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Prediction and quantification of effective gas source rocks in a lacustrine basin: Western Depression in the Liaohe Subbasin, China

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Petroleum Science 2024年第4期21卷 2218-2239页

作者： Si-Bo Yang mei-Jun Li Hong Xiao Fang-Zheng Wang Guo-Gang Cai Shuang-Quan huang State Key Laboratory of Petroleum Resources and Prospecting College of Geosciences China University of Petroleum China University of Petroleum-Beijing at Karamay College of Petroleum Research Institute of Petroleum Exploration and Development Liaohe Oilfield Company PetroChina

Due to limited data on the geochemical properties of natural gas, estimations are needed for the effective gas source rock in evaluating gas potential. However, the pronounced heterogeneity of mudstones in lacustrine successions complicates the prediction of the presence and geochemical characteristics of gas source rocks. In this paper, the Liaohe Subbasin of Northeast China is used as an example to construct a practical methodology for locating effective gas source rocks in typical lacustrine basins. Three types of gas source rocks, microbial, oil-type, and coal-type, were distinguished according to the different genetic types of their natural gas. A practical three-dimensional geological model was developed, refined, and applied to determine the spatial distribution of the mudstones in the Western Depression of the Liaohe Subbasin and to describe the geochemical characteristics(the abundance, type, and maturation levels of the organic matter). Application of the model in the subbasin indicates that the sedimentary facies have led to heterogeneity in the mudstones, particularly with respect to organic matter types. The effective gas source rock model constructed for the Western Depression shows that the upper sequence(SQ2) of the Fourth member(Mbr 4) of the Eocene Shahejie Formation(Fm) and the lower and middle sequences(SQ3 and SQ4) of the Third member(Mbr 3) form the principal gas-generating interval. The total volume of effective gas source rocks is estimated to be 586 km3. The effective microbial, oil-type, and coal-type gas source rocks are primarily found in the shallow western slope, the central sags, and the eastern slope of the Western Depression, respectively. This study provides a practical approach for more accurately identifying the occurrence and geochemical characteristics of effective natural gas source rocks, enabling a precise quantitative estimation of natural gas reserves.

关键词： Effective gas source rock 3D geological modeling Spatial distribution Geochemical characteristics Lacustrine rift basin

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Add-on perceptual learning on refractive amblyopia in children

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1850-1856页

作者： Heng-Chiao huang Wan-Hua Cho Po-Chiung Fang Pei-Wen Lin Yi-Hao Chen Hsiu-mei huang Department of Ophthalmology Chang Gung Memorial HospitalChiayi 613TaiwanChina Department of Ophthalmology Chi-Mei Medical CenterTainan 710TaiwanChina Department of Ophthalmology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung City 833TaiwanChina School of Medicine Chang Gung UniversityTaoyuan City 333TaiwanChina

AIM:To evaluate the visual outcomes of standard amblyopic treatment add-on training via perceptual learning in refractive amblyopic children and to identify the risk factors for treatment ***:Retrospective charts were reviewed in children with refractive amblyopia who received standard treatment and add-on Cambridge Visual Stimulator(CAM)*** add-on CAM group that was enrolled had worn full-corrected glasses for at least 2mo before training.A control group received only the standard *** success was defined as best-corrected visual acuity(BCVA)≥20/*** age,sex,initial BCVA,refractive errors,sessions and duration of training,and final BCVA were ***:A total of 209 children(129 children in add-on CAM group and 80 children in control group)were ***-six percent of unilateral and 87%of bilateral amblyopic children achieved treatment *** children with unilateral or bilateral moderate amblyopia,the duration to reach BCVA≥20/25 was significantly shorter in add-on CAM group than in control *** initial BCVA(P<0.001)and high astigmatism(P=0.007)were risk factors for treatment failure after add-on CAM ***,sex,and types of refractive error were not associated with treatment ***:Add-on CAM training is an effective strategy for visual improvement and can shorten the treatment course when the effect of standard treatment is limited in amblyopic children.

关键词： amblyopia amblyopic children add-on Cambridge Visual Stimulator training astigmatism

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Method for detector description conversion from DD4hep to Filmbox

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Nuclear Science and Techniques 2024年第9期35卷 115-126页

作者： Zhao-Yang Yuan Tian-Zi Song Yu-Jie Zeng Kai-Xuan huang Yu-mei Zhang Zheng-Yun You School of Physics Sun Yat-sen UniversityGuangzhou 510275China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China

DD4hep serves as a generic detector description toolkit recommended for offline software development in next-generation high-energy physics(HEP)***,Filmbox(FBX)stands out as a widely used 3D modeling file format within the 3D software *** this paper,we introduce a novel method that can automatically convert complex HEP detector geometries from DD4hep description into 3D models in the FBX *** feasibility of this method was dem-onstrated by its application to the DD4hep description of the Compact Linear Collider detector and several sub-detectors of the super Tau-Charm facility and circular electron-positron collider *** automatic DD4hep–FBX detector conversion interface provides convenience for further development of applications,such as detector design,simulation,visualization,data monitoring,and outreach,in HEP experiments.

关键词： Detector description DD4hep FBX Geometry Offline software

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Epiphytic zooplankton community profiles in a typical urban wetland as revealed by DNA metabarcoding

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Journal of Oceanology and Limnology 2024年第5期42卷 1571-1585页

作者： Diwen LIANG Chunrong huang Senjie LIN Jiahua dong Mingyi LIANG Hailin LUO State Environmental Protection Key Laboratory of Urban Ecological Simulation and Protection South China Institute of Environmental SciencesMinistry of Ecology and Environment of the People’s Republic of ChinaGuangzhou 510530China Department of Marine Sciences University of ConnecticutGrotonConnecticut 06340USA

Zooplankton,a crucial component of urban wetland,are one of the effective bioindicators for monitoring the feeding stocks of organisms at higher trophic levels and assessing the ecological quality of ***,information about the characteristics of epiphytic zooplankton community structure resulted from traditional methods is limited and hindered by the large amount of detritus and sludge attached to the *** investigated the epiphytic zooplankton communities associated with macrophytes(Vallisneria,Nymphaea,and Thalia dealbata)in a subtropical wetland using as DNA markers of the 18 S rRNA gene and the mitochondrial cytochrome c oxidase subunit I(COI)gene.A total of 241 OTUs of zooplankton were obtained from COI amplicons,including 194 OTUs of Rotifera,22 of Cladocera,and 25 of Copepoda,while only 62 OTUs of zooplankton were obtained from 18 S rDNA amplicons including 34 OTUs of Rotifera and 28 of *** zooplankton communities associated with the three macrophytes were similar,but they differed significantly from those in the open ***,there were no significant temporal differences among the zooplankton *** zooplankton communities were dominated by littoral zooplankton such as Testudinella,Lecane,and ***,especially littoral species,utilize macrophytes as food sources and as refuges against *** further led to an increase inαandβdiversity of zooplankton communities in urban *** result suggests that the joint use of multiple molecular markers could improve the taxonomic resolution and generate a comprehensive biodiversity profile of zooplankton.

关键词： environmental DNA metabarcoding diversity macrophyte cytochrome c oxidase subunit I(COI) 18 S rRNA

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Causal role of immune cells in obstructive sleep apnea hypopnea syndrome:Mendelian randomization study

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World Journal of Clinical Cases 2024年第7期12卷 1227-1234页

作者： huang-Hong Zhao Zhen Ma dong-Sheng Guan Department of Encephalopathy Henan Provincial Hospital of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina Department of Personnel The First Affiliated Hospital of Henan University of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina Department of Neurology Henan Provincial Hospital of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina

BACKGROUND Despite being one of the most prevalent sleep disorders,obstructive sleep apnea hypoventilation syndrome(OSAHS)has limited information on its immunologic *** immunological underpinnings of certain major psychiatric diseases have been uncovered in recent years thanks to the extensive use of genome-wide association studies(GWAS)and genotyping techniques using highdensity genetic markers(e.g.,SNP or CNVs).But this tactic hasn't yet been applied to *** a Mendelian randomization analysis,we analyzed the causal link between immune cells and the illness in order to comprehend the immunological bases of *** To investigate the immune cells'association with OSAHS via genetic methods,guiding future clinical *** A comprehensive two-sample mendelian randomization study was conducted to investigate the causal relationship between immune cell characteristics and *** statistics for each immune cell feature were obtained from the GWAS *** on 731 immune cell properties,such as morphologic parameters,median fluorescence intensity,absolute cellular,and relative cellular,was compiled using publicly available genetic *** results'robustness,heterogeneity,and horizontal pleiotropy were confirmed using extensive sensitivity *** Following false discovery rate(FDR)correction,no statistically significant effect of OSAHS on immunophenotypes was ***,two lymphocyte subsets were found to have a significant association with the risk of OSAHS:Basophil%CD33dim HLA DR-CD66b-(OR=1.03,95%CI=1.01-1.03,P<0.001);CD38 on IgD+CD24-B cell(OR=1.04,95%CI=1.02-1.04,P=0.019).CONCLUSION This study shows a strong link between immune cells and OSAHS through a gene approach,thus offering direction for potential future medical research.

关键词： Obstructive sleep apnea hypopnea syndrome Immunity Causal inference MR analysis Sensitivity

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Regulation role of miR-204 on SIRT1/VEGF in metabolic memory induced by high glucose in human retinal pigment epithelial cells

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1232-1237页

作者： Qiao-Ling Lai Ting Xie Wei-dong Zheng Yan huang Department of Ophthalmology Renmin Hospital of Wuhan UniversityWuhan 460060Hubei ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina Department of Ophthalmology&Optometry Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina

AIM:To examine the regulatory role of microRNA-204(miR-204)on silent information regulator 1(SIRT1)and vascular endothelial growth factor(VEGF)under highglucose-induced metabolic memory in human retinal pigment epithelial(hRPE)***:Cells were cultured with either normal(5 mmol/L)or high D-glucose(25 mmol/L)concentrations for 8d to establish control and high-glucose groups,*** induce metabolic memory,cells were cultured with 25 mmol/L D-glucose for 4d followed by culture with 5 mmol/L D-glucose for *** addition,exposed in 25 mmol/L D-glucose for 4d and then transfected with 100 nmol/L miR-204 control,miR-204 inhibitor or miR-204 mimic in 5 mmol/L D-glucose for *** reverse transcription-polymerase chain reaction(RT-qPCR)was used to detect miR-204 mRNA ***1 and VEGF protein levels were assessed by immunohistochemical and Western *** cytometry was used to investigate apoptosis ***:It was found that high glucose promoted miR-204 and VEGF expression,and inhibited SIRT1 activity,even after the return to normal glucose culture *** of miR-204 promoted apoptosis inhibiting SIRT1 and increasing VEGF ***,downregulation of miR-204 produced the opposite ***:The study identifies that miR-204 is the upstream target of SIRT1and VEGF,and that miR-204 can protect hRPE cells from the damage caused by metabolic memory through increasing SIRT1 and inhibiting VEGF expression.

关键词： human retinal pigment epithelial metabolic memory microRNA-204 silent information regulator 1 vascular endothelial growth factor high-glucose

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Searching for the optimal precondition procedure for mesenchymal stem/stromal cell treatment:Facts and perspectives

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World Journal of Stem Cells 2024年第6期16卷 615-618页

作者： Yu-dong Zhao Yong-Can huang Wei-Shi Li Department of Orthopedic Peking University Third HospitalBeijing 100191China Shenzhen Engineering Laboratory of Orthopaedic Regenerative Technologies Orthopaedic Research CenterPeking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina

Mesenchymal stem/stromal cells are potential optimal cell sources for stem cell therapies,and pretreatment has proven to enhance cell vitality and *** a recent publication,Li et al explored a new combination of pretreatment ***,we present an editorial to comment on their work and provide our view on mesenchymal stem/stromal cell precondition.

关键词： Mesenchymal stem cell Precondition Hypoxia Inflammation

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Screening the optimal Co_(x)/CeO_(2)(110)(x=1–6)catalyst for methane activation in coalbed gas

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International Journal of Coal Science & Technology 2024年第3期11卷 256-271页

作者： Li’nan huang Danyang Li Lei Jiang Zhiqiang Li dong Tian Kongzhai Li Engineering Research Center of Metallurgical Energy Conservation and Emission Reduction Ministry of EducationKunming University of Science and TechnologyKunming650093China Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Kunming University of Science and TechnologyKunming650093China

The challenges posed by energy and environmental issues have forced mankind to explore and utilize unconventional energy *** is imperative to convert the abundant coalbed gas(CBG)into high value-added products,i.e.,selective and efficient conversion of methane from *** activation,known as the“holy grail”,poses a challenge to the design and development of *** structural complexity of the active metal on the carrier is of particular *** this work,we have studied the nucleation growth of small Co clusters(up to Co_(6))on the surface of CeO_(2)(110)using density functional theory,from which a stable loaded Co/CeO_(2)(110)structure was selected to investigate the methane activation *** the relatively small size of the selected Co clusters,the obtained Co_(x)/CeO_(2)(110)exhibits interesting *** optimized Co_(5)/CeO_(2)(110)structure was selected as the optimal structure to study the activation mechanism of methane due to its competitive electronic structure,adsorption energy and binding *** energy barriers for the stepwise dissociation of methane to form CH3^(*),CH2^(*),CH^(*),and C^(*)radical fragments are 0.44,0.55,0.31,and 1.20 eV,respectively,indicating that CH^(*)dissociative dehydrogenation is the rate-determining step for the system under investigation *** fundamental study of metal-support interactions based on Co growth on the CeO_(2)(110)surface contributes to the understanding of the essence of Co/CeO_(2) catalysts with promising catalytic *** provides theoretical guidance for better designing the optimal Co/CeO_(2) catalyst for tailored catalytic reactions.

关键词： Co cluster growth Ce-based catalysts Methane activation DFT

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外挂物投放问题的二维非结构动态网格技术研究

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空气动力学学报 2006年第1期24卷 73-79页

作者：黄冬梅童水光陈德华浙江大学浙江杭州310027 中国空气动力学研究与发展中心绵阳621000

以动态网格守恒型方程为控制方程,在二维非结构网格基础上发展了弹簧式光顺法和局部网格重构法两种动态网格变形技术。结合运动轨迹计算方程,将动态网格法应用于飞机外挂物投放问题中,成功模拟了导弹自由投放的整个过程,获得了详细的包... 详细信息

以动态网格守恒型方程为控制方程,在二维非结构网格基础上发展了弹簧式光顺法和局部网格重构法两种动态网格变形技术。结合运动轨迹计算方程,将动态网格法应用于飞机外挂物投放问题中,成功模拟了导弹自由投放的整个过程,获得了详细的包括弹体运动速度、运动轨迹和受力情况等在内的丰富的流场信息。成功的应用不仅验证了动态网格法的可行性;而且也表明,动态网格法的进一步完善与发展将成为解决外挂物投放问题的有力工具。

关键词：外挂物投放二维非结构动态网格

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不同高度处烟颗粒形貌特征和尺度分布

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工程热物理学报 2017年第11期38卷 2472-2478页

作者：郭晨宁黄冬梅张明振中国计量大学质量与安全工程学院杭州310018 浙江省家具检测技术研究重点实验室杭州310018

火灾中产生的烟颗粒严重影响火场人员疏散及灭火救援工作,而且造成严重的大气污染。本研究利用自行搭建的小尺寸实验台,开展不同燃料火灾实验,采集不同高度处烟颗粒样品,利用场发射扫描电镜,观察不同燃料不同高度处的烟颗粒形貌,分析烟... 详细信息

火灾中产生的烟颗粒严重影响火场人员疏散及灭火救援工作,而且造成严重的大气污染。本研究利用自行搭建的小尺寸实验台,开展不同燃料火灾实验,采集不同高度处烟颗粒样品,利用场发射扫描电镜,观察不同燃料不同高度处的烟颗粒形貌,分析烟颗粒形貌特征及其尺度分布。研究表明,随着采样高度的增加,烟颗粒团聚体逐渐增多且结构越来越蓬松;煤油和柴油燃烧产生的烟颗粒粒径在50~70 nm的范围内。

关键词：粒子团聚形貌特征粒度分布 SEM

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