检索结果-南通市图书馆

Functional Photoacoustic and Ultrasonic Assessment of Osteoporosis:A Clinical Feasibility Study

Biomedical Engineering Frontiers 2020年第1期1卷 35-49页

作者： Ting Feng Yunhao Zhu richard morris Kenneth m.Kozloff Xueding Wang Department of Biomedical Engineering University of Michigan Medical SchoolMI 48109USA IF LLCWI 53589USA Department of Orthopaedic Surgery University of Michigan Medical SchoolMI 48109USA Department of Radiology University of Michigan Medical SchoolMI 48109USA

Objective and Impact *** study the feasibility of combined functional photoacoustic(PA)and quantitative ultrasound(US)for diagnosis of osteoporosis in vivo based on the detection of chemical and microarchitecture(BmA)information in calcaneus *** available X-ray or US technologies for the diagnosis of osteoporosis do not report important parameters such as chemical information and *** unique advantages,including good sensitivity to molecular and metabolic properties,PA bone assessment techniques hold a great potential for clinical *** performing multiwavelength PA measurements,the chemical information in the human calcaneus bone,including mineral,lipid,oxygenated-hemoglobin,and deoxygenated-hemoglobin,were *** parallel,by performing PA spectrum analysis,the BmA as an important bone physical property was *** unpaired t-test and a two-way ANOVA test were conducted to compare the outcomes from the two subject *** PA measurement is capable of assessing the relative contents of several chemical components in the trabecular bone in vivo,including both minerals and organic materials such as oxygenated-hemoglobin,deoxygenated-hemoglobin,and lipid,which are relevant to metabolic activities and bone *** addition,PA measurements of BmA show good correlations(R^(2)up to 0.65)with *** the chemical and microarchitectural measurements from PA techniques can differentiate the two subject *** results from this initial clinical study suggest that PA techniques,by providing additional chemical and microarchitecture information relevant to bone health,may lead to accurate and early diagnosis,as well as sensitive monitoring of the treatment of osteoporosis.

关键词： diagnosis Clinical architectural

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of Aronia polyphenols on the physico-chemical properties of whey,soy,and pea protein isolate dispersions

引用

Food Production, Processing and Nutrition 2021年第1期3卷 391-405页

作者： mackenzie m.Hansen richard W.Hartel Yrjö H.Roos Food Technology School of Food and Nutritional SciencesUniversity College CorkCorkIreland Department of Food Science College of Agricultural and Life SciencesUniversity of WisconsinOffice A11Babcock Hall1605 Linden DriveMadisonWI 53706USA

Bioactive compounds including polyphenols(PP)have been observed to naturally form non-covalent complexation interactions with proteins under mild pH and temperature conditions,affecting protein structures and ***,addition of Aronia berry PP to liquid dispersions containing whey protein isolate(WPI)and sucrose was found to alter characteristics including viscosity,surface tension,and particle sizes,with changes being attributed to protein-PP *** this study we aimed to investigate whether Aronia PP would interact with soy and pea protein isolates(SPI and PPI,respectively)to a similar extent as with WPI in liquid protein-sucrose-PP *** hypothesized that formulations containing PPI(comprised of larger proteins)and hydrolyzed SPI(containing more carboxyl groups)may exhibit increased viscosities and decreased aggregate sizes due to enhanced protein-PP *** liquid dispersions of varied ratios of protein to sucrose contents,containing different protein isolates(WPI,SPI,and PPI),and varied Aronia PP concentrations were formulated,and physical properties were evaluated to elucidate the effects of PP *** addition altered physical characteristics differently depending on the protein isolate used,with changes attributed to protein-PP *** and PPI appeared to have higher propensities for PP interactions and exhibited more extensive shifts in physical properties than WPI *** findings may be useful for practical applications such as formulating products containing fruit and proteins to obtain desirable sensory attributes.

关键词： Whey protein Soy protein Pea protein Polyphenols Concentrated dispersions Physico-chemical properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In memoriam:*** ***

引用

International Soil and Water Conservation Research 2021年第4期9卷 485-489页

作者： Dennis C.Flanagan richard m.Cruse James L.Baker Paige Chyu USDA-Agricultural Research Service National Soil Erosion Research LaboratoryWest LafayetteINUSA Department of Agronomy Iowa State UniversityAmesIAUSA Department of Agricultural&Biosystems Engineering Iowa State UniversityAmesIAUSA International Research and Training Center on Erosion and Sedimentation BeijingChina

The soil erosion research and soil and water conservation global community lost a treasured member on November 20,2020,when *** matthew Laflen(Fig.1)*** one with a friendly welcoming smile,John had hundreds of friends,both personally and professionally throughout the *** article includes many of his professional and scientific contributions,and impacts from his research and outreach activities.

关键词： soil hundreds professional

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lower esophageal sphincter relaxation is impaired in older patients with dysphagia

引用

World Journal of Gastroenterology 2011年第10期17卷 1326-1331页

作者： Laura K Besanko Carly m Burgstad Reme mountifi eld Jane m Andrews richard Heddle Helen Checklin Robert JL Fraser Investigation and Procedures Unit Repatriation General Hospital Department of Gastroenterology and Hepatology Royal Adelaide Hospital Discipline of medicine University of Adelaide Adelaide 5000 South Australia Australia Department of medicine Flinders University of South Australia Bedford Park 5042 South Australia Australia

AIm: To characterize the effects of age on the mechanisms underlying the common condition of esophageal dysphagia in older patients, using detailed manometric analysis. mETHODS: A retrospective case-control audit was performed on 19 patients aged ≥ 80 years (mean age 85 ± 0.7 year) who underwent a manometric study for dysphagia (2004-2009). Data were compared with 19 younger dysphagic patients (32 ± 1.7 years). Detailed manometric analysis performed prospectively included basal lower esophageal sphincter pressure (BLESP), pre-swallow and nadir LESP, esophageal body pressures and peristaltic duration, during water swallows (5 mL) in right lateral (RL) and upright (UR) postures and with solids. Data are mean ± SE; a P-value mmHg; P mmHg vs 0.7 ± 0.6 mmHg, P mmHg vs 1.6 ± 0.5 mmHg, P = 0.01) with shorter relaxation after solids (7.9 ± 1.5 s vs 9.7 ± 0.4 s, P = 0.05). No age-related differences were seen in esophageal body pressures or peristalsis duration. CONCLUSION: Basal LES pressure is elevated and swallow-induced relaxation impaired in elderly dysphagic patients. Its contribution to dysphagia and the effects of healthy ageing require further investigation.

关键词： Dysphagia Elderly Esophageal motility Lower Esophageal Sphincter Aging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Twenty-first century climate change and submerged aquatic vegetation in a temperate estuary:the case of Chesapeake Bay

引用

Ecosystem Health and Sustainability 2017年第7期3卷 14-34页

作者： Thomas m.Arnold richard C.Zimmerman Katharina A.m.Engelhardt J.Court Stevenson Departments of Biology and Environmental Studies Dickinson CollegeCarlislePAUSA Department of Ocean Earth and Atmospheric SciencesOld Dominion UniversityNorfolkVAUSA Appalachian Laboratory University of Maryland Center for Environmental ScienceFrostburgMDUSA Horn Point Laboratory University of Maryland Center for Environmental ScienceCambridgeMDUSA

Introduction:The Chesapeake Bay was once renowned for expansive meadows of submerged aquatic vegetation(SAV).However,only 10%of the original meadows *** restoration effortswill be complicated by accelerating climate change,including physiological stressors such as a predicted mean temperature increase of 2-6℃and a 50-160%increase in CO_(2)***:As the Chesapeake Bay begins to exhibit characteristics of a subtropical estuary,summer heat waves will become more frequent and *** alone would eventually eliminate eelgrass(Zostera marina)from the *** will favor native heat-tolerant species such as widgeon grass(Ruppia maritima)while facilitating colonization by non-native seagrasses(e.g.,Halodule spp.).Intensifying human activity will also fuel coastal zone acidification and the resulting high CO_(2)/low pH conditions may benefit SAV via a“CO_(2)fertilization effect.”Discussion:Acidification is known to offset the effects of thermal stress and may have similar effects in estuaries,assuming water clarity is sufficient to support CO_(2)-stimulated photosynthesis and plants are not overgrown by ***,coastal zone acidification is variable,driven mostly by local biological processes that may or may not always counterbalance the effects of regional *** precarious equipoise between two forces-thermal stress and acidification-will be critically important because it may ultimately determine the fate of cool-water plants such as Zostera marina in the Chesapeake ***:The combined impacts of warming,coastal zone acidification,water clarity,and overgrowth of competing algae will determine the fate of SAV communities in rapidly changing temperate estuaries.

关键词： Submerged aquatic vegetation climate temperature coastal acidification Chesapeake Bay

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stigmatic exudate in the Annonaceae:Pollinator reward,pollen germination medium or extragynoecial compitum?

引用

Journal of Integrative Plant Biology 2017年第12期59卷 881-894页

作者： Jenny Y.Y.Lau Chun-Chiu Pang Lawrence Ramsden richard m.K.Saunders School of Biological Sciences the University of Hong KongPokfulam RoadHong KongChina

Although ＂dry-type＂ stigmas are widely re- garded as ancestral in angiosperms, the early-divergent family Annonaceae has copious stigmatic exudate. We evaluate three putative functions for this exudate： as a nutritive reward for pollinators; as a pollen germination medium; and as an extragynoecial compitum that enables pollen tube growth between carpels. Stigmatic exudate is fructose dominated （72.2%）, but with high levels of glucose and sucrose; the dominance of hexose sugars and the diversity of amino acids observed, including many that are essential for insects, support a nutritive role for pollinators. Sugar concentration in pre-receptive flowers is high （28.2%）, falling during the peak period of stigmatic receptivity （17.4%）, and then rising again toward the end of the pistillate phase （32.9%）. Pollen germination was highest in sugar concentrations 〈2%. Sugar concentrations during the peak pistillate phase therefore provide optimal osmolarity for pollen hydration and germination; subsequent changes in sugar concentration during anthesis reinforce protogyny （in which carpels mature before stamens）, enabling the retention of concentrated exudate into the staminate phase as a pollinator food reward without the possibility of pollen germination. Intercarpellary growth of pollen tubes was confirmed： the exudate therefore also functions as a suprastylar extragynoecial compitum, overcoming the limitations of apocarpy.

关键词： Stigmatic exudate in the Annonaceae pollen germination medium or extragynoecial compitum Pollinator reward

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Promoting axon regeneration in the central nervous system by increasing PI3-kinase signaling

引用

Neural Regeneration Research 2022年第6期17卷 1172-1182页

作者： Bart Nieuwenhuis richard Eva John van Geest Center for Brain Repair Department of Clinical NeurosciencesUniversity of CambridgeCambridgeUK

much research has focused on the PI3-kinase and PTEN signaling pathway with the aim to stimulate repair of the injured central nervous *** in the central nervous system fail to regenerate,meaning that injuries or diseases that cause loss of axonal connectivity have life-changing *** 2008,genetic deletion of PTEN was identified as a means of stimulating robust regeneration in the optic *** is a phosphatase that opposes the actions of PI3-kinase,a family of enzymes that function to generate the membrane phospholipid PIP_(3) from PIP_(2)(phosphatidylinositol(3,4,5)-trisphosphate from phosphatidylinositol(4,5)-bisphosphate).Deletion of PTEN therefore allows elevated signaling downstream of PI3-kinase,and was initially demonstrated to promote axon regeneration by signaling through *** recently,additional mechanisms have been identified that contribute to the neuron-intrinsic control of regenerative *** review describes neuronal signaling pathways downstream of PI3-kinase and PIP3,and considers them in relation to both developmental and regenerative axon *** briefly discuss the key neuron-intrinsic mechanisms that govern regenerative ability,and describe how these are affected by signaling through *** highlight the recent finding of a developmental decline in the generation of PIP_(3) as a key reason for regenerative failure,and summarize the studies that target an increase in signaling downstream of PI3-kinase to facilitate regeneration in the adult central nervous ***,we discuss obstacles that remain to be overcome in order to generate a robust strategy for repairing the injured central nervous system through manipulation of PI3-kinase signaling.

关键词： axon cytoskeleton axon regeneration axon transport cell signaling central nervous system growth cone neuroprotection PI3-kinase PI3K PTEN trafficking transcription translation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spatial and temporal analysis of beta diversity in the Barro Colorado Island forest dynamics plot, Panama

引用

Forest Ecosystems 2019年第1期6卷 76-86页

作者： Pierre Legendre richard Condit Département de sciences biologiques Université de Montréal Field museum of Natural History morton Arboretum

Background: Ecologists are interested in assessing the spatial and temporal variation in ecological surveys repeated over time. This paper compares the 1985 and 2015 surveys of the Barro Colorado Forest Dynamics plot(BCI), Panama,divided into 1250(20 m × 20 m) ***, spatial analysis: Total beta diversity was measured as the total variance of the Hellinger-transformed community data throughout the BCI plot. Total beta was partitioned into contributions of individual sites(LCBD indices), which were tested for significance and ***, spatial analysis: LCBD indices indicated the sites with exceptional community composition. In 1985,they were mostly found in the swamp habitat. In the 2015 survey, none of the swamp quadrats had significant *** happened to the tree community in the interval?methods, temporal analysis: The dissimilarity in community composition in each quadrat was measured between time 1(1985) and time 2(2015). Temporal Beta Indices(TBI) were computed from abundance and presence-absence data and tested for significance. TBI indices can be decomposed into B = species(or abundances-per-species) losses and C = species(or abundances-per-species) gains. B-C plots were produced; they display visually the relative importance of the loss and gain components, through time, across the ***, temporal analysis: In BCI, quadrats with significant TBI indices were found in the swamp area, which is shrinking in importance due to changes to the local climate. A published habitat classification divided the BCI forest plot into six habitat zones. Graphs of the B and C components were produced for each habitat group. Group 4(the swamp) was dominated by species(and abundances-per-species) gains whereas the five other habitat groups were dominated by losses, some groups more than ***: We identified the species that had changed the most in abundances in the swamp between T1 and *** analysis supported the hypothesis that the

关键词： Beta diversity B-C plots BCI forest dynamics plot Space-time analysis Temporal beta diversity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

microbial starch-binding domains are superior to granule-bound starch synthase I for anchoring luciferase to potato starch granules

引用

Progress in Natural Science:materials International 2006年第12期16卷 1295-1299页

作者： Jean-Paul VINCKEN Luc C.J.m. SUURS richard G.F. VISSER Laboratory of Plant Breeding Department of Plant Sciences Wageningen University Wageningen The Netherlands

microbial starch-binding domains (SBD) and granule-bound starch synthase I (GBSSI) are proteins which are accumulated in potato starch granules. The efficiency of SBD and GBSSI for targeting active luciferase reporter proteins to granules during starch biosynthesis was compared. GBSSI or SBD sequences were fused to the N- or C-terminus of the luciferase (LUC) gene, via an artificial Pro-Thr encoding linker sequence. The genes were introduced into an amylose-free (amf) potato mutant. It appeared that SBD was superior to GBSSI as a targeting sequence, mainly because the luciferase retained higher activity in the SBD-containing fusion proteins than in the GBSSI-containing ones.

关键词： luciferase GBSS I SBD amf potato.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Persistent X-ray-activated phosphors:mechanisms and applications

引用

Light(Science & Applications) 2022年第6期11卷 1008-1010页

作者： Cyrille richard Bruno Viana UniversitéParis Cité CNRSINSERMUTCBSUnitéde Technologies Chimiques et Biologiques pour la SantéFacultéde Pharmacie75006 ParisFrance IRCP CNRS UMR8247PSL UniversityChimie ParisTech11 Rue P&M Curie75005 ParisFrance

Trivalent lanthanides in wide bandgap fluoride or phosphate hosts can present persistent luminescence between 200 nm and 1.7 μm after charging by *** are reviewed and applications envisioned.

关键词： lanthanide fluoride luminescence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：