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基于CiteSpace知识图谱分析雄黄的研究热点与前沿

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中国中药杂志 2024年第9期49卷 2532-2543页

作者：武凤震王明镜吕妍付建华胡晓梅中国中医科学院博士后科研流动站北京100700 中国中医科学院西苑医院血液科北京100091 中国中医科学院西苑医院基础医学研究所北京100091 国家中医心血管病临床医学研究中心北京100091

该研究旨在应用知识图谱技术对雄黄研究现状和热点进行分析,为雄黄临床应用和未来深入研究提供指导。检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、Web of Science等5个数据库雄黄研究相关中、... 详细信息

该研究旨在应用知识图谱技术对雄黄研究现状和热点进行分析,为雄黄临床应用和未来深入研究提供指导。检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、Web of Science等5个数据库雄黄研究相关中、英文文献,利用NoteExpress文献管理软件对文献进行筛选,利用CiteSpace软件对作者、机构、关键词等进行可视化分析与展示。共纳入雄黄研究相关中文文献2879篇,英文文献194篇;《中国中药杂志》《Journal of Ethnopharmacology》分别是发文量最多的中、英文期刊;雄黄在皮肤病、血液病、癌症治疗中应用广泛;姜泓团队中、英文文献发文量均为最高;中国医科大学公共卫生学院、中国中医科学院分别是中、英文文献发文量最多的机构;雄黄研究主要集中在临床应用、作用机制、减毒增效等方面。雄黄研究的作者和机构主要集中在国内,其治疗血液病与癌症机制、雄黄减毒增效是现阶段研究热点,雄黄“异病同治”作用机制需要深入挖掘,亟需开展对雄黄多学科的交叉研究。该研究可为雄黄临床应用提供参考,为深入研究提供思路。

关键词：雄黄 CiteSpace 知识图谱临床应用减毒增效

Oral Arsenic-Containing Qinghuang Powder:A Potential Drug for Myelodysplastic Syndromes

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Chinese Journal of Integrative Medicine 2022年第8期28卷 762-768页

作者： MING Jing LIU Wei-yi xiao Hai-yan XU Yong-gang MA Rou hu xiao-mei Department of Hematology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China

Qinghuang Powder(QHP),an oral arsenic,has become an effective drug in the treatment of myelodysplastic syndromes(MDS)in Xiyuan Hospital,China Academy of Chinese Medical Sciences for many years,and the action mechanism of the compound or active ingredient AsSof QHP has been *** the relatively safety,chemotherapy-free and convenient oral profile,QHP is widely used in the clinical treatment for MDS patients,especially for elderly *** this review,the authors document the efficacy and safety of oral arsenic-containing compound QHP in the treatment of MDS,with a special focus on the association of efficacy of QHP with the cytogenetics,prognostic risk,DNA methylation,gene mutation,blood arsenic concentration,mechanism of action of AsSand the countermeasures against adverse reactions of gastrointestinal tract.

关键词： arsenic Qinghuang Powder myelodysplastic syndromes review Chinese medicine

Comparing Arsenic-Containing Qinghuang Powder and Low-Intensity Chemotherapy in Elderly Patients with Acute Myeloid Leukemia

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Chinese Journal of Integrative Medicine 2023年第9期29卷 832-837页

作者： WU Yu-he xiao Hai-yan QUAN Ri-cheng TANG Xu-dong LIU Wei-yi LYU Yan CHEN Zhuo LIU Chi hu xiao-mei Department of Hematology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China Graduate School China Academy of Chinese Medical SciencesBeijing100700China

Objective To compare the clinical effect of arsenic-containing Qinghuang Powder(QHP)and low-intensity chemotherapy(LIC)in treatment of elderly acute myeloid leukemia(eAML)*** Clinical data of 80 eAML patients treated at Xiyuan Hospital of China Academy of Chinese Medical Sciences from January 2015 to December 2020 were retrospectively *** treatment scheme was designed by real world study according to patients’preference,and patients were divided into a QHP group(35 cases)and a LIC group(45 cases).The median overall survival(mOS),1-,2-,and 3-year OS rates,and incidence of adverse events were compared between the two *** The mOS of 80 patients was 11 months,and the 1-,2-,and 3-year OS rates were 45.51%,17.96%,and 11.05%,*** QHP and LIC groups demonstrated no significant difference in mOS(12 months vs.10 months),1-(48.57%vs.39.65%),2-(11.43%vs.20.04%),and 3-year OS rates(5.71%vs.13.27%,all P>0.05).Moreover,the related factors of mOS demonstrated no significant difference in patients with age>75 years(11 months vs.8 months),secondary AML(11 months vs.8 months),poor genetic prognosis(9 months vs.7 months),Eastern Cooperative Oncology Group performance status score≥(10 months vs.7 months)and hematopoietic stem cell transplant comorbidity index≥4(11 months vs.7 months)between the QHP and LIC groups(all P>0.05).However,the incidence of myelosuppression was significantly lower in the QHP group than that in the LIC group(28.57%vs.73.33%,P<0.01).Conclusions QHP and LIC had similar survival rates in eAML patients,but QHP had a lower myelosuppression ***,QHP can be an alternative for eAML patients who do not tolerate LIC.

关键词： acute myeloid leukemia elderly Qinghuang Powder low-intensity chemotherapy Chinese medicine

R-matrix for the 8-Dimensional Spin Representation of Uq(so7)

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Acta Mathematica Sinica,English Series 2024年第2期40卷 485-497页

作者： Hong mei hu Nai Hong hu School of Mathematical Sciences Suzhou University of Science and TechnologySuzhou 215009P.R.China School of Mathematical Sciences MOE Key Laboratory of Mathematics and Engineering Applications&Shanghai Key Laboratory of PMMPEast China Normal UniversityShanghai 200241P.R.China

The purpose of the paper is to describe the solution to the quantum Yang-Baxter equation associated with the 8-dimensional spin representation Tsp of Uq(so7).The self-duality of Tsp and the symmetry of the corresponding braiding matrix are ***,the minimal polynomial of the braiding R-matrix of Tsp is presented explicitly in an ingenious method by taking advantage of nice features of the spin representation Tsp.

关键词： Braiding R-matrix spin module minimal polynomial

Investigation of mechanical and electrical characteristics of selfsensing pneumatic torsional actuators

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Science China(Technological Sciences) 2024年第1期67卷 130-142页

作者： xiao Wei hu DeAn hu GuoLiang xiao Yihua Key Laboratory of Conveyance and Equipment Ministry of EducationEast China Jiaotong UniversityNanchang 330013China Key Laboratory of Advanced Design and Simulation Techniques for Special Equipment Ministry of EducationHunan UniversityChangsha 410082China

Soft pneumatic actuators are one of the most promising actuation for soft robots,and great achievements have been *** it remains challenging to endow sensing capabilities to pneumatic actuators,especially for the sensing ability originating directly from the actuator ***,a self-sensing pneumatic torsional actuator(SPTA)is designed based on the electromagnetic induction effect and magnetically responsive *** SPTA can generate feedback voltage and current with the deformation,in which the sensing function comes from its inherent *** investigate the mechanical and electrical characteristics,an experimental platform and a finite element model are established,*** find that the torsion angle and output torque increase in nonlinear with the actuating *** maximum torsion angle is 66.35°,which is 84.34%of that for the actuator fabricated by pure *** maximum output torque(24.9 N mm)improves by 23.19%compared with the actuator made by pure *** regards the electrical characteristics,the maximum feedback voltage and current are 2.90μV and 29.50 nA when the SPTA is actuated by a pressure of−40 *** also demonstrate that the relationship between the torsion angle and the magnetic flux change is approximately ***,the number of turns of wires,magnetic powders contents,and magnetic direction on the feedback voltage and current are *** show that the feedback voltage and current can be enhanced by increasing the number of turns and magnetic powders *** envision that the SPTA would be promising for soft robots to realize their accuracy control and intelligentization.

关键词： pneumatic torsional actuators self-sensing feedback voltage finite element modeling soft robots

Application of the combination of 1,3-dichloropropene and dimethyl disulfide by soil injection or chemigation: effects against soilborne pests in cucumber in China

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Journal of Integrative Agriculture 2016年第1期15卷 145-152页

作者： MAO Lian-gang WANG Qiu-xia YAN Dong-dong LIU Peng-fei SHEN Jin FANG Wen-sheng hu xiao-mei LI Yuan OUYANG Can-bin GUO mei-xia CAO Ao-cheng Department of Pesticides Institute of Plant Protection Chinese Academy of Agricultural Sciences State Key Laboratory for Biology of Plant Diseases and Insect Pests Ministry of Agriculture

The combination of 1,3-dichloropropene＋dimethyl disulfide （1,3-D＋DMDS）, which forms a pre-plant soil fumigant, can provide a substitute for the environmentally unfriendly methyl bromide （MB）. Three greenhouse trials were performed to evaluate the root-knot nematode and soilborne fungi control efficacy in the suburbs of Beijing in China in 2010-2014. Randomized blocks with three replicates were designed in each trial. The combination of 1,3-D＋DMDS （10＋30 g m-2） significantly controlled Meloidogyne incognita, effectively suppressed the infestation of Fusarium oxysporum and Phytophthora spp., and successfully provided high commercial fruit yields （equal to MB but higher than 1,3-D or DMDS）. The fumigant soil treatments were significantly better than the untreated controls. These results indicate that 1,3-D＋DMDS soil treatments can be applied by soil injection or chemigation as a promising MB alternative against soilborne pests in cucumber in China.

关键词： soil fumigation 1,3-dichloropropene dimethyl disulfide soilborne pest cucumber

Characterizations of semihoops based on derivations

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 291-310页

作者： WANG mei ZHANG xiao-hong School of Electrical and Control Engineering Shaanxi University of Science and TechnologyXi'an 710021China School of Arts and Sciences Shaanxi University of Science and TechnologyXi'an 710021China School of Mathematics and Statistics Weinan Normal UniversityWeinan 714099China

In this paper,we discuss the related properties of some particular derivations in semihoops and give some characterizations of ***,we prove that every Heyting algebra is isomorphic to the algebra of all multiplicative derivations and show that every Boolean algebra is isomorphic to the algebra of all implicative ***,we show that the sets of multiplicative and implicative derivations on bounded regular idempotent semihoops are in oneto-one correspondence.

关键词： (prelinear)semihoop derivation Heyting algebra Galois connection

An Improved Golden Jackal Optimization Algorithm Based on Multi-strategy Mixing for Solving Engineering Optimization Problems

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Journal of Bionic Engineering 2024年第2期21卷 1092-1115页

作者： Jun Wang Wen-chuan Wang Kwok-wing Chau Lin Qiu xiao-xue hu Hong-fei Zang Dong-mei Xu College of Water Resources North China University of Water Resources and Electric PowerZhengzhou450046People’s Republic of China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongPeople’s Republic of China

Nowadays,optimization techniques are required in various engineering domains to find optimal solutions for complex *** a result,there is a growing tendency among scientists to enhance existing nature-inspired algorithms using various evolutionary strategies and to develop new nature-inspired optimization methods that can properly explore the feature *** recently designed nature-inspired meta-heuristic,named the Golden Jackal Optimization(GJO),was inspired by the collaborative hunting actions of the golden jackal in nature to solve various challenging ***,like other approaches,the GJO has the limitations of poor exploitation ability,the ease of getting stuck in a local optimal region,and an improper balancing of exploration and *** overcome these limitations,this paper proposes an improved GJO algorithm based on multi-strategy mixing(LGJO).First,using a chaotic mapping strategy to initialize the population instead of using random parameters,this algorithm can generate initial solutions with good diversity in the search ***,a dynamic inertia weight based on cosine variation is proposed to make the search process more realistic and effectively balance the algorithm's global and local search ***,a position update strategy based on Gaussian mutation was introduced,fully utilizing the guidance role of the optimal individual to improve population diversity,effectively exploring unknown regions,and avoiding the algorithm falling into local *** evaluate the proposed algorithm,23 mathematical benchmark functions,CEC-2019 and CEC2021 tests are *** results are compared to high-quality,well-known optimization *** results of the proposed method are compared from different points of view,including the quality of the results,convergence behavior,and *** superiority and high-quality performance of the proposed method are demonstrated by comparing the ***,to demonstrate

关键词： Golden jackal optimization Chaotic mapping Dynamic inertia weight Dimensional Gaussian variation Muskingum

CRD-CGAN:category-consistent and relativistic constraints for diverse text-to-image generation

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Frontiers of Computer Science 2024年第1期18卷 61-75页

作者： Tao hu Chengjiang LONG Chunxia xiao College of Intelligent Systems Science and Engineering Hubei Minzu UniversityEnshi 445000China School of Computer Science Wuhan UniversityWuhan 430072China Key Laboratory of Performing Art Equipment&System Technology Ministry of Culture and TourismBeijing 100007China Meta Reality Labs BurlingameCA94010USA

Generating photo-realistic images from a text description is a challenging problem in computer *** works have shown promising performance to generate synthetic images conditional on text by Generative Adversarial Networks(GANs).In this paper,we focus on the category-consistent and relativistic diverse constraints to optimize the diversity of synthetic *** on those constraints,a category-consistent and relativistic diverse conditional GAN(CRD-CGAN)is proposed to synthesize K photo-realistic images *** use the attention loss and diversity loss to improve the sensitivity of the GAN to word attention and ***,we employ the relativistic conditional loss to estimate the probability of relatively real or fake for synthetic images,which can improve the performance of basic conditional ***,we introduce a category-consistent loss to alleviate the over-category issues between K synthetic *** evaluate our approach using the Caltech-UCSD Birds-200-2011,Oxford 102 flower and MS COCO 2014 datasets,and the extensive experiments demonstrate superiority of the proposed method in comparison with state-of-the-art methods in terms of photorealistic and diversity of the generated synthetic images.

关键词： text-to-image diverse conditional GAN relativi-stic category-consistent