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The Study of Retinal Nerve Fiber Layer Thickness of Normal Eyes Using Scanning Laser Polarimetry

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眼科学报 2006年第3期22卷 175-183页

作者： Xing Liu Jingjing huang Jian ge Yunlan Ling Xiaoping Zheng Key Laboratory of Ophthalrnology of the Ministry of Education and Zhongshan OphthalmicCenter Sun Yat-sen University Guangzhou 510060 China

Purpoe: To evaluate retinal nerve fiber layer (RNFL) thickness measurements in local normal Chinese subjects of different age groups and analyse the correlation of RNFL thickness with age using scanning laser polarimetry (SLP,GDxVCC). To assess the reproducibility of RNFL thickness measurement with GDxVCC. Methods: The RNFL thickness of 67 normal subjects (123 eyes) were measured by GDxVCC. The average TSNIT parameters were calculated. The differences of RNFL thickness between sex,right and left eyes,superior and inferior were compared. The relationship between RNFL thickness and age was analyzed with correlation analysis and linear regression analysis. The intraclass correlation coefficients (ICC) of three images in every eye were calculated. Results: The average peripapillary RNFL thickness at the superior,inferior and whole ellipse regions in 123 eyes of 67 normal subjects were (70.30±6.76)(?)m,(67.35±6.77)(?)m and (56.87±4.53)(?) m,respectively. The average TNSIT standard deviation was 23.68±4.61 and the average inter-eye symmetric value was 0.86±0.11. There were significant difference of RNFL thickness between superior and inferior (t=4.952,P genders. There was a slight negative correlation average RNFL thickness in superior sector with age (decreased approximately 0.15 microns per year,P=0.047) in the subjects aged below 60 years old. The ICC values of RNFL thickness were >0.8 in superior,inferior and global. Conclusions: The RNFL thickness can be measured accurately by GDxVCC and the reproducibility of RNFL thickness measurement by GDxVCC is good. There was a slight negative correlation between average RNF

关键词： Scanning laser polarimetry Retinal nerve fiber layer Normal subjects

Multidisciplinary and Comprehensive Chinese Medicine for Advanced Non-Small Cell Lung Cancer Patients:A Retrospective Study of 855 Cases

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Chinese Journal of Integrative Medicine 2021年第7期27卷 490-495页

作者： huang Xian-ge ZHU Li-hua ZHOU Lei XU Wei-jie YAO Yi-lin ZHOU Zhi-yi LI He-gen The Third Department of Oncology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China

Objective To investigate the effects of multidisciplinary and comprehensive Chinese medicine(CM)treatments on progression-free survival(PFS)and median survival time(MST)in patients with advanced non-small cell lung cancer(NSCLC)and identify factors that influence progression and *** Clinical data of 855 patients with advanced NSCLC who received multidisciplinary and comprehensive CM treatments at Longhua Hospital from January 2009 to December 2018 were retrospectively *** analysis was performed by the Kaplan-Meier method and log-rank sequential *** analysis of significant variables from the univariate analysis was performed with Cox regression *** factors correlated to progression and prognosis were screened out,and a Cox proportional hazard model was established to calculate the prognostic *** The PFS and MST of 855 advanced NSCLC patients were 9.0 and 26.0 months,*** 1-,2-,3-,and 5-year survival rates were 79.2%,54%,36.2%,and 17.1%,***,pathologic type,and clinical stage were independent prognostic risk factors;surgical history,radiotherapy,treatment course of Chinese patent medicine,intravenous drip of Chinese herbal preparation,duration of oral administration of Chinese herbal decoction(CHD),and intervention measures were independent prognostic protective *** was an independent risk factor for progression,while operation history and oral CHD administration duration were independent protective factors(all Pge IIIb–IIIc lung adenocarcinoma had the best *** Female patients have lower progression risk and better prognoses than male patients,younger patients have higher progression risk but better long-term prognoses than the elderlys,and patients with lower performance status scores are at lower risk for progression and have better *** CM treatments could significantly reduce progression risk,improve pr

关键词： advanced non-small cell lung cancer prognostic factor progression factor survival analysis Chinese medicine

Network analysis and molecular docking of the mechanism of Shengmai decoction in treating patients with severe novel coronavirus pneumonia

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Traditional Medicine Research 2021年第4期6卷 31-45页

作者： Jia-Ting Su Xiao-Ling Li Yu-ge huang Hao-Wen Lin Hui Luo Lian-Xiang Luo The First Clinical College of Guangdong Medical University Zhanjiang 524000China Animal Experiment Center of Guangdong Medical University Zhanjiang 524000China Affiliated Hospital of Guangdong Medical University Zhanjiang 524000China The Marine Biomedical Research Institute Guangdong Medical UniversityZhanjiang 524023China

Background:Studies have shown that,Shengmai injection(Shengmai decoction)which has been included in the diagnosis and treatment of coronavirus disease 2019(COVID-19),is effective in the early treatment of patients with severe ***,the mechanism of its intervention in severe stage of COVID-19 at molecular level is still ***,it is necessary to further explore the mechanism of Shengmai decoction in the treatment of patients with severe COVID-19 based on network ***:The Traditional Chinese Medicine Systems Pharmacology,BATMAN,UniProt databases and the published literatures which contain the reported compounds that have therapeutic effects on COVID-19 were used to screen out the active ingredients and targets of Shengmai decoction,and the“drug-active compound-target”network was *** geneCards database was used to screen out the targets of *** protein-protein interaction network map was constructed by mapping two genes,and the network of active ingredients,targets and disease was constructed using Cytoscape ***,gene Ontology and Kyoto Encyclopedia of genes and genomes enrichment analyses of the key targets were performed using the Metascape Site Maintenance website and David *** gene Ontology function and Kyoto Encyclopedia of genes and genomes pathway enrichment of the mapping targets were ***:The active component-target network contained 73 main compounds and 457 *** first five main active components(hydroquinone,guanosine,ophiopogon C,ophiopogon B,ophiopogon D)were obtained by topological analysis of 33 common *** the Matthews correlation coefficient algorithm,the key targets included albumin,tumor necrosis factor,and cyclic adenosine response element *** in Shengmai decoction were found to have good binding effect and strong interaction with caspase-8,caspase-3,apoptosis regulator Bcl-2,tumor necrosis factor,C-C motif chemokine 3,to inh

关键词： Shengmai decoction Novel coronavirus pneumonia Network pharmacology Anti-inflammation Molecular docking

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中西绘画美学比较

社会科学家 2009年第2期24卷 159-160,F0003页

作者：黄戈桂林师范专科学校美术系广西桂林541001

中西绘画美学趋向之不同主要体现在:西洋油画重写实,作品以追求幻真和再现自然为其最高境界。所采用的焦点透视符合科学和数理,有助于立体和空间的表现。形似逼真,色彩浓丽,是西洋油画的特色。中国画运用笔墨直接表达生命情调,透入物象... 详细信息

中西绘画美学趋向之不同主要体现在:西洋油画重写实,作品以追求幻真和再现自然为其最高境界。所采用的焦点透视符合科学和数理,有助于立体和空间的表现。形似逼真,色彩浓丽,是西洋油画的特色。中国画运用笔墨直接表达生命情调,透入物象的核心,以书法为骨干,以诗境为灵魂,不重物象的刻画,而倾向于抽象的笔墨表达人格心情与意境。中国画散点透视的运用,摆脱了焦点透视物理和生理上的局限,增加了更大的自由和灵活性,极大地丰富了中国画的表现能力和艺术个性。通过中西绘画美学对比,达到了解、认知和认同中国传统文化,提高中华民族的自信心,是本文的匠心所在。

关键词：中国画西洋画美学趋向

基于CEGI和Fourier变换的全自动点云配准算法

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四川大学学报（工程科学版） 2014年第5期46卷 104-109页

作者：黄戈李晓峰四川大学计算机学院四川成都610064 四川大学视觉合成图形图像技术国防重点学科实验室四川成都610065

针对没有任何几何和拓扑信息的散乱点云,提出一种全自动点云数据配准算法。针对待配准的2组点云数据,首先通过局部最小二乘曲面拟合,估计每个点的法向和曲率,其次计算点云的扩展高斯图(EGI)和复扩展高斯图(CEGI),然后根据EGI和CEGI利用... 详细信息

针对没有任何几何和拓扑信息的散乱点云,提出一种全自动点云数据配准算法。针对待配准的2组点云数据,首先通过局部最小二乘曲面拟合,估计每个点的法向和曲率,其次计算点云的扩展高斯图(EGI)和复扩展高斯图(CEGI),然后根据EGI和CEGI利用球面调和函数计算旋转欧拉角,构造相关函数,通过Fourier变换估计平移向量,完成粗配准,把粗配准结果作为新的初始位置,采用最近点迭代算法(ICP)进行精确配准,从而实现2组散乱点云的精确配准。实例分析表明该算法配准速度较快,效果良好。

关键词：散乱点云数据法向曲率 EGI 3维旋转群 Fourier变换

Study on Sleep Quality and TCM Constitution of Patients with general Tonic-clonic Epilepsy

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World Journal of Integrated Traditional and Western Medicine 2022年第4期8卷 11-16页

作者： ZHAO Liang YANG Jian-zhong WANG Lian huang ge-ge Shanxi University of Chinese Medicine Taiyuan030024China Department of Neurology Shanxi Provincial People's HospitalTaiyuan 030012China Shanxi Medical University Taiyuan030012China

Objective:To explore the relationship between interseizure sleep quality and Traditional Chinese medicien(TCM)constitution in patients with generalized tonic-clonic epilepsy,and to provide theoretical and practical basis for improving sleep quality and better controlling epileptic seizures by adjusting biased constitution of epilepsy ***:Two hundred and thirty eight epilepsy patients who met the standard and went to the epilepsy clinic of Neurology Department of Shanxi Provincial People's Hospital were sampled *** basic information such as age,gender and course of disease,and test and fill out"TCM Body Mass Table"to judge TCM constitution type,"Pittsburgh Sleep Quality Index Scale"to judge sleep quality grade,and useχ^(2) test to infer whether there is any difference in sleep quality of patients with different ages,genders and course of disease;Rank sum test was used to infer whether there were differences in sleep quality among different ***:There was no significant difference in sleep quality among patients with different age,sex and course of disease(P>0.05).There were significant differences in sleep quality among patients with different constitutions(P<0.001).Among them,the number of peaceful quality groups accounted for 44.31%,and the number of biased quality groups accounted for 55.69%;There were statistically significant differences in sleep quality between calming and qi deficiency,yang deficiency,blood stasis,damp-heat,qi stagnation and yin deficiency(P<0.05);There was a significant difference between phlegm-dampness quality and qi stagnation quality in sleep quality(P<0.05).Conclusion:The sleep quality of patients with epilepsy with mild constitution is significantly higher than that of patients with biased constitution such as qi deficiency,yang deficiency,yin deficiency,damp-heat,blood stasis and qi *** addition to phlegmdampness quality and Qi stagnation quality of patients sleep quality compari

关键词： Epilepsy Traditional Chinese medicine constitution Sleep quality

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层级性与优先性:自律观念的当代分野与交融

东南学术 2022年第2期 171-177页

作者：黄各中共中央党校(国家行政学院)哲学教研部

个人自律是被当代自由主义者所频繁使用的一个概念,它通过强调人们的自由选择,弘扬一种以“自我主导”为核心的生活方式。这一概念的意蕴与康德彰显纯粹实践理性自我立法的道德自律概念截然不同。不少学者为二者找到结合点,试图发展出... 详细信息

个人自律是被当代自由主义者所频繁使用的一个概念,它通过强调人们的自由选择,弘扬一种以“自我主导”为核心的生活方式。这一概念的意蕴与康德彰显纯粹实践理性自我立法的道德自律概念截然不同。不少学者为二者找到结合点,试图发展出一种康德式个人自律,并以此来填补它们之间的裂隙和鸿沟。但康德其实早已通过意志自由和任性自由的区分,对此二者作出详细的规定。通过层级性定位的方式,这二者之间的关系可以被把握得更为明晰,从而回应当代学界围绕此主题所产生的一系列争论。

关键词：道德自律个人自律自我立法层级性角色

至善、目的王国与永久和平——康德共同体理论可实现性的三重维度

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四川师范大学学报（社会科学版） 2024年第3期51卷 57-63,201页

作者：黄各中共中央党校(国家行政学院)哲学教研部

一种常见的观点认为,康德的政治共同体与伦理共同体在立论基础、制度内容以及可实现性上均有着较大差异。前者彰显的是最高的政治善,旨在通过强制的法权与渐进的改革走向国家间的永久和平;后者则彰显的是神学层面的至善,需要预设上帝作... 详细信息

一种常见的观点认为,康德的政治共同体与伦理共同体在立论基础、制度内容以及可实现性上均有着较大差异。前者彰显的是最高的政治善,旨在通过强制的法权与渐进的改革走向国家间的永久和平;后者则彰显的是神学层面的至善,需要预设上帝作为最高的公共立法者,以此对所有人的德性法则进行普遍规定。这两种共同体理论之间的“断裂”使得康德实践哲学的系统性与整体性受到挑战。但康德同样还提到了一种目的王国共同体,它以道德世界中的至善为依托,旨在通过行动者间的道德自律达成交互责任、立法意志与平等自由的状态。这不仅向上承接了道德存在者所向往的伦理共同体,同时还向下规定了政治共同体联结的前提,为真正走向国家间的永久和平提供基础保障。

关键词：康德至善伦理共同体目的王国永久和平

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论留日经历对傅抱石画学思想之影响

浙江艺术职业学院学报 2009年第2期7卷 75-82页

作者：黄戈东南大学南京艺术学院

一直以来,日本因素对傅抱石的影响在各种研究中众说纷纭、各有见解。本文试图从傅抱石留日经历的史实入手,结合近代中日美术交流等历史情境和社会背景,从三个方面(日本画坛影响下的傅抱石画学思想之流变、日本画风影响下的傅抱石与岭南... 详细信息

一直以来,日本因素对傅抱石的影响在各种研究中众说纷纭、各有见解。本文试图从傅抱石留日经历的史实入手,结合近代中日美术交流等历史情境和社会背景,从三个方面(日本画坛影响下的傅抱石画学思想之流变、日本画风影响下的傅抱石与岭南画派之比较、日本艺术理论对傅抱石画学思想之内在影响)探讨傅抱石留学日本的经历对其绘画观念乃至风格造成的实际影响以及造成影响的深层原因,并作出合理的历史阐释,挖掘傅抱石画学思想中对日本绘画复杂而微妙的文化心态。

关键词：画学思想日本因素传统创新