platform designed to maintain high temperature with low power consumption was fabricated by a microelectromechanical system(MEMS)*** micro-platform gas sensor consisting with Au-In2O3 nanofibers were fabricated effectively to detect HCHO gases with high sensitivity and *** HCHO gas sensing behaviors were schematically studied as a function of the gas concentration,the size of the adsorbed Au nanoparticles,the applied power to raise the temperature of a sensing part and the kind of target gases.

关键词： Gold nanoparticle In2O3 nanofiber Formaldehyde Gas sensor Low power Micro-platform

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Patients with culture negative pyogenic liver abscess have the same outcomes compared to those withKlebsiella pneumoniae pyogenic liver abscess

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Hepatobiliary & Pancreatic Diseases International 2016年第5期15卷 504-511页

作者： Vishal G Shelat Qiao Wang Clement LK Chia Zhongkai Wang Jee Keem Low Winston WL woon Department of General Surgery Tan Tock Seng Hospital Singapore 308433 Singapore Ministry of Health Holdings Pte Ltd. Singapore 099253 Singapore

BACKGROUND: Etiologic organism is not frequently isolated despite multiple blood and lfuid cultures during management of pyogenic liver abscess (PLA). Such culture negative pyogen-ic liver abscess (CNPLA) is routinely managed by antibiotics targeted toKlebsiella pneumoniae. In this study, we evaluated the outcomes of such clinical practice. METHODS: All the patients with CNPLA andKlebsiella pneu-moniaePLA (KPPLA) admitted from January 2003 to Decem-ber 2011 were included in the study. A retrospective review of medical records was performed and demographic, clinical and outcome data were collected. RESULTS: A total of 528 patients were treated as CNPLA or KPPLA over the study period. CNPLA presented more com-monly with abdominal pain (P=0.024). KPPLA was more com-mon in older age (P=0.029) and was associated with thrombo-cytopenia (P=0.001), elevated creatinine (P=0.002), bilirubin (P=0.001), alanine aminotransferase (P=0.006) and C-reactive protein level (P=0.036). CNPLA patients tend to have anemia (P=0.015) and smaller abscess (P=0.008). There was no differ-ence in hospital stay (15.7 vs 16.8 days) or mortality (14.0% vs 11.0%). No patients required surgical drainage after initiation of medical therapy. CONCLUSION: Despite demographic and clinical differences between CNPLA and KPPLA, overall outcomes are not different.

关键词： culture negative Klebsiella pneumoniae pyogenic liver abscess

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Substitute of Expensive Pt with Improved Electrocatalytic Performance and Higher Resistance to CO Poisoning for Methanol Oxidation: the Case of Synergistic Pt-Co_3O_4 Nanocomposite

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Nano-Micro Letters 2013年第4期5卷 296-302页

作者： Hongxiao Zhao Zhi Zheng Jing Li Huimin Jia Ka-wai Wong Yidong Zhang woon Ming Lau Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province Institute of Surface Micro and Nano Materials Xuchang University Chengdu Green Energy and Green Manufacturing R&D Center

In this paper, Pt-Co_3O_4 nanocomposite was synthesized by a sol gel process combined with electrodeposition method. Its electrocatalytic activity towards methanol oxidation was investigated at room temperature using cyclic voltammetry(CV), electrochemical impedance spectroscopy(EIS) and current density time curve. It is found that the resultant Pt-Co_3O_4 catalysts with minute amount of Pt exhibite attractive electrocatalytic activity for methanol oxidation reaction(MOR) but with a high resistance CO poisoning due to the synergistic effects from Pt and Co_3O_4. Together with the low manufacturing cost of Co_3O_4, the reported nanostructured Pt-Co_3O_4 catalyst is expected to be a promising electrode material for direct methanol fuel cells(DMFC).

关键词： Pt-Co3O4 nanocomposite MOR Electrocatalytic activity

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Taxonomic revisionofthegenus Lactarius(Russulales,Basidiomycota)in Korea

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Fungal Diversity 2019年第2期95卷 275-335页

作者： Hyun Lee Komsit Wissitrassameewong Myung Soo Park Annemieke Verbeken John Eimes Young woon Lim School of Biological Sciences and Institute of Microbiology Seoul National University1 Gwanak-roGwanak-guSeoul 08826Korea Department of Biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium University College Sungkyunkwan University2066 SeoburoJangan-guSuwon 16419Korea

The genus Lactarius Pers.(Russulales)is a cosmopolitan group of Basidiomycota that forms ectomycorrhizal relationships primarily with both deciduous and coniferous *** the genus has been well-studied in Europe and North America,only fragmentary researches have been carried out on Asian *** particular,the distribution of Lactarius species in South Korea is poorly understood due to insufficient morphological descriptions and a lack of DNA sequence *** addition,the misuse of European and North American names has added to confusion regarding the taxonomy of Asian Lactarius *** this study,the diversity of Lactarius in South Korea was evaluated by employing both morphological and phylogenetic approaches.A multi-locus phylogenetic analysis of 729 Lactarius specimens collected between 1960 and 2017 was performed using the internal transcribed spacer(ITS)region,partial nuclear ribosomal large subunit(nrLSU),partial second largest subunit of RNA polymerase II(rpb2),and minichromosome maintenance complex component 7(mcm7).49 Lactarius species were identified in three Lactarius subgenera:***(17 spp.),***(22 spp.),and ***(10 spp.).Among them,28 Lactarius species were identified as new to science,while just 17 were previously described Lactarius *** of the taxa remain un-named due to paucity of materials.A key to Korean Lactarius species,molecular phylogenies,a summary of diversity,and detailed description are provided.

关键词： Intercontinental conspecificity mcm7 Milkcaps Multi-locus phylogeny Species delimitation

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Inferring community properties of benthic macroinvertebrates in streams using Shannon index and exergy

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Frontiers of Earth Science 2014年第1期8卷 44-57页

作者： Tuyen Van NGUYEN woon-Seok CHO Hungsoo KIM Il Hyo JUNG YongKuk KIM Tae-Soo CHON Department of Mathematics Pusan National University Busan 609-735 Korea Department of Biological Sciences Pusan National University Busan 609-735 Korea DSPENALO National Robotics Research Center Pusan National University Busan 609-735 Korea Department of Mathematics Kyungpook National University Daegu 702-701 Korea

Definition of ecological integrity based on community analysis has long been a critical issue in risk assessment for sustainable ecosystem management. In this work, two indices （i.e., Shannon index and exergy） were selected for the analysis of community properties of benthic macroinvertebrate community in streams in Korea. For this purpose, the means and variances of both indices were analyzed. The results found an extra scope of structural and functional properties in communities in response to environmental variabilities and anthropogenic disturbances. The combination of these two parameters （four indices） was feasible in identification of disturbance agents （e.g., industrial pollution or organic pollution） and specifying states of communities. The four-aforemen- tioned parameters （means and variances of Shannon index and exergy） were further used as input data in a self- organizing map for the characterization of water quality. Our results suggested that Shannon index and exergy in combination could be utilized as a suitable reference system and would be an efficient tool for assessment of the health of aquatic ecosystems exposed to environmental disturbances.

关键词： benthic macroinvertebrates ecological integ-rity anthropogenic pollution self-organizing map

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Development of a skill assessment tool for the Korea operational oceanographic system

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Acta Oceanologica Sinica 2013年第9期32卷 74-81页

作者： CHO Kyoung-Ho CHOI Jin-Yong JEONG Sang-Hun CHOI Jung-woon KWON Jae-Il PARK Kwang-Soon Coastal Disaster Research Center Korea Institute of Ocean Science and Technology

A standard skill assessment （SA） tool was developed and implemented to evaluate the performance of op- erational forecast models in the Korea operational oceanographic system. The SA tool provided a robust way to assess model skill in the system by comparing predictions and observations, and involved the com- putation of multiple skill metrics including correlation and error skills. User- and system-based acceptance criteria of skill metrics were applied to determine whether predictions were acceptable for the system. To achieve this, the tool produced a time series comparison plot, a skill score table, and an advanced sum- marized diagram to effectively demonstrate the multiple skill scores. Moreover, the SA was conducted to evaluate both atmospheric and hydrodynamic forecast variables. For the atmospheric variables, acceptable error criteria were preferable to acceptable correlation criteria over short timescales, since the mean square error overwhelmed the observation variance. Conversely, for the hydrodynamic variables, acceptable root mean square percentage error （e.g., perms） criteria were preferable to acceptable error （e.g., erms） criteria owing to the spatially variable tidal intensity around the Korean Peninsula. Furthermore, the SA indicated that predetermined acceptance error criteria were appropriate to satisfy a target central frequency （fc） for which errors fell within the specified limits （i.e., the .fc equals 70%）.

关键词： skill assessment tool operational forecast system Korea operational oceanographic system

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