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地方高校参与高质量乡村振兴的多案例研究

北京社会科学 2024年第4期 76-89页

作者：黄巨臣霍胜君兰州大学高等教育研究院

基于组织社会学视域,构建“组织—环境”分析框架,以典型个案为例,并将它们做类型化划分,进而探究不同区域地方高校参与乡村振兴的样态。研究发现,在特定情况下,以文化开发型参与为主的高校受到历史传统环境制约,生态建设型易被环境保... 详细信息

基于组织社会学视域,构建“组织—环境”分析框架,以典型个案为例,并将它们做类型化划分,进而探究不同区域地方高校参与乡村振兴的样态。研究发现,在特定情况下,以文化开发型参与为主的高校受到历史传统环境制约,生态建设型易被环境保护与开发政策牵引,而产业发展型则依赖于利用信息技术环境;拥有厚重的历史传统底蕴、良好的自然风光环境和规模化的农业生产分别是文化开发型、生态建设型与产业发展型适用推广的前提条件;三种类型的地方高校参与模式虽体现出了不同任务导向和组织优势条件下的差异化策略及其效果,但它们却一致遵循“通过发展促进农民增收”的共同富裕逻辑。

关键词：地方高校乡村振兴高质量发展组织社会学共同富裕

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数字化平台如何助推职业教育人才培养——来自德国的经验与启示

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高等职业教育探索 2024年第1期23卷 10-15,23页

作者：黄巨臣霍胜君泉州职业技术大学福建泉州362000 兰州大学甘肃兰州730000

从德国职业教育数字化平台建设的多重动因入手,结合具体的国家平台案例分析其在助推人才培养方面的做法与特色,包括学生主体的目标定位、打破界限的业务内容和政府监督的组织保障。进而结合我国职业教育人才培养的实际情况,提出应构建... 详细信息

从德国职业教育数字化平台建设的多重动因入手,结合具体的国家平台案例分析其在助推人才培养方面的做法与特色,包括学生主体的目标定位、打破界限的业务内容和政府监督的组织保障。进而结合我国职业教育人才培养的实际情况,提出应构建数字化职业教育学习新范式,开发多样性职业教育教学新内容和打造国家级职业教育管理新路径,培养敬业乐群,知技并重的人才,保持在全球竞争中的有利地位。

关键词：德国数字化平台职业教育人才培养

营养包干预对婴幼儿唾液中免疫球蛋白A水平影响的研究

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营养学报 2024年第1期46卷 13-17页

作者：刘婷婷冯静孙静霍军生程家丽宫照龙中国疾病预防控制中心营养与健康所北京100050

目的探讨营养包作为6~24月龄婴幼儿辅食补充剂,对婴幼儿唾液中分泌型免疫球蛋白A含量的影响。方法选择营养包干预地区和其临近未干预地区的婴幼儿,进行早期儿童营养干预与非干预人群营养健康状况的长期队列观察。干预组婴幼儿在6~24月... 详细信息

目的探讨营养包作为6~24月龄婴幼儿辅食补充剂,对婴幼儿唾液中分泌型免疫球蛋白A含量的影响。方法选择营养包干预地区和其临近未干预地区的婴幼儿,进行早期儿童营养干预与非干预人群营养健康状况的长期队列观察。干预组婴幼儿在6~24月龄期间每日辅食中添加一袋营养包,对照组不服用营养包,此外同时为对照组和干预组提供科学健康喂养指导。在2018年至2020年连续3年的监测中,收集婴幼儿唾液并检测其唾液中免疫球蛋白A含量,并对婴幼儿唾液中免疫球蛋白A的含量变化情况进行比较和分析。结果本研究婴幼儿唾液中的免疫球蛋白A含量随着月龄的增加呈增加的趋势,干预组和对照组婴幼儿在2018年基线阶段的免疫球蛋白A含量没有显著性差异。2019年和2020年干预组婴幼儿唾液中的免疫球蛋白A含量均高于地域邻近的对照组,差异有统计学意义(P<0.05)。结论营养包干预能够提升婴幼儿唾液中免疫球蛋白A水平,增强婴幼儿免疫力。

关键词：婴幼儿营养包唾液免疫球蛋白A

Triclosan-induced Oxidative Stress Injury and Apoptosis by Regulating the PI3K/Akt/Caspase-3 Signaling Pathway in Human Renal Glomerular Endothelial Cells

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Biomedical and Environmental Sciences 2022年第6期35卷 547-551页

作者： MA Yan CHEN Chen WANG Jing Bo CHENG Jia Li SHEN Shi CHEN Xi huo jun sheng Key Laboratory of Trace Element Nutrition National Institute for Nutrition and HealthChinese Center for Disease Control and PreventionBeijing 100050China

Triclosan(TCS)is widely used in personal-care products because of its bactericidal and antibacterial ***,TCS and its toxic byproducts have been detected in aquatic environments,animals,and plants *** is a common phenolic environmental endocrine disruptor,and TCS in the environment enters the body mainly through diet and *** of the absorbed TCS is metabolized by the human kidneys and is eliminated in the urine[1].Some epidemiological studies have suggested a positive correlation between the TCS exposure level in urine and albumin(a biomarker of renal function),which could cause renal dysfunction[2].However,the potential effects of TCS on the mammalian kidney and its mechanisms are currently ***,we initiated an in vitro trial to study the molecular mechanism of cytotoxicity of TCS to glomeruli.

关键词： PI3K/Akt urine Apoptosis

营养包与6~24月龄婴幼儿Hb水平和贫血率的阈值效应关系研究

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中国食物与营养 2024年第1期30卷 44-47页

作者：冯静刘婷婷霍军生卓勤宫照龙中国疾病预防控制中心营养与健康所/国家卫生健康委员会微量元素与营养重点实验室北京100050

目的:探讨营养包(Ying Yang Bao,YYB)服用时长和频率与6~24月龄婴幼儿血红蛋白(Hemoglobin,Hb)水平和贫血率之间的阈值效应关系。方法:研究数据来自于早期儿童营养包干预长期营养健康作用评估项目。采用t检验和卡方检验比较连续变量和... 详细信息

目的:探讨营养包(Ying Yang Bao,YYB)服用时长和频率与6~24月龄婴幼儿血红蛋白(Hemoglobin,Hb)水平和贫血率之间的阈值效应关系。方法:研究数据来自于早期儿童营养包干预长期营养健康作用评估项目。采用t检验和卡方检验比较连续变量和分类变量的组间差异。采用限制性立方样条回归检验YYB服用时长和频率与儿童血红蛋白(Hb)水平和贫血率之间的非线性趋势,探索可能存在的阈值效应关系。结果:YYB服用时长与Hb水平和贫血率的非线性趋势检验P值分别为0.665和0.211,服用频率与Hb水平和贫血率的非线性趋势检验P值分别为0.110和0.157。YYB服用时长达到8.68个月时,Hb水平变化的斜率β=0,贫血发生风险的OR=1;YYB服用频率达5.6袋/周时,Hb水平变化的斜率β=0,服用频率达4.6袋/周时,贫血发生风险的OR=1。结论:YYB服用时长和频率与6~24月龄婴幼儿Hb水平和贫血率之间存在线性关联;改善Hb水平和贫血率的最低有效时长约为8.6个月,最低有效频率约为5~6袋/周。

关键词：营养包 Hb水平和贫血限制性立方样条回归阈值效应关系

Optimization of Three-Dimensional Culture Conditions of HepG2 Cells with Response Surface Methodology Based on the VitroGel System

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Biomedical and Environmental Sciences 2022年第8期35卷 688-698页

作者： WANG Jing Bo QIN Wen YANG Zhuo SHEN Shi MA Yan WANG Li Yuan Zhuo Qin GONG Zhao Long huo jun sheng CHEN Chen National Institute for Nutrition and Health Chinese Centre for Disease Control and PreventionBeijing 100050China

Objective This study optimizes three-dimensional(3D) culture conditions of HepG2 using response surface methodology(RSM) based on the VitroGel system to facilitate the cell model in vitro for liver *** HepG2 cell was 3D cultured on the VitroGel *** viability was detected using Cell Counting Kit-8(CCK-8) assay of HepG2 lived cell *** proliferation of HepG2 cell and clustering performance was measured via fluorescence staining *** concentration in the culture medium supernatant as an index of HepG2 cell biological function was measured with ELISA *** factor tests were conducted with three key factors:inoculated cell concentration,cultured time,and dilution degree of the *** preliminary results of independent factor tests were used to determine the levels of factors for *** The selected optimal culture conditions are as follows:concentration of inoculated cells was4.44 × 10^(5)/mL,culture time was 4.86 days,and hydrogel dilution degree was 1:*** result shows that under optimal conditions,the predicted optical density(OD) value of cell viability was 3.10 and measured 2.978 with a relative error of 3.94%.Conclusion This study serves as a reference for the 3D HepG2 culture and constructs liver tissues in ***,it provides the foundation for repeated dose high-throughput toxicity studies and other scientific research work.

关键词： Response surface methodology The three-dimensional culture Hydrogel

Integral precession calibration method of PIGA on linear vibration table

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Chinese Journal of Aeronautics 2024年第3期37卷 219-236页

作者： Chuang SUN Shun-qing REN jun-wei CAO Ru huo Department of Automation Tsinghua UniversityBeijing 100084China School of Astronautics Harbin Institute of TechnologyHarbin 150001China Beijing National Research Center for Information Science and Technology Tsinghua UniversityBeijing 100084China Faculty of Information technology Beijing University of TechnologyBeijing 100124China

Linear vibration table can provide harmonic accelerations to excite the nonlinear error terms of Pendulous Integrating Gyro Accelerometer(PIGA).Integral precession calibration method is proposed to calibrate PIGA on a linear vibration table in this *** on the precise expressions of PIGA’s inputs,the error calibration model of PIGA is *** angular velocity errors of PIGA are suppressed by integer periodic precession and the errors caused by non-integer periods vibrating are *** complete calibration process,including planning,preparation,PIGA testing,and coefficient identification,is designed to optimize the test operations and evaluate the calibration *** effect of the main errors on calibration uncertainty is analyzed and the relative sensitivity function is proposed to further optimize the test *** and simulation results verify that the proposed 10-position calibration method can improve calibration uncertainties after compensating for the related *** order of calibration uncertainties of the second-and third-order coefficients are decreased to 10^(-8)(rad.s^(-1))/g^(2)and 10^(-8)(rad.s^(-1))/g3,*** with the other two classical calibration methods,the calibration uncertainties of PIGA’s nonlinear error coefficients can be effectively reduced and the proportional residual errors are decreased less than 3×10-6(rad.s^(-1))/g by using the proposed calibration method.

关键词： PIGA Linear vibration table Vibration measurement Calibration Error analysis Uncertainty analysis

Prediction of liquid circulation flow rate in RH degasser:improvement of decarburization at low atmospheric pressure

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Journal of Iron and Steel Research(International) 2024年第7期31卷 1661-1667页

作者： Gu-jun Chen sheng-ping He College of Materials Science and Engineering Yangtze Normal UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

The two-fluid model coupled with population balance model was used for simulating the gas-liquid flow in the Ruhrstahl-Heraeus(RH)*** predicted circulation flow rate was compared with that measured from a water model experiment to validate the mathematical ***,influence of snorkel immersion depth on liquid circulation flow rate was numerically investigated under an atmospheric pressure of 101 and 84 kPa,*** result indicates that the circulation flow rate of the RH degasser in the high-altitude area was severely reduced because of the decrease in atmospheric ***,increasing the snorkel immersion depth from 0.5 to 0.7 m can compensate for the decrease in atmospheric *** test result indicates that decarburization rate is significantly enhanced by increasing the snorkel immersion *** optimization,the percentage of heats with a final carbon content less than 0.002 wt.%is significantly increased from 22.0%to 96.4%.

关键词： RH degasser Two-fluid model Population balance model-Circulation flow rate Decarburization Snorkel immersion depth

Two New Cytotoxic Sesquiterpenoids from Eupatorium lindleyanum DC.

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Journal of Integrative Plant Biology 2006年第4期48卷 473-477页

作者： jun huo sheng-Ping Yang Jian Ding Jian-Min Yue State Key Laboratory of Drug Research Institute of Materia Medica Shanghai Institute for Biological Sciences the Chinese Academy of Sciences Shanghai 201203 China

Two new sesqulterpenold lactones, namely eupallnllides K and L, were isolated from Eupatorlum Ilndleyanum DC. Their structures were determined by spectral methods, Including 1 D-and 2D-NMR spectra. Cytotoxlc evaluatlon showed that eupallnlllde L exhibited potent cytotoxlclty against P-388 and A-549 tumor cell lines with IC50 values of 0.17 and 2.60 p, mol/L, respectively.

关键词： eupalinilides K and L Eupatorium lindleyanum sesquiterpenoid