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Immobilization and Properties of Lipase from Candida rugosa on Electrospun Nanofibrous Membranes with Biomimetic Phospholipid Moities

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Chemical Research in Chinese Universities 2008年第2期24卷 231-237页

作者： huang xiao-jun yu an-guo ge dan xu zhi-kang Institute of Polymer Science Key Laboratory of Macromolecular Synthesis and Functionalization of Ministry of Education State Key Laboratory of Chemical Engineering Zhejiang University Hangzhou 310027 P. R. China

Reported here is a protocol to fabricate a biocatalyst with high enzyme loading and activity retention, from the conjugation of electrospun nanofibrous membrane having biomimetic phospholipid moiety and lipase. To improve the catalytic efficiency and activity of the immobilized enzyme, poly（acrylonitrile-co-2-methacryloyloxyethyl phosphorylcholine）s（PANCMPCs） were, respectively, electrospun into nanofibrous membranes with a mean diameter of 90 nm, as a support for enzyme immobilization. Lipase from Candida rugosa was immobilized on these nanofibrous membranes by adsorption. Properties of immobilized lipase on PANCMPC nanofibrous membranes were compared with those of the lipase immobilized on the polyacrylonitrile（PAN） nanofibrous and sheet membranes, respectively. Effective enzyme loading on the nanofibrous membranes was achieved up to 22.0 mg/g, which was over 10 times that on the sheet membrane. The activity retention of immobilized lipase increased from 56.4% to 76.8% with an increase in phospholipid moiety from 0 to 9.6%（molar fraction） in the nanofibrous membrane. Kinetic parameter Km was also determined for free and immobilized lipase. The Km value of the immobilized lipase on the nanofibrous membrane was obviously lower than that on the sheet membrane. The optimum pH was 7.7 for free lipase, but shifted to 8.3-8.5 for immobilized lipases. The optimum temperature was determined to be 35 ℃ for the free enzyme, but 42-44℃ for the immobilized ones, respectively. In addition, the thermal stability, reusability, and storage stability of the immobilized lipase were obviously improved compared to the free one.

关键词： Biomimetic polymer Nanofibrous membrane Electrospinning Enzyme immobilization Lipase

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Synergistic inhibition of polyethylene glycol and potassium chloride in water-based drilling fluids

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Petroleum Science 2021年第3期18卷 827-838页

作者： dan-Chao huang Gang Xie Ni-yuan Peng Jian-guo Zou Yao xu Ming-Yi Deng Wei-Chao Du yu-Rong xiao Jin-jun huang Ping-Ya Luo State Key Laboratory of Oil&Gas Reservoir geology and Exploitation Southwest Petroleum UniversityChengdu 610500SichuanChina College of Chemistry and Chemical Engineering Southwest Petroleum UniversityChengdu 610500SichuanChina College of Chemistry and Chemical Engineering Xi’an Shiyou UniversityXi’an 710056ShanxiChina

Mud shale hydration and swelling are major challenges in the development of water-based drilling fuids(WBDFs).In this work,the inhibition performance and inhibition mechanism of polyethylene glycol(PEG)and potassium chloride(KCl)were investigated by hot rolling recovery tests,linear swell tests,Fourier transform infrared spectroscopy,X-ray difraction,atomic absorption spectrophotometry and X-ray photoelectron *** experimental results show that the combination of PEG and KCl achieved higher recovery and lower linear swelling rate than those obtained by individual PEG or *** to the d-spacing of Na-montmorillonite(Na-Mt)with PEG or KCl,the d-spacing of Na-Mt with PEG+KCl was lower,which indicates that KCl and PEG have synergistic inhibition *** synergistic efect can replace sodium ions and water molecules from the interlayer space of Na-Mt and decrease the d-spacing of *** on the above experimental results and analysis,a method for optimizing PEG and KCl concentrations was proposed and further verifed by rheological and hot rolling recovery tests of ***,the results of this work can provide valuable theoretical guidance for developing other synergistic inhibitors.

关键词： Clay hydration Inhibitor Synergistic inhibition Polyethylene glycol Water-based drilling fuids

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Naoxintong Capsule for Secondary Prevention of Ischemic Stroke:A Multicenter,Randomized,and Placebo-Controlled Trial

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Chinese Journal of Integrative Medicine 2022年第12期28卷 1063-1071页

作者： yu xiao-fei ZHU xu-ying yuAN Can-xing WU dan-hong ZHAO yu-wu YANG Jia-jun WANG Chang-de WUWei-wen LIU xue-yuan LIU Zhen-guo NIE zhi-yu DENG Ben-qiang BAO Huan LI Long-xuan WANG Chun-yan ZHANG Hong-zhi ZHANG Jing-si huang Ji-han GONG Fan WANG Ming-zhe guo Yong-mei SUN Yan CAI Ding-fang Department of Neurology and Institute of NeurologyShuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Neurology Longhua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200030China DepartmentofNeurology Shanghai Third People'sHospitalAffiliatedto Shanghai JiaoTongUniversityShanghai 201900China Department of Neurology Shanghai SixthPeople's Hospital Affiliated to Shanghai Jiao TongUniversityShanghai 200233China Department of Neurology Shanghai Sixth People's Hospital East BranchShanghai 201306China Department of Neurology Shanghai TCM-Integrated Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200083China Department of Neurology Zhongshan Hospital Qingpu Branch Affiliated to Fudan UniversityShanghai 201799China Department of Neurology Shanghai Tenth People's Hospital Affiliated to Tongji UniversityShanghai 200072China Department of Neurology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Neurology Shanghai Tongji Hospital Affiliated to Tongji UniversityShanghai 200065China Department of Neurology Changhai HospitalShanghai 200433China Department of Neurology Orient Hospital Affiliated to Tongji UniversityShanghai 200120China Department of Neurology Shanghai Pudong New Area Gongli HospitalShanghai 200135China Department of Neurology Shanghai Yangpu Hospital of Traditional Chinese MedicineShanghai 200090China Center for Drug Clinical Research Shanghai University of Traditional Chinese MedicineShanghai 201203China

Objective:To examine whether the combination of Naoxintong Capsule with standard care could further reduce the recurrence of ischemic stroke without increasing the risk of severe ***:A total of 23 Chinese medical centers participated in this *** patients with a history of ischemic stroke were randomlyassigned ina 1:1ratiousing a blockdesign toreceive eitherNaoxintong Capsule(1.2gorally,twice a day)or placebo in addition to standard *** primary endpoint was recurrence of ischemic stroke within 2 *** outcomes included myocardial infarction,death due to recurrent ischemic stroke,and all-cause *** safety of drugs was *** were analyzed using the intention-to-treat principle.

关键词： ischemic stroke Naoxintong Capsule secondary prevention randomized controlled trial Chinese medicine

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Measurement of the neutron total cross section of carbon at the Back-n white neutron beam of CSNS

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Nuclear Science and Techniques 2019年第9期30卷 73-82页

作者： Xing-Yan Liu Yi-Wei Yang Rong Liu Jie Wen Zhong-Wei Wen Zi-Jie Han zhi-Zhou Ren Qi An Huai-Yong Bai Jie Bao Ping Cao Qi-Ping Chen Yong-Hao Chen Pin-Jing Cheng Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Feng-Qin guo Chang-Cai Han guo-Zhu He Yong-Cheng He yue-Feng He Han-Xiong huang Wei-Ling huang Xi-Ru huang xiao-Lu Ji xu-Yang Ji Hao-yu Jiang Wei Jiang Han-Tao Jing Ling kang Ming-Tao kang Bo Li Lun Li Qiang Li xiao Li Yang Li Yang Li Shu-Bin Liu Guang-yuan Luan Ying-Lin Ma Chang-jun Ning Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Hong Sun xiao-Yang Sun zhi-Jia Sun zhi-Xin Tan Hong-Qing Tang Jing-yu Tang Peng-Cheng Wang Qi Wang Tao-Feng Wang Yan-Feng Wang Zhao-Hui Wang Zheng Wang Qing-Biao Wu xiao-Guang Wu xuan Wu Li-Kun Xie Han Yi Li yu Tao yu Yong-Ji yu guo-Hui Zhang Jing Zhang Lin-Hao Zhang Li-Ying Zhang Qing-Min Zhang Qi-Wei Zhang Xian-Peng Zhang yu-Liang Zhang zhi-Yong Zhang Ying-Tan Zhao Liang Zhou Zu-Ying Zhou dan-Yang Zhu Ke-jun Zhu Peng Zhu Institute of Nuclear Physics and Chemistry China Academy of Engineering Physics State Key Laboratory of Particle Detection and Electronics Chinese Academy of Sciences(CAS) Department of Modern Physics University of Science and Technology of China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking University Key Laboratory of Nuclear Data China Institute of Atomic Energy Institute of High Energy Physics Chinese Academy of Sciences(CAS) Spallation Neutron Source Science Center University of South China Northwest Institute of Nuclear Technology Department of Engineering and Applied Physics University of Science and Technology of China Beihang University Xi’an Jiaotong University

To verify the performance of the neutron total cross-sectional spectrometer, the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method. The measurement is performed at the Back-n white neutron source with a 76-m time-of-flight path using the China Spallation Neutron Source. A multilayer fast fission chamber with 235U and 238U is employed as the neutron detector. The diameter and thickness of the natural graphite sample are 70 mm and 40 mm, respectively. Signal waveforms are collected using a data acquisition system. Off-line data processing was used to obtain the neutron time-of-flight spectra and transmissions. The uncertainty of the counting statistics is generally approximately 3% for each bin in the energy range of 1–20 MeV. It is determined that the results for the neutron total cross section of carbon obtained using ^235U cells are in good agreement with the results obtained using 238U cells within limits of statistical uncertainty. Moreover, the measured total cross sections show good agreement with the broadening evaluated data.

关键词： CSNS Back-n white neutron source NTOX Neutron total cross section Carbon Multilayer fast fission chamber

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Multigene phylogeny of the family Cordycipitaceae (Hypocreales): new taxa and the new systematic position of the Chinese cordycipitoid fungus Paecilomyces hepiali

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Fungal Diversity 2020年第4期103卷 1-46页

作者： yuan-Bing Wang Yao Wang Qi Fan Dong-E Duan guo-Dong Zhang Ru-Qin Dai Yong-Dong Dai Wen-Bo Zeng Zi-Hong Chen dan-dan Li De-Xiang Tang zhi-Hong xu Tao Sun Thi-Tra Nguyen Ngoc-Lan Tran Van-Minh Dao Can-Ming Zhang Luo-Dong huang Yong-jun Liu xiao-Mei Zhang Da-Rong Yang Tatiana Sanjuan Xing-Zhong Liu Zhu L.Yang Hong yu yunnan Herbal Laboratory School of Ecology and Environmental ScienceYunnan UniversityKunming 650091China The International Joint Research Center for Sustainable Utilization of Cordyceps Bioresources in China and Southeast Asia Yunnan UniversityKunming 650091China The Research Center of Cordyceps Development and Utilization of Kunming Yunnan Herbal Biotech Co.Ltd.Kunming 650106China CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China yunnan Key Laboratory for Fungal Diversity and Green Development Kunming 650201China Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China College of Evironment and Resources Wenshan UniversityWenshan 663099China Institute of Biological Resources of Gaoligong Mountains Baoshan UniversityBaoshan 678000China Institute of Regional Research and Development Ministry of Science and TechnologyHanoiVietnam YikangBao Biotech Co. LtdShangri-La 674400China School of Chemical Science and Engineering Yunnan UniversityKunming 650091China College of Basic Medicine Yunnan University of Chinese MedicineKunming 650500China Key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesKunming 650223China Laboratorio de Taxonomíay Ecología de Hongos Universidad de Antioquiacalle 67 No.53-12108A.A.1226MedellinColombia State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China

The phylogeny and systematics of cordycipitoid fungi have been extensively studied in the last two ***,systematic positions of some taxa in the family Cordycipitaceae have not yet been thoroughly *** this study,a new phylogenetic framework of Cordycipitaceae is reconstructed using multigene(nrSSU,nrLSU,tef-1α,rpb1 and rpb2)sequence data with large-scale taxon *** addition,ITS sequence data of species belonging to the Lecanicillium lineage in the family Cordycipitaceae are used to further determine their phylogenetic *** on molecular phylogenetic data together with morphological evidence,two new genera(Flavocillium and Liangia),16 new species and four new combina-tions are *** the new genus Flavocillium,one new species *** and three new combinations previously described as Lecanicillium,namely ***,*** and ***,are *** genus Liangia is built by the new species *** with Lecanicillium-like asexual morph,isolated from an entomopathogenic fungus Beauveria *** to the absence of Paecilomyces hepiali,an economically and medically significant fungus,in the earlier phylogenetic analyses,its systematic position has been puzzling in both business and academic communities for a long ***,*** is recharacterized using the holotype material along with seven additional *** is assigned to the genus Samsoniella(Cordycipitaceae,Hypocreales)possessing Cordyceps-like sexual morph and Isaria-like asexual morph,and thus a new combination,namely *** is *** additional nine new species in Samsoniella are described:***,***,***,***,***,***,***,*** and *** new species in Cordyceps are described:***,***,*** and *** yunnanense,isolated from synnemata of Akanthomyces waltergamsii,is described as a new species.

关键词： Cordycipitaceae Cordyceps Flavocillium Liangia Paecilomyces hepiali Phylogeny Samsoniella

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COVID-ONE-hi:The One-stop Database for COVID-19-specific Humoral Immunity and Clinical Parameters

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genomics, Proteomics & Bioinformatics 2021年第5期19卷 669-678页

作者： Zhaowei xu Yang Li Qing Lei Likun huang dan-yun Lai Shu-juan guo He-wei Jiang Hongyan Hou yun-xiao Zheng xue-ning Wang Jiaoxiang Wu Ming-liang Ma Bo Zhang Hong Chen Caizheng yu jun-biao xue Hai-nan Zhang Huan Qi Siqi yu Mingxi Lin Yandi Zhang xiaosong Lin Zongjie Yao Huiming Sheng Ziyong Sun Feng Wang Xionglin Fan Sheng-ce Tao Shanghai Center for Systems Biomedicine Key Laboratory of Systems Biomedicine(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Gastrointestinal Cancer(Fujian Medical University) Ministry of EducationSchool of Basic Medical SciencesFujian Medical UniversityFuzhou 350122China Department of Pathogen Biology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Fujian Key Laboratory of Crop Breeding by Design Key Laboratory of GeneticsBreeding and Multiple Utilization of CropsMinistry of EducationFujian Agriculture and Forestry UniversityFuzhou 350028China Department of Clinical Laboratory Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Tongren Hospital Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Public Health Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China

Coronavirus disease 2019(COVID-19),which is caused by SARS-CoV-2,varies with regard to symptoms and mortality rates among *** immunity plays critical roles in SARS-CoV-2 infection and recovery from ***,differences in immune responses and clinical features among COVID-19 patients remain largely ***,we report a database for COVID-19-specific IgG/IgM immune responses and clinical parameters(named COVID-ONE-hi).COVID-ONE-hi is based on the data that contain the IgG/IgM responses to 24 full-length/truncated proteins corresponding to 20 of 28 known SARS-CoV-2 proteins and 199 spike protein peptides against 2360 serum samples collected from 783 COVID-19 *** addition,96 clinical parameters for the 2360 serum samples and basic information for the 783 patients are integrated into the ***,COVID-ONE-hi provides a dashboard for defining samples and a one-click analysis pipeline for a single group or paired groups.A set of samples of interest is easily defined by adjusting the scale bars of a variety of *** the“START”button is clicked,one can readily obtain a comprehensive analysis report for further ***-ONE-hi is freely available at ***.

关键词： SARS-CoV-2 Protein microarray Humoral immunity One-stop tool Shiny

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Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1198-1207页

作者： Hai-Dong Zhu Hai-Liang Li Ming-Sheng huang Wei-Zhu Yang guo-Wen Yin Bin-Yan Zhong jun-Hui Sun zhi-Cheng Jin Jian-Jian Chen Nai-Jian ge Wen-Bin Ding Wen-Hui Li Jin-Hua huang Wei Mu Shan-zhi Gu Jia-Ping Li Hui Zhao Shu-Wei Wen Yan-Ming Lei yu-Sheng Song Chun-Wang yuan Wei-Dong Wang Ming huang Wei Zhao Jian-Bing Wu Song Wang xu Zhu Jian-jun Han Wei-Xin Ren Zai-Ming Lu Wen-ge Xing Yong Fan Hai-Lan Lin Zi-Shu Zhang guo-Hui xu Wen-Hao Hu Qiang Tu Hong-Ying Su Chuan-Sheng Zheng Yong Chen xu-Ya Zhao Zhu-Ting Fang Qi Wang Jin-Wei Zhao Ai-Bing xu Jian xu Qing-Hua Wu Huan-Zhang Niu Jian Wang Feng Dai Dui-Ping Feng Qing-Dong Li Rong-Shu Shi Jia-Rui Li Guang Yang Hai-Bin Shi Jian-Song Ji yu-E Liu Zheng Cai Po Yang Yang Zhao xiao-Li Zhu Li-Gong Lu Gao-jun Teng Center of Interventional Radiology&Vascular Surgery Department of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009China Department of Minimally invasive Intervention The Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450008China Department of Interventional Radiology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630China Department of Interventional Radiology Union Hospital of Fujian Medical UniversityFuzhou 350001China Department of Interventional Radiology Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009China Department of Interventional Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Interventional Radiology Eastern Hospital of Hepatobiliary SurgeryNavy Medical University(Second Military Medical University)Shanghai 200438China Department of Interventional Radiology Nantong First People’s HospitalNantong 226001China Department of Interventional Radiology Yancheng Third People’s HospitalYancheng 224008China Department of Minimally Invasive Interventional Therapy Sun YatSen University Cancer CenterGuangzhou 510060China Department of Vascular Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China. Department of Interventional Radiology Hunan Cancer HospitalChangsha 410031China Department of Interventional Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Department of Interventional Radiology The Hospital of Nantong UniversityNantong 226001China Department of Interventional Therapy Shanxi Tumor HospitalTaiyuan 030001China Department of Interventional Radiology Tibet Autonomous Region People’s

There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE combined with PD-(L)1 inhibitors and MTT in real-world *** this nationwide,retrospective,cohort study,826 HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(combination group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2018 to May *** primary endpoint was progression-free survival(PFS)according to modified *** secondary outcomes included overall survival(OS),objective response rate(ORR),and *** performed propensity score matching approaches to reduce bias between two *** matching,228 pairs were included with a predominantly advanced disease *** PFS in combination group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002).OS and ORR were also significantly higher in combination group(median OS,19.2[16.1-27.3]vs.15.7 months[13.0-20.2];adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;Pgest that TACE plus PD-(L)1 blockades and MTT could significantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile.

关键词： hepatocellular targeted matching

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International consensus on natural orifice specimen extraction surgery(NOSES)for gastric cancer(2019)

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Gastroenterology Report 2020年第1期8卷 5-10,I0001页

作者： xu Guan Zheng Liu Amjad Parvaiz Antonio Longo Avanish Saklani Ali AShafik Jian-Chun Cai Charles Ternent Lin Chen Cuneyt Kayaalp Fatih Sumer Fernanda Nogueira Feng Gao Fang-Hai Han Qing-Si He Ho-Kyung Chun Chang-Ming huang Hai-Yang huang Rui huang zhi-Wei Jiang Jim S Khan Joaquim Manuel da Costa Pereira JosephWNunoo-Mensah jung Tack Son Liang kang Keisuke Uehara Ping Lan Le-Ping Li Han Liang Bing-Rong Liu Juan Liu dan Ma Ming-Yin Shen Mohammad Rashidul Islam Narimantas Evaldas Samalavicius Kai Pan Petr Tsarkov Xin-yu Qin Ricardo Escalante Sergey Efetov Seung Kyu Jeong Suk-Hwan Lee Dong-Hui Sun Li Sun Tatiana Garmanova Yan-Tao Tian Gui-yu Wang guo-jun Wang guo-Rong Wang xiao-Qiang Wang William Tzu-Liang Chen Woo Yong Lee Su Yan Zu-Li Yang Gang yu Pei-Wu yu dan Zhao yun-Shi Zhong Jian-Ping Wang Xi-Shan Wang The International Alliance of NOSES Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingP.R.China Poole Hospital NHS Trust PooleUK European Center of Coloproctology and Pelvic Diseases-Multimedica Hospital MilanItaly Department of GI Surgical Oncology Tata Memorial HospitalMumbaiIndia Department of Colorectal Surgery Cairo UniversityCairoEgypt Department of Gastrointestinal Surgery Zhongshan Hospital of Xiamen UniversityXiamenFujianP.R.China Section of Colon and Rectal Surgery Creighton University School of MedicineOmahaNEUSA Department of general Surgery Chinese People’s Liberation Army General HospitalBeijingP.R.China Department of Gastrointestinal Surgery Inonu UniversityMalatyaTurkey Department of Surgery Hospital de BragaBragaPortugal Department of Colorectal Cancer Surgery the Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangP.R.China Department of Gastroenterological Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of general Surgery Shandong University Qilu HospitalJinanShandongP.R.China Department of Surgery Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulSouth Korea Department of Gastric Surgery Fujian Medical University Union HospitalFuzhouFujianP.R.China Department of general Surgery Jiangsu Province Hospital of Traditional Chinese MedicineNanjingJiangsuP.R.China Department of Colorectal Surgery PortsmouthHospitals NHSTrustQueen Alexandra HospitalPortsmouthUK King’s College Hospital LondonUK Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Division of Surgical Oncology Department of SurgeryNagoya University School of MedicineNagoyaJapan Department of Gastrointestinal Surgery Shandong Provincial Hospital Affiliated to Shandong UniversityJinanShandongP.R.China Department of Gastric Cancer

At present,natural orifice specimen extraction surgery(NOSES)has attracted more and more attention worldwide,because of its great advantages including minimal cutaneous trauma and post-operative pain,fast post-operative recovery,short hospital stay,and positive psychological ***,NOSES for the treatment of gastric cancer(GC)is still in its infancy,and there is great potential to improve its theoretical system and clinical ***,several key points including oncological outcomes,bacteriological concerns,indication selection,and standardized surgical procedures are raised with this innovative ***,it is necessary to achieve an international consensus to regulate the implementation of GC-NOSES,which is of great significance for healthy and orderly development of NOSES worldwide.

关键词： gastric cancer natural orifice specimen extraction surgery transanal specimen extraction transvaginal specimen extraction transoral specimen extraction consensus

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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin Liu yue huang Guang-Cheng xiao Qing-Cui Bu Jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia Fang-jun Lu Xiang Ma Lian Tao Wei Zhang Li Chen Li-Ming Song Ti-Pei Li yu-Peng xu xue-Lei Cao Yong Chen Cong-Zhan Liu Ce Cai zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen yu-Peng Chen Wei Cui Wei-Wei Cui Jing-kang Deng Yong-Wei Dong yuan-yuan Du Min-xue Fu Guan-Hua Gao He Gao Min Gao Ming-yu ge yu-Dong Gu Ju Guan Cheng-Cheng guo Da-Wei Han Jia Huo Lu-Hua Jiang Wei-Chun Jiang Jing Jin Yong-Jie Jin Ling-Da Kong Bing Li Cheng-Kui Li Gang Li Mao-Shun Li Wei Li Xian Li xiao-Bo Li xu-Fang Li Yang-guo Li Zheng-Wei Li xiao-Hua Liang Jing-yuan Liao Bai-Sheng Liu guo-Qing Liu Hong-Wei Liu xiao-Jing Liu Yi-Nong Liu Bo Lu xue-Feng Lu Qi Luo Tao Luo Bin Meng Yi Nang Jian-Yin Nie ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song Liang Sun Ying Tan You-Li Tuo Chen Wang guo-Feng Wang Juan Wang Ling-jun Wang Weng-Shuai Wang yu-Sa Wang Xiang-Yang Wen Bai-Yang Wu Bo-Bing Wu Mei Wu Shuo xiao Shao-Lin Xiong He xu Jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-jung Yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang Wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang yuan-Hang Zhang yue Zhang Zhao Zhang zhi Zhang Zi-Liang Zhang Hai-Sheng Zhao xiao-Fan Zhao Shi-Jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-Feng Zhou yu-xuan Zhu Ren-Lin Zhuang yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng xiao-Wei Liu Yi-Peng Jing Gang Wang Hao-Tong Zhang Jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu guo-Ping Li Zhong-Rui Bai yue Wu Yan Cai Shu-yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-yuan Chen Jian-jun Chen Kun-Xin Chen Li Chen xue-Lei Chen xiao-Yan Chen Ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning Fu Peng Gao xue-Fei Gong Bo-Zhong Gu Yan-Xin guo Zhan-Wen Han Bo-Liang He Jin-Liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu zhi-Ying Huo Lei Jia Fang-Hua Jiang Xiang Jiang zhi-Bo Jiang ge Jin xiao Kong xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li Guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li Yin-Bi Li Ye-Ping Li yuan Liang Chien-Cheng Lin Chao Liu gen-Rong Liu Guan-Qun Liu zhi-Gang Liu Wen-zhi Lu yu Luo Yin-Dun Mao Heidi Newberg Ji-jun Ni Zhao-Xiang Qi Yong-jun Qi Shi-Yin Shen Huo-Ming Shi Jing Song Yi-Han Song Ding-Qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng Tao yuan Tian dan Wang Da-Qi Wang Feng-Fei Wang guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang yue-Fei Wang You-Fen Wang Peng Wei Ming-zhi Wei Hong Wu Ke-Fei Wu xue-Bing Wu yu-Zhong Wu xiao-Zheng Xing Ling-Zhe xu Xin-Qi xu Yan xu Tai-Sheng Yan De-Hua Yang Hai-Feng Yang Hui-Qin Yang Ming Yang Zheng-Qiu Yao Yong yu Hui yuan Hai-Bo yuan Hai-Long yuan Wei-Min yuan Chao Zhai En-Peng Zhang Hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang Yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

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