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Software Engineering Technology for the 21^(st) Century

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Wuhan University Journal of Natural sciences 2001年第Z1期6卷 152-158页

作者： Cheng hu Institute of Software, chinese academy of sciences beijing 100080, china Institute of Software Chinese Academy of Sciences Beijing 100080 China

In this paper we will discuss the software engineering technology for the 21 st century. First we review development over the last half century, overview application requirement and environment, accept a challenge. Then we outline following software engineering techniques: 1) Process;2) Analysis;3) Design;4) UML;5) Component;6) Java +XML;7) Integrated;8) Quality(ISO9000&CMM).

关键词： software engineering object oriented component Java UML CMM ISO9000

Recent advances in the data analysis method of functional magnetic resonance imaging and its applications in neuroimaging

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Progress in Natural Science:Materials International 2006年第8期16卷 785-795页

作者： TIAN Jie, YANG Lei and hu Jin (Institute of Automation, chinese academy of sciences, beijing 100080, china Graduate School of chinese academy of sciences, beijing 100039, china) Institute of Automation Chinese Academy of Sciences Beijing 100080 China. Graduate School of chinese academy of sciences Beijing 100039 China

Functional magnetic resonance imaging (fMRI) has opened a new area to explore the human brain. The fMRI can reveal the deep insights of spatial and temporal changes underlying a broad range of brain function, such as motor, vision, memory and emotion, all of which are helpful in the clinical investigation. In this paper, we introduce some recent-developed algorithms for fMRI signal detection such as model-driven method (general linear model, deconvolution model, non-linear model, etc. ) and data-driven method (principle component analysis, independent component analysis, self-organization mapping, clustered constrained non-negative matrix factorization, etc. ). We also propose several important applications of neuroimaging and point out their shortcomings and future perspectives.

关键词： fMR1 data analysis neuroimaging.

Community-based prevention and treatment of cardiovascular diseases

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Journal of Geriatric Cardiology 2024年第3期21卷 315-322页

作者： Sheng-Shou hu The Writing Committee of the Report on Cardiovascular Health and Diseases in china Fuwai Hospital National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

The Annual Report on Cardiovascular Health and Diseases in china(2022)intricate landscape of cardiovascular health in *** is the third section of the report with a specific focus on community-based prevention and treatment of cardiovascular diseases(CVD).This section of the report underscores the importance of initiatives outlined in the"Healthy china 2030 Plan,"emphasizing the comprehensive prevention and control strategy for chronic diseases.A key aspect of this plan involves the establishment of national demonstration areas aimed at comprehensive prevention and control of chronic *** 2020,488 such areas had been set up across china,surpassing the initial target and covering a significant proportion of counties and *** report highlights the successful implementation of these strategies in Lishan district,Anshan city,where demonstration areas for comprehensive prevention and control of chronic diseases were launched in *** the course of seven years,the number of healthy units increased substantially,leading to improvements in managing risk factors for CVD among *** reductions in prevalence rates of overweight,obesity,smoking,passive smoking,and drinking were observed,along with the development of healthier behaviors among ***,Qiaokou district in Wuhan City,designated as a national demonstration area in 2014,implemented comprehensive public health promotion ***,special clinics for hypertension intervention were established,contributing to an increase in self-reported rates of hypertension,a slight decrease in prevalence,and a remarkable improvement in the control rate among treated ***,these efforts underscore the effectiveness of community-based approaches in driving positive health outcomes and advancing the comprehensive prevention and control of chronic diseases,particularly cardiovascular diseases,in china.

关键词： prevention district treatment

Heart failure in china:epidemiology and current management

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Journal of Geriatric Cardiology 2024年第6期21卷 631-641页

作者： Sheng-Shou hu the Writing Committee of the Report on Cardiovascular Health and Diseases in china Fuwai Hospital National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

The Annual Report on Cardiovascular Health and Diseases in china(2022)intricate landscape of cardiovascularhealth in *** connection with the previous section,this sixth section of the report offers a comprehensive analysis of heart failure(HF)in *** is one of the most important cardiovascular disease in the 21st *** mortality is equivalent to that of *** is an important public health problem that seriously affects the health of chinese *** recent years,with the deepeningof understanding,the change of treatment principles,the innovation of treatment methods and the update of treatment guidelines,the in-hospital mortality of HF patients has declined,and the long-term prognosis is also ***,there are stilldifferences in the management level of HF among different hospitals in *** to improve the standardized diagnosis andtreatment level of HF in china remains an important challenge.

关键词： epidemiology diagnosis treatment

Cardiovascular Risk Factors in china

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Journal of Geriatric Cardiology 2024年第2期21卷 153-199页

The Annual Report on Cardiovascular Health and Diseases in china(2022) intricate landscape of cardiovascular health in china. This section dissects cardiovascular risk factors in china which including hypertension, dyslipidemia, diabetes mellitus, chronic kidney disease, metabolic syndrome and air pollution. Hypertension prevalence has steadily increased in china,with efforts to control it facing challenges in achieving optimal rates, especially in rural areas. Interventions like salt substitutes and intensive blood pressure control show promise but need improvement. Abnormal lipid levels, indicative of dyslipidemia,have risen significantly, posing a risk for cardiovascular diseases. Despite efforts, many patients struggle to achieve target lipid levels, necessitating improved treatment strategies. Both type 1 and type 2 diabetes mellitus affect millions of adults in china,with long-term complications adding to the disease burden. Early intervention and effective management are crucial to mitigate its impact. Prevalent among older adults, chronic kidney disease is associated with diabetes mellitus, hypertension, and cardiovascular diseases, necessitating comprehensive management approaches. The prevalence of metabolic syndrome, characterized by a cluster of risk factors, has increased in both adults and adolescents, calling for lifestyle modifications and public health interventions. Ambient and household air pollution remain significant environmental risk factors, despite some improvements in air quality. Continued efforts to reduce emissions are essential for mitigating associated health risks. Addressing these risk factors requires a multifaceted approach, including public health initiatives, policy interventions, and individual-level strategies to promote healthy lifestyles and reduce environmental exposures. Surveillance and research efforts are crucial for monitoring trends and developing effective strategies to lessen the burden of cardiovascular diseases in

关键词： landscape adding spite

Pulmonary embolism and deep venous thrombosis in china

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Journal of Geriatric Cardiology 2024年第8期21卷 775-778页

The Annual Report on Cardiovascular Health and Diseases in china(2022) intricate landscape of cardiovascular health in *** connection with the previous section,this eighth section of the report offers a comprehensive analysis of pulmonary embolism and deep venous *** recent years,research in the field of pulmonary vessel in china has made great progress.A number of nationwide multi-center registry research results have filled the gaps in the epidemiology,diagnosis and treatment of pulmonary hypertension and venous *** types of pulmonary hypertension still need attention to the identification of risk factors and/or risk stratification,and venous thromboembolism needs attention in the prevention and the overall management inside and outside *** the future,we look forward to the publication of more high-quality research in china,which could be able to improve relevant guidelines for pulmonary vascular diseases both domestically and inter-nationally.

关键词： epidemiology prevention diagnosis

The Multifractal Analysis of the Occupation Measure of a Lévy Process

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Wuhan University Journal of Natural sciences 2000年第3期5卷 253-256页

作者： hu Xiao\|yu Institute of Applied Mathematics, chinese academy of sciences, beijing 100080, china Institute of Applied Mathematics Chinese Academy of Sciences Beijing 100080 China

We introduce the results on the multifractal structure of the occupation measures of a Brownian Motion, a stable process, a general subordinator and a stochastic process derived from random reordering of the Cantor se... 详细信息

关键词： occupation measure Levy process Brownian motion stable process subordinator

CONSTRUCTION OF A PRECONDITIONER FOR DOMAIN DECOMPOSITION METHODS WITH POLYNOMIAL LAGRANGIAN MULTIPLIERS

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Journal of Computational Mathematics 2001年第2期19卷 213-224页

作者： Qi-ya hu (Institute of Computational Mathematics, academy of Mathematics and Systems sciences, chinese academy of sciences, beijing 100080, china) Guo-ping Liang Jin-zhao Liu (Institute of Mathematics, academy of Mathematics and Systems sciences, chinese 中科院计算数学与工程计算数学所北京 100080 中科院数学所北京 100080

In this paper we consider domain decomposition methods with polynomial Lagrangian multipliers to two-dimentional elliptic problems, and construct a kind of simple preconditioners for the corresponding interface equation. It will be shown that condition number of the resulting preconditioned interface matrix is almost optimal (namelys it has only logarithmic growth with dimension of the local interface space).

关键词： Domain Decomposition Non-matching grids Lagrangian multipliers Preconditioner Condition number.

Structural Analysis and Identification of Cis-Elements of Rice osRACD Gene

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Acta Biochimica et Biophysica Sinica 2004年第3期36卷 191-198页

作者： Yun-Zhe XU, Rui-Lin YOU and Nai-hu WU Institute of Genetics and Developmental Biology, chinese academy of sciences, beijing 100080, china 2College of Life sciences, Peking University, beijing 100871, china Institute of Genetics and Developmental Biology Chinese Academy of Sciences College of Life sciences Peking University

The osRACD gene correlated with fertility transformation in the photoperiod sensitive genic male sterile rice (PGMR), Nongken 58S, encoded a rice (Oryza sativa L. ssp. japonica) small GTPase belonging to the Rac/Rho family. Inverse PCR was performed to amplify a fragment about 1.4 kb in 5' upstream region of the osRACD promoter. Deletion mutation and gel mobility shift assay characterized two fragments (–799 to –686 nt, and –686 to –431 nt) in the osRACD promoter that could be involved in its transcriptional regulation. When these two deletion fragments were used as probe respectively, a retarded band appeared in the nuclear extracts of fertile 58S rice under short day (58S-SD). Whereas no retarded band was shown in the nuclear extracts of sterile 58S rice under long day (58S-LD). Competition assay indicated that the factors in the retarded bands binding to these two fragments were the same trans-acting factor (termed rice factor, RF). The binding affinity of RF was affected by phosphorylation and was higher in SD-growth rice than that of LD-growth rice.

关键词： photoperiod-sensitive male genic sterile rice osRACD gene photoperiod fertility transformation cis-element