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Application of Laparoscopic Extralevator Abdominoperineal Excision in Locally Advanced Low Rectal Cancer

Chinese Medical Journal 2015年第10期128卷 1340-1345页

作者： Yan-Lei Wang Yong Dai Jin-Bo Jiang hui-Yang yuan san-yuan hu Department of General Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China

Background：When compared with conventional abdominoperineal resection （APR）,extralevator abdominoperineal excision （ELAPE） has been demonstrated to reduce the risk of local recurrence for the treatment of locally advanced low rectal *** with the laparoscopic technique,laparoscopic ELAPE （LELAPE） has the potential to reduce invasion and hasten postoperative *** this study,we aim to investigate the advantages of LELAPE in comparison with conventional ***：From October 2010 to February 2013,23 patients with low rectal cancer （T3-4N0-2M0） underwent LELAPE;while during the same period,25 patients were treated with conventional *** patient characteristics,intraoperative data,postoperative complications,and follow-up results were retrospectively compared and ***：The basic patient characteristics were similar;but the total operative time for the LELAPE was longer than that of the conventional APR group （P =0.014）.However,the operative time for the perineal portion was comparable between the two groups （P =0.328）.The LELAPE group had less intraoperative blood loss （P =0.022）,a lower bowel perforation rate （P =0.023）,and a positive circumferential margin （P =0.028）.Moreover,the patients,who received the LELAPE,had a lower postoperative Visual Analog Scale,quicker recovery of bowel function （P =0.001）,and a shorter hospital stay （P =0.047）.However,patients in the LELAPE group suffered more chronic perineal pain （P =0.002）,which may be related to the coccygectomy （P =0.033）.Although the metastasis rate and mortality rate were similar between the two groups,the local recurrence rate of the LELAPE group was statistically improved （P =0.047）.Conclusions：When compared with conventional APR,LELAPE has the potential to reduce the risk of local recurrence,and decreases operative invasion for the treatment of locally advanced low rectal cancer.

关键词： Abdominoperineal Resection Circumferential Margin Extralevator Abdominoperineal Excision Laparoscopy Low Rectal Cancer

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新型WN纤维透明电极的制备及透光导电性能

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现代技术陶瓷 2024年第1期45卷 149-159页

作者：陈冲胡三元廖敦明严有为王新云李和平华中科技大学材料科学与工程学院材料成形与模具技术全国重点实验室武汉430074 深圳华中科技大学研究院深圳518057

纤维透明电极兼具高透光与高导电性,有望取代传统锡掺杂氧化铟(简称ITO)成为新一代透明电极材料。金属纤维虽具有高导电性,但在受热或酸碱腐蚀条件下其性能急剧下降,应用环境受限。针对上述问题,本文采用电纺丝结合氮化热处理工艺制备... 详细信息

纤维透明电极兼具高透光与高导电性,有望取代传统锡掺杂氧化铟(简称ITO)成为新一代透明电极材料。金属纤维虽具有高导电性,但在受热或酸碱腐蚀条件下其性能急剧下降,应用环境受限。针对上述问题,本文采用电纺丝结合氮化热处理工艺制备出新型WN导电纤维,进一步通过近场直写方法实现纤维的有序排列与WN纤维透明电极的图案化构筑,以获得高透光高导电且耐热耐腐蚀的新型高性能透明电极。研究结果表明,WN纤维的导电性随氮化温度的升高而增大,900℃氮化制备的WN纤维的电导率高达2189 S/cm。通过近场直写可以有效调控WN纤维透明电极的网格结构,进而调控其透光性与导电性。当网格间距为200μm时,对应透明电极的透光率高达94%以上,方阻低至6.0Ω/sq,性能优于目前报道的金属纤维透明电极。与金属纤维相比,WN纤维透明电极还具有优异的耐热与耐腐蚀性,在160℃氧化16h,方阻仅增加8%,在pH值为1~13的酸碱溶液中腐蚀1min,方阻增幅≤3%。

关键词： WN 纳米纤维透明电极电纺丝

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A regression approach for seismic first-break picking

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Petroleum Science 2024年第3期21卷 1584-1596页

作者： huan yuan san-Yi yuan Jie Wu Wen-Jing sang Yu-He Zhao CNPC Key Laboratory of Geophysical Exploration China University of Petroleum(Beijing)Beijing 102249China Research Institute of Petroleum Exploration&Development—Northwest(NWGI) Key Laboratory of reservoir characterization of CNPCPetroChinaLanzhou 730020GansuChina

The picking efficiency of seismic first breaks(FBs)has been greatly accelerated by deep learning(DL)***,the picking accuracy and efficiency of DL methods still face huge challenges in low signal-to-noise ratio(SNR)*** address this issue,we propose a regression approach to pick FBs based on bidirectional long short-term memory(Bi LSTM)neural network by learning the implicit Eikonal equation of 3D inhomogeneous media with rugged topography in the target *** employ a regressive model that represents the relationships among the elevation of shots,offset and the elevation of receivers with their seismic traveltime to predict the unknown FBs,from common-shot gathers with sparsely distributed *** from image segmentation methods which automatically extract image features and classify FBs from seismic data,the proposed method can learn the inner relationship between field geometry and *** addition,the predicted results by the regressive model are continuous values of FBs rather than the discrete ones of the binary *** picking results of synthetic data shows that the proposed method has low dependence on label data,and can obtain reliable and similar predicted results using two types of label data with large *** picking results of9380 shots for 3D seismic data generated by vibroseis indicate that the proposed method can still accurately predict FBs in low SNR *** subsequent stacked profiles further illustrate the reliability and effectiveness of the proposed *** results of model data and field seismic data demonstrate that the proposed regression method is a robust first-break picker with high potential for field application.

关键词： First-break picking Low signal-to-noiseratio Regression BiLSTM Traveltime Geometry Noisy seismic data

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Expression of farnesyltransferase in primary liver cancer

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Chinese Medical Journal 2012年第14期125卷 2427-2431页

作者： SUI Guo-de ZHANG Guang-yong NIU Zhao-jian hu san-yuan Department of General Surgery Qilu Hospital of ShandongUniversity Jinan Shandong 250012 China

Background Primary liver cancer （PLC） is a common malignant tumor. Over the past decade, although farnesyltransferase （FTase） has emerged as a significant target for anticancer therapies and has become a hotspot of cancer research, its exact mechanism of action remains unknown. The aim of this study was to investigate the expression of FTase in PLC and its role in the development of PLC. Methods Expression of FTase was detected by real-time fluorescent quantitative-polymerase chain reaction （FQ-PCR） in cancer and surrounding normal tissues from 32 patients with PLC. Results Expression of FTase mRNA in PLC was significantly higher than that in normal hepatic tissues （P 〈0.001）. Overexpression of FTase was as high as 87.5%. The positive rate for FTase mRNA in the high tendency to metastatic recurrence group was obviously higher than that in the low tendency to metastatic recurrence group （P=0.02）. The positive rate for FTase mRNA in patients with metastatic recurrence during postoperative follow-up was also significantly higher than that in those without metastatic recurrence （P=-0.01）. Conclusions The level of FTase mRNA expression in cancer tissues is much higher than in normal tissues. FTase may play an important role in the genesis and development of PLC and may be one of the reliable markers for the metastatic activity gained by liver tumor cells. FTase could be used clinically in predicting metastatic recurrence of PLC

关键词： primary liver cancer, farnesyltransferase fluorescent quantitative-polymerase chain reaction

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Trial application of the envelope method to the potential ambiguity problem

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Nuclear Science and Techniques 2024年第1期35卷 73-80页

作者： Li-yuan hu Yu-Shou Song Fundamental Science on Nuclear Safety and Simulation Technology Laboratory Harbin Engineering UniversityHarbin 150001China College of Nuclear Science and Technology Harbin Engineering UniversityHarbin 150001China Key Laboratory of Nuclear Safety and Advanced Nuclear Energy Technology Ministry of Industry and Information TechnologyHarbin 150001China

The optical potential ambiguity is a long-standing problem in the analysis of elastic scattering *** a specific collid-ing system,ambiguous potential families can lead to different behaviors in the nearside and farside scattering *** contrast,the envelope method can decompose the experimental data into two components with negative and positive deflection angles,***,a question arises as to whether the comparison between the calculated nearside(or farside)component and the derived positive-deflection-angle(or negative-deflection-angle)component can help analyze the potential ambiguity *** this study,we conducted a trial application of the envelope method to the potential ambiguity *** envelope method was improved by including uncertainties in the experimental *** colliding systems of 16O+28Si at 215.2 MeV and 12C+12C at 1016 MeV were considered in the *** each colliding system,the angular distribution experimental data were described nearly equally well by two potential sets,one of which is“surface transpar-ent”and the other is *** calculated angular distributions were decomposed into nearside and farside scattering *** the improved envelope method,the experimental data were decomposed into the positive-deflection-angle and negative-deflection-angle components,which were then compared with the calculated nearside and farside *** capability of the envelope method to analyze the potential ambiguities was also discussed.

关键词： Elastic scattering Optical potential ambiguities Envelope method Nearside/farside decomposition

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Correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2

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Chinese Medical Journal 2013年第10期126卷 1925-1929页

作者： ZHOU Shao-fei hu san-yuan MA Lei MIAO Lei MAO Wei-zheng Department of (Jeneral Surgery Qilu Hospital Shandong UniversityJinan Shandong 250012 China Department o1: General Surgery Qingdao Municipal HospitalQingdao Shandong 266071 China

Background The relationship between the presence of metalloproteinases and thyroid cancer remains unknown, and many controversies still exist in this field. The objective of this study was to investigate the correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metall0Proteinase-2. Methods The correlations were studied bY detecting the levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloProteinase-1, and tissue inhibitor of metalloproteinase-2 by enzyme-linked immunosorbant assay and reverse-transcription polymerase chain reaction in the peripheral blood of 30 patients with papillary thyroid carcinoma, 27 patients with benign thyroid disease, and 25 hea !hy vo!unteers. Results The leve!s of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2 in the peripheral blood of patients with papillary thyroid carcinoma were significantly higher than those in the peripheral blood of patients with benign thyroid disease and healthy volunteers （P 〈0.05）. However, there were no significant differences between patients with benign thyroid disease and healthy volunteers （P 〉0.05）. The accuracy of detection by both enzyme-linked immunosorbant assay and reverse-transcription polymerase chain reaction in the papillary thyroid cancer group was 83.33%. Conclusions The levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2 in the peripheral blood are helpful in identifying thyroid carcinoma and aid in preoperative assessment.

关键词： thyroid carcinoma matrix metalloproteinase-2 matrix metalloproteinase-9 tissue inhibitor of metalloproteinase-1 tissue inhibitor of metalloproteinase-2

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MAUN:Memory-Augmented Deep Unfolding Network for Hyperspectral Image Reconstruction

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1139-1150页

作者： Qian hu Jiayi Ma yuan Gao Junjun Jiang Yixuan yuan Electronic Information School Wuhan UniversityWuhan 430072China School of Computer Science and Technology Harbin Institute of TechnologyHarbin 150001China Department of Electronic Engineering Chinese University of Hong KongHong Kong 999077China

Spectral compressive imaging has emerged as a powerful technique to collect the 3D spectral information as 2D *** algorithm for restoring the original 3D hyperspectral images(HSIs)from compressive measurements is pivotal in the imaging *** approaches painstakingly designed networks to directly map compressive measurements to HSIs,resulting in the lack of interpretability without exploiting the imaging *** some recent works have introduced the deep unfolding framework for explainable reconstruction,the performance of these methods is still limited by the weak information transmission between iterative *** this paper,we propose a Memory-Augmented deep Unfolding Network,termed MAUN,for explainable and accurate HSI ***,MAUN implements a novel CNN scheme to facilitate a better extrapolation step of the fast iterative shrinkage-thresholding algorithm,introducing an extra momentum incorporation step for each iteration to alleviate the information ***,to exploit the high correlation of intermediate images from neighboring iterations,we customize a cross-stage transformer(CSFormer)as the deep denoiser to simultaneously capture self-similarity from both in-stage and cross-stage features,which is the first attempt to model the long-distance dependencies between iteration *** experiments demonstrate that the proposed MAUN is superior to other state-of-the-art methods both visually and *** code is publicly available at https://***/huQ1an/MAUN.

关键词： Deep folding iteration

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Hand-assisted laparoscopic splenectomy for splenomegaly:a comparative study with conventional laparoscopic splenectomy

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Chinese Medical Journal 2007年第1期120卷 41-45页

作者： WANG Ke-xin hu san-yuan ZHANG Guang-yong CHEN Bo ZHANG Hai-feng Department of General Surgery Qilu Hospital of ShandongUniversity Jinan 250012 China

Background Laparoscopic splenectomy （LS） has been considered as the standard approach to remove a normal-sized spleen, but it is facing technical challenges when applied to splenomegaly. Hand-assisted laparoscopic technique was designed to facilitate the performance of difficult laparoscopic procedure. This study was aimed to evaluate the efficacy and superiority of hand-assisted laparoscopic splenectomy （HALS） for splenomegaly. Methods From November 1994 to January 2006, 36 patients with splenomegaly （final spleen weight 〉700 g） were treated with laparoscopic operations for splenectomy in our hospital. Conventional LS was performed in 16 patients （7 men and 9 women, group 1） and HALS in the other 20 patients （12 men and 8 women, group 2）. The patients＇ features, intraoperative details and the postoperative outcomes in the both groups were compared. Results The both groups were comparable in the terms of patient＇s age （（38±12） years vs （43±14）years, P〉0.05）, the greatest splenic diameter （（24±5）cm vs （27±7）cm, P〉0.05）, preoperative platelet count （（118±94）×10^9/L vs （97±81）×10^9/L P〉0.05） and diagnosis. Compared with LS group, operation time （（195±71） minutes vs （141±64） minutes, P〈0.05） was shorter, intraoperative blood loss （（138±80）ml VS （86±45）ml, P〈0.05） and conversion rate （4/16 vs 0/20, P〈0.05） were lower, but hospital stay （（5.3±3.8） days vs （7.4±1.6） days, P〈0.05） was longer in HALS group. There was no significant difference in the aspects of intraoperative and postoperative complication rate （2/16 vs 0/20, P〉0.05） or recovery time of gastrointestinal function （（16.3±11.6） hours vs （18.7±8.1）hours, p〉0.05） between the two groups. Conclusions In the cases of splenomegaly, HALS significantly facilitates the surgical procedure and reduces the operational risk, while maintaining the advantages of conventional LS. HALS is more feasible and more effective than conventional LS for the removal of splenomegaly of splenomegaly.

关键词： splenomegaly laparoscopy splenectomy surgical procedures, minimally invasive

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Intraseasonal variability of the Kuroshio observed via mooring at 18°N

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Journal of Oceanology and Limnology 2024年第2期42卷 468-483页

作者： Xin yuan Qingye WANG Jie MA Shijian hu Dunxin hu Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China Laoshan Laboratory Qingdao 266237China Center for Ocean Mega-Science Chinese Academy of SciencesQingdao 266071China

Insufficient observations near the origin of the Kuroshio have led to incomplete understanding of the intraseasonal variability(ISV)of the *** measurements of the Kuroshio velocity were performed with an array of three profiler moorings(122.7°E,123°E,and 123.3°E)along 18°N from January 2018 to February *** ISV of the Kuroshio at 18°N was investigated based on a combination of mooring observations and global high-resolution HYbrid Coordinate Ocean Model reanalysis *** estimated time-averaged transport in the upper 350 m across the observation transect was 6.5±2.6 Sv(1.0 Sv=10^(6)m^(3)/s).Two significant ISV peaks at 50-60 and~100 d were recognized in the power spectra of the meridional velocity and *** analysis indicated that the ISV at 50-60 d was caused by westward-propagating eddies at average propagation speed of~13 cm/s and wavelength of~635 *** ISV peak at~100 d was mainly caused by northward-propagating eddies generated in the North Equatorial Current *** investigation indicated that the ISV of the Kuroshio at 18°N is dominated by meridional transport,rather than by the zonal migration of the Kuroshio main *** findings provide a better understanding of the ISV of the Kuroshio east of Luzon Island.

关键词： intraseasonal variability(ISV) Kuroshio mooring observation eddy

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Current status of early gastric cancer screening research

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Cancer Biology & Medicine 2024年第3期21卷 218-222页

作者： Can hu Li yuan Xiangdong Cheng Department of Gastric surgery Zhejiang Cancer HospitalHangzhou Institute of Medicine(HIM)Chinese Academy of SciencesHangzhouZhejiang 310022China Key Laboratory of Prevention Diagnosis and Therapy of Upper Gastrointestinal Cancer of Zhejiang ProvinceHangzhou 310022China Zhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer Zhejiang Cancer HospitalHangzhou 310022China

Gastric cancer is a predominant threat to the health and well-being of China's residents. Data from the World Health Organization(WHO) in 2020 revealed that gastric cancer in China notably accounted for 44.0% of new c... 详细信息

关键词： cancer Gastric gastric

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