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Blind adaptive constrained constant modulus algorithms based on unscented Kalman filter for beamforming

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Journal of Central South University 2017年第10期24卷 2342-2352页

作者： qian hua-ming LIU Ke JIAO Zhi-bo MA Jun-da College of Automation Harbin Engineering UniversityHarbin 150001China Hainengda Communication Co. Ltd.Shenzhen 518000China

This work proposes constrained constant modulus unscented Kalman filter(CCM-UKF) algorithm and its low-complexity version called reduced-rank constrained constant modulus unscented Kalman filter(RR-CCM-UKF) algorithm for blind adaptive beamforming. In the generalized sidelobe canceller(GSC) structure, the proposed algorithms are devised according to the CCM criterion. Firstly, the cost function of the constrained optimization problem is transformed to suit the Kalman filter-style state space model. Then, the optimum weight vector of the beamformer can be estimated by using the recursive formulas of UKF. In addition, the a priori parameters of UKF(system and measurement noises) are processed adaptively in the implementation. Simulation results demonstrate that the proposed algorithms outperform the existing methods in terms of convergence speeds, output signal-tointerference-plus-noise ratios(SINRs), mean-square deviations(MSDs) and robustness against steering mismatch.

关键词： constrained constant modulus criterion blind beamforming unscented Kalman filter generalized sidelobe canceller

Survey of plasmonic gaps tuned at sub-nanometer scale in self-assembled arrays

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Frontiers of physics 2016年第2期11卷 57-65页

作者： Li-hua qian Li-Zhi Yi Gui-Sheng Wang Chao Zhang Song-Liu Yuan School of Physics Huazhong University of Science and Technology Wuhan 430074 China Flexible Electronics Center Huazhong University of Science and Technology Wuhan 430074 China

Creating nanoscale and sub-nanometer gaps between noble metal nanoparticles is critical for the applications of plasmonics and nanophotonics. To realize simultaneous attainments of both the op- tical spectrum and the gap size, the ability to tune these nanoscale gaps at the sub-nanometer scale is particularly desirable. Many nanofabrication methodologies, including electron beam lithography, self-assembly, and focused ion beams, have been tested for creating nanoscale gaps that can de- liver significant field enhancement. Here, we survey recent progress in both the reliable creation of nanoscale gaps in nanoparticle arrays using self-assemblies and in the in-situ tuning techniques at the sub-nanometer scale. Precisely tunable gaps, as we expect, will be good candidates for future investigations of surface-enhanced Raman scattering, non-linear optics, and quantum plasmonics.

关键词： surface plasmon tunable plasmonic gap quantum plasmon surface-enhanced Raman scattering self-assembly nanoparticle array

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根皮素对免疫性肝炎小鼠的保护作用及机制

老年医学与保健 2024年第2期30卷 469-476页

作者：华倩樊晓明郭传勇蒋淼李正阳上海复旦大学附属金山医院消化科上海201508 上海同济大学附属上海市第十人民医院消化科上海200072

目的观察根皮素(Phloretin,PHL)对自身免疫性肝炎(autoimmune hepatitis,AIH)小鼠的保护作用及调控机制。方法SPF级Balb/C小鼠32只,随机分为对照(Control)组、刀豆蛋白A(concanavalin A,ConA)模型组、PHL低剂量组和PHL高剂量组。造模处理24 h后提取小鼠血清及肝脏组织,ELISA法检测血清转氨酶及炎症因子;HE染色观察肝脏组织病理学变化;TUNEL染色检测肝细胞凋亡;qRT-PCR检测转录表达水平;免疫组化和Western-blot检测肝组织炎症因子、自噬与凋亡蛋白及TRAF6-JNK通路信号蛋白表达水平。结果与正常对照组相比,AIH小鼠血清转氨酶及炎症因子表达显著升高(P<0.001),病理学见肝组织结构被广泛破坏,肝细胞大面积坏死及炎性细胞浸润。与ConA组相比,PHL组血清转氨酶及炎症因子水平下降(P<0.05),肝细胞结构完整,肝细胞坏死面积减少(P<0.05)。此外,与ConA组相比,PHL显著下调肝组织促凋亡蛋白及自噬蛋白的表达(P<0.05),下调TRAF6-JNK信号通路激活(P<0.05)。结论PHL可能通过减轻AIH小鼠肝细胞自噬和肝细胞凋亡,缓解AIH小鼠高炎症负荷,发挥对AIH小鼠的保护作用,可能是通过TRAF6-JNK信号通路发挥作用。

关键词：刀豆蛋白A 自身免疫性肝炎根皮素自噬凋亡 TRAF6 JNK

USP45 acts as an oncogene to regulate the proliferation of esophageal cancer cells

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Genes & Diseases 2024年第5期11卷 44-47页

作者： Kai Li qian Wang hua Bian Zhang Zhongjing College of Chinese Medicine Henan Key Laboratory of Zhang Zhongjing Formulae and Herbs for ImmunoregulationNanyang Institute of TechnologyNanyangHenan 473004China College of Orthopaedics and Traumatology Henan University of Chinese MedicineZhengzhouHenan 450046China

Deubiquitinases(DUBs)are a class of enzymes that are able to reverse the process of ubiquitination.1 Extensive research has revealed that there are more than 100 DUBs found in humans,which are classified into seven main families:ubiquitin-specific proteases(USPs),ubiquitin carboxyl-terminal hydrolases,the Machado-Joseph disease domain superfamily,the otubain/ovarian tumor-domain containing proteins,the ZUFSP(Zinc finger with UFM1-specific peptidase domain protein)family,the JAB1/MPN/MOV34 proteases,and the novel motif interacting with ubiquitin-containing DUB *** DUBs are cysteine proteases,except the JAB1/MPN/MOV34 proteases,which are Zn^(2+) metalloproteases.

关键词： esophageal cancer Zinc

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儿童肠病性肢端皮炎临床特征:附20例报告

皮肤性病诊疗学杂志 2024年第3期31卷 170-174页

作者：李纪兵李巍胡翠钱莹莹张婷吴亚芬钱华苏州大学附属儿童医院江苏苏州215000

目的了解儿童肠病性肢端皮炎(AE)的临床特征。方法对苏州大学附属儿童医院皮肤科门诊确诊的20例AE患儿的临床资料进行回顾性分析,并与20例体检健康儿童(对照组)比较血清中锌、铁元素水平。结果20例患儿中,男女比例为1∶1.22,平均年龄为(... 详细信息

目的了解儿童肠病性肢端皮炎(AE)的临床特征。方法对苏州大学附属儿童医院皮肤科门诊确诊的20例AE患儿的临床资料进行回顾性分析,并与20例体检健康儿童(对照组)比较血清中锌、铁元素水平。结果20例患儿中,男女比例为1∶1.22,平均年龄为(10.12±7.05)个月。皮疹常表现为红斑、斑片、鳞屑、糜烂、结痂,好发于口周、腹股沟、肛周、四肢末端区域,常伴发腹泻及脱发。患儿组血清锌元素水平低于对照组[(7.39±3.51)μmol/L vs(12.40±2.57)μmol/L,t=-5.15,P<0.001],铁元素水平低于对照组[(8.09±2.44)μmol/L vs(12.31±4.45)μmol/L,t=-3.17,P<0.001],差异均有统计学意义。锌治疗对所有患儿均有效。结论临床上患儿出现腔口周围皮炎、脱发、腹泻等症状时要警惕AE,血清锌、铁元素水平降低可辅助诊断。

关键词：肠病性肢端皮炎儿童临床特征

To enhance the reproduction of Phanerochaete chrysosporium by adding natural lixiviums in liquid medium

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Journal of Environmental Sciences 2003年第6期15卷 808-814页

作者： LIN Gang, WEN Xiang-hua, qian Yi (Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084, China. Department of Environmental Science and Engineering Tsinghua University Beijing 100084 Chin

Great promotion to the reproduction of white rot fungus Phanerochaete chrysosporium by adding natural lixiviums such as from wood, maize core and potato in liquid medium was found in this research. Incubated in the liquid medium contained 10 mg/L glucose as carbon source with natural lixiviums for three days, the production of mycelium pellet reaches more than 80 g/L, which is 5 times more than that of without natural lixiviums. Incubated in the liquid medium contained 5 mg/L glucose as carbon source with natural lixiviums for three days, the production of mycelium pellet can reach 69.5 g/L, while the production in the medium without natural lixiviums is very low. When the liquid medium contained 1—20 g/L glucose as carbon source, the production of mycelium pellet in 3 d can only reach 12.5 g/L to 14.5 g/L. The fungus in the medium with potato lixiviums are easily contaminated by other microorganisms and in the medium with maize core lixiviums are easily bulking, while in the medium with wood lixiviums are neither easily contaminated nor bulking. Medium with wood lixiviums can produce more pellet than other medium, endure contamination and keep better sedimentation capacity. So that, wood lixivium is better additive to the culture of white rot fungi in liquid medium. Addition of the mixture of wood, maize core and potato lixiviums is of advantage to the production of mycelium pellet. The difference of the production in the medium with different amount of wood lixiviums showed little in the first 3 d, while it expanded after 3 d. Wood lixiviums stimulate the growth of P. chrysosporium instead of supply organics which fungi need.

关键词： white rot fungi medium additive

基于代谢组学探讨七味癸宝颗粒治疗卵巢早衰的作用机制

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中国中药杂志 2024年第14期49卷 3887-3893页

作者：毛伟维朱晓奕刘雪玲徐忠坤姚逸刘承东黄风陶文华王彰禹钱华郭齐江苏大学医学院江苏镇江212013 江苏大学附属医院中医科江苏镇江212000 江苏康缘药业股份有限公司江苏连云港222047

该研究通过颈背部注射D-半乳糖(200 mg·kg^(-1))6周构建卵巢早衰(premature ovarian failure,POF)小鼠模型,小鼠随机分为正常(N)组、模型(M)组和七味癸宝颗粒组(A组,12.87 g·kg^(-1)),从造模第11天开始,A组在每天造模的基础上用七味... 详细信息

该研究通过颈背部注射D-半乳糖(200 mg·kg^(-1))6周构建卵巢早衰(premature ovarian failure,POF)小鼠模型,小鼠随机分为正常(N)组、模型(M)组和七味癸宝颗粒组(A组,12.87 g·kg^(-1)),从造模第11天开始,A组在每天造模的基础上用七味癸宝颗粒进行灌胃治疗32 d,M组和N组给予等体积生理盐水,采用代谢组学分析技术探讨七味癸宝颗粒治疗POF的作用机制。结果显示,与N组相比,M组小鼠双侧卵巢湿重降低,血清中LH和FSH水平升高,E2和PROG水平显著降低;服用七味癸宝颗粒治疗后,与M组相比,A组小鼠双侧卵巢湿重明显升高,血清中FSH和LH水平明显降低,E2水平明显升高。代谢组学分析发现N组和M组小鼠之间共鉴定出来55个差异代谢物(与N组相比,有14个上调,41个下调);在M组和A组之间共鉴定出82个差异代谢物(与M组相比,有56个上调,26个下调),其中有5个代谢物变化趋势与N vs M组一致。在排除这5个代谢物后,着重关注七味癸宝颗粒干预后发生变化的77个代谢物。主要涉及组氨酸代谢,甘氨酸、丝氨酸和苏氨酸代谢,甘油磷脂代谢通路。其中,肌肽、1-甲基-L-组氨酸、咪唑乙酸、胆碱、L-苏氨酸、β-羟基丙酮酸、磷脂酰胆碱和3-磷酸甘油为这3条代谢通路中的主要差异代谢物。所以,七味癸宝颗粒可能通过调节小鼠体内的氨基酸代谢和脂类代谢等对POF小鼠起到治疗作用。

关键词：七味癸宝颗粒卵巢早衰代谢组学生殖激素 D-半乳糖

Enhancing source domain availability through data and feature transfer learning for building power load forecasting

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Building Simulation 2024年第4期17卷 625-638页

作者： Fanyue qian Yingjun Ruan Huiming Lu hua Meng Tingting Xu College of Mechanical and Energy Engineering Tongji UniversityShanghai200092China United Automotive Electronic Systems Co. LtdShanghai201206China

During the initial phases of operation following the construction or renovation of existing buildings,the availability of historical power usage data is limited,which leads to lower accuracy in load forecasting and hinders normal ***,by transferring load data from similar buildings,it is possible to enhance forecasting ***,indiscriminately expanding all source domain data to the target domain is highly likely to result in negative transfer *** study explores the feasibility of utilizing similar buildings(source domains)in transfer learning by implementing and comparing two distinct forms of multi-source transfer ***,this study focuses on the Higashita area in Kitakyushu City,Japan,as the research *** buildings that exhibit the highest similarity to the target buildings within this area were selected for ***,the two-stage TrAdaBoost.R^(2) algorithm is used for multi-source transfer learning,and its transfer effect is ***,the application effects of instance-based(IBMTL)and feature-based(FBMTL)multi-source transfer learning are compared,which explained the effect of the source domain data on the forecasting accuracy in different transfer *** results show that combining the two-stage TrAdaBoost.R^(2) algorithm with multi-source data can reduce the CV-RMSE by 7.23%compared to a single-source domain,and the accuracy improvement is *** the same time,multi-source transfer learning,which is based on instance,can better supplement the integrity of the target domain data and has a higher forecasting ***,IBMTL tends to retain effective data associations and FBMTL shows higher forecasting *** findings of this study,which include the verification of real-life algorithm application and source domain availability,can serve as a theoretical reference for implementing transfer learning in load forecasting.

关键词： building power load multi-source transfer learning two-stage TrAdaBoost.R2 source domain availability

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一种自动检查等高线错、漏的方法和程序实现

测绘 2024年第3期47卷 128-132页

作者：程华谦刘璐罗昌琼王武生自然资源部第三航测遥感院四川成都610100

一直以来,等高线错、漏问题的检查通常以人机交互的方式进行,效率低且易漏检。本文根据等高线的自身特性及相邻等高线之间的规律,探索自动检查等高线错、漏问题的方法,并通过Python语言对其进行程序实现。试验结果表明,本文对等高线错... 详细信息

一直以来,等高线错、漏问题的检查通常以人机交互的方式进行,效率低且易漏检。本文根据等高线的自身特性及相邻等高线之间的规律,探索自动检查等高线错、漏问题的方法,并通过Python语言对其进行程序实现。试验结果表明,本文对等高线错、漏问题的自动化检查方法可行且结果可靠,具有应用推广意义。

关键词：等高线自动检查四川省1∶1万无图区域测图工程项目 Python