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Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy:A Multicenter Double-Blind Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第3期30卷 195-202页

作者： huang hao-yue LIN Yu-ping WEI Hua FU Yu ZHOU yue-hong FANG Zhao-hui QIU Xiao-tang WANG Mei LI Qing-bo LI Shan-shan WANG Shi-dong DAI Fang LIU Zhen-jie Zhao Ling WEN Jian-xuan WU Li-yan ZENG Hui-yan ZHANG Jin-ming LU Qi-yun HE Liu SONG Wei SUN Lu LUO Lu-lu HE Jia-li XIE Wen-wen LIANG Qing-shun huang Yuan ZHU Sheng-ling LONG Jie-er GAO Zhi-juan WEN Ze-huai LI Chun-ji OUYANG Wen-wei LI Geng WU Ming-hui LI An-xiang huang Jin-zhu Sanjoy K Paul TANG Xian-yu FAN Guan-jie Department of Endocrinology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou510120China Department of Endocrinology The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou510120China Guangdong Provincial Academy of Chinese Medical Sciences Guangzhou510120China Department of Endocrinology The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Endocrinology Liuyang Hospital of Chinese MedicineChangsha410000China Department of Endocrinology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230000China Department of Endocrinology Hainan Provincial Hospital of Traditional Chinese MedicineHaikou570100China Department of Endocrinology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang110000China Department of Geriatric Luoyang No.1 Hospital of Traditional Chinese MedicineLuoyangHenan Province471000China Department of Endocrinology The Second Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Department of Endocrinology Beijing University of Chinese Medicine Affiliated Dongzhimen HospitalBeijing100000China Department of Endocrinology The First Affiliated Hospital of Guizhou University of Traditional Chinese MedicineGuiyang550000China Melbourne EpiCentre The University of Melbourne and Melbourne HealthMelbourne3013Australia

Objective:To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction(TW)in treating patients with diabetic peripheral neuropathy(DPN).Methods:It is a multicenter double-blinded randomized controlled *** with DPN were recruited between November 18,2016 and May 30,2018 from 8 hospitals in *** patients received basic treatments for glycemic *** received foot baths with TW herbal granules either 66.9 g(intervention group)or 6.69 g(control group)for 30 min once a day for 2 weeks and followed by a 2-week rest,as a therapeutic *** the Toronto Clinical Scoring System total score(TCSS-TS)6 points,the patients received a total of 3 therapeutic courses(for 12 weeks)and were followed up for 12 *** primary outcome was change in TCSS-TS score at 12 and 24 *** outcomes included changes in bilateral motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of the median and common peroneal *** was also ***:Totally 632 patients were enrolled,and 317 and 315 were randomized to the intervention and control groups,*** the 12-week intervention,patients in both groups showed significant declines in TCSSTS scores,and significant increases in MNCV and SNCV of the median and common peroneal nerves compared with pre-treatment(P0.05),and no serious adverse event was related with ***:Treatment of TW foot baths was safe and significantly benefitted patients with DPN.A low dose of TW appeared to be more effective than a high dose.(Registry *** CTR-IOR-16009331)

关键词： diabetic peripheral neuropathy herbal medicine foot baths Chinese medicine randomized controlled trial Tangbi Waixi Decoction

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Machine learning-assisted smart epitaxy ofⅢ-Ⅴsemiconductors

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Science China Materials 2024年第9期67卷 3041-3042页

作者： yue hao Key Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian UniversityXi’an710071China

Semiconductor epitaxial growth is the front-end process for manufacturing microelectronic and optoelectronic *** beam epitaxy(MBE),capable of precisely controlling atomic layer deposition,has emerged as a crucial technique in chip atomic-level manufacturing[1].However,in semiconductor epitaxy,the heterogeneous nature of materials is complicated,and the growth condition fluctuations poses significant challenges in defect suppression[2],substantially impacting chip performance and yield.

关键词： optoelectronic smart semiconductors

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A small organic molecule strategy for remedying oxygen vacancies by bismuth defects in BiOBr nanosheet with excellent photocatalytic CO_(2)reduction

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Nano Research 2024年第1期17卷 297-306页

作者： Jing Xie Zhenjiang Lu yue Feng Jianguo huang Jindou Hu Aize hao Yali Cao State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources College of ChemistryXinjiang UniversityUrumqi 830046China

Defect modulation currently plays a decisive role in addressing the poor photoabsorption,sluggish electron hole separation,and high CO_(2)activation barrier in photocatalytic CO_(2)***,hunting for a straightforward strategy to balance the concentration of oxygen vacancy and metal cation defect in one photocatalyst is still a great ***,a bismuth vacancies BiOBr nanosheets(BiOBr-1)on the exposed[001]facets were constructed via an acetic acid molecule modification strategy,which can repair oxygen defect by bismuth vacancy in low-temperature solid-state chemical *** from the formed bismuth defects that can not only broaden light absorption and elevate charge separation efficiency,but also enhance adsorption and activation of CO_(2)molecules,the evolution rates of photocatalytic CO_(2)conversion into CO(71.23μmol·g^(-1)·h^(-1))and CH4(8.90μmol·g^(-1)·h^(-1))attained by BiOBr-1 are superior 7.1 and 11 times to that of plate-like *** photocatalytic mechanisms including adsorption concentration and activation process of CO_(2)are further revealed by the in situ diffuse reflectance infrared flourier transform spectra(DRIFTS).This finding of the existence of distinct defects in ultrathin nanosheets undoubtedly leads to new possibilities for photocatalyst design using two-dimensional materials with high solar-driven photocatalytic activity.

关键词： solid-state synthesis BiOBr metal vacancies photocatalysis carbon dioxide reduction

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Self-polarized RGB device realized by semipolar micro-LEDs and perovskite-in-polymer films for backlight applications

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Opto-Electronic Advances 2024年第3期7卷 35-49页

作者： Tingwei Lu yue Lin Tianqi Zhang yue huang Xiaotong Fan Shouqiang Lai Yijun Lu hao-Chung Kuo Zhong Chen Tingzhu Wu Rong Zhang School of Electronic Science and Engineering Fujian Engineering Research Center for Solid-State LightingXiamen UniversityXiamen 361005China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005China Department of Photonics and Graduate Institute of Electro-Optical Engineering College of Electrical and Computer EngineeringYang Ming Chiao Tung UniversityHsinchu 30010China Semiconductor Research Center Hon Hai Research InstituteTaipei 11492China.

In backlighting systems for liquid crystal displays,conventional red,green,and blue(RGB)light sources that lack polarization properties can result in a significant optical loss of up to 50%when passing through a *** address this inefficiency and optimize energy utilization,this study presents a high-performance device designed for RGB polarized *** device employs an array of semipolar blueμLEDs with inherent polarization capabilities,coupled with mechanically stretched films of green-emitting CsPbBr3 nanorods and red-emitting CsPbI3-Cs4PbI6 hybrid *** CsPbBr3 nanorods in the polymer film offer intrinsic polarization emission,while the aligned-wire structures formed by the stable CsPbI3-Cs4PbI6 hybrid nanocrystals contribute to substantial anisotropic emissions,due to their high dielectric *** resulting device achieved RGB polarization degrees of 0.26,0.48,and 0.38,respectively,and exhibited a broad color gamut,reaching 137.2%of the NTSC standard and 102.5%of the Rec.2020 *** compared to a device utilizing c-plane LEDs for excitation,the current approach increased the intensity of light transmitted through the polarizer by 73.6%.This novel fabrication approach for polarized devices containing RGB components holds considerable promise for advancing next-generation display technologies.

关键词： halide perovskite light-emitting-diodes polarized emission nanocrystals stability

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Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer’s Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice

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Neuroscience Bulletin 2024年第2期40卷 182-200页

作者： Yang Zhu hao huang Zhi Chen Yong Tao Ling-Yi Liao Shi-hao Gao Yan-Jiang Wang Chang-yue Gao Department of Rehabilitation Medicine Daping HospitalArmy Medical UniversityChongqing 400042China Department of Neurology and Center for Clinical Neuroscience Daping HospitalArmy Medical UniversityChongqing 400042China Department of Special Medicine Daping HospitalArmy Medical UniversityChongqing 400042China

Intermittent theta burst stimulation(iTBS),a time-saving and cost-effective repetitive transcranial magnetic stimulation regime,has been shown to improve cognition in patients with Alzheimer’s disease(AD).However,the specific mechanism underlying iTBS-induced cognitive enhancement remains *** studies suggested that mitochondrial functions are modulated by magnetic ***,we showed that iTBS upregulates the expression of iron-sulfur cluster assembly 1(ISCA1,an essential regulatory factor for mitochondrial respiration)in the brain of APP/PS1 *** vivo and in vitro studies revealed that iTBS modulates mitochondrial iron-sulfur cluster assembly to facilitate mitochondrial respiration and function,which is required for ***,iTBS rescues cognitive decline and attenuates AD-type pathologies in APP/PS1 *** present study uncovers a novel mechanism by which iTBS modulates mitochondrial respiration and function via ISCA1-mediated iron-sulfur cluster assembly to alleviate cognitive impairments and pathologies in *** provide the mechanistic target of iTBS that warrants its therapeutic potential for AD patients.

关键词： Intermittent theta burst stimulation Alzheimer’s disease Iron-sulfur cluster assembly 1 Mitochondrial dysfunction Neurodegeneration

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青海热贡地区传统建筑彩画颜料光谱特征分析研究

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光谱学与光谱分析 2022年第11期42卷 3519-3525页

作者：黄跃昊金永泽西北民族大学中国语言文学学部甘肃兰州730030 兰州交通大学建筑与城市规划学院甘肃兰州730070

青海省热贡地区是安多藏区藏式建筑彩画艺术的重要产地,作为热贡艺术的重要组成部分影响甚广。热贡地方建筑彩画不仅是附着建筑栋梁之上的艺术瑰宝,更是一项延续至今的传统技艺,至今仍有大批传统匠人画师从事相关行业。热贡地方建筑彩... 详细信息

青海省热贡地区是安多藏区藏式建筑彩画艺术的重要产地,作为热贡艺术的重要组成部分影响甚广。热贡地方建筑彩画不仅是附着建筑栋梁之上的艺术瑰宝,更是一项延续至今的传统技艺,至今仍有大批传统匠人画师从事相关行业。热贡地方建筑彩画有独立的用色方法和颜料制作工艺,对其所用传统颜料进行科学检测是系统研究该地区建筑彩画的基础性工作,在进一步研究热贡地区建筑彩画的制作工艺和艺术特色,传承地方建筑彩画技艺和完善保护政策等方面具有积极意义。通过对同仁市隆务寺夏日仓行宫火供殿所用当地传统建筑彩画颜料的采样,运用X射线荧光光谱、X射线衍射分析、激光显微拉曼光谱分析等多种实验分析方法,对颜料样品进行分析,测定其主要显色物质和成分占比。结果表明,热贡地方建筑彩画所用颜料多为无机颜料;蓝色颜料主要是人造群青;绿色颜料的主要矿物组成为绿土,显色物质为蒙脱石,存在将植物色染料加入当地所产的富镁蒙脱石中混合使用的可能性;红色颜料的主要矿物组成为铁红(赭石类红土),通过焙烧富铁矿土来人工合成,材料来自于当地吾屯村所产红色赭石类粘土;黄色颜料主要矿物组成为密陀僧、硫磺及其他植物色染料制备而成;黑色颜料为碳黑,符合木炭黑的性状特征;白色颜料主要为生石灰及氧化镁粉,并在其他颜料中广泛使用石灰及氧化镁粉作为调色颜料;推测部分样品中含有包金土及植物色素染料、其他人工合成颜料的可能性。整体来看,热贡地区建筑彩画所用颜料成本价格较低,制取难度不大,来源大多是当地常见的矿土料和动植物染料,传统的制料工艺较简单,颜料多呈现为组分复杂的混合物状态;密陀僧、包金土和群青等颜料多来自于内地及国外,颜料人工合成的历史较早,反映出热贡地区建筑彩画在颜料使用上不仅使用本土材料制备,也广泛使用外来颜料的历史传统,为进一步研究热贡地区建筑彩画领域内汉、藏等多民族文化交往、交流、交融历史提供了良好实证材料。

关键词：热贡地区建筑彩画颜料光谱特征

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Chromosome-level assembly of triploid genome of Sichuan pepper(Zanthoxylum armatum)

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Horticultural Plant Journal 2024年第2期10卷 437-449页

作者： Lizhi Song yue huang hao Zuo Ning Tang Zhengguo Li Wenbiao Jiao Feng Xu Qiang Xu Zexiong Chen National Key Laboratory for Germplasm Innovation and Utilization for Fruit and Vegetable Horticultural Crops Huazhong Agricultural UniversityWuhanHubei 430070China Chongqing Key Laboratory of Economic Plant Biotechnology Chongqing University of Arts and SciencesChongqing 402160China School of Life Sciences Chongqing UniversityChongqing 400030China College of Horticulture and Gardening Yangtze UniversityJingzhouHubei 434025China College of Informatics Huazhong Agricultural UniversityWuhanHubei 430070China

As an important spice species in Rutaceae, the Sichuan pepper (Zanthoxylum armatum) can provide pungent and numbing taste, as well as aroma in its mature fruit. Here we assembled a chromosome-level genome of green prickly ash which was widely cultivated in a major production area including Chongqing and Sichuan province, China. We generated 712 Gb (~112×) PacBio long reads and 511 Gb (~82×) Hi-C data, and yielded an assembly of 99 pseudochromosomes with total size of 5.32 Gb and contig N50 of 796 kb. The genomic analyses and cytogenetic experiments both indicated that the cultivarZhuye Huajiao’ was a triploid. We identified a Zanthoxylum-specific whole genome duplication event emerging about 24.8 million years ago (Mya). We also detected a transposition burst event (0.3-0.4 Mya) responsible for the large genome size of Z. armatum. Metabolomic analysis of the Zanthoxylum fruits during development stages revealed profiles of39 volatile aroma compounds and 528 secondary metabolites, from which six types of sanshools were identified. Based on metabolomic and transcriptomic network analysis, we screened candidate genes encoding long chain acyl-CoA synthetase, fatty acid desaturase,branched-chain amino acid aminotransferase involved in sanshool biosynthesis and three genes encoding terpene synthase during fruit development. The multi-omics data provide insights into the evolution of Zanthoxylum and molecular basis of numbing and aroma flavor of Sichuan pepper.

关键词： Zanthoxylum armatum Genome Sanshool Terpenoid

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Full-domain collaborative deployment method of multiple interference sources and evaluation of its deployment effect

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Defence Technology（防务技术） 2024年第2期32卷 572-595页

作者： yue Wang Fuping Sun Xian Wang Jinming hao Kai Xiao School of Geospatial Information The PLA Information Engineering UniversityZhengzhou 450001HenanChina

This paper realizes the full-domain collaborative deployment of multiple interference sources of the global satellite navigation system(GNSS)and evaluates the deployment effect to enhance the ability to disturb the attacker and the capability to defend the GNSS during navigation *** evaluation indicators for the jamming effect of GNSS suppressive and deceptive jamming sources are first created,their evaluation models are built,and their detection procedures are sorted out,as the basis for determining the deployment *** principles for collaboratively deploying multi-jamming sources are developed to obtain the deployment structures(including the required number,structures in demand,and corresponding positions)of three single interference sources required by collaboratively ***,simulation and hardware-in-loop testing results are presented to determine a rational configuration of the collaborative deployment of multi-jamming sources in the set situation and further realize the full-domain deployment of an interference network from ground,air to *** evaluation indices for the deployment effect are finally developed to evaluate the deployment effect of the proposed configuration and further verify its reliability and rationality.

关键词： Jamming effect Multiple interference sources Collaborative deployment Effect evaluation Defense capability

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Self-powered and self-sensing devices based on piezoelectric energy harvesting

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Science China(Technological Sciences) 2024年第6期67卷 1631-1667页

作者： CHEN GanTong ZHU yue huang DongMei ZHOU ShengXi School of Aeronautics Northwestern Polytechnical UniversityXi’an710072China School of Mathematics and Statistics Xidian UniversityXi’an710071China

Wearable devices,interactive human-machine interface equipment,wireless sensors,and small-scale cleaning devices play crucial roles in biomedical implantation,disease treatment,health monitoring,environmental purification,*** devices require a sustainable energy source to work *** the consideration of the global energy crisis and environmental pollution,researchers are exploring new,stable,and environmentally friendly methods to power these low-powered *** energy is one of the most abundant natural energy *** mechanical energy from the ambient environment or host structures into electrical energy via the direct piezoelectric effect is an efficient energy harvesting *** paper reviews the application of advanced piezoelectric materials,and small-scale self-powered and self-sensing piezoelectric devices at the cubic centimeter scale in energy harvesting and health monitoring of human,animal,machinery,roads,bridges,as well as the pollutant degradation of the *** of these devices have the capability to not only harvest mechanical energy but also enable real-time monitoring and analysis of the electrical signals generated by the direct piezoelectric effect,facilitating prompt decision-making and appropriate *** addition,potential challenges and future prospects of small-scale self-powered and self-sensing piezoelectric devices are discussed.

关键词： piezoelectric energy harvesting self-powered self-sensing wearable devices implantable devices

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MoS2 as a cocatalyst applied in advanced oxidation processes for enhancing degradation of organic pollutants: a review

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Tungsten 2024年第3期6卷 473-487页

作者： Ming-hao Fan Cong-Hui Wang Xiang Yu Jun Ding Ao-Qi Xiao yue Li Wei-Ya huang School of Material Science and Engineering Henan Polytechnic University School of Chemical and Printing-Dyeing Engineering Henan International Joint Laboratory of Rare Earth Composite Materials Henan University of Engineering School of Chemistry and Chemical Engineering Jiangxi University of Science and Technology Department of Chemical and Environmental Engineering University of Cincinnati

Fenton technology,as a typical advanced oxidation processes（AOPs）,can generate reactive oxygen species（ROS） of strong oxidation capacity to degrade organic pollutants,which has attracted wide ***,it is accompanied by the slow Fe3+/Fe2+cycle rate,easy to generate iron sludge and so ***,it has been proven that the inorganic cocatalysts represented by MoS2can effectively solve the above ***,MoS2can accelerate the activation of peroxy mono sulfate（PMS） and peroxodisulfate（PDS） by Fe2+.In this paper,MoS2as the cocatalyst in H2O2+Fe2+,PMS+Fe2+and PDS+Fe2+were comprehensively ***,the cycling processes of Fe3+/Fe2+in different systems,the cocatalytic effect of MoS2by the exposed active sites,the ROS generation mechanism as well as the microscopic mechanism during the reaction were elaborated *** results indicate that the reductive active sites on the surface of MoS2can promote the regeneration of Fe2+through the cycle between Fe3+/Fe2+and Mo4+/Mo5+/Mo6+.Thus,ROS such as ·OH,SO4·-and1O2with strong oxidizing property can be produced to improve the degradation efficiency of organic *** last,the challenges and developments of MoS2cocatalysts in AOPs for practical applications were *** review contributes to a deeper understanding of the cocatalytic effect of two-dimensional metal sulfides in AOPs and facilitates their industrial application.

关键词： Cocatalyst Fenton reaction Degradation of organic pollutant Molybdenum disufide Reactive oxygen species

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