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AN EXPERIMENTAL OBSERVATION OF A SOLITARY WAVE IMPINGE-MENT,RUN-UP AND OVERTOPPING ON A SEAWALL

Journal of Hydrodynamics 2012年第1期24卷 76-85页

作者： LIN Ting-Chieh hwang kao-shu HSIAO Shih-Chun YANG Ray-Yeng Tainan Hydraulics Laboratory National Cheng Kung UniversityTainan 701 Department of Hydraulic and Ocean Engineering National Cheng Kung UniversityTainan 701 Tainan Hydraulics Laboratory and Department of Hydraulic and Ocean Engineering National Cheng Kung UniversityTainan 701

A sequence of laboratory experiments using solitary waves was performed to model the effect of leading form of three types of tsunamis（a bore,an impinging wave and an overtopping wave）on a seawall on a sloping *** wave evolution process,impinging pressure along the seawall surface,total overtopping discharge behind the seawall and the maximum run-up height on the rear slope were measured and *** data were employed to re-examine relevant empirical formulae in the *** effect of the presence of the seawall in reducing maximum run-up height using the present setup was briefly *** present data can be used for calibrating numerical and mathematical models.

关键词： solitary wave tsunami wave force run-up overtopping

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Cryptanalysis and improvement of controlled secure direct communication

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Chinese Physics B 2013年第6期22卷 203-205页

作者： kao Shih-Hung hwang Tzonelih National Cheng Kung University Institute of Computer Science and Information Engineering

This paper points out that, due to a flaw in the sender＇s encoding, the receiver in Gao et al.＇s controlled quantum secret direct communication （CQSDC） protocol [Chin. Phys. 14 （2005）, No. 5, p. 893] can reveal ... 详细信息

关键词： quantum cryptography quantum communication

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Low-dose testosterone treatment decreases oxidative damage in TM3 Leydig cells

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Asian Journal of Andrology 2011年第3期13卷 432-437,512页

作者： Thomas IS hwang Tien-Ling Liao Ji-Fan Lin Yi-Chia Lin shu-Yu Lee Yen-Chun Lai shu-Huei kao Department of Urology Taipei Medical University Taipei Taiwan China Department of Urology School of Medicine Fu-Jen Catholic University Taipei Taiwan China Division of Urology Department of Surgery Shin Kong Wu Ho-Su Memorial Hospital Taipei Taiwan China School of Medical Laboratory Science and Biotechnology Taipei Medical University Taipei Taiwan China Central Laboratory Shin Kong Wu Ho-Su Memorial Hospital Taipei Taiwan China

Testosterone replacement therapy has benefits for aging men and those with hypogonadism. However, the effects of exogenous testosterone on Leydig cells are still unclear and need to be clarified. In this report, we demonstrate that testosterone supplementation can reduce oxidative damage in Leydig cells. The TM3 Leydig cell line was used as an in vitrocell model in this study. Cytoprotective effects were identified with 100-nmol l-1 testosterone treatment, but cytotoxic effects were found with ≥ 500-nmol l-1 testosterone supplementation. Significantly reduced reactive oxygen species （ROS） generation, lipid peroxide contents and hypoxia induction factor （HIF）-lα stabilization and activation were found with lO0-nmol 1-1 testosterone treatment. There was a 1.72-fold increase in ROS generation in the 500-nmol l-1 compared to the lO0-nmol l-1 testosterone treatment. A 1.58-fold increase in steroidogenic acute regulatory protein （STAR） expression was found in 50-nmol l-1 testosterone-treated cells （P〈0.01）. Chemically induced hypoxia was attenuated by testosterone supplementation. Leydig cells treated with low-dose testosterone supplementation showed cytoprotection by decreasing ROS and lipid peroxides, increasing StAR expression and relieving hypoxia stress as demonstrated by HIF-1α stabilization. Increased oxidative damage was found with ≥ 500-nmol l-1 testosterone manipulation. The mechanism governing the differential dose effects of testosterone on Leydig cells needs further investigation in order to shed light on testosterone replacement therapy.

关键词： Leydig cells oxidative damage reactive oxygen species testosterone

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Clinical features of human intestinal capillariasis in Taiwan

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World Journal of Gastroenterology 2004年第16期10卷 2391-2393页

作者： Ming-Jong Bair kao-Pin hwang Tsang-EnWang Tai-CherngLiou Shee-ChanLin Chin-Roakao Tao-Yeuan Wang Kwok-Kuen Pang Department of Gastroenterology Mackay Memorial HospitalTaitung BranchTaiwanChina Department of Pediatrics Kaohsiung Medical CollegeTaipeiChina Department of Gastroenterology Mackay Memorial HospitalTaipeiChina Department of Pathology Mackay Memorial HospitalTaipeiChina Department of Radiology Mackay Memorial HospitalTaitung BranchTaiwanChina

Human intestinal capillariasis is a rare parasitosis that was first recognized in the Philippines in the 1960 s. Parasitosis is a life threatening disease and has been reported from Thailand, Japan, South of Taiwan (kaoh-Siung), Korea,Iran Egypt, Italy and Spain. Its clinical symptoms are characterized by chronic diarrhea, abdominal pain,borborygmus, marked weight loss, protein and electrolyte loss and cachexia. Capillariasis may be fatal if early treatment is not given. We reported 14 cases living in rural areas of Taiwan. Three cases had histories of travelling to Thailand. They might have been infected in Thailand while stayed there. Two cases had the diet of raw freshwater fish before. Three cases received emergency laparotomy due to peritonitis and two cases were found of enteritis cystica profunda. According to the route of transmission,freshwater and brackish-water fish may act as the intermediate host of the parasite. The most simple and convenient method of diagnosing capillariasis is stool examination. Two cases were diagnosed by histology. Mebendazole or albendezole 200 mg orally twice a day for 20-30 d is the treatment ef choice. All the patients were cured, and relapses were not obsetbed within 12 mo,

关键词：临床特征毛细线虫病肠内疾病寄生虫台湾省中国

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Adaptive Linearization Control Based on Reinforcement Learning

Adaptive Linearization Control Based on Reinforcement Learni...

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2002年IEEE十区计算机、通信、控制和电机工程会议

作者： kao-Shing hwang Jeng-Yih Chiou Electrical Engineer Department National Chung Cheng University 160 San-Hsing Ming-Hsiung Chia-Yi Taiwan China Electrical Engineer Department National Chung Cheng University 160 San-Hsing Ming-Hsiung Chia-Yi Taiwan China

Based on the feedback linearization theory,this paper demonstrates how a reinforcement learningscheme, adopted to construct an artificial neural networks(ANNs), can linearize a nonlinear system more effectivelyand cancel the effect of nonlinearity of a plant. Theproposed Reinforcement Linearization Learning System(RLLS) consists of two sub-systems: one is a long-termpolicy selector, Evaluation Predictor (EP) element, and theother is a short-term action selector, consisting ofLinearizing Control (LC) and Reinforce Predictor (RP)elements. In addition, a affine linear reference modelplays a role of the environment (instructor), whichprovides the reinforcement signal in the linearizingprocess. Simulation results demonstrate that the proposedscheme has the better performance of reliability androbustness of the controlled structure than conventionalANNs schemes.

关键词： Adaptive Linearization Control Based on Reinforcement Learning

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基于自注意力机制和策略映射重组的多智能体强化学习算法

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计算机学报 2022年第9期45卷 1842-1858页

作者：李静晨史豪斌黄国胜西北工业大学计算机学院西安710072 “高雄中山大学”电机系中国高雄0008

多智能体强化学习(Multi-Agent Reinforcement Learning,MARL)在群体控制领域中被广泛应用,但由于单个智能体的马尔可夫决策模型被破坏,现有的MARL算法难以学习到最优策略,且训练中智能体的随机性会导致策略不稳定.本文从状态空间到行... 详细信息

多智能体强化学习(Multi-Agent Reinforcement Learning,MARL)在群体控制领域中被广泛应用,但由于单个智能体的马尔可夫决策模型被破坏,现有的MARL算法难以学习到最优策略,且训练中智能体的随机性会导致策略不稳定.本文从状态空间到行为空间的映射出发,研究同构多智能体系统的耦合转换,以提高策略的先进性及稳定性.首先,我们调查了同构智能体行为空间的重组,打破智能体与策略对应的固定思维,通过构建抽象智能体将智能体之间的耦合转换为不同智能体行为空间同一维度的耦合,以提高策略网络的训练效率和稳定.随后,在重组策略映射的基础上,我们从序列决策的角度出发,为抽象智能体的策略网络和评估网络分别设计自注意力模块,编码并稀疏化智能体的状态信息.重组后的状态信息经过自注意力编码后,能显示地解释智能体的决策行为.本文在三个常用的多智能体任务上对所提出方法的有效性进行了全面的验证和分析,实验结果表明,在集中奖励的情况下,本文所提出的方法能够学到比基线方法更为先进的策略,平均回报提高了20%,且训练过程与训练结果的稳定性提高了50%以上.多个对应的消融实验也分别验证了抽象智能体与自注意力模块的有效性,进一步为我们的结论提供支持.

关键词：多智能体系统多智能体强化学习深度强化学习注意力机制

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Application of artificial intelligence-driven endoscopic screening and diagnosis of gastric cancer

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World Journal of Gastroenterology 2021年第22期27卷 2979-2993页

作者： Yu-Jer Hsiao Yuan-Chih Wen Wei-Yi Lai Yi-Ying Lin Yi-Ping Yang Yueh Chien Aliaksandr A Yarmishyn De-Kuang hwang Tai-Chi Lin Yun-Chia Chang Ting-Yi Lin kao-Jung Chang Shih-Hwa Chiou Ying-Chun Jheng Department of Medical Research Taipei Veterans General HospitalTaipei 112201Taiwan School of Medicine National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Department of Medical Education Taipei Veterans General HospitalTaipei 112201Taiwan Institute of Pharmacology National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Department of Internal Medicine Taipei Veterans General HospitalTaipei 112201Taiwan Critical Center Taipei Veterans General HospitalTaipei 112201Taiwan Department of Ophthalmology Taipei Veterans General HospitalTaipei 112201Taiwan Institute of Clinical Medicine National Yang-Ming Chiao Tung UniversityTaipei 112201Taiwan Department of Medicine Kaohsiung Medical UniversityKaohsiung 80708Taiwan Institute of Clinical Medicine National Yang-Ming Chiao Tung UniversityTaipei 112304Taiwan Big Data Center Taipei Veterans General HospitalTaipei 112201Taiwan

The landscape of gastrointestinal endoscopy continues to evolve as new technologies and techniques become *** advent of image-enhanced and magnifying endoscopies has highlighted the step toward perfecting endoscopic screening and diagnosis of gastric ***,with the development of convolutional neural network,artificial intelligence(AI)has made unprecedented breakthroughs in medical imaging,including the ongoing trials of computer-aided detection of colorectal polyps and gastrointestinal *** the past demi-decade,applications of AI systems in gastric cancer have also *** AI’s efficient computational power and learning capacities,endoscopists can improve their diagnostic accuracies and avoid the missing or mischaracterization of gastric neoplastic *** far,several AI systems that incorporated both traditional and novel endoscopy technologies have been developed for various purposes,with most systems achieving an accuracy of more than 80%.However,their feasibility,effectiveness,and safety in clinical practice remain to be seen as there have been no clinical trials ***,AI-assisted endoscopies shed light on more accurate and sensitive ways for early detection,treatment guidance and prognosis prediction of gastric *** review summarizes the current status of various AI applications in gastric cancer and pinpoints directions for future research and clinical practice implementation from a clinical perspective.

关键词： Artificial intelligence Diagnostic Therapeutic Endoscopy Gastric cancer Gastritis

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