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哈尔滨轴承 2021年第1期42卷 39-41页

作者：贾媛媛皇天鸣冯斌郭晓阳李海强洛阳LYC轴承有限公司河南洛阳471039

根据浪型保持架结构特点,设计了一款检测保持架径向游动量的测量装置。该测量装置准确度高,操作简单、快捷,适用性广,可用于中、小型浪型保持架的生产加工、过程控制、出厂验收。

关键词：球轴承浪型保持架径向游动量测量

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十个侧耳菌株的模糊综合评价初报

食用菌学报 1999年第1期6卷 43-46页

作者：郁建强蔡云霞殷戎一黄丹枫庄天明上海农学院上海201101

应用模糊数学中隶属度和模糊概率概念,对10个侧耳菌株进行了模糊综合评价。结果表明,SN1是表现最好的菌株,与实际试验结果较为一致。

关键词：隶属度模糊概率侧耳菌株综合评价食用菌

Upregulation of Zip14 correlates with induction of endoplasmic reticulum stress(ERS)in hypertrophied hearts of Dahl saltsensitive rats

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BIOCELL 2022年第3期46卷 667-675页

作者： JINYONG huang tianming TENG BO BIAN YUCHEN XUE LONGFEI huang ZHELONG XU QING YANG YUEMIN SUN Department of Cardiology Tianjin Medical University General HospitalTianjin300052China Department of Physiology&Pathophysiology Tianjin Medical UniversityTianjin300070China

Zinc is a trace element involved in maintaining cellular structure and *** zinc is associated with left ventricular hypertrophy(LVH),there have been few reports on this *** study aimed to evaluate the correlation between Zip14 and expression of endoplasmic reticulum stress(ERS)associated molecules in hypertrophied hearts of *** salt-sensitive rats were fed a high salt diet to establish a left ventricular hypertrophy(LVH)rat ***-PCR was used to determine Zip14,activating transcription factor(ATF4),ATF6,x-box-binding protein 1(xBP1),C/EBP homologous protein(CHOP),immunoglobulin-binding protein(BiP)mRNA *** blotting was used to evaluate Zip14,BiP,CHOP,GAPDH *** levels were measured by Inductively Coupled Plasma Optical Emission *** results indicated that compared with the Control group,Zip14 mRNA and protein expression in LVH rat hearts were markedly increased(P<0.01).Zinc content in rat heart tissue was significantly increased in the LVH group compared with the Control group(P<0.05).ATF4,ATF6,xBP1 mRNA expressions were increased in LVH rat hearts compared with Control hearts(P<0.001).Compared with the Control group,CHOP and BiP mRNA and protein expression were markedly increased in LVH rat hearts(P<0.05,P<0.01).Linear regression models showed that Zip14 mRNA expressions were positively correlated with zinc concentration,ATF4 and ATF6 mRNA expressions in Control hearts(P=0.0005,P=0.0052,P=0.0026,respectively)and LVH rat hearts(P<0.0001,P=0.0119,P=0.0033,respectively).In conclusion,upregulation of Zip14 in LVH rat hearts correlated with zinc accumulation and induction of ERS.

关键词： Zinc Zip14 Endoplasmic reticulum stress(ERS) Left ventricular hypertrophy(LVH) Rat hearts

GCF2选择性剪接区在肝癌组织及细胞株中的表达及意义

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广西医科大学学报 2014年第3期31卷 355-357页

作者：陈力李金平晁耐霞吴博陈德凤黄天明罗国容广西医科大学基础医学院组织与胚胎学教研室南宁530021

目的：研究肿瘤相关抗原GCF2选择性剪接区在人肝癌细胞株、肝癌组织、癌旁组织及正常成人肝细胞及组织中的表达及意义.方法：采用RT PCR检测GCF2 5个选择性剪接区（D1～D5）在人肝癌细胞株、43例肝癌组织、相对应的癌旁组织,以及正常成... 详细信息

目的：研究肿瘤相关抗原GCF2选择性剪接区在人肝癌细胞株、肝癌组织、癌旁组织及正常成人肝细胞及组织中的表达及意义.方法：采用RT PCR检测GCF2 5个选择性剪接区（D1～D5）在人肝癌细胞株、43例肝癌组织、相对应的癌旁组织,以及正常成人肝细胞株及9例肝组织中的表达.结果：GCF2 4个选择性剪接区（D1～D4）在所检测的细胞株、肝癌组织、癌旁组织和正常成人肝组织中均未检测到表达;GCF2选择性剪接区D5仅在人肝癌细胞株检测到阳性表达;在43例肝癌组织及相应的癌旁组织中,有41例肝癌组织GCF2选择性剪接区D5呈阳性表达,阳性表达率为95.35％（41/43）,而9例正常肝组织均未检测到GCF2选择性剪接区D5表达.结论：GCF2 D5选择性剪接区在肝癌组织中有较高阳性表达,GCF2选择性剪接区D5可能与肝癌的发生发展有关.

关键词： GCF2 选择性剪接区肝癌

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麦草生料栽培平菇技术原理与应用

上海农学院学报 1999年第4期17卷 309-313页

作者：郁建强殷戎一黄丹枫庄天明蔡云霞上海农学院植物科学系上海201101

本文简要地总结了麦草生料栽培平菇的技术、原理及应用情况。

关键词：麦草生料栽培平菇技术原理应用

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基于深度学习的非视距可见光定位系统

光通信研究 2024年第6期6期(19)卷 114-120页

作者：黄伟杰林邦姜丁永棋骆加彬黄天明福建农林大学机电工程学院福州350100 中国科学院海西研究院泉州装备制造研究中心福建泉州362200

【目的】可见光定位(VLP)技术在提供低成本、高精度的室内位置服务方面极具潜力,受到越来越多的关注。然而,传统的VLP系统依赖于直接视距(LOS)路径,在有障碍物遮挡的情况下无法正常进行工作。【方法】针对这一问题,文章提出了一种基于... 详细信息

【目的】可见光定位(VLP)技术在提供低成本、高精度的室内位置服务方面极具潜力,受到越来越多的关注。然而,传统的VLP系统依赖于直接视距(LOS)路径,在有障碍物遮挡的情况下无法正常进行工作。【方法】针对这一问题,文章提出了一种基于深度学习的非视距(NLOS)VLP系统,该系统创新地利用一次反射光来进行VLP,克服了LOS路径被遮挡的挑战,提高了VLP系统的鲁棒性。考虑到反射光信号信噪比较低,通过传统的图像检测方法来提取发光二极管(LED)光斑的准确度较低并且环境适应性较差,导致NLOS VLP的定位精度下降。因此,文章所提系统通过深度学习模型U型网络(U-Net)来检测LED光斑,通过采集不同环境下的数据集进行训练,U-Net模型表现出了很高的准确度和环境适应性,从而改善了系统的性能。在此基础上,文章所提系统利用三点透视几何(P3P)算法来估计接收端的三维(3D)位置。【结果】文章搭建了1.84 m×1.84 m×1.96 m的立体空间模拟室内环境,用于室内定位实验,实验结果表明,在NLOS路径下,系统3D平均误差和均方根误差(RMSE)分别为16.09和17.18 cm,二维(2D)定位误差小于21 cm时有90%的置信度,3D定位误差小于24 cm时有90%的置信度。【结论】文章所提系统具有较高的精度和鲁棒性,能够满足室内大多数应用场景的定位需求。

关键词：可见光定位非视距深度学习三点透视几何算法

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New norlignan enantiomers from the fruit of Crataegus pinnatifida with neuroprotective activities

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Chinese Chemical Letters 2020年第5期31卷 1254-1258页

作者： Rui Guo tianming Lv Fengying Han Zilin Hou Guodong Yao Bin Lin Xiaobo Wang Xiaoxiao huang Shaojiang Song Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research&Development Liaoning ProvinceSchool of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyang 110016China School of Pharmaceutical Engineering Shenyang Pharmaceutical UniversityShenyang 110016China Chinese People's Liberation Army Logistics Support Force No.967 Hospital Dalian 116021China

(±)-Crataegusnorin A(la/1b) and B(2a/2b),two pairs of rare 8,9’-epoxy-type norlignan enantiomers featuring a y-butyrolactone ring,were isolated from the fruit of Crataegus *** structures were determined via extensive spectroscopic ***-independent atomic orbital(GIAO) NMR chemical shift calculations,combined with the advanced statistical method DP4+were employed to establish the relative configurations of four ***,chiral separation was accomplished by chiral chromatographic column and the absolute configurations of the four compounds were unambiguously assigned by comparison between their experimental electronic circular dichroism curves with the quantum-mechanically calculated curves based on time-dependent density functional theory(TDDFT).All the isolates were evaluated fo r their neuroprotective activities against H2O2-induced cell injury in human neuroblastoma SH-SY5Y *** results showed that two pairs of enantiomers 1a/1b and 2a/2b displayed diff;erent effect on neuroprotective *** them,compound 2a displayed the most potent neuroprotective effect Further flow cytometry analysis indicated that 2a could protect SH-SY5Y cells from oxidative damage through inhibiting cell apoptosis.

关键词： Crataegus pinnatifida Norlignan enantiomer Neuroprotective activity SH-SY5Y cells Apoptosis

Development Opportunity and Capacity Building of Social Organizations

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International Understanding 2014年第1期 27-29页

作者： huang Haoming Zhao tianming

The third plenary session of the 18thCentral Committee of the Communist Party of China held in November 2013 studied a number of major issues for comprehensively deepening reforms and made sixty significant decisions in political reform,economic development,social governance,cultural development,ecological civilization,foreign affairs and military system,among

关键词： political deepening governance affairs sixty sessi

Functional diversity of subgroup 5 R2R3-MYBs promoting proanthocyanidin biosynthesis and their key residues and motifs in tea plant

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Horticulture Research 2023年第8期10卷 216-230页

作者： tianming Jiao Yipeng huang Ying-Ling Wu Ting Jiang Tongtong Li Yanzhuo Liu Yvchen Liu Yunyun Han Yajun Liu Xiaolan Jiang Liping Gao Tao Xia State Key Laboratory of Tea Plant Biology and Utilization/Key Laboratory of Tea Biology and Tea Processing of Ministry of Agriculture/Anhui Provincial Laboratory of Tea Plant Biology and Utilization Anhui Agricultural UniversityWest 130 Changjiang RoadHefei 230036 AnhuiChina School of Life Science Anhui Agricultural UniversityHefei 230036AnhuiChina

The tea plant(Camellia sinensis)is rich in polyphenolic ***,flavan-3-ols and proanthocyanidins(PAs)are essential for the flavor and disease-resistance property of tea *** fifth subgroup of R2R3-MYB transcription factors comprises the primary activators of PA *** study showed that subgroup 5 R2R3-MYBs in tea plants contained at least nine genes belonging to the TT2,MYB5,and MYBPA ***-rich plants showed an expansion in the number of subgroup 5 R2R3-MYB genes compared with other dicotyledonous and monocot *** MYBPA-type genes of tea plant were slightly ***–PCR analysis and GUS staining analysis of promoter activity under a series of treatments revealed the differential responses of CsMYB5s to biotic and abiotic *** particular,CsMYB5a,CsMYB5b,and CsMYB5e responded to high-intensity light,high temperature,MeJA,and mechanical wounding,whereas CsMYB5f and CsMYB5g were only induced by *** genetic transformation systems(***,Nicotiana tabacum,and Arabidopsis thaliana)were used to verify the biological function of *** results show that CsMYB5a,CsMYB5b,and CsMYB5e could promote the gene expression of CsLAR and ***,CsMYB5f and CsMYB5g could only upregulate the gene expression of CsLAR but not CsANR.A series of site-directed mutation and domain-swapping experiments were used to verify functional domains and key amino acids of CsMYB5s responsible for the regulation of PA *** study aimed to provide insight into the induced expression and functional diversity model of PA biosynthesis regulation in tea plants.

关键词： plant wound residues

Research review in the main chemical constituents and pharmacological effects of Daphne acutiloba Rehd

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Asian Journal of Traditional Medicines 2019年第3期14卷 155-164页

作者： tianming Lv Rui Guo Xiaoxiao huang Department of Natural Products Chemistry Key Laboratory of Computational Chemistry- Based Natural Antitumor drug Research & Development Ministry of Education School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

Daphne acutiloba Rehd., belonging to Daphne genus of Thymelaeaceae is an evergreen shrub mainly distributed in the west of China. The roots, stem barks, leaves and fruits of this plant had been used as folk medicines for the treatment of rheumatoid arthriths, apoplesia and stomachache ache. Daphne diterpenes and tieranes diterpenes, guaiacane type sesquiterpene, lignans, diflavane and flavonoids, sterides, aliphatics and phenols were isolated from Daphne acutiloba Rehd. Researches demonstrated that the main chemical constituents of D. acutiloba Rehd. have multiple activities and good development prospect. This paper is presented as a review centering on the main chemical constituents and pharmacological effects of D. acutiloba Rehd. for the further research and development of this plant.

关键词： Daphne acutiloba Rehd. chemical constituents pharmacological effects research review